scholarly journals Effects of Omega-3 Fatty Acids on Muscle Mass, Muscle Strength and Muscle Performance among the Elderly: A Meta-Analysis

Nutrients ◽  
2020 ◽  
Vol 12 (12) ◽  
pp. 3739
Author(s):  
Ya-Hui Huang ◽  
Wan-Chun Chiu ◽  
Yuan-Pin Hsu ◽  
Yen-Li Lo ◽  
Yuan-Hung Wang
Keyword(s):  
Fatty Acids ◽  
Muscle Mass ◽  
Walking Speed ◽  
Meta Analysis ◽  
Mass Gain ◽  
The Elderly ◽  
Cochrane Library ◽  
Omega 3 Fatty Acids ◽  
Omega 3

There is increasing evidence showing the role of fatty acids and their derived lipid intermediates in the regulation of skeletal muscle mass synthesis and function. However, the role of omega-3 fatty acids remains unclear. Therefore, we conducted a meta-analysis to evaluate the potential effects of omega-3 fatty acids on sarcopenia-related performances among the elderly. Eligible literature and reports of randomized controlled trials were comprehensively searched from the PubMed, Cochrane Library, ClinicalTrials.gov, and Cumulative Index to Nursing and Allied Health Literature (CINAHL) databases until July 2018. A total of 10 articles were available for the meta-analysis. There were minor benefits for muscle mass gain (0.33 kg; 95% CI: 0.05, 0.62) and timed up and go performance (−0.30 s; 95% CI: −0.43, −0.17). Subgroup analyses regarding muscle mass and walk speed indicated that omega-3 fatty acid supplements at more than 2 g/day may contribute to muscle mass gain (0.67 kg; 95% CI: 0.16, 1.18) and improve walking speed, especially for those receiving more than 6 months of intervention (1.78 m/sec; 95% CI: 1.38, 2.17). Our findings provide some insight into the effects of omega-3 fatty acids on muscle mass, especially for those taking supplements at more than 2 g/day. We also observed that a long period of omega-3 fatty acids supplementation may improve walking speed.

scholarly journals Role of Omega-3 Fatty Acids in the Treatment of Depressive Disorders: A Comprehensive Meta-Analysis of Randomized Clinical Trials

PLoS ONE ◽  
2014 ◽  
Vol 9 (5) ◽  
pp. e96905 ◽  
Author(s):  
Giuseppe Grosso ◽  
Andrzej Pajak ◽  
Stefano Marventano ◽  
Sabrina Castellano ◽  
Fabio Galvano ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Clinical Trials ◽  
Depressive Disorders ◽  
Randomized Clinical Trials ◽  
Meta Analysis ◽  
Omega 3 Fatty Acids ◽  
Omega 3

scholarly journals The Role of Physical Exercise and Omega-3 Fatty Acids in Depressive Illness in the Elderly

2018 ◽  
Vol 16 (3) ◽  
pp. 308-326 ◽  
Author(s):  
Stefano Farioli-Vecchioli ◽  
Stefano Sacchetti ◽  
Nicolis V. di Robilant ◽  
Debora Cutuli
Keyword(s):  
Fatty Acids ◽  
Physical Exercise ◽  
The Elderly ◽  
Depressive Illness ◽  
Omega 3 Fatty Acids ◽  
Omega 3

scholarly journals The Role of Omega-3 Fatty Acids in Acute Pancreatitis: A Meta-Analysis of Randomized Controlled Trials

Nutrients ◽  
2015 ◽  
Vol 7 (4) ◽  
pp. 2261-2273 ◽  
Author(s):  
Qiu Lei ◽  
Xin Wang ◽  
Xian Xia ◽  
Hua Zheng ◽  
Jing Bi ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Acute Pancreatitis ◽  
Randomized Controlled Trials ◽  
Meta Analysis ◽  
Controlled Trials ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Randomized Controlled

scholarly journals Role of omega 3-fatty acids and multivitamins in gestation

2007 ◽  
Vol 35 (s1) ◽  
pp. S19-S24 ◽  
Author(s):  
Irene Hösli ◽  
Rosanna Zanetti-Daellenbach ◽  
Wolfgang Holzgreve ◽  
Olav Lapaire
Keyword(s):  
Fatty Acids ◽  
Observational Studies ◽  
Meta Analysis ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Daily Diet ◽  
Pregnancy And Postpartum ◽  
Maternal Risks ◽  
Global Health Problem

AbstractThere is a rising interest in a balanced and varied women's diet not only preconceptionally but also during pregnancy and in the breastfeeding period in order to reduce fetal, neonatal, and maternal risks. A decreased intake of omega 3-fatty acids (FA) or deficiencies of micronutrients are a global health problem, not only in developing countries, where micronutrient-rich food and fortified aliments are often not available, and also in the industrialized world. In contrast to data about the daily periconceptionally intake of folate acid that has been shown to reduce substantially the occurrence and recurrence of neural tube defects (NTD), the benefit of other micronutrients is less determinant.Deficiencies of omega 3-FA may be a contributing factor for severe complications in pregnancy and postpartum. A meta-analysis for the role of omega 3-FA in preeclampsia and maternal postpartum depression is less consistent, some meta-view's results differ substantially or are even contradictory to large observational studies. Further well-designed studies are warranted. A personal interview and counseling concerning the daily diet should be integrated in the preconceptional and in the antenatal care and an individual supplementation should be offered, if indicated.

scholarly journals Omega-3 fatty acid supplementation is associated with favorable outcomes in patients with sepsis: an updated meta-analysis

2020 ◽  
Vol 48 (12) ◽  
pp. 030006052095368
Author(s):  
Chenyang Wang ◽  
Dong Han ◽  
Xiaojing Feng ◽  
Jing Wu
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Meta Analysis ◽  
Cochrane Library ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Gastrointestinal Dysfunction ◽  
Fatty Acid Supplementation ◽  
Acid Supplementation ◽  
Omega 3 Fatty Acid

Objectives The efficacy of omega-3 fatty acids in the treatment of sepsis is controversial. We conducted an updated meta-analysis to clarify the efficacy of omega-3 fatty acids in patients with sepsis. Methods PubMed, EMBASE, and the Cochrane Library were searched for randomized clinical trials (RCTs) on omega-3 fatty acid supplementation in adults with sepsis. Results Twenty eligible RCTs involving 1514 patients were included in the meta-analysis. Omega-3 fatty acid supplementation was linked to reductions of mortality ( I2 = 0, relative risk [RR] = 0.82, 95% confidence interval [CI] = 0.69–0.97), the duration of mechanical ventilation (DMV; I2 = 74%, weighted mean difference [WMD] = −2.20, 95% CI = −4.00 to −0.40), and intensive care unit (ICU) length of stay (LOS; I2 = 91%, WMD = −3.86, 95% CI = −5.72 to −2.01). Subgroup analysis illustrated that mortality was significantly reduced in patients with sepsis and gastrointestinal dysfunction (RR = 0.5, 95% CI = 0.29–0.86, I2 = 0). Conclusion Omega-3 fatty acid supplementation might be associated with reduced mortality in patients with sepsis, especially those with gastrointestinal dysfunction. Furthermore, omega-3 fatty acid administration could shorten DMV and ICU LOS.

scholarly journals Omega-3 fatty acids in the treatment of acute lung injury: a systematic review and meta-analysis

2019 ◽  
Author(s):  
Caijie Huang ◽  
Jianming Zheng ◽  
Wenzhao Huang ◽  
Meihao Yan ◽  
Liyue Hong ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Acute Lung Injury ◽  
Lung Injury ◽  
Meta Analysis ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Randomized Controlled ◽  
Mean Differences

Abstract Background Several randomized controlled trials (RCTs) have compared the treatment of acute lung injury (ALI) with or without omega-3 fatty acids, yet the results remained inconsistent. Therefore, we attempted this meta-analysis to analyze the role of T Omega-3 fatty acids in the treatment of ALI patients.Methods We searched PubMed et al databases from inception date to Oct 31, 2019 for RCTs that compared the treatment of ALI with or without omega-3 fatty acids. Two authors independently screened the studies and extracted data from the published articles. Summary mean differences (MD) with 95% confidence intervals (CI) were calculated for each outcome by means of fixed- or random-effects model.Results Six RCTs with a total of 277 patients were identified, with 142 with omega-3 fatty acids treatment and 135 without omega-3 fatty acids treatment. Omega-3 fatty acids treatments significantly improve the PaO2 (MD =13.82, 95%CI 8.55– 19.09), PaO2/FiO2 (MD =33.47, 95% CI 24.22– 42.72), total protein (MD =2.02, 95% CI 0.43– 3.62) in ALI patients; furthermore, Omega-3 fatty acids treatments reduced the duration of mechanical ventilation (MD =-1.72, 95% CI -2.84– -0.60) and intensive care unit stay (MD =-1.29, 95% CI -2.14– -0.43) in ALI patients.Conclusions Omega-3 fatty acids can effectively improve the respiratory function and promote the recovery of ALI patients. More studies focused on the long-term efficacy and safety of omega-3 fatty acids use for ALI are needed.

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