High-Frequency Ultrasound Assessment of Skin and Oral Mucosa in Metabolic Syndrome Patients—A Cross-Sectional Study

Background: Exogenous factors (such as sun exposure, smoking habits, and diet) and endogenous (inflammatory status, general diseases) have a direct influence on skin and soft tissue characteristics. The study’s objective was to assess the impact of metabolic syndrome (MS) on characteristics of skin layers in sun-exposed and non-exposed maxillofacial tissues evaluated by high-frequency ultrasound (HFU), as a potential diagnosis and monitoring tool for the aging process. Material and methods: The present study included 102 subjects (24 with MS; 78 without MS). Anthropometric parameters and disease history were recorded, and blood samples were harvested in order to assess biochemical parameters of MS. Sun-exposed skin (zygomatic region) and non-exposed oral mucosa of the lower lip were assessed using HFU (DUB® cutis, Taberna Pro Medicum) with a 22 MHz probe. Results: Patients with cardiac disease had significantly lower values for epidermis density (p = 0.002). Gender was independently linked to the aged dermis depth (p < 0.001), aged dermis no. of px (pixels) (p < 0.001), dermis depth (p < 0.001), dermis no. of px (p < 0.001), and subcutaneous tissue density (p < 0.001). Patients with MS had thinner epidermis (p = 0.008) and thinner aged dermis (p = 0.037) when compared to non-MS subjects. Conclusion: Patients with MS had thinner epidermis and a lower epidermis number of pixels in sun-exposed skin. Women had lower epidermis density and thicker dermis in sun-exposed skin. Our study showed that HFU, as a non-invasive investigation approach, is useful to diagnose and monitor the aging process in skin and oral mucosa, correlated with skin phenotype pathological conditions.

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Changes in the microcirculation of the oral mucosa in post-COVID-19 patients not receiving anti-coagulant therapy

Regional blood circulation and microcirculation ◽

10.24884/1682-6655-2021-20-4-95-100 ◽

2022 ◽

Vol 20 (4) ◽

pp. 95-100

Author(s):

M. V. Chubarnova ◽

A. B. Davydov ◽

V. A. Esin ◽

O. B. Davydova ◽

I. O. Kostin

Keyword(s):

Blood Flow ◽

Oral Mucosa ◽

High Frequency ◽

Control Group ◽

High Frequency Ultrasound ◽

Flow Rates ◽

Mean Values ◽

Coronavirus Infection ◽

The Mean ◽

Frequency Ultrasound

Introduction. The outbreak of a new coronavirus infection has become a challenge for the global health system. The COVID-19 infection is directly related to various disorders of the cardiovascular system, including the microcirculatory bed, caused by thrombotic events and deteriorations of blood rheology. Aims. The paper reports on the results of a study of Doppler sonographic parameters changes in patients with a novel coronavirus infection over the past 6 months. Materials and methods. We assessed the oral mucosa microcirculation in three segments using the high-frequency ultrasound dopple-rography. Results. We recorded the linear and volumetric blood flow rates and the Gosling and Purselo indexes in the course of our work. When comparing the obtained average statistical parameters of blood flow velocity, the linear and volumetric blood flow rates in patients of both groups were found to be lain in the same range and the mean values of Vas, Vam, Qas were equal. The mean values of the Purselo resistance index were closer to 1,0 in patients with COVID-19, and the values of the Gosling pulsation index (PI) were on average 53.3 % higher than in the control group. Conclusion. We evaluated the screening capabilities and potential of high-frequency ultrasound dopplerography for use in patients of different age groups and different somatic status.

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COMBINATION OF HIGH-FREQUENCY ULTRASOUND AND ECHO-TRACKING TECHNIQUE FOR EVALUATING THE IMPACT OF BLOOD LIPID ON CAROTID OF RHEUMATOID ARTHRITIS PATIENTS

Heart ◽

10.1136/heartjnl-2012-302920ad.34 ◽

2012 ◽

Vol 98 (Suppl 2) ◽

pp. E303.2-E303

Author(s):

Wang Ping ◽

Zhang Er Hong ◽

Wang Xiao Li ◽

Li Guang-Xia ◽

Wang Ping

Keyword(s):

Rheumatoid Arthritis ◽

High Frequency ◽

Blood Lipid ◽

High Frequency Ultrasound ◽

Tracking Technique ◽

Echo Tracking ◽

The Impact ◽

Frequency Ultrasound

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Discovering a new anatomy: exploration of oral mucosa with ultra-high frequency ultrasound

Dentomaxillofacial Radiology ◽

10.1259/dmfr.20190318 ◽

2020 ◽

Vol 49 (7) ◽

pp. 20190318 ◽

Cited By ~ 2

Author(s):

Rossana Izzetti ◽

Saverio Vitali ◽

Giacomo Aringhieri ◽

Teresa Oranges ◽

Valentina Dini ◽

...

Keyword(s):

Oral Mucosa ◽

Clinical Examination ◽

High Frequency ◽

Diagnostic Technique ◽

High Frequency Ultrasound ◽

Image Description ◽

Ultra High Frequency ◽

Normal Oral Mucosa ◽

Additional Information ◽

Frequency Ultrasound

Objectives: Ultra-high frequency ultrasound (UHFUS) is a recently developed diagnostic technique involving the use of ultrasound frequencies up to 70 MHz, allowing to obtain 30 µm resolution of targets located within 1 cm from the surface. Oral mucosa can be affected by diverse pathological conditions, which are currently investigated by means of clinical examination. In this scenario, intraoral UHFUS can provide additional information and support clinical assessment of oral mucosa. In this preliminary study, typical features of normal oral mucosa are described, in order to set a benchmark for the future identification of oral soft tissue alterations. Methods: Twenty healthy subjects (10 males and 10 females, mean age 30 years) were enrolled and underwent intraoral UHFUS examination. In all the subjects, tongue, buccal mucosa, gingiva, lip mucosa, and palate were scanned, and images acquired. Intraoral UHFUS scan included Brightness-mode and Doppler mode acquisitions performed with a standardized protocol. UHFUS images were postprocessed and analyzed using a dedicated software. UHFUS-based biomarkers (epithelial thickness, echogenicity, and vascularization) were employed for image description. Results: Normal oral anatomy of the different sites analyzed was described. For all the sites, UHFUS biomarkers were characterized, and information on typical aspect of oral mucosa was retrieved. Conclusions: In this explorative study, we suggest a potential role for intraoral UHFUS in the study of oral mucosa, giving insights into the possibility to improve the assessment, diagnosis, and management of the conditions involving oral mucosa. UHFUS seems a promising tool, which could potentially support clinical examination in daily oral medicine practice.

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Multicriteria Optimization Model for the Study of the Efficacy of Skin Antiaging Therapy

Computational and Mathematical Methods in Medicine ◽

10.1155/2012/103919 ◽

2012 ◽

Vol 2012 ◽

pp. 1-6

Author(s):

Maria Crişan ◽

Guido Cappare ◽

Luciana Neamţiu ◽

Ioana Chiorean ◽

Liana Lupşa ◽

...

Keyword(s):

Quality Of Life ◽

Optimization Model ◽

Multicriteria Optimization ◽

High Frequency ◽

Point Of View ◽

High Frequency Ultrasound ◽

Medical Index ◽

The Impact ◽

Frequency Ultrasound

The evolution of the cutaneous structure after topical treatment with P63 antiaging complex, assessed with high frequency ultrasound, is studied by means of multicriteria optimization model. Due to the fact that the impact of the treatment may influence the quality of life, a medical index which measures, from this point of view, the efficacy of the treatment is given, also taking into account medical and economical aspects.

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