scholarly journals Modeling the Longitudinal Effects of Insight on Depression, Quality of Life and Suicidality in Schizophrenia Spectrum Disorders: Results from the FACE-SZ Cohort

2019 ◽  
Vol 8 (8) ◽  
pp. 1196 ◽  
Author(s):  
Mickaël Ehrminger ◽  
Mathieu Urbach ◽  
Christine Passerieux ◽  
Bruno Aouizerate ◽  
Fabrice Berna ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Structural Equation ◽  
Negative Symptoms ◽  
Equation Modeling ◽  
Schizophrenia Spectrum Disorders ◽  
Targeted Interventions ◽  
Schizophrenia Spectrum ◽  
Baseline Levels ◽  
Spectrum Disorders

Background: Up to half of the patients with schizophrenia attempt suicide during their lifetime. Better insight is associated with better functioning but also with increased suicidality. The direction of the relationship between insight and suicidality is not clear, hence we aimed to provide new elements using structural equation modeling. Methods: Insight, quality of life (QoL), depression, and suicidality were measured at baseline and at 12 months in individuals with schizophrenia spectrum disorders. The relationships between these variables were investigated by latent difference score models, controlling for chlorpromazine doses, positive and negative symptoms, and general psychopathology. Results: 738 patients were included, and 370 completed the study. Baseline levels of insight predicted changes in suicidality, whereas baseline levels of suicidality did not predict changes in insight, suggesting that better insight underlies suicidality and predicts its worsening. Our results suggest this temporal sequence: better insight → worse QoL → increased depression → increased suicidality, while insight also affects the three variables in parallel. Conclusion: Better insight predicts a worsening of QoL, depression and suicidality. These findings contribute to our global understanding of the longitudinal influence of insight on suicidality. We advocate that insight-targeted interventions should not be proposed without the monitoring of depression and suicide prevention.

scholarly journals Psychological wellness, yoga and quality of life in patients affected by schizophrenia spectrum disorders: A pilot study

2019 ◽  
Vol 11 (1) ◽  
pp. 22-25
Author(s):  
Pasquale Caponnetto ◽  
Roberta Auditore ◽  
Marilena Maglia ◽  
Stefano Pipitone ◽  
Lucio Inguscio
Keyword(s):  
Quality Of Life ◽  
Negative Symptoms ◽  
Clinical Psychologist ◽  
Control Group ◽  
Schizophrenia Spectrum Disorders ◽  
Neurocognitive Deficits ◽  
Schizophrenia Spectrum ◽  
Significant Difference ◽  
Spectrum Disorders

Schizophrenia is a serious psychiatric disorder characterized by positive symptoms, negative symptoms and neurocognitive deficits. The aim of this study was to estimate relationships between wellness, yoga and quality of life in patients affected by schizophrenia spectrum disorders. Participants were 30 patients with a diagnosis of schizophrenia in care at the Rehabilitative Psychiatry and Research Villa Chiara Clinic in Mascalucia (Catania, Italy), after that randomly assigned to two groups. The first group followed the experimental treatment with sets of yoga exercises conducted by a yoga trainer and a psychiatrist or a clinical psychologist expert in yoga, while a second control group was treated with usual care. The results revealed a significant difference, before and after treatment, between the experimental group and the control group in quality of life.

scholarly journals Psychological wellness, yoga and quality of life in patients affected by schizophrenia spectrum disorders: A pilot study

2019 ◽  
Vol 11 (1) ◽  
Author(s):  
Pasquale Caponnetto ◽  
Roberta Auditore ◽  
Marilena Maglia ◽  
Stefano Pipitone ◽  
Lucio Inguscio
Keyword(s):  
Quality Of Life ◽  
Negative Symptoms ◽  
Clinical Psychologist ◽  
Control Group ◽  
Schizophrenia Spectrum Disorders ◽  
Neurocognitive Deficits ◽  
Schizophrenia Spectrum ◽  
Significant Difference ◽  
Spectrum Disorders

Schizophrenia is a serious psychiatric disorder characterized by positive symptoms, negative symptoms and neurocognitive deficits. The aim of this study was to estimate relationships between wellness, yoga and quality of life in patients affected by schizophrenia spectrum disorders. Participants were 30 patients with a diagnosis of schizophrenia in care at the Rehabilitative Psychiatry and Research Villa Chiara Clinic in Mascalucia (Catania, Italy), after that randomly assigned to two groups. The first group followed the experimental treatment with sets of yoga exercises conducted by a yoga trainer and a psychiatrist or a clinical psychologist expert in yoga, while a second control group was treated with usual care. The results revealed a significant difference, before and after treatment, between the experimental group and the control group in quality of life.

Self-stigma and quality of life in Psychopharmacs treated outpatients with schizophrenia and related disorders - A cross-sectional study

2016 ◽  
Vol 33 (S1) ◽  
pp. s253-s254
Author(s):  
M. Holubova ◽  
J. Prasko ◽  
K. Latalova ◽  
M. Ociskova ◽  
A. Grambal ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Negative Impact ◽  
Demographic Data ◽  
The Self ◽  
Control Group ◽  
Healthy Controls ◽  
Schizophrenia Spectrum Disorders ◽  
Schizophrenia Spectrum ◽  
Spectrum Disorders

IntroductionSelf-stigma is a maladaptive psychosocial phenomenon that can disturb self-image and quality of life in psychiatric outpatients and may lead to dysphoria, social isolation and reduced adherence to treatment.ObjectivesSelf-stigma and QoL could be reflected as important factors for patients, who suffer from schizophrenia spectrum disorders, their caregivers and mental health specialists. Focus on reducing the self-stigma in supportive and educational therapy could be an important factor in promoting a higher QoL.AimsCurrent research moved attention to the relationship between demographic data, the severity of symptoms, self-stigma and quality of life in schizophrenic outpatients compared to the QoL in healthy controls.MethodsPatients who met ICD-10 criteria for schizophrenia spectrum disorder were recruited in the study. The Quality of Life Satisfaction and Enjoyment questionnaire (Q-LES-Q), Internalized Stigma of Mental Illness (ISMI) and severity of the disorder measured by objective and subjective Clinical Global Impression severity scales (CGI) were assessed.ResultsOne hundred and nine psychotic patients and 91 healthy controls participated in the study. Compared to the control group, there was a lower QoL and a higher score of self-stigma in psychotic patients. We found the correlation between the self-stigma, duration of disorder and QoL. The level of self-stigma correlated positively with total symptom severity score and negatively with the QoL. Stepwise regression analysis revealed that the objective severity and self-stigma score were significantly associated with the quality of life (Figure 2 and 3, Fig. 1).ConclusionsOur study suggests a negative impact of self-stigma level on the quality of life in patients suffering from schizophrenia spectrum disorders.Disclosure of interestThe authors have not supplied their declaration of competing interest.

Quality of life in schizophrenia spectrum disorders: Associations with insight and psychopathology

2015 ◽  
Vol 225 (3) ◽  
pp. 695-701 ◽  
Author(s):  
Maria Margariti ◽  
Dimitris Ploumpidis ◽  
Marina Economou ◽  
George N. Christodoulou ◽  
George N. Papadimitriou
Keyword(s):  
Quality Of Life ◽  
Schizophrenia Spectrum Disorders ◽  
Schizophrenia Spectrum ◽  
Spectrum Disorders

scholarly journals Childhood temperament is associated with distress, anxiety and reduced quality of life in schizophrenia spectrum disorders

2019 ◽  
Vol 275 ◽  
pp. 196-203 ◽  
Author(s):  
Brandee Feola ◽  
Kristan Armstrong ◽  
Neil D. Woodward ◽  
Stephan Heckers ◽  
Jennifer Urbano Blackford
Keyword(s):  
Quality Of Life ◽  
Schizophrenia Spectrum Disorders ◽  
Schizophrenia Spectrum ◽  
Spectrum Disorders

scholarly journals Factorial structure of the Manchester Short Assessment of Quality of Life in patients with schizophrenia-spectrum disorders

2019 ◽  
Vol 29 (3) ◽  
pp. 833-841
Author(s):  
Eleni Petkari ◽  
Domenico Giacco ◽  
Stefan Priebe
Keyword(s):  
Quality Of Life ◽  
Living Environment ◽  
Factorial Structure ◽  
Schizophrenia Spectrum Disorders ◽  
Schizophrenia Spectrum ◽  
Calibration Sample ◽  
Two Factors ◽  
Health Related ◽  
Spectrum Disorders

Abstract Purpose Subjective quality of life is a central patient-reported outcome in schizophrenia-spectrum disorders. The Manchester Short Assessment of Quality of Life (MANSA) is an established and widely used instrument for its assessment. The present study is a secondary analysis of large schizophrenia studies and aims to establish the factorial structure of the MANSA with a rigorous two-step methodology. Methods A sample of 3120 patients was randomly split into two datasets; the first includes two thirds of the patients and serves as the calibration sample (N = 2071) and the second includes one third of them and serves as the validation sample (N = 1049). We performed an exploratory factor analysis with the calibration sample followed by a confirmatory factor analysis with the validation sample. Results Our results for both samples revealed a model with adequate fit comprising two factors. The first factor encompasses eight items measuring satisfaction with a variety of life and health-related aspects of quality of life, whereas the second consists of four items assessing satisfaction with living environment comprising living alone or with others, accommodation, family, and safety. These two factors correlate in a different way with socio-demographic characteristics such as age and living conditions. Conclusions Future trials and service evaluation projects using the MANSA to measure quality of life should take into account that satisfaction with living environment may be distinct from satisfaction with other life and health-related aspects of quality of life.

scholarly journals M122. DEPRESSION IN SCHIZOPHRENIA SPECTRUM DISORDERS: LONGITUDINAL COURSE AND THE RELATIONSHIP WITH OTHER CLINICAL PARAMETERS AND QUALITY OF LIFE

2020 ◽  
Vol 46 (Supplement_1) ◽  
pp. S181-S182
Author(s):  
Lebogang Phahladira ◽  
Laila Asmal ◽  
Bonginkosi Chiliza ◽  
Hilmar Luckhoff ◽  
Stefan du Plessis ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Depressive Symptoms ◽  
First Episode ◽  
Clinical Parameters ◽  
Schizophrenia Spectrum Disorders ◽  
Schizophrenia Spectrum ◽  
Spectrum Disorders ◽  
First Episode Schizophrenia ◽  
The Relationship

Abstract Background The relationship between schizophrenia and depression is complex. Longitudinal studies on the course of depression in first episode schizophrenia populations are scarce and there are conflicting results on the predictive value of some baseline measures. Methods We conducted an open label longitudinal cohort study which included 126 patients with first-episode schizophrenia spectrum disorders treated with long-acting antipsychotic medication over 24 months. Depression was assessed at three monthly intervals using the Calgary Depression Scale for Schizophrenia. Changes in depression over time were assessed using the linear mixed-effect models for continuous repeated measures. The relationship between depression and other clinical parameters was assessed with regression models. Results Depressive symptoms were most prominent at baseline and showed highly significant reductions in the first three months (p<0.0001). Majority of the patients with depression improved with antipsychotic medication alone and we found associations between depressive symptoms with insight and poorer quality of life, however only illness awareness (p=0.0035) was the only significant predictor on depression in our regression analysis. There were a few differences between patients who experienced depression during the acute phase of treatment and those in the post-acute phase. Discussion Our findings suggest that depression in schizophrenia is common and generally responds well to treatment. The relationship between depression and insight has implications for further treatment considerations

Comparison of self-stigma and quality of life in depressive disorder and schizophrenia – a cross-sectional study

2017 ◽  
Vol 41 (S1) ◽  
pp. S356-S356
Author(s):  
M. Holubova ◽  
J. Prasko ◽  
S. Matousek ◽  
K. Latalova ◽  
M. Marackova ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Depressive Disorders ◽  
Cross Sectional Study ◽  
Internalized Stigma ◽  
Schizophrenia Spectrum Disorders ◽  
Sectional Study ◽  
Cross Sectional ◽  
Schizophrenia Spectrum ◽  
Spectrum Disorders

BackgroundThe views of one's self-stigma and quality of life in patients with schizophrenia and depressive disorders are significant subjective notions, both being proven to affect patient's functioning in life. The objective of this research was to find out the quality of life and self-stigma in connection with demographic factors and compare the two groups of patients in those variables.MethodIn a cross-sectional study, the outpatients with the schizophrenia spectrum disorders and depressive disorders completed the quality of life satisfaction and enjoyment questionnaire, the internalized stigma of mental illness scale and a demographic questionnaire during a routine psychiatric control. Furthermore, both patients and their psychiatrists evaluated the severity of the disorder by clinical global impression-severity scale.ResultsThe quality of life of patients with depression or schizophrenia spectrum disorders did not significantly differ between the two groups. In both groups, unemployment was perceived to be a significant factor decreasing the quality of life. Self-stigma was detected to be higher in patients with schizophrenia as compared to the depressive patients. A strong correlation was found between the two scales, meaning that those with higher levels of self-stigmatization were less prone to see their life as fulfilling and joyful.ConclusionsThe present study shows that the degree of the internalized stigma can be an important aspect linked to the quality of life irrespective of the diagnostic category.Disclosure of interestThe authors have not supplied their declaration of competing interest.

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