scholarly journals Treatment of Intrabony Defects with a Combination of Hyaluronic Acid and Deproteinized Porcine Bone Mineral

Materials ◽  
2021 ◽  
Vol 14 (22) ◽  
pp. 6795
Author(s):  
Darko Božić ◽  
Ivan Ćatović ◽  
Ana Badovinac ◽  
Larisa Musić ◽  
Matej Par ◽  
...  

Background: this study evaluates the clinical outcomes of a novel approach in treating deep intrabony defects utilizing papilla preservation techniques with a combination of hyaluronic acid (HA) and deproteinized porcine bone mineral. Methods: 23 patients with 27 intrabony defects were treated with a combination of HA and deproteinized porcine bone mineral. Clinical attachment level (CAL), pocket probing depth (PPD), gingival recession (REC) were recorded at baseline and 6 months after the surgery. Results: At 6 months, there was a significant CAL gain of 3.65 ± 1.67 mm (p < 0.001) with a PPD reduction of 4.54 ± 1.65 mm (p < 0.001), which was associated with an increase in gingival recession (0.89 ± 0.59 mm, p < 0.001). The percentage of pocket resolution based on a PPD ≤4 mm was 92.6% and the failure rate based on a PPD of 5 mm was 7.4%. Conclusions: the present findings indicate that applying a combined HA and xenograft approach in deep intrabony defects provides clinically relevant CAL gains and PPD reductions compared to baseline values and is a valid new approach in treating intrabony defects.

2010 ◽  
Vol 53 (4) ◽  
pp. 229-234 ◽  
Author(s):  
Sujith Sukumar ◽  
Ivo Dřízhal ◽  
Josef Bukač ◽  
Vladimíra Paulusová ◽  
Shriharsha Pilathadka

Alloplastic bone graft materials are widely been used in combination with barrier membranes to achieve guided tissue regeneration in the treatment of periodontal intrabony defects. This study was designed to evaluate the clinical outcome of a composite material, beta tricalcium phosphate in combination with calcium sulphate in the treatment of periodontal intrabony defects. The combination of these materials is believed to aid in guided tissue regeneration owing to their properties. Thirty nine intrabony defects in 21 patients were treated with Fortoss® Vital (Biocomposites, Staffordshire, UK). Clinical parameters were evaluated including changes in probing depth, clinical attachment level/loss and gingival recession at baseline and one year postoperatively. The mean differences in measurements between the baseline and one year postoperatively are a reduction of 1.98±1.16 mm (p=0.000) in case of probing depth and a gain of 1.68±1.12 mm (p=0.000) in clinical attachment level and an increase of 0.31±0.67 mm (p=0.009) in gingival recession measurements. The study results show that the treatment with a combination of beta tricalcium phosphate and calcium sulphate led to a significantly favorable clinical improvement in periodontal intrabony defects one year postoperatively.


2006 ◽  
Vol 309-311 ◽  
pp. 1397-1400
Author(s):  
Ui Won Jung ◽  
S.J. Chang ◽  
Seong Ho Choi ◽  
C.S. Kim ◽  
Jung Kiu Chai

This study evaluated the effects of mixture of fibrin-fibronectin sealant system(FFSS) and calcium carbonate(CC) in periodontal intrabony defects. Thirty six sites with two or three wall intrabony defect were used. 14 defects treated with periodontal flap surgery were assigned as the control group. 11 defects treated with CC implantation were designed as experimental group 1 and 11 defects, treated with CC and FFSS implantation as experimental group 2. The control and experimental groups all achieved statistically significant improvements in probing depth and clinical attachment level from the baseline (P<0.01). In mean postsurgery probing depth and gingival recession reduction, there were no statiscally significant differences between the experimental groups and the controls. However, mean postsurgery clinical attachment levels of both experimental groups improved significantly more than that of the controls. As a result, we suggest that mixture of FFSS and CC can be used effectively in intrabony defect as osteoconductive materials.


2011 ◽  
Vol 54 (1) ◽  
pp. 13-20 ◽  
Author(s):  
Sujith Sukumar ◽  
Ivo Dřízhal ◽  
Vladimíra Paulusová ◽  
Josef Bukač

The study was designed to evaluate the clinical outcome of a composite material, beta-tricalcium phosphate in combination with calcium sulphate, in the treatment of periodontal intrabony defects. The combination of these materials is believed to aid in guided tissue regeneration owing to their properties. A total of 47 teeth with intrabony defects in 26 periodontitis patients were treated with Fortoss® Vital (Biocomposites, Staffordshire, UK). Clinical parameters were evaluated which included changes in probing depth, clinical attachment level/loss and gingival recession at the baseline and 2 years postoperatively. The mean differences in measurements between the baseline and 2 years postoperatively were a reduction of 2.07±1.14 mm (p=0.000) in case of probing depth and a gain of 1.93±1.36 mm (p=0.000) in clinical attachment level; but an increase of 0.14±0.73 mm (p=0.571) in gingival recession. The study results show that the treatment with a combination of beta tricalcium phosphate and calcium sulphate led to a significantly favorable clinical improvement in periodontal intrabony defects 2 years after the surgery.


2016 ◽  
Vol 73 (4) ◽  
pp. 325
Author(s):  
Gabriela Alessandra Da C. Galhardo Camargo ◽  
Mariana Gouvea Latini Abreu ◽  
Renata Dos Santos ◽  
Marcio Alves Crespo ◽  
Leticia De Faria Wenderoscky

Objective: the aim of this study was to evaluate, through literature review, clinical aspects (plaque index, gingival index, probing depth, gingival recession and clinical attachment level) and microbiological (qualitative and quantitative presence of periodontal pathogens) in smokers patients and the response to periodontal therapy. Material and Methods: it was selected scientific articles published between the years 1978 and 2014. We were selected scientific articles from MEDLINE, PUBMED and LILACS databases. Results: there are controversies between tobacco and clinical and microbiological parameters. Conclusion: based on the evaluated studies we can conclude that there are significant clinical and microbiological differences in smoking patients and impaired response to periodontal therapy.


2003 ◽  
Vol 50 (1) ◽  
pp. 18-23 ◽  
Author(s):  
Sasa Jankovic ◽  
Bozidar Dimitrijevic

This study was designed to compare the effectiveness and predictability of GTR and connective tissue graft in the treatment of gingival recession. 15 recessions Miller class II and III were treated with bioabsorbable barrier and coronally advanced flap. The same number of defects was treated with connective tissue graft in combination with coronally advanced flap. Clinical recordings included hygiene standards and recession depth (RD) probing depth (PD), clinical attachment level (CAL) and keratinized tissue width (KT) Mean (RD) was statistically significant decreased from 5,47mm presurgery to 0.73mm with GTR (87,76%) and from 5,93mm to 0.60 with CTG (89.9%). Prevalence of complete root coverage was 40% for the GTR and 46,66% for CTG group. No statistically significant differences between treatment groups were observed in this study Treatment of gingival recessions with CTG and GTR present effective and highly predictable mucogingival plastic surgical procedures.


2012 ◽  
Vol 10 (1) ◽  
pp. 7-10
Author(s):  
KV Satyanarayana ◽  
BR Anuradha ◽  
G Srikanth ◽  
P Mohan Chandra ◽  
T Anupama ◽  
...  

Background Aggressive periodontitis is a specific type of periodontitis with clearly identifiable clinical characteristics such as “rapid attachment loss, bone destruction” and “familial aggregation”. Regeneration of mineralized tissues affected by aggressive periodontitis comprises a major scientific and clinical challenge. In recent years some evidence has been provided that bioactive glass is also capable of supporting the regenerative healing of periodontal lesions. Objective The aim of this clinical and radiological prospective study was to evaluate the efficacy of bioactive glass in the treatment of intra-bony defects in patients with localized aggressive periodontitis. Methods Twelve localized aggressive periodontitis patients with bilaterally located three-walled intra-bony defect depth ? 2 mm, preoperative probing depths ? 5 mm were randomly treated either with the bioactive glass or without the bioactive glass. The clinical parameters plaque index, gingival index, probing depth, gingival recession, clinical attachment level, and mobility were recorded prior to surgery as well as 12 months after surgery. Intraoral radiographs were digitized to evaluate the bone defect depth at baseline and 12 months after the surgery. Results After 12 months, a reduction in probing depth of 3.92 + 0.313 mm (P <0.001) and a gain in clinical attachment level of 4.42+0358mm (P <0.001) were registered in the test group. In the control group, a reduction in probing depth of 2.5 +0.230mm (P <0.001) and a gain in clinical attachment level of 2.58 + 0.149 mm (P<0.001) was recorded. Radiographically, the defects were found to be filled by 2.587 + 0.218 mm (P <0.001) in the test group and by 0.1792 + 0.031mm (P <0.001) in the control group. Changes in gingival recession showed no significant differences. . Conclusion Highly significant improvements in the parameters Probing depth, Clinical attachment level, and Bone defect depth were recorded after 12 months, with regenerative material. KATHMANDU UNIVERSITY MEDICAL JOURNAL  VOL.10 | NO. 1 | ISSUE 37 | JAN - MAR 2012 | 11-15 DOI: http://dx.doi.org/10.3126/kumj.v10i1.6906


2021 ◽  
Vol 9 (06) ◽  
pp. 549-558
Author(s):  
Bangaru Mounika ◽  
Ajay Reddy P. ◽  
Sanjay Vasudevan ◽  
Vaishnavi a ◽  
Sunny Rajoria ◽  
...  

Aims and Objectives-The aim of the present study was to evaluate the regenerative potential of synthetic nanocrystalline calcium sulphate bone graft (NANOGENTM) in treatment of intrabony defect both clinically and radiographically. Materials and Methods- Study was conducted in 10 patients with 10 defect sites with probing pocket depth >5mm with radiographs at base line were selected. All the sites with intrabony defects treated with NanogenTM bone graft and follow up was done for 3 months and 6 months respectively. Clinical parameters included in the study are of plaque index, probing depth (PD), clinical attachment level (CAL), Sulcus bleeding index (SBI). Radiographic parameters include bone fill. Results-In the present study, the mean clinical attachment loss, plaque index, probing depth index, sulcus bleeding index at baseline was 9.11±1.054, 1.5278±1.9543, 8.44±1.130, 3.7222±.77504 respectively, reduced to 5.7±1.093,.6389±.37731,3.67±.500,1.2222±.75462 respectively at the end of the 3 months.5.00±.707, .4167±.39528, 2.78±.667, .4167±.46771 respectively at the end of the 6 months. The mean bone fill baseline was 9.11 ± 1.054 mm which was reduced to 5.78 ± 1.093 mm at 3 months and reduced to 5.00 ± 0.707 mm at 6 months, showing a bone fill of 3.933 ± 0.3640 mm by the end of three months and 4.256 ± 0.3678 by the end of six months which were statistically significant (P=0.002). Conclusion- Present study, evidenced that reduction in probing depths, gain in clinical attachment level and bone fill. Improvement of clinical and radiographic parameters at sites treated with NanogenTM.


2008 ◽  
Vol 34 (4) ◽  
pp. 185-189 ◽  
Author(s):  
Rodrigo Tadashi Martines ◽  
Wilson Roberto Sendyk ◽  
Alfredo Gromatzky ◽  
Patricia Ramos Cury

Abstract This study uses a sandblasted/acid-etched implant vs a smooth-surface implant to compare implant mobility and clinical reactions of peri-implant tissues to experimentally induced peri-implantitis in Beagle dogs. The right and left mandibular premolars were extracted from 5 Beagle dogs, and 2 smooth-surface (SS) implants and 2 sandblasted/acid-etched (SLA) implants were placed in each animal. After 120 days, healing abutments were connected. Fifteen days later, the prosthetic abutments were connected, the hygiene regimen was suspended, and peri-implantitis was induced by the insertion of cotton ligatures into the soft tissue around the implants. At baseline and 30, 60, and 90 days later, clinical attachment level (CAL), probing depth (PD), and mobility (MO) were measured. Probing depth increased significantly in the SLA group alone when baseline PD was compared with 30-, 60-, and 90-day evaluations (P &lt; .05). No significant differences were noted between the 2 implant groups (P &gt; .05). The loss in CAL was significant in both groups when the baseline value was compared with 30-, 60-, and 90-day evaluations (P &lt; .02). Comparison between the 2 implant groups revealed a greater loss in CAL in the SLA group at the 90-day evaluation period (P = .04). A significant increase in mobility was seen in both groups when baseline values and 90-day evaluations were compared (P &lt; .04). However, no statistically significant differences were noted between the 2 implant groups (P &gt; .05). Experimentally induced peri-implantitis results in a greater loss of CAL in SLA implants than in SS implants in dogs; however, no differences in mobility or in PD have been noted between the 2 implant groups.


Author(s):  
Anna Simonelli ◽  
Luigi Minenna ◽  
Leonardo Trombelli ◽  
Roberto Farina

Abstract Aim To comparatively evaluate the clinical effectiveness of the single flap approach (SFA) with and without enamel matrix derivative (EMD) in the treatment of supraosseous defects (SDs) associated with deep pockets. Materials and methods Twenty patients, each contributing one SD associated with a deep (≥ 6 mm) pocket and treated with buccal SFA either alone (SFA group; n = 10) or in combination with EMD (SFA+EMD group; n =10), were retrospectively selected. Clinical parameters (probing depth, PD; clinical attachment level, CAL; gingival recession, REC) had been assessed at pre-surgery and 12 months post-surgery. Results Complete wound closure was observed in 70% and 80% of defects treated with SFA and SFA+EMD, respectively. Treatments resulted in a significant PD reduction of 3.1±1.0 mm (p=0.005). In SFA+EMD group, 100% of closed pockets was obtained, while 90% of closed pockets was observed in SFA group. Both treatments resulted in a significant CAL gain of 2.1±0.9 mm and 1.9±1.7 mm in SFA and SFA+EMD group, respectively (p= 0.465). In both groups, REC significantly increased 1.0±1.1 mm in SFA group and 1.1±1.1 mm in SFA+EMD group (p= 0.722). Conclusions Within their limits, the findings of present study suggest that SFA may represent a valuable option for the surgical treatment of SDs associated with deep pockets. EMD did not result in a significant clinical benefit to the procedure. Clinical relevance SFA may represent a valuable option in obtaining pocket closure when treating SDs associated with deep residual pockets.


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