scholarly journals A Systematic Review to Assess the Impact of Hyperbaric Oxygen Therapy on Glycaemia in People with Diabetes Mellitus

Medicina ◽  
2021 ◽  
Vol 57 (10) ◽  
pp. 1134
Author(s):  
Sudhanshu Baitule ◽  
Aaran Patel ◽  
Narasimha Murthy ◽  
Sailesh Sankar ◽  
Ioannis Kyrou ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Systematic Review ◽  
Glycaemic Control ◽  
Hyperbaric Oxygen ◽  
Oxygen Therapy ◽  
Hyperbaric Oxygen Treatment ◽  
Oxygen Treatment ◽  
Diabetic Foot Disease ◽  
Foot Disease ◽  
The Impact

Background and Objectives: Hyperbaric oxygen is a recognised treatment for a range of medical conditions, including treatment of diabetic foot disease. A number of studies have reported an impact of hyperbaric oxygen treatment on glycaemic control in patients undergoing treatment for diabetic foot disease. There has been no systematic review considering the impact of hyperbaric oxygen on glycaemia in people with diabetes. Materials and Methods: A prospectively PROSPERO-registered (PROSPERO registration: CRD42021255528) systematic review of eligible studies published in English in the PUBMED, MEDLINE, and EMBASE databases, based on the following search terms: hyperbaric oxygen therapy, HBO2, hyperbaric oxygenation, glycaemic control, diabetes, diabetes Mellitus, diabetic, HbA1c. Data extraction to pre-determined piloted data collection form, with individual assessment of bias. Results: In total, 10 eligible publications were identified after screening. Of these, six articles reported a statistically significant reduction in blood glucose from hyperbaric oxygen treatment, while two articles reported a statistically significant increase in peripheral insulin sensitivity. Two articles also identified a statistically significant reduction in HbA1c following hyperbaric oxygen treatment. Conclusions: There is emerging evidence suggesting a reduction in glycaemia following hyperbaric oxygen treatment in patients with diabetes mellitus, but the existing studies are in relatively small cohorts and potentially underpowered. Additional large prospective clinical trials are required to understand the precise impact of hyperbaric oxygen treatment on glycaemia for people with diabetes mellitus.

Oxygen treatment of cluster headache: A review

Cephalalgia ◽  
2014 ◽  
Vol 34 (13) ◽  
pp. 1079-1087 ◽  
Author(s):  
Anja S Petersen ◽  
Mads CJ Barloese ◽  
Rigmor H Jensen
Keyword(s):  
Cluster Headache ◽  
Hyperbaric Oxygen ◽  
Oxygen Therapy ◽  
Positive Response ◽  
Low Flow ◽  
Hyperbaric Oxygen Treatment ◽  
Flow Rates ◽  
Oxygen Treatment ◽  
High Flow Oxygen ◽  
Pubmed Search

Purpose Our aim was to review the existing literature to document oxygen’s therapeutic effect on cluster headache. Method A PubMed search resulted in 28 hits, and from these and their references we found in total 11 relevant studies. We included six studies that investigated the efficacy of oxygen treatment. One study is observational and the remaining five are RCTs. Another five studies were on hyperbaric oxygen treatment hereof two case studies. Conclusion Oxygen therapy can be administered at different flow rates. Three studies investigate the effect of low-flow oxygen, 6–7 l/min, and found a positive response in 56%, 75% and 82%, respectively, of the patients. One study investigates high-flow oxygen, 12 l/min, and found efficacy in 78% of attacks. The effect of hyperbaric oxygen therapy has been investigated in a few small studies and there is evidence only for an acute, but not a prophylactic effect. Despite the fact that only a few high-quality RCT studies are available, oxygen treatment is close to an ideal treatment because it is effective and safe. However, sufferers of cluster headache do not always have access to oxygen because of logistic and financial concerns.

scholarly journals The Effects of Ultra-early Hyperbaric Oxygen Intervention in the Treatment of Diffuse Axonal Injury

2021 ◽  
Vol 5 (4) ◽  
pp. 238-241
Author(s):  
Xinli Feng ◽  
Meng Sun
Keyword(s):  
Treatment Group ◽  
Hyperbaric Oxygen ◽  
Conventional Treatment ◽  
Oxygen Therapy ◽  
Axonal Injury ◽  
Diffuse Axonal Injury ◽  
Average Score ◽  
Hyperbaric Oxygen Treatment ◽  
Conventional Treatment Group ◽  
Oxygen Treatment

Objective: To investigate the efficacy and mechanism of ultra-early hyperbaric oxygen intervention in the treatment of diffuse axonal injury (DAI). Methods: Eighty-six patients with diffuse axonal injury were selected and then divided into an ultra-early hyperbaric oxygen treatment group and a conventional treatment group with 43 patients in each group. The Glasgow Coma Scale (GCS) on the 10th day (10d), 20th day (20d), and 30th day (30d) after treatment and the Glasgow Outcome Score (GOS) 6 months later were observed and compared between both the groups. Results: The average score of the GCS at 10d, 20d, and 30d as well as the GOS 6 months later in the ultra-early hyperbaric oxygen treatment group were higher than those in the conventional treatment group (P < 0.05). Conclusion: Hyperbaric oxygen therapy is one of the unique and effective methods in clinical treatment especially for the treatment of DAI patients and it is worthy of promotion.

Therapeutic Efficacy of Hyperbaric Oxygen on the Severe Acute Mountain Sickness Complicated with MODS

2011 ◽  
Vol 140 ◽  
pp. 238-243
Author(s):  
Qi Quan Zhou ◽  
Xue Feng Zhang ◽  
Ren Zeng Ciwang ◽  
Qiang Zhou ◽  
Yong Fan
Keyword(s):  
Treatment Group ◽  
Hyperbaric Oxygen ◽  
Conventional Therapy ◽  
Oxygen Therapy ◽  
Therapy Group ◽  
Acute Mountain Sickness ◽  
Hyperbaric Oxygen Treatment ◽  
Oxygen Treatment ◽  
Before And After ◽  
Mountain Sickness

Objective: To observe the treatment effects of hyperbaric oxygen on severe acute mountain sickness (ASHS) integrated with multiple organ dysfunction syndromes (MODS). Methods: 2006-2010 admitted to two hospitals in the Tibetan Plateau, 66 cases of patients who got the severe acute mountain sickness complicated by MODS were divided into two groups, 28 cases in the conventional therapy group, 38 cases in hyperbaric oxygen treatment therapy group, oxygen therapy, the conventional therapy concluded oxygen therapy, the treatment of primary disease and enhance the support for treatment of metabolic; hyperbaric oxygen group (was) on the basis of conventional therapy and hyperbaric oxygen therapy was used, the clinical effect of those two groups were compared with; with measured the before and after treatment blood levels of cytokines, to investigate the therapeutic mechanism of hyperbaric oxygen therapy. Results: The efficacy of hyperbaric oxygen treatment group and the treatment time are better than the conventional treatment group, hyperbaric oxygen treatment significantly reduced TNF, IL-6, IL-8 levels, and there is a significant difference between before and after treatment. Conclusion: the method of Hyperbaric oxygen for acute high altitude mountain disease complicated with MODS is reliable and had notable curative effect.

HEALTH TECHNOLOGY ASSESSMENT AND POLICY DECISIONS ON HYPERBARIC OXYGEN TREATMENT

1999 ◽  
Vol 15 (4) ◽  
pp. 661-670 ◽  
Author(s):  
Craig Mitton ◽  
David Hailey
Keyword(s):  
Health Care ◽  
Hyperbaric Oxygen ◽  
Standard Of Care ◽  
Good Evidence ◽  
Sufficient Evidence ◽  
Hyperbaric Oxygen Treatment ◽  
Level Of Evidence ◽  
Capital Costs ◽  
Oxygen Treatment ◽  
The Impact

Objectives: To provide information to health authorities and others on the effectiveness of hyperbaric oxygen treatment (HBOT) and the impact on health services should an additional HBOT facility be established in the provincial health care system.Methods: A literature review on the clinical use of HBOT was conducted, drawing on MEDLINE, EMBASE, and HealthSTAR. For each of 13 conditions, the effectiveness of HBOT was assessed, with reference to a widely used classification of level of evidence. Cost implications were considered for each condition for which there was sufficient evidence of effectiveness. The perspective was that of the payer.Results: Good evidence of effectiveness exists for HBOT for four conditions and HBOT is established as the clinical standard of care for two others. Available evidence did not support the routine use of HBOT for a further seven indications. An additional 59–87 patients per year would be eligible for HBOT if a second facility were established in the province. Improvement in quality of life could be expected for 30–60 persons per year. A new facility would result in identified additional annual expenditure of $108,000. Capital costs could exceed $600,000.Conclusions: On the basis of the available evidence on benefits and costs to routine health care, there did not seem to be a particularly strong case for establishing a second HBOT center in the province. Following the assessment, the health authority made a decision not to provide funding for this additional service.

scholarly journals The Clinical Effects of Hyperbaric Oxygen in the Treatment of Sudden Deafness

2021 ◽  
Vol 5 (4) ◽  
pp. 242-245
Author(s):  
Xinli Feng ◽  
Ying Chang
Keyword(s):  
Treatment Group ◽  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Therapy ◽  
Conventional Treatment ◽  
Oxygen Therapy ◽  
Sudden Deafness ◽  
Hearing Level ◽  
Hyperbaric Oxygen Treatment ◽  
Conventional Treatment Group ◽  
Oxygen Treatment

Objective: To observe the clinical effect of hyperbaric oxygen in the treatment of sudden deafness. Methods: Ninety-six patients with sudden deafness diagnosed by the otolaryngology department were divided into 2 groups which comprised of 48 patients in the conventional treatment group and the other 48 patients in the hyperbaric oxygen treatment group. Both groups were treated with methylcobalamin, vitamin B1, and ginkgo biloba extract. The patients in the hyperbaric oxygen treatment group were given hyperbaric oxygen therapy of 2.0 ATA once a day. Each course of treatment lasted 10 days and after two courses of treatment, the clinical efficacies of the two groups were compared. Results: After two courses of treatment, the effect of treatment in the hyperbaric oxygen treatment group was significantly better than that of the conventional treatment group. Conclusion: Hyperbaric oxygen therapy can effectively improve the hearing level of patients with sudden deafness and the overall effective rate of treatment.

scholarly journals Hyperbaric oxygen treatment of superficial soft tissue lesions in children with oncologic disease

2011 ◽  
Vol 4 (1) ◽  
pp. 1
Author(s):  
Eleonora Cesca ◽  
Giacomo Garetto ◽  
Emanuela Frascella ◽  
Simone Cesaro ◽  
Patrizia Dall'Igna ◽  
...  
Keyword(s):  
Hyperbaric Oxygen ◽  
Oxygen Therapy ◽  
Soft Tissues ◽  
Hyperbaric Oxygen Treatment ◽  
Local Skin ◽  
Pediatric Hematology ◽  
Oxygen Treatment ◽  
Oncological Diseases ◽  
The University ◽  
Superficial Soft Tissue

This study aimed to assess the feasibility and results of hyperbaric oxygen therapy (HOT) as supportive treatment of lesions of superficial soft tissues in children with oncological diseases. This was a retrospective analysis and review of all records of children observed at the Pediatric Hematology-Oncology Department of the University of Padova and treated adjuvantly with HOT. Between 1996 and 2010, 12 patients (5 males and 7 females, median age 7 years, range 0.5-16) underwent HOT. The effectiveness of HOT varied according to the lesion treated. Ten out of 12 patients were cured. Efficacy was most questionable in 2 patients with skin graft and flaps at risk. Compliance to therapy was close to 100%. In just one case, HOT was interrupted for the appearance of local skin metastases close to the site of primary tumor. HOT showed itself to be safe and effective in most patients even those immunocompromised or critically ill.

Efficacy and safety of hyperbaric oxygen treatment in SARS-COV-2 (COVID-19) pneumonia: a systematic review

2021 ◽  
Vol 51 (3) ◽  
pp. 271-281 ◽  
Author(s):  
Sylvain Boet ◽  
◽  
Cole Etherington ◽  
George Djaiani ◽  
Andrea C Tricco ◽  
...  
Keyword(s):  
Systematic Review ◽  
Mechanical Ventilation ◽  
Cohort Study ◽  
Hyperbaric Oxygen ◽  
Case Reports ◽  
Grey Literature ◽  
Hyperbaric Oxygen Treatment ◽  
Invasive Treatment ◽  
Serious Adverse Events ◽  
Oxygen Treatment

Introduction: The need for intubation and mechanical ventilation among COVID-19 patients is associated with high mortality rates and places a substantial burden on the healthcare system. There is a strong pathophysiological rationale suggesting that hyperbaric oxygen treatment (HBOT), a low-risk and non-invasive treatment, may be beneficial for COVID-19 patients. This systematic review aimed to explore the potential effectiveness and safety of HBOT for treating patients with COVID-19. Methods: Medline, Embase, Scopus, and Google Scholar were searched from December 2019 to February 2021, without language restrictions. The grey literature was searched via an internet search engine and targeted website and database searches. Reference lists of included studies were searched. Independent reviewers assessed studies for eligibility and extracted data, with disagreements resolved by consensus or a third reviewer. Risk of bias was assessed using the Newcastle Ottawa Scale. Data were summarised descriptively. Results: Six publications (one cohort study, five case reports/series) met the inclusion criteria with a total of 37 hypoxaemic COVID-19 patients treated with HBOT. Of these 37 patients, the need for intubation and mechanical ventilation and in-hospital survival were assessed for 26 patients across three studies. Of these 26 patients, intubation and mechanical ventilation were not required for 24, and 23 patients survived. No serious adverse events of HBOT in COVID-19 patients were reported. No randomised trials have been published. Conclusions: Limited and weak evidence from non-randomised studies including one propensity-matched cohort study suggests HBOT is safe and may be a promising intervention to optimise treatment and outcomes in hypoxaemic COVID-19 patients. Randomised controlled studies are urgently needed.

Sign in / Sign up

Export Citation Format

Share Document