scholarly journals Association of Blood Mercury Levels with the Risks of Overweight and High Waist-to-Height Raito in Children and Adolescents: Data from the Korean National Health and Nutrition Examination Survey

Children ◽  
2021 ◽  
Vol 8 (12) ◽  
pp. 1087
Author(s):  
Ky Young Cho

A previous study in adults demonstrated the substantial role of mercury exposure in the development of overweight and obesity. Although children and adolescents are more susceptible to the toxic effects of mercury than adults, studies on the association of overweight and obesity with mercury exposure is limited. This study aimed to investigate the association of blood mercury levels with the body mass index (BMI) and waist-to-height ratio (WHtR) as obesity indices in Korean children and adolescents. The analyzed cross-sectional data were obtained from 1327 participants (age: 10–18 years; 672 male and 655 female) who completed the Korean National Health and Nutrition Examination Survey 2010–2013. The covariates included sociodemographic factors (age, sex, and household income), dietary factors (fish, shellfish, and seaweed consumption), lifestyle factors (alcohol consumption, smoking status, and exercise), and blood hematocrit levels. The adjusted geometric mean blood mercury level was 2.19 µg/L, and the level of mercury was significantly higher in the overweight (BMI ≥ 85th gender and age-specific percentiles) and high WHtR (cutoff: ≥0.5) groups than in the normal group. In all the participants, the blood mercury levels were significantly positively associated with the BMI and WHtR after adjusting for all covariates (p < 0.05). All the participants in the highest blood mercury level quartile were at a higher risk for overweight and a high WHtR than those in the lowest quartile after adjusting for all covariates (p < 0.05). Our study suggests a significant association between mercury exposure and the risks of overweight and high WHtR in Korean children and adolescents.

2021 ◽  
Author(s):  
KY YOUNG CHO

Abstract Background: Previous researches for adults have demonstrated a substantial role of mercury exposure in the development of overweight and obesity development, but those findings are inconsistent. Although children and adolescents are more susceptible to the toxic effect of mercury compared to adults, the research of overweight and obesity related to mercury exposure in children and adolescent is scarce. This study aimed to investigate the association of blood mercury levels with body mass index (BMI) in Korean children and adolescents.Methods: The cross-sectional data analyzed were obtained from 1327 participants (age: 10-18 years, 672 males and 655 females) who completed the Korean National Health and Nutrition Examination Survey 2010-2013. The adjusted covariates were age, sex, household income, total intake of seafood in the previous 24 hours, and current status of alcohol consumption and smoking. Results: The adjusted geometric mean blood mercury level was 2.19 µg/L and increased significantly in the overweight group and the highest seafood consumption quartile compared with the level in the normal weight group and lowest seafood consumption quartile, respectively (P < 0.001). The adjusted blood mercury levels were significantly positively correlated with BMI in all participants and females (P < 0.05). When stratified by age and sex, all participants and males in the highest blood mercury level quartile were at higher risk of overweight than those in the lowest quartile (odds ratios [95% confidential intervals, CIs]: 1.78 [1.06-2.98], and 2.06 [1.01-4.23], respectively) after adjusting for the covariates (P < 0.05). Receiver operating characteristic analysis of blood mercury levels for predicting overweight revealed that the area under the curve was 0.603 (P < 0.001).Conclusions: Our study suggested a significant association between mercury exposure and the risk of overweight in Korean children and adolescents.


2018 ◽  
Vol 31 (2) ◽  
pp. 117-125 ◽  
Author(s):  
Yong Min Kim ◽  
So Hyun Kim ◽  
Young Suk Shim

Abstract Background: This study aimed to evaluate the relationship between sodium intake and insulin resistance indices. Methods: A total of 718 Korean children and adolescents (411 boys) aged 10–18 years who participated in the Korea National Health and Nutrition Examination Survey (KNHANES) were included in the study. The urinary sodium to urinary creatinine ratio was used as a surrogate for sodium intake. The homeostatic model assessment of insulin resistance (HOMA-IR) and the quantitative insulin sensitivity check index (QUICKI) were used as indices of insulin resistance. Results: The mean urinary sodium to urinary creatinine ratio was 11.34 in males and 10.17 in females. The urinary sodium to urinary creatinine ratio was significantly positively correlated with HOMA-IR (r=0.165, p<0.001) and inversely correlated with QUICKI (r=−0.181, p<0.001) in Pearson’s correlation analyses. In a multivariate linear regression analysis, the urinary sodium to urinary creatinine ratio was independently and significantly positively associated with HOMA-IR (β=0.073, p=0.018) and significantly inversely associated with QUICKI (β=−0.080, p=0.007) after adjustment for possible confounders. HOMA-IR was independently and significantly positively associated with the urinary sodium to urinary creatinine ratio (β=0.087, p=0.018), whereas QUICKI was independently and significantly negatively associated with the urinary sodium to urinary creatinine ratio (β=−0.097, p=0.009) after controlling for confounders. Conclusions: Our results suggest that sodium intake, as estimated by the urinary sodium to urinary creatinine ratio, may be independently associated with insulin resistance in children and adolescents.


Nutrients ◽  
2020 ◽  
Vol 12 (1) ◽  
pp. 189
Author(s):  
Kyung Won Kim ◽  
Sundara Raj Sreeja ◽  
Minji Kwon ◽  
Ye Lee Yu ◽  
Mi Kyung Kim

Mercury is a cumulative neurotoxic agent, exposure to high levels of which may increase the risk of psychiatric symptoms. The purpose of this study was to examine the associations between blood mercury and depression risk in Korean adults. We analyzed the Korean National Health and Nutrition Examination Survey (KNHANES) with 11,754 participants (male: 5834 female: 5920) aged ≥19 years from 2008 to 2013. The associations of blood mercury with risk of depression were estimated using multivariate logistic regression after adjustment for potential confounders. We found a significantly increased risk of depression in the highest quintile for blood mercury (multivariate OR = 2.05; 95% CI = 1.20–3.48; p trend = 0.03) among female, but not male. A stratification analysis by fish intake showed that the association between depression and blood mercury was strengthened (OR = 4.00; 95% CI = 1.51–10.6; p trend = 0.015) among females with the lowest tertile of fish intake. The results of this study suggest that higher levels of blood mercury, especially in cases of lower fish intake, are positively associated with the risk of depression in Korean women.


2013 ◽  
Vol 17 (11) ◽  
pp. 2489-2495 ◽  
Author(s):  
Jong Geun Im ◽  
Shin Hye Kim ◽  
Gyeong-yoon Lee ◽  
Hyojee Joung ◽  
Mi-Jung Park

AbstractObjectiveThe present study aimed to assess the adequacy of Ca intake and major food sources of Ca in Korean children and adolescents.DesignA cross-sectional study.SettingData from the Korean National Health and Nutrition Examination Survey (KNHANES) 2007–2010. We analysed the daily Ca intake, major food sources of Ca and the prevalence of inadequate Ca intake in the study population. Ca intake was categorized as inadequate when the participant's daily Ca intake was less than the Estimated Average Requirement.SubjectThe study population consisted of 7233 children and adolescents (3973 boys, 3260 girls; aged 1–18 years).ResultsMean Ca intake was 510·2 mg/d in boys and 431·7 mg/d in girls. Overall, 75·0 % of adolescents (boys 71·6 %, girls 79·1 %) had inadequate Ca intake. The prevalence of inadequate Ca intake increased significantly from toddlers (45–55 %) to adolescents (78–86 %) in both genders. The highest ranked food sources for Ca were dairy products (35·0 %), followed by vegetables (17·3 %), grains (11·3 %) and seafood (9·9 %). Ca intake from dairy products decreased significantly from 57 % in toddlers to 30 % in adolescents, while Ca intakes from other foods increased with age.ConclusionsInadequate Ca intake is highly prevalent and increased with age in Korean children and adolescents. It should be emphasized to encourage children and adolescents to eat more Ca-rich products to meet their Ca needs.


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