scholarly journals Microgravity and Space Medicine

2021 ◽  
Vol 22 (13) ◽  
pp. 6697
Author(s):  
Daniela Grimm

This Special Issue (SI), “Microgravity and Space Medicine”, covers research articles and reviews focusing on gravitational biology, cancer research and space medicine. It includes publications investigating the effects of altered gravity conditions on mammalian cells and humans during real microgravity (r-μg) on the International Space Station (ISS) and parabolic flights (PFs) [...]


Author(s):  
Kris See

What will be the future of medicine a decade from now? What difficulties related with preventing, detecting, and treating diseases will have been unraveled? How will space medicine make an impact?. Today as compared to previously, it is the role of space medicine to gear up astronauts sufficiently for their missions and also to maintain their health in good condition. Moreover, the exclusive and new environmental surroundings existing in space continuously propose prospects to validate theories and assumptions established by earth-based medicine and recognize likely mistakes and disparities, as we have been observing approximately more than a decade with outcomes for example, from the International Space Station.



2003 ◽  
Vol 16 (2) ◽  
pp. 91-95
Author(s):  
Kira Bacal ◽  
Bruce M. Frey

Medical care available to astronauts on the International Space Station has been affected by limitations on funding, space and weight availability, and crew training. A Space Medicine Patient Condition Database (PCDB) was designed to enhance inventory control, resource selection, protocol standardization, evidence-based medicine, on-orbit diagnostic skills, and materiel management. The first step in the PCDB creation was the identification of the medical conditions anticipated among the astronaut population in the flight environment. Military databases, previous spaceflight experience, and analog populations were used to create this listing. The PCDB then linked these individual conditions with the current resources available on orbit to treat them. Other features include a resource gauge, item location information, diagnosis coding, and built-in reference capabilities. Currently in the second phase of development, specific, evidence-based treatment protocols are being developed and evaluated in comparison with the terrestrial medicine standard of care. By documenting on-orbit medical systems and their associated terrestrial standards, the PCDB enables the prioritization and allocation of limited resources. In the final phase of the project, the PCDB will make use of decision support software to enhance diagnostic determination and provide an operational tool for the crew and mission teams.



2009 ◽  
Vol 65 (5-6) ◽  
pp. 603-612 ◽  
Author(s):  
Anatoly I. Grigoriev ◽  
Richard S. Williams ◽  
Jean-Marc Comtois ◽  
Volker Damann ◽  
Shoichi Tachibana ◽  
...  


2005 ◽  
Author(s):  
Danielle Paige Smith ◽  
Vicky E. Byrne ◽  
Cynthia Hudy ◽  
Mihriban Whitmore




2020 ◽  
Vol 91 (1) ◽  
pp. 41-45 ◽  
Author(s):  
Virginia. E. Wotring ◽  
LaRona K. Smith

INTRODUCTION: There are knowledge gaps in spaceflight pharmacology with insufficient in-flight data to inform future planning. This effort directly addressed in-mission medication use and also informed open questions regarding spaceflight-associated changes in pharmacokinetics (PK) and/or pharmacodynamics (PD).METHODS: An iOS application was designed to collect medication use information relevant for research from volunteer astronaut crewmembers: medication name, dose, dosing frequency, indication, perceived efficacy, and side effects. Leveraging the limited medication choices aboard allowed a streamlined questionnaire. There were 24 subjects approved for participation.RESULTS: Six crewmembers completed flight data collection and five completed ground data collection before NASA’s early study discontinuation. There were 5766 medication use entries, averaging 20.6 ± 8.4 entries per subject per flight week. Types of medications and their indications were similar to previous reports, with sleep disturbances and muscle/joint pain as primary drivers. Two subjects treated prolonged skin problems. Subjects also used the application in unanticipated ways: to note drug tolerance testing or medication holiday per research protocols, and to share data with flight surgeons. Subjects also provided usability feedback on application design and implementation.DISCUSSION: The volume of data collected (20.6 ± 8.4 entries per subject per flight week) is much greater than was collected previously (<12 per person per entire mission), despite user criticisms regarding app usability. It seems likely that improvements in a software-based questionnaire application could result in a robust data collection tool that astronauts find more acceptable, while simultaneously providing researchers and clinicians with useful data.Wotring VE, Smith LK. Dose tracker application for collecting medication use data from International Space Station crew. Aerosp Med Hum Perform. 2020; 91(1):41–45.



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