scholarly journals Highly Efficient Recyclable Sol Gel Polymer Catalyzed One Pot Difunctionalization of Alkynes

Molecules ◽  
2018 ◽  
Vol 23 (8) ◽  
pp. 1879
Author(s):  
Justin Domena ◽  
Carlos Chong ◽  
Qiaxian Johnson ◽  
Bhanu Chauhan ◽  
Yalan Xing
Keyword(s):  
Reaction Time ◽  
Room Temperature ◽  
Functional Group ◽  
Sol Gel ◽  
One Pot ◽  
Short Reaction Time ◽  
Metal Free ◽  
Highly Efficient

Amino-bridged gel polymer P1 was discovered to catalyze alkyne halo-functionalization in excellent yields, regioselectivity, functional group compatibility, and recyclability. We have observed that both aromatic and aliphatic alkynes can be converted to α,α-dihalogenated ketones in the presence of polymer P1 under metal-free conditions at room temperature within a short reaction time.

Chickpea Leaf Exudates: A Highly Efficient Natural Brønsted Acidic Medium for the Synthesis of Pyran-annulated Heterocycles

2021 ◽  
Vol 18 ◽  
Author(s):  
Snehali R. Mali ◽  
Sachinkumar K. Shinde ◽  
Bhagyashree M. Patil ◽  
Rupesh C. Patil ◽  
Suresh S. Patil
Keyword(s):  
Reaction Time ◽  
Acidic Medium ◽  
Room Temperature ◽  
Reaction Medium ◽  
One Pot ◽  
Short Reaction Time ◽  
Highly Efficient ◽  
Acid Type ◽  
Cyclocondensation Reaction ◽  
Reaction Media

: We reported Chickpea leaf exudates (CLE) as a Brønsted acid type naturally available biodegradable, ecofriendly and reusable reaction medium for highly efficient and facile one-pot synthesis of pyran annulated heterocyclic systems like 7-aryl-benzopyrano[4,3-b]benzopyran-6,8-diones, tetrahydrobenzo[b]pyran and dihydropyrano[c]chromenes scaffolds. The analogous products were obtained via tandem Knoevengel-Michael addition and cyclocondensation reaction in ethanol at room temperature with 90-96 % yields in a short reaction time. Moreover, the reaction media containing Bronsted acids can be easily recovered and reused upto five times with a slight decrease in product yields.

scholarly journals A Green, Expeditious, One-Pot Synthesis of 3, 4-Dihydropyrimidin-2(1H)-ones Using a Mixture of Phosphorus Pentoxide-Methanesulfonic Acid at Ambient Temperature

2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
Amulrao Borse ◽  
Mahesh Patil ◽  
Nilesh Patil ◽  
Rohan Shinde
Keyword(s):  
Reaction Time ◽  
Ambient Temperature ◽  
Room Temperature ◽  
Simple Procedure ◽  
Methanesulfonic Acid ◽  
Phosphorus Pentoxide ◽  
One Pot ◽  
Short Reaction Time ◽  
Solvent Free Conditions ◽  
High Yields

An expeditious, one-pot method for the synthesis of 3,4-dihydropyrimidin-2(1H)-ones using a mixture of phosphorus pentoxide-methanesulfonic acid (Eaton’s reagent) at room temperature under solvent-free conditions is described. The salient features of this method include short reaction time, green aspects, high yields, and simple procedure.

scholarly journals Highly efficient, one-pot synthesis of novel bis-spirooxindoles with skeletal diversity via sequential multi-component reaction in PEG-400 as a biodegradable solvent

RSC Advances ◽  
2017 ◽  
Vol 7 (63) ◽  
pp. 39502-39511 ◽  
Author(s):  
Ensieh Safari ◽  
Ammar Maryamabadi ◽  
Alireza Hasaninejad
Keyword(s):  
Reaction Time ◽  
One Pot ◽  
Short Reaction Time ◽  
Peg 400 ◽  
Highly Efficient ◽  
One Pot Synthesis ◽  
Skeletal Diversity

A green, efficient, multi-component protocol has been developed for synthesis of novel bis-spirooxindoles in short reaction time, easy workup and excellent yields.

scholarly journals Pentafluoropropionic Acid: An Efficient and Metal-Free Catalyst for the One-Pot Synthesis of Tetrahydrobenzo[b]pyran Derivatives

2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
Naser Montazeri ◽  
Taghva Noghani ◽  
Mona Ghorchibeigy ◽  
Rozita Zoghi
Keyword(s):  
Reaction Time ◽  
Aromatic Aldehyde ◽  
One Pot ◽  
Short Reaction Time ◽  
Metal Free ◽  
One Pot Synthesis ◽  
Three Component Reaction ◽  
The One ◽  
High Yields

Pentafluoropropionic acid (PFPA) efficiently catalyzes the one-pot, three-component reaction of aromatic aldehyde, malononitrile, and dimedone to yield tetrahydrobenzo[b]pyran derivatives in high yields. This method is of great value because of its easy processing, short reaction time, environmentally, and high yields.

Synthesis of a series of novel 2,3-dihydrofuranonaphthoquinone derivatives

2017 ◽  
Vol 41 (8) ◽  
pp. 448-451 ◽  
Author(s):  
Maryam Salari ◽  
Mohammad H. Mosslemin ◽  
Alireza Hassanabadi
Keyword(s):  
Reaction Time ◽  
Green Chemistry ◽  
Organic Solvent ◽  
Aromatic Aldehyde ◽  
Efficient Synthesis ◽  
One Pot ◽  
Short Reaction Time ◽  
Highly Efficient ◽  
One Pot Condensation ◽  
High Yields

A green and highly efficient synthesis of 12 novel trans-2-(4-chlorobenzoyl)-3-aryl-2,3-dihydronaphtho[2,3- b]furan-4,9-diones has been achieved via a three-component, one-pot condensation of 2-[2-(4-chlorophenyl)-2-oxoethyl)]isoquinolinium bromide with 2-hydroxy-1,4-naphthoquinone and an aromatic aldehyde in the presence of catalytic amounts of choline hydroxide in water under reflux conditions. The advantages of this method are a short reaction time, high yields and the avoidance of any hazardous organic solvent. Therefore, this procedure can be classified as green chemistry.

An Improved Synthesis of Urea Derivatives from N-Acylbenzotriazole via Curtius Rearrangement

Synthesis ◽  
2019 ◽  
Vol 51 (18) ◽  
pp. 3443-3450 ◽  
Author(s):  
Anoop S. Singh ◽  
Anand K. Agrahari ◽  
Sumit K. Singh ◽  
Mangal S. Yadav ◽  
Vinod K. Tiwari
Keyword(s):  
Reaction Time ◽  
Column Chromatography ◽  
High Yield ◽  
Reaction Conditions ◽  
One Pot ◽  
Urea Derivatives ◽  
Curtius Rearrangement ◽  
Short Reaction Time ◽  
Metal Free ◽  
Salient Features

The good leaving tendency of the benzotriazole moiety has been exploited for the synthesis of symmetric, unsymmetric, N-acyl, and cyclic ureas in good yields from N-acylbenzotriazoles by treating the latter with various amines in the presence of TMSN3/Et3N in a sealed tube. The salient features of the devised protocol includes the high-yield, mild, metal-free, one-pot reaction conditions, and short reaction time. Furthermore, in many cases, no column chromatography is required for the purification.

Phosphomolybdic Acid (PMA)-catalyzed One-pot Synthesis of 2,3- Dihydroquinazolines

2019 ◽  
Vol 16 (8) ◽  
pp. 683-687
Author(s):  
Chuanhuan Chen ◽  
A. Xuejiao ◽  
Xia Li ◽  
Guoli Huang ◽  
Bo Liu
Keyword(s):  
Reaction Time ◽  
Present Method ◽  
Room Temperature ◽  
Phosphomolybdic Acid ◽  
New Method ◽  
High Yield ◽  
One Pot ◽  
Short Reaction Time ◽  
One Pot Synthesis

We have developed a new method for the synthesis of 2,3-dihydroquinazolin-4(1H)-ones in good to excellent yields via phosphomolybdic acid (PMA)-catalyzed cyclocondensation of 2- aminobenzamides with aldehydes or ketones in N,N-dimethylformamide (DMF) at room temperature. The present method proves to be efficient in terms of short reaction time, high yield, simple workup and easy purification.

scholarly journals ZnO as an Efficient and Inexpensive Catalyst for One Pot Synthesis of 2, 4, 5 -Triphenyl-1H- imidazole Derivatives at Room Temperature

2011 ◽  
Vol 8 (3) ◽  
pp. 1339-1345 ◽  
Author(s):  
Babasaheb P. Bandgar ◽  
Baliram S. Hote ◽  
Balaji L. Korbad ◽  
Sachin A. Patil
Keyword(s):  
Reaction Time ◽  
Aromatic Aldehyde ◽  
Room Temperature ◽  
Synthetic Methods ◽  
High Yield ◽  
One Pot ◽  
Short Reaction Time ◽  
Reaction Condition ◽  
One Pot Synthesis ◽  
Environmental Friendly

An improved and rapid one pot synthesis of 2,4,6-triphenyl-1H-imidazoles on condensation with benzil, aromatic aldehyde and NH4OAc has been carried out using ZnO as an efficient and inexpensive catalyst in high yield at room temperature. The short reaction time, good yields (60-93%), environmental friendly procedure, mild reaction condition and convenient operation are important advantage of these synthetic methods.

Iodine-Mediated Multi-Component Reactions: Readily Access to Tetrazoles and Guanidines

2020 ◽  
Vol 17 ◽  
Author(s):  
Bajivali Shaik ◽  
Mohan Seelam ◽  
Ramana Tamminana ◽  
Prasad Rao Kammela
Keyword(s):  
Reaction Time ◽  
Benzoyl Chloride ◽  
Functional Group ◽  
Molecular Iodine ◽  
Environmentally Benign ◽  
Reaction Conditions ◽  
One Pot ◽  
Short Reaction Time ◽  
One Pot Synthesis ◽  
High Yields

Abstract: Environmentally benign syntheses of One-pot sequential reactions of benzoyl chloride with amines followed by the treatment of molecular I2 reagent under basic conditions provide benzoyl tetrazoles and guanidines in moderate to excel-lent yields. This one-pot synthesis has several advantages such as mild reaction conditions, short reaction time, convenient workup, high yields, using cheap and readily available reagent molecular Iodine. In addition, functional group tolerance has been explored

Copper-Catalyzed Highly Efficient Esterification of Aldehydes with N-Hydroxyphthalimide via Cross-Dehydrogenative Coupling in Water at Room Temperature

Synlett ◽  
2017 ◽  
Vol 28 (11) ◽  
pp. 1321-1326 ◽  
Author(s):  
Can Jin ◽  
Weike Su ◽  
Zhicheng Guo ◽  
Xinpeng Jiang ◽  
Jiadi Zhou ◽  
...  
Keyword(s):  
Reaction Time ◽  
Efficient Method ◽  
Room Temperature ◽  
Coupling Reaction ◽  
Short Reaction Time ◽  
Mild Conditions ◽  
Highly Efficient ◽  
Dehydrogenative Coupling ◽  
First Time

A copper-catalyzed cross-dehydrogenative coupling reaction between N-hydroxyphthalimide and aldehydes using PhI(OAc)2 as an oxidant is described. It is reported for the first time to synthesize NHPI esters in water, providing the corresponding NHPI esters in moderate to good yields. This facile and efficient method is eco-friendly and possesses the advantages of mild conditions, short reaction time, and broad substrate scope.

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