scholarly journals The Role of CEUS in the Evaluation of Thyroid Cancer: From Diagnosis to Local Staging

2021 ◽  
Vol 10 (19) ◽  
pp. 4559
Author(s):  
Salvatore Sorrenti ◽  
Vincenzo Dolcetti ◽  
Daniele Fresilli ◽  
Giovanni Del Gaudio ◽  
Patrizia Pacini ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Lymph Node ◽  
Thyroid Nodule ◽  
Lymph Node Involvement ◽  
Research Field ◽  
Invasive Treatment ◽  
Local Staging ◽  
Node Involvement

Ultrasound often represents the first diagnostic step for thyroid nodule evaluation in clinical practice, but baseline US alone is not always effective enough to achieve thyroid nodule characterization. In the last decades new ultrasound techniques, such as CEUS, have been introduced to evaluate thyroid parenchyma as recommended by EFSUMB guidelines, for use in clinical research field, although its role is not yet clear. Several papers show the potential utility of CEUS in the differential diagnosis of benign and malignant thyroid nodules and in the analysis of lymph node involvement in neoplastic pathology. Therefore, we carried out an evaluation of the literature concerning the role of CEUS in three specific areas: the characterization of the thyroid nodule, the evaluation of minimally invasive treatment and loco-regional staging of the lymph node in proven thyroid cancer. According to evidence reported, CEUS can also play an operative role in nodular thyroid pathology as it is able to guide ablation procedures on thyroid nodule and metastatic lymph nodes, to assess the radicality of surgery, to evaluate disease relapse at the level of the margins of ablated regions and to monitor the clinical evolution of necrotic areas in immediate post-treatment setting.

scholarly journals PD-0461: Characterization of nodal metastases in prostate cancer patients at high risk for lymph node involvement

2013 ◽  
Vol 106 ◽  
pp. S179
Author(s):  
S. Isebaert ◽  
E. Lerut ◽  
L. Van den Bergh ◽  
S. Joniau ◽  
R. Oyen ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Lymph Node ◽  
High Risk ◽  
Cancer Patients ◽  
Lymph Node Involvement ◽  
Nodal Metastases ◽  
Node Involvement

scholarly journals Quality of Life and Anxiety in Adolescents with Differentiated Thyroid Cancer

2012 ◽  
Vol 97 (10) ◽  
pp. E1933-E1937 ◽  
Author(s):  
Asaf Oren ◽  
Melissa Anne Benoit ◽  
Anne Murphy ◽  
Fiona Schulte ◽  
Jill Hamilton
Keyword(s):  
Quality Of Life ◽  
Thyroid Cancer ◽  
Lymph Node ◽  
Differentiated Thyroid Cancer ◽  
Lymph Node Involvement ◽  
Autoimmune Hypothyroidism ◽  
Control Subjects ◽  
Node Involvement ◽  
Anxiety Levels

Abstract Context: Adolescents with differentiated thyroid cancer (DTC) require lifelong monitoring with a high possibility of reoperation or radioactive iodine. Although adult DTC survivors have similar or slightly worse quality of life (QOL), this has not been evaluated in the pediatric population. Objective: Our objective was to compare QOL and anxiety in adolescents with DTC to patients with acquired autoimmune hypothyroidism. Design, Setting, and Patients: In this cross-sectional pilot study, three validated questionnaires were administered to 16 adolescents with DTC and 16 controls for assessment of QOL and anxiety levels. These included teen and parent PedsQL, Multidimensional Anxiety Scale for Children, and Coddington Life Events Scales for Adolescents. The contribution of age, time since diagnosis, and biochemical variables were compared with the outcome measures. Results: There were 16 DTC patients (seven males); 13 had papillary carcinoma, one had follicular carcinoma, and two had mixed type. At diagnosis, five DTC patients had lymph node involvement and two had lung metastases, although at time of assessment, only one DTC patient had lymph node involvement. DTC patients were older than control subjects (P = 0.004) and had lower TSH levels than control subjects at time of assessment (P = 0.013). QOL and anxiety levels did not differ between DTC patients compared with control subjects and with previously reported scores in a healthy cohort. QOL and anxiety level parameters were not influenced by age, time since diagnosis, or free T4 levels measured at the time of assessment. Conclusions: Adolescents with DTC have similar QOL and anxiety levels compared with autoimmune hypothyroidism patients and with a healthy normative population.

Role of prostate dose escalation in patients with greater than 15% risk of pelvic lymph node involvement

2005 ◽  
Vol 61 (3) ◽  
pp. 695-701 ◽  
Author(s):  
Rojymon Jacob ◽  
Alexandra L. Hanlon ◽  
Eric M. Horwitz ◽  
Benjamin Movsas ◽  
Robert G. Uzzo ◽  
...  
Keyword(s):  
Lymph Node ◽  
Dose Escalation ◽  
Lymph Node Involvement ◽  
Pelvic Lymph Node ◽  
Node Involvement ◽  
Pelvic Lymph Node Involvement

Changing trends of incidence and prognosis of thyroid carcinoma

2019 ◽  
Vol 58 (02) ◽  
pp. 86-92 ◽  
Author(s):  
Jamshid Farahati ◽  
Uwe Mäder ◽  
Elena Gilman ◽  
Rainer Görges ◽  
Ines Maric ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Lymph Node ◽  
Distant Metastases ◽  
Tumor Stage ◽  
Lymph Node Involvement ◽  
Population Based ◽  
Management Algorithm ◽  
Node Involvement ◽  
T1 And T2 ◽  
Lower Franconia

Abstract Aim to evaluate the time trend of epidemiology of follicular cell derived thyroid cancer (TC) based on data from a well documented cancer registry. Methods Population based data on TC from Lower Franconia (LF), Germany, within 1981 and 2015 were analysed to estimate the regional epidemiology of TC. The incidence was assessed in 5-year-intervals for gender, histology, and tumor stage. Results Incidence of TC solely attributable to papillary TC (PTC) doubled mainly in T1- and T2-stages within the evaluation period from 4.5 to 8.7/100.000/y in females and 1.7 to 4.1/100.000/y in males. There was no significant change of follicular TC (FTC), whereas anaplastic TC (ATC) decreased in the same interval. The number of lymph-node metastases and T3-cases increased, while the frequency of T4-stage and distant metastases decreased. Increased incidences of T1- and T2-stages suggest an over-diagnosis. In contrast, increasing number of tumors at T3-stage and with lymph node involvement contradict the over-diagnosis as the only reason for rising incidence. Declining of T4-stages in spite of increasing of T3-stages and N1-cases indicates the value of timely detection and treatment of TC. In accordance, reduced incidence of advanced cancers with M1-stage and ATC cases promote our current management of TC. Conclusion Timely diagnosis and adequate risk-adopted treatment of thyroid cancer reduce the frequency of high-risk cases with distant metastases and the possible protracted dedifferentiation of TC to anaplastic features. Our analyses support the management algorithm in thyroid cancer according to the recent guidelines of German Nuclear Medicine Society.

scholarly journals Cancers of the Appendix: Review of the Literatures

ISRN Oncology ◽  
2011 ◽  
Vol 2011 ◽  
pp. 1-6 ◽  
Author(s):  
Carl Ruoff ◽  
Louay Hanna ◽  
Wanqing Zhi ◽  
Ghulamullah Shahzad ◽  
Vladimir Gotlieb ◽  
...  
Keyword(s):  
Lymph Node ◽  
Carcinoid Syndrome ◽  
Randomized Trials ◽  
Surgical Intervention ◽  
Somatostatin Analogues ◽  
Lymph Node Involvement ◽  
Right Hemicolectomy ◽  
Peritoneal Seeding ◽  
Node Involvement

Cancers of the appendix are rare. Most of them are found accidentally on appendectomies performed for appendicitis. When reviewed, majority of the tumors were carcinoid, adenoma, and lymphoma. Adenocarcinomas of appendix are only 0.08% of all cancers and the treatment remains controversial. Here we are reporting a 46-year-old male presented with symptoms of appendicitis, diagnosed with adenocarcinoma of the appendix. The patient was treated with appendectomy and refused further surgical intervention to complete hemicolectomy. Up to date, he remains asymptomatic. We performed literature review of the tumors of the appendix. Most of the benign conditions are treated with surgery alone. Lymphomas require CHOP-like chemotherapy and carcinoid syndrome treatment with somatostatin analogues. It is generally recommended that right hemicolectomy is the preferred treatment for adenocarcinoma of appendix. The role of chemotherapy is unclear due to lacking randomized trials but seems to be accepted if there is lymph node involvement or peritoneal seeding.

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