scholarly journals Bimodal Nd-Doped LuVO4 Nanoprobes Functionalized with Polyacrilic Acid for X-Ray Computed Tomography and NIR Luminescent Imaging

Nanomaterials ◽  
2020 ◽  
Vol 10 (1) ◽  
pp. 149 ◽  
Author(s):  
Nuria O Nuñez ◽  
Fernando Cussó ◽  
Eugenio Cantelar ◽  
Beatriz Martin-Gracia ◽  
Jesús M de la Fuente ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Colloidal Stability ◽  
Near Infrared ◽  
High Cell ◽  
X Ray ◽  
Time In Literature ◽  
Potential Applications ◽  
Intense Luminescence ◽  
X Ray Computed ◽  
First Time

Uniform Nd3+-doped LuVO4 nanophosphors have been synthesized for the first time in literature by using a poliol-based method at 120 °C from Nd3+ and vanadate precursors. After optimizing the Nd doping level, these phosphors present intense luminescence in the near-infrared biological windows. The X-ray attenuation capacity of the optimum nanophosphor has been found to be higher than that of a commercial X-ray computed tomography contrast agent. After surface coating with polyacrylic acid, such nanoparticles present high colloidal stability in physiological pH medium and high cell viability. Because of these properties, the developed Nd3+-doped LuVO4 nanoparticles have potential applications as a bimodal probe for NIR luminescent bioimaging and X-ray computed tomography.

scholarly journals The anatomy of the palate in Early Triassic Chaohusaurus brevifemoralis (Reptilia: Ichthyosauriformes) based on digital reconstruction

PeerJ ◽  
2021 ◽  
Vol 9 ◽  
pp. e11727
Author(s):  
Ya-Lei Yin ◽  
Cheng Ji ◽  
Min Zhou
Keyword(s):  
Computed Tomography ◽  
High Resolution ◽  
Ct Scanning ◽  
Lower Triassic ◽  
Early Triassic ◽  
Single Row ◽  
X Ray ◽  
Digital Reconstruction ◽  
X Ray Computed ◽  
First Time

The palatal anatomy of ichthyosauriforms remains largely unknown. Here, the complete palate of the early-branching ichthyosauriform Chaohusaurus brevifemoralis is reconstructed and described for the first time with the assistance of high-resolution X-ray computed tomography (CT) scanning on the basis of the three-dimensionally preserved skull of its paratype (GMPKU-P-3086) from the Lower Triassic of South China. The reconstruction reveals new palatal features of C. brevifemoralis. The palatine contacts the jugal directly, which is observed in ichthyosauriforms for the first time. A single row of denticles is present on each side of the palate. The vomer exceeds the anterior and posterior margins of the internal naris. The pterygoid is posterior to the internal naris. The epipterygoid is present and the ectopterygoid is absent.

scholarly journals TERATOMA OF THE KIDNEY: A RARE CASE OF EXTRAGONADAL GERM CELL TUMOR

2017 ◽  
Vol 14 (3) ◽  
pp. 202-207
Author(s):  
Tamara R. Panferova ◽  
Timur T. Valiev ◽  
Oleg P. Bliznyukov ◽  
Olga A. Kapkova
Keyword(s):  
Computed Tomography ◽  
Rare Case ◽  
Clinical Observation ◽  
Mature Teratoma ◽  
Morphological Characteristics ◽  
Cell Tumor ◽  
X Ray ◽  
Domestic Literature ◽  
X Ray Computed ◽  
First Time

For the first time, a clinical observation of a rare case of a mature teratoma of the kidney in a child aged 5 months is presented in domestic literature. A literature review is given on this topic. The clinical picture, characteristic signs of a tumor during ultrasound and X-ray computed tomography, the results of a surgical procedure receive full coverage. Special attention is paid to the morphological characteristics of a mature teratoma.

scholarly journals Encapsulation of Upconversion Nanoparticles in Periodic Mesoporous Organosilicas

Molecules ◽  
2019 ◽  
Vol 24 (22) ◽  
pp. 4054 ◽  
Author(s):  
Saher Rahmani ◽  
Chiara Mauriello Jimenez ◽  
Dina Aggad ◽  
Daniel González-Mancebo ◽  
Manuel Ocaña ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Near Infrared ◽  
Sol Gel ◽  
Upconversion Nanoparticles ◽  
X Ray ◽  
Mesoporous Organosilica ◽  
The Matrix ◽  
X Ray Computed ◽  
Mesoporous Organosilicas ◽  
Cancer Theranostics

(1) Background: Nanomedicine has recently emerged as a promising field, particularly for cancer theranostics. In this context, nanoparticles designed for imaging and therapeutic applications are of interest. We, therefore, studied the encapsulation of upconverting nanoparticles in mesoporous organosilica nanoparticles. Indeed, mesoporous organosilica nanoparticles have been shown to be very efficient for drug delivery, and upconverting nanoparticles are interesting for near-infrared and X-ray computed tomography imaging, depending on the matrix used. (2) Methods: Two different upconverting-based nanoparticles were synthesized with Yb3+-Er3+ as the upconverting system and NaYF4 or BaLuF5 as the matrix. The encapsulation of these nanoparticles was studied through the sol-gel procedure with bis(triethoxysilyl)ethylene and bis(triethoxysilyl)ethane in the presence of CTAB. (3) Results: with bis(triethoxysilyl)ethylene, BaLuF5: Yb3+-Er3+, nanoparticles were not encapsulated, but anchored on the surface of the obtained mesoporous nanorods BaLuF5: Yb3+-Er3+@Ethylene. With bis(triethoxysilyl)ethane, BaLuF5: Yb3+-Er3+ and NaYF4: Yb3+-Er3+nanoparticles were encapsulated in the mesoporous cubic structure leading to BaLuF5: Yb3+-Er3+@Ethane and NaYF4: Yb3+-Er3+@Ethane, respectively. (4) Conclusions: upconversion nanoparticles were located on the surface of mesoporous nanorods obtained by hydrolysis polycondensation of bis(triethoxysilyl)ethylene, whereas encapsulation occurred with bis(triethoxysilyl)ethane. The later nanoparticles NaYF4: Yb3+-Er3+@Ethane or BaLuF5: Yb3+-Er3+@Ethane were promising for applications with cancer cell imaging or X-ray-computed tomography respectively.

Application of 3-D X-Ray Computed Tomography for the In Situ Visualization of the SiC Crystal Growth Interface during PVT Bulk Growth

2013 ◽  
Vol 740-742 ◽  
pp. 27-30 ◽  
Author(s):  
Georg Neubauer ◽  
Michael Salamon ◽  
Florian Roider ◽  
Norman Uhlmann ◽  
Peter J. Wellmann
Keyword(s):  
Computed Tomography ◽  
Crystal Growth ◽  
Vapor Transport ◽  
Growth Interface ◽  
X Ray ◽  
Bulk Growth ◽  
Growth System ◽  
X Ray Computed ◽  
First Time

In this paper, we present for the first time an in-situ 3-D reconstruction of the SiC crystal growth interface using X-ray computed tomography (CT). We show that the shape of the growth interface can be determined with high precision at growth temperatures above 2100 °C in a conventional 3” PVT (physical vapor transport) growth system.

The Use of X-ray Computed Tomography to Assess the Intrathyroidal Iodine Concentration and its Storage in the Thyroid Gland

2020 ◽  
Vol 65 (3) ◽  
pp. 73-76
Author(s):  
I. Tomashevskiy ◽  
I. Kurnikova ◽  
R. Sargar
Keyword(s):  
Computed Tomography ◽  
Thyroid Gland ◽  
Thyroid Hormones ◽  
Functional Impairment ◽  
Iodine Concentration ◽  
The Body ◽  
X Ray ◽  
Iodine Prophylaxis ◽  
X Ray Computed ◽  
First Time

In this lecture, the need of using X-ray computed tomography (CT) to assess the intrathyroidal iodine concentration and its storage in the thyroid gland has being discussed. Due to the fact that 80 % of intrathyroidal iodine is located in the phenolic ring of thyroid hormones, which are structurally located in colloid-thyroglobulin follicles as a hormonal depot, the parameter of intrathyroidal iodine (PII) is an indicator of the stores of iodine-containing thyroid hormones directly in the organ. A decrease in intrathyroidal iodine indicates a significant functional impairment of storing thyroid hormones in the colloid of thyroglobulin of the thyroid follicles and is an early highly accurate prognostic sign of the formation of gland dysfunction. Due to the compensatory capabilities of the body, this dysfunction may appear late onset (for example, 2 months after detecting a decrease in intrathyroidal iodine). The most convenient and affordable method for determining intrathyroidal iodine is CT with two types of tomographs: 1) standard by which intrathyroidal iodine is determined by the density of the thyroid gland in Hounsfield units (HU); 2) tomographs with the option of assessing the concentration of intrathyroidal iodine (CII) in the most common units of measurement – mg/g or μg/g (used since 2016). If necessary, the conversion of some units of intrathyroidal iodine to others has the formula: CII (in μg/g) = ([density in HU] – 65) / 104. Based on the literature and our own research results, for the first time, we calculated the limits of normal intrathyroidal iodine fluctuations in euthyroid individuals, which are 85–140 HU units or 200–700 μg/g intrathyroidal iodine. Identification of the examined intrathyroidal iodine beyond the indicated fluctuations indicates the functional impairment of storing thyroid hormones, which ultimately will lead to hypothyroidism or hyperthyroidism (except when the patient is taking levothyroxine, mercazole, β-blockers – drugs that reduce intrathyroidal iodine). For the first time, an algorithm is presented for differential diagnosis of iodine-deficient and iodine-induced thyroid dysfunctions, which can only be done using CT: if there is a functional impairment of the thyroid gland with intrathyroidal iodinelevel less than 85 units of HU or 200 μg/g CII, then it is considered iodine deficient; with intrathyroidal iodinelevel more than 140 units of HU or 700 μg/g of CII, it is considered iodine-induced. The algorithm for the prevention of iodine-induced thyroid pathology with iodine prophylaxis is that iodine prophylaxis should not be prescribed or continued when intrathyroidal iodinelevel is 140 units of HU or 700 μg/g of CII or more.

Near-infrared optical and X-ray computed tomography dual-modal imaging probe based on novel lanthanide-doped K0.3Bi0.7F2.4 upconversion nanoparticles

Nanoscale ◽  
2018 ◽  
Vol 10 (3) ◽  
pp. 1394-1402 ◽  
Author(s):  
Ran An ◽  
Pengpeng Lei ◽  
Peng Zhang ◽  
Xia Xu ◽  
Jing Feng ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Near Infrared ◽  
Upconversion Nanoparticles ◽  
X Ray ◽  
Imaging Probe ◽  
X Ray Computed

Novel citrate-coated K0.3Bi0.7F2.4:20% Yb3+/0.5% Tm3+ could be employed as a bioprobe for NIR optical and CT dual-modal imaging.

Photosensitizer loaded PEG-MoS2–Au hybrids for CT/NIRF imaging-guided stepwise photothermal and photodynamic therapy

2017 ◽  
Vol 5 (12) ◽  
pp. 2286-2296 ◽  
Author(s):  
Li Liu ◽  
Jinping Wang ◽  
Xiaoxiao Tan ◽  
Xiaojuan Pang ◽  
Qing You ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Photodynamic Therapy ◽  
Gold Nanoparticle ◽  
Molybdenum Disulfide ◽  
Near Infrared ◽  
X Ray ◽  
Nirf Imaging ◽  
X Ray Computed ◽  
Molybdenum Disulfide Nanosheets ◽  
Near Infrared Fluorescence Imaging

We develop X-ray computed tomography/near-infrared fluorescence imaging for visually guiding the photothermal/photodynamic therapy of antitumor nanocomposites (PEG-MoS2–Au–Ce6), by adsorbing chlorin e6 to the gold nanoparticle-decorated molybdenum disulfide nanosheets.

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