Association of Blood Mercury Level with the Risk of Depression According to Fish Intake Level in the General Korean Population: Findings from the Korean National Health and Nutrition Examination Survey (KNHANES) 2008–2013

Mercury is a cumulative neurotoxic agent, exposure to high levels of which may increase the risk of psychiatric symptoms. The purpose of this study was to examine the associations between blood mercury and depression risk in Korean adults. We analyzed the Korean National Health and Nutrition Examination Survey (KNHANES) with 11,754 participants (male: 5834 female: 5920) aged ≥19 years from 2008 to 2013. The associations of blood mercury with risk of depression were estimated using multivariate logistic regression after adjustment for potential confounders. We found a significantly increased risk of depression in the highest quintile for blood mercury (multivariate OR = 2.05; 95% CI = 1.20–3.48; p trend = 0.03) among female, but not male. A stratification analysis by fish intake showed that the association between depression and blood mercury was strengthened (OR = 4.00; 95% CI = 1.51–10.6; p trend = 0.015) among females with the lowest tertile of fish intake. The results of this study suggest that higher levels of blood mercury, especially in cases of lower fish intake, are positively associated with the risk of depression in Korean women.

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Blood Mercury Levels in Relation to Overweight in Korean Children and Adolescents: Results From The Korean National Health and Nutrition Examination Survey 2010-2013

10.21203/rs.3.rs-146410/v1 ◽

2021 ◽

Author(s):

KY YOUNG CHO

Keyword(s):

Children And Adolescents ◽

National Health ◽

Mercury Level ◽

Overweight And Obesity ◽

Mercury Exposure ◽

Seafood Consumption ◽

Nutrition Examination Survey ◽

Korean Children ◽

Health And Nutrition ◽

Blood Mercury

Abstract Background: Previous researches for adults have demonstrated a substantial role of mercury exposure in the development of overweight and obesity development, but those findings are inconsistent. Although children and adolescents are more susceptible to the toxic effect of mercury compared to adults, the research of overweight and obesity related to mercury exposure in children and adolescent is scarce. This study aimed to investigate the association of blood mercury levels with body mass index (BMI) in Korean children and adolescents.Methods: The cross-sectional data analyzed were obtained from 1327 participants (age: 10-18 years, 672 males and 655 females) who completed the Korean National Health and Nutrition Examination Survey 2010-2013. The adjusted covariates were age, sex, household income, total intake of seafood in the previous 24 hours, and current status of alcohol consumption and smoking. Results: The adjusted geometric mean blood mercury level was 2.19 µg/L and increased significantly in the overweight group and the highest seafood consumption quartile compared with the level in the normal weight group and lowest seafood consumption quartile, respectively (P < 0.001). The adjusted blood mercury levels were significantly positively correlated with BMI in all participants and females (P < 0.05). When stratified by age and sex, all participants and males in the highest blood mercury level quartile were at higher risk of overweight than those in the lowest quartile (odds ratios [95% confidential intervals, CIs]: 1.78 [1.06-2.98], and 2.06 [1.01-4.23], respectively) after adjusting for the covariates (P < 0.05). Receiver operating characteristic analysis of blood mercury levels for predicting overweight revealed that the area under the curve was 0.603 (P < 0.001).Conclusions: Our study suggested a significant association between mercury exposure and the risk of overweight in Korean children and adolescents.

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Relationship between Blood Mercury Level and Risk of Cardiovascular Diseases: Results from the Fourth Korea National Health and Nutrition Examination Survey (KNHANES IV) 2008-2009

Preventive Nutrition and Food Science ◽

10.3746/pnf.2014.19.4.333 ◽

2014 ◽

Vol 19 (4) ◽

pp. 333-342 ◽

Cited By ~ 15

Author(s):

Young-Nam Kim ◽

Young A Kim ◽

Ae-Ri Yang ◽

Bog-Hieu Lee

Keyword(s):

Cardiovascular Diseases ◽

National Health ◽

Mercury Level ◽

Nutrition Examination Survey ◽

Health And Nutrition ◽

Blood Mercury

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Blood mercury level and blood pressure among US women: results from the National Health and Nutrition Examination Survey 1999–2000

Environmental Research ◽

10.1016/j.envres.2004.05.001 ◽

2005 ◽

Vol 97 (2) ◽

pp. 195-200 ◽

Cited By ~ 102

Author(s):

Suma Vupputuri ◽

Matthew P. Longnecker ◽

Julie L. Daniels ◽

Xuguang Guo ◽

Dale P. Sandler

Keyword(s):

Blood Pressure ◽

National Health ◽

Mercury Level ◽

Nutrition Examination Survey ◽

Health And Nutrition ◽

Blood Mercury

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Association of Blood Mercury Levels with the Risks of Overweight and High Waist-to-Height Raito in Children and Adolescents: Data from the Korean National Health and Nutrition Examination Survey

Children ◽

10.3390/children8121087 ◽

2021 ◽

Vol 8 (12) ◽

pp. 1087

Author(s):

Ky Young Cho

Keyword(s):

Children And Adolescents ◽

National Health ◽

Mercury Level ◽

Overweight And Obesity ◽

Mercury Exposure ◽

Dietary Factors ◽

Nutrition Examination Survey ◽

Korean Children ◽

Health And Nutrition ◽

Blood Mercury

A previous study in adults demonstrated the substantial role of mercury exposure in the development of overweight and obesity. Although children and adolescents are more susceptible to the toxic effects of mercury than adults, studies on the association of overweight and obesity with mercury exposure is limited. This study aimed to investigate the association of blood mercury levels with the body mass index (BMI) and waist-to-height ratio (WHtR) as obesity indices in Korean children and adolescents. The analyzed cross-sectional data were obtained from 1327 participants (age: 10–18 years; 672 male and 655 female) who completed the Korean National Health and Nutrition Examination Survey 2010–2013. The covariates included sociodemographic factors (age, sex, and household income), dietary factors (fish, shellfish, and seaweed consumption), lifestyle factors (alcohol consumption, smoking status, and exercise), and blood hematocrit levels. The adjusted geometric mean blood mercury level was 2.19 µg/L, and the level of mercury was significantly higher in the overweight (BMI ≥ 85th gender and age-specific percentiles) and high WHtR (cutoff: ≥0.5) groups than in the normal group. In all the participants, the blood mercury levels were significantly positively associated with the BMI and WHtR after adjusting for all covariates (p < 0.05). All the participants in the highest blood mercury level quartile were at a higher risk for overweight and a high WHtR than those in the lowest quartile after adjusting for all covariates (p < 0.05). Our study suggests a significant association between mercury exposure and the risks of overweight and high WHtR in Korean children and adolescents.

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Association between Dietary Inflammatory Index and kidney stones in US adults: Data from the NHANES 2007-2016

Public Health Nutrition ◽

10.1017/s1368980021000793 ◽

2021 ◽

pp. 1-27

Author(s):

Chichen Zhang ◽

Shi Qiu ◽

Haiyang Bian ◽

Bowen Tian ◽

Haoyuan Wang ◽

...

Keyword(s):

National Health ◽

Kidney Stones ◽

Primary Outcome ◽

Secondary Outcome ◽

Nutrition Examination Survey ◽

Dietary Inflammatory Index ◽

Inflammatory Index ◽

Health And Nutrition ◽

Multivariate Adjustment ◽

Increased Risk

Abstract Objective: We evaluate the association between the Dietary Inflammatory Index (DII) and kidney stones. Design: We performed a cross-sectional analysis using data from National Health and Nutrition Examination Survey. Dietary intake information was assessed using first 24-HR dietary recall interviews, and the Kidney Conditions was presented by questionnaire. The primary outcome was to investigate the association between DII and incidence of kidney stones, and the secondary outcome was to assess the association between DII and nephrolithiasis recurrence. Setting: The National Health and Nutrition Examination Survey (NHANES), 2007-2016. Participants: The study included 25984 NHANES participants, whose data on DII and kidney stones were available, of whom 2439 reported a history of kidney stones. Results: For the primary outcome, after fully multivariate adjustment, DII score is positively associated with the risk of kidney stones (OR = 1.07; 95% CI: [1.04–1.10]). Then, compared Q4 with Q1, a significant 38% increased likelihood of nephrolithiasis was observed. (OR=1.38; 95% CI: [1.19–1.60]). For the secondary outcome, the multivariate regression analysis showed that DII score is positively correlated with nephrolithiasis recurrence (OR=1.07; 95% CI: [1.00–1.15]). The results noted that higher DII scores (Q3 and Q4) are positively associated with a significant 48% and 61% increased risk of nephrolithiasis recurrence compared with the reference after fully multivariate adjustment. (OR=1.48; 95% CI: [1.07–2.05]; OR=1.61; 95% CI: [1.12–2.31]). Conclusions: Our findings revealed that increased intake of pro-inflammatory diet, as a higher DII score, is correlated with increased odds of kidney stones incidence and recurrence.

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Association of blood mercury levels with nonmelanoma skin cancer in the U.S.A. using National Health and Nutrition Examination Survey data (2003–2016)

British Journal of Dermatology ◽

10.1111/bjd.18797 ◽

2020 ◽

Vol 183 (3) ◽

pp. 480-487 ◽

Cited By ~ 1

Author(s):

J. Rhee ◽

T.M. Vance ◽

R. Lim ◽

D.C. Christiani ◽

A.A. Qureshi ◽

...

Keyword(s):

Skin Cancer ◽

Survey Data ◽

National Health ◽

Nonmelanoma Skin Cancer ◽

Nutrition Examination Survey ◽

Health And Nutrition ◽

Blood Mercury

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Disparities in Hepatitis B Vaccine Coverage by Race/Ethnicity: The National Health and Nutrition Examination Survey (NHANES) 2015–2016

Diseases ◽

10.3390/diseases8020010 ◽

2020 ◽

Vol 8 (2) ◽

pp. 10

Author(s):

Azad R. Bhuiyan ◽

Nusrat Kabir ◽

Amal K. Mitra ◽

Oluwabunmi Ogungbe ◽

Marinelle Payton

Keyword(s):

Logistic Regression ◽

Hepatitis B ◽

National Health ◽

Mexican Americans ◽

Vaccine Coverage ◽

Nutrition Examination Survey ◽

Multivariate Logistic Regression ◽

Hbv Vaccine ◽

Health And Nutrition ◽

Race Ethnicity

Hepatitis B virus (HBV) infection is the most common form of viral hepatitis and remains a global public health problem, even though the HBV vaccine is available. HBV leads to chronic liver disease, including cirrhosis, liver cancer, and death. This study aimed to identify disparities in HBV vaccine coverage with the serological test by race/ethnicity, adjusting for gender and age. In this study, 5735 adult participants were included, obtaining data from the National Health and Nutrition Examination Survey (NHANES), 2015–2016. Proc survey frequency, bivariate- and multivariate logistic regression in the weighted sample were performed due to the complex survey design of NHANES. Data were analyzed using SAS, version 9.2.4. The overall prevalence of HBV vaccine coverage was only 23.3% (95% CI: 20.7%, 25.9%). In a multivariate logistic regression model, data showed that Mexican Americans (OR 0.57, 95% CI: 0.38, 0.86) and African Americans (OR 0.70, 95% CI 0.56, 0.84) had lower vaccine coverage compared to Whites. Females had (OR 1.55, 95% CI: 1.30, 1.85) higher vaccine coverage compared to men. Older age groups (30–49 years) (OR 0.41, 95% CI: 0.32, 0.52) and age group ≥ 50 years (OR 0.18, 95% CI 0.14, 0.23) had lower vaccine coverage compared to younger adults aged 18–29 years.

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