scholarly journals Effectiveness of a 6-Month Lifestyle Intervention on Diet, Physical Activity, Quality of Life, and Markers of Cardiometabolic Health in Women with PCOS and Obesity and Non-PCOS Obese Controls: One Size Fits All?

Nutrients ◽  
2021 ◽  
Vol 13 (10) ◽  
pp. 3425
Author(s):  
Zheng Wang ◽  
Henk Groen ◽  
Astrid E. P. Cantineau ◽  
Tessa M. van Elten ◽  
Matty D. A. Karsten ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Physical Activity ◽  
Lifestyle Intervention ◽  
Intervention Program ◽  
Controlled Trial ◽  
Dropout Rate ◽  
Cardiometabolic Health ◽  
Infertile Women ◽  
The Difference

Little is known about the difference in effectiveness of lifestyle intervention between women with PCOS and non-PCOS women. In a post hoc longitudinal analysis of a randomized, controlled trial, we aimed to investigate whether infertile women with PCOS and obesity (N = 87) responded differently to a 6-month lifestyle intervention program than infertile non-PCOS obese controls (N = 172). We evaluated several aspects of the intervention such as changes in diet, physical activity, and dropout rate, as well as the effect on weight, quality of life (QoL), and cardiometabolic outcomes. Multilevel analyses were used, and analyses were adjusted for baseline characteristics such as age, education, and smoking. Although BMI in both groups significantly decreased at 3 months and 6 months, there were no significant differences between the groups at 3 months (adjusted B: −0.3, 95% CI: −0.9 to 0.3, p = 0.35) and 6 months (adjusted B: 0.5, 95% CI: −0.4 to 1.4, p = 0.29). Women with PCOS and non-PCOS women had similar compliance with the lifestyle intervention in terms of actual change in diet and physical activity. Mental QoL scores were not different at either 3 or 6 months. Physical QoL scores were lower in women with PCOS compared with non-PCOS women at 3 months (adjusted B: −2.4, 95% CI: −4.8 to −0.06, p = 0.045) but not at 6 months. Cardiometabolic parameters did not differ between the groups. Our results showed that infertile women with PCOS and obesity and non-PCOS obese controls responded largely similarly to our lifestyle intervention and achieved the same level of improvement in markers of cardiometabolic health.

scholarly journals Effect of a lifestyle intervention in obese infertile women on cardiometabolic health and quality of life: A randomized controlled trial

PLoS ONE ◽  
2018 ◽  
Vol 13 (1) ◽  
pp. e0190662 ◽  
Author(s):  
Lotte van Dammen ◽  
Vincent Wekker ◽  
Anne M. van Oers ◽  
Meike A. Q. Mutsaerts ◽  
Rebecca C. Painter ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Randomized Controlled Trial ◽  
Lifestyle Intervention ◽  
Controlled Trial ◽  
Cardiometabolic Health ◽  
Infertile Women ◽  
Randomized Controlled

Use of a mobile lifestyle intervention application as a waitlist intervention for adolescents with obesity: single arm feasibility study (Preprint)

2020 ◽  
Author(s):  
Chu Shan Elaine Chew ◽  
Eric Andrew Finkelstein ◽  
Courtney Davis
Keyword(s):  
Quality Of Life ◽  
Physical Activity ◽  
Lifestyle Intervention ◽  
Intervention Program ◽  
Clinical Care ◽  
Mobile App ◽  
Z Score ◽  
Fat Percentage ◽  
Lifestyle Intervention Program

BACKGROUND Use of a mobile health tool as a waitlist intervention combined with in-person weight management clinic visits may increase participant engagement and be an effective treatment strategy for adolescent obesity. OBJECTIVE The aim of this study was to assess the effectiveness of and adolescent engagement with a mobile application-based lifestyle intervention program as a waitlist intervention prior to their engagement with a multidisciplinary weight management clinic METHODS This single-arm feasibility study recruited adolescents with obesity, aged 10-16 year old, to a waitlist intervention using a mobile app-based lifestyle intervention program with routine clinical care. Primary outcomes were adolescents’ engagement with the mobile application and BMI z-score at 6 months. Secondary outcomes included health behaviours, physical activity levels , quality of life and disordered eating behaviours. RESULTS We enrolled 40 adolescents with mean age of 13.8 ± 1.7 years and BMI z-score of 2.07 ± 0.30. Participants were ethnically diverse with 45% Chinese, 33% Malay, 15% Indians and 10% of other ethnicity. 83% of the participants had a household income level that was below the national median levels. 83% of the participants engaged with the mobile app-based lifestyle intervention program. There was no significant differences in the BMI z-score and disordered eating behaviours of the participants at 6 months. Participants had significant improvement in quality of life (P=0.044) and physical activity level (P=0.026) with reduction of total caloric intake (P=0.018) and fat percentage (P=0.018) at 6 months. CONCLUSIONS Use of a mobile app-based lifestyle intervention program combined with multidisciplinary clinical care is feasible strategy to provide obesity management services to a low-income and racially diverse Asian population and improves quality of life, physical activity levels and reduces fat percentage and total caloric intake. CLINICALTRIAL ClinicalTrials.gov NCT03561597

Telemedicine intervention efficiency on mobility recovery after bariatric surgery: the MyGoodTrip randomized controlled trial (Preprint)

2020 ◽  
Author(s):  
MAtthieu Bruzzi ◽  
Claire CARETTE ◽  
Katia Lurbe i Puerto ◽  
Tigran Poghosyan ◽  
Marion Bretault ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Physical Activity ◽  
Bariatric Surgery ◽  
Randomized Controlled Trial ◽  
Intervention Program ◽  
Controlled Trial ◽  
Time Frame ◽  
Open Label ◽  
Randomized Controlled

UNSTRUCTURED Our aim was to evaluate a telemedicine intervention program dedicated to the promotion of physical activity including teleconsultation and telemonitoring following bariatric surgery. This study was an open label randomized controlled trial. Patients were included during the first week after bariatric surgery then randomized in two groups of telemedicine intervention: (i) physical coaching focusing on mobility (=TelePhys group) or (ii) dietary coaching (=TeleDiet group). The primary outcome was the difference in the delta number of steps measured during a period of 14 days at the first and sixth postoperative months between the two groups. Data were collected using the connected wireless watch pedometer. Body weight evolution and health-related quality of life were also evaluated. Ninety patients with mean age (SD) 40.6 years (+/-10.3) were included. Seventy-three patients were females (81%) and 62 had gastric bypass (69%). An increase of the mean number of steps between the first and the sixth month was found in both groups but this delta was significant only in the TeleDiet group (p=0.010). No difference was found when comparing the delta between the two intervention groups. A significant increase in quality of life was observed in both groups without any significant differences between the two interventions. Our study was not able to show a significant superiority of a telemedicine intervention dedicated to physical activity in mobility recovery after bariatric surgery. The early postoperative time frame for our intervention may explain our findings. Further research will need to focus on long-term interventions.

scholarly journals Telemedicine Intervention Efficiency on Mobility Recovery After Bariatric Surgery: The MyGoodTrip Randomized Controlled Trial

2020 ◽  
Author(s):  
Mathieu Bruzzi ◽  
Claire Carette ◽  
Katia Lurbe i Puerto ◽  
Tigran Poghosyan ◽  
Marion Bretault ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Physical Activity ◽  
Bariatric Surgery ◽  
Randomized Controlled Trial ◽  
Intervention Program ◽  
Controlled Trial ◽  
Time Frame ◽  
Open Label ◽  
Randomized Controlled

Abstract Background: The use of telemedicine may improve mobility recovery in patients with severe obesity undergoing bariatric surgery. Our aim was to evaluate a telemedicine intervention program dedicated to the promotion of physical activity including teleconsultation and telemonitoring on patients’ number of steps in the six first months following bariatric surgery. Methods: This study was an open label randomized controlled trial. Patients were included during the first week after bariatric surgery. Patients were randomized in two groups of telemedicine intervention: (i) physical coaching focusing on mobility (=TelePhys group) or (ii) dietary coaching (=TeleDiet group). The primary outcome was the difference in the delta number of steps measured during a period of 14 days at the first and sixth postoperative months between the TelePhys and the TeleDiet groups. Data were collected using the connected wireless watch pedometer. Body weight evolution and health-related quality of life were also evaluated. An additional qualitative approach was conducted to evaluate patients’ perception of the connected devices used in the trial.Results: Ninety patients with mean age (SD) 40.6 years (±10.3) were included. Seventy-three patients were females (81.1%) and 62 had gastric bypass (69%). The two intervention groups were comparable at inclusion except for the number of steps significantly higher in the TelePhys group (1073.102 ± 471.102 versus 839.102 ± 437.102, p=0.045). An increase of the mean number of steps between the first and the sixth month was found in both groups but this delta was significant only in the TeleDiet group (p=0.010). No difference was found when comparing the delta between the two intervention groups. A significant increase in quality of life was observed in both groups without any significant differences between the two interventions. Conclusions: Our study was not able to show a significant superiority of a telemedicine intervention dedicated to physical activity in mobility recovery after bariatric surgery. The early postoperative time frame for our intervention may explain the null findings. Further research will need to focus on long-term interventions.Trial registration: This study was registered the 23th of March 2016 (ClinicalTrials.gov Identifier: NCT02716480).

Impact of a 12-month web and smartphone-based intervention initiated during spa therapy to improve long-term physical activity of patients with chronic diseases: randomized controlled trial. (Preprint)

2021 ◽  
Author(s):  
Florie FILLOL ◽  
Ludivine PARIS ◽  
Sébastien PASCAL ◽  
Aurélien MULLIEZ ◽  
Christian-François ROQUES ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Physical Activity ◽  
Waist Circumference ◽  
Controlled Trial ◽  
Intervention Group ◽  
Group Versus ◽  
Control Group ◽  
Spa Therapy

BACKGROUND Lack of physical activity (PA) and sedentary behaviors are leading risk factors for non-communicable diseases (NCD). Web-based interventions are effective in increasing PA in older adults and in NCD patients. In many countries a course of spa therapy is commonly prescribed to NCD patients and represents an ideal context to initiating lifestyle changes. OBJECTIVE The main objective of this study was to evaluate in NCD patients the effectiveness of an intervention combining an individual face-to-face coaching during spa therapy and, when returning home, a web- and smartphone-based PA program including a connected wrist pedometer and a connected weighing scale, on the achievement of physical activity guidelines (PAG) 12 months after the end of spa therapy. METHODS This was a 12-month, prospective, parallel-group, randomized controlled trial. Patients were enrolled during spa therapy and randomized 1:1 to intervention or control group who received usual advices about PA. From the end of spa therapy, PA, weight, waist circumference, and quality of life of the participants in both groups, were assessed by phone every 2 months. Primary outcome was meeting PAG (PA≥600 METs) at 12 months after the end of spa therapy. Secondary outcomes were: meeting current PAG at 6 months of follow-up; sedentary time, weight and waist circumference, PA and quality of life, at 6 and 12 months. Objective use data of the web-and smartphone-based PA program were collected. Analytic methods include intention-to-treat and constrained longitudinal data analyses. RESULTS The study sample was 228 patients (female : 77.2% (176/228), mean age: 62.4 years (SD 6.7), retired: 53.9% (123/228), mean BMI = 28.2 kg.m-2 (SD 4.2)). No group differences were found for any baseline variable. At 12 months, the proportion of patients achieving PAG was significantly higher in intervention group versus control group (81% vs 67% respectively, OR = 2.34 (95% CI 1.02- 5.38; P=.045). No difference between intervention and control group was found neither in achieving PAG at 6 months nor for sedentary time, weight and waist circumference, at 6 and 12 months. Regarding quality of life, the physical component subscale score was significantly higher at 12 months in intervention group versus control group (mean difference: 4.1 (95% CI 1.9-6.3; P<.001). The mean duration use of the program was 7.1 months (SD 4.5). Attrition rate during the first 2 months of the program was 20.4% (23/113) whereas 39.8% (45/113) of the participants used the program for at least 10 months. CONCLUSIONS The results showed significantly more participants meeting PAG at one year in the intervention group compared to controls. A course of spa therapy offers the ideal time and setting to implement education in PA. Digital coaching seems to be more efficient than usual coaching for increasing the level of PA and decreasing sedentariness on the long term. CLINICALTRIAL ClinicalTrials.gov NCT02694796; https://clinicaltrials.gov/ct2/show/NCT02694796.

scholarly journals The Effects of a Preconception Lifestyle Intervention on Childhood Cardiometabolic Health—Follow-Up of a Randomized Controlled Trial

Cells ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 41
Author(s):  
Stijn Mintjens ◽  
Mireille N. M. van Poppel ◽  
Henk Groen ◽  
Annemieke Hoek ◽  
Ben Willem Mol ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Lifestyle Intervention ◽  
Maternal Obesity ◽  
Controlled Trial ◽  
Cardiometabolic Health ◽  
Control Group ◽  
Z Score ◽  
Infertile Women ◽  
Z Scores

Maternal obesity is associated with adverse metabolic outcomes in her offspring, from the earliest stages of development leading to obesity and poorer cardiometabolic health in her offspring. We investigated whether an effective preconception lifestyle intervention in obese women affected cardiometabolic health of their offspring. We randomly allocated 577 infertile women with obesity to a 6-month lifestyle intervention, or to prompt infertility management. Of the 305 eligible children, despite intensive efforts, 17 in the intervention and 29 in the control group were available for follow-up at age 3–6 years. We compared the child’s Body Mass Index (BMI) Z score, waist and hip circumference, body-fat percentage, blood pressure Z scores, pulse wave velocity and serum lipids, glucose and insulin concentrations. Between the intervention and control groups, the mean (±SD) offspring BMI Z score (0.69 (±1.17) vs. 0.62 (±1.04)) and systolic and diastolic blood pressure Z scores (0.45 (±0.65) vs. 0.54 (±0.57); 0.91 (±0.66) vs. 0.96 (±0.57)) were similar, although elevated compared to the norm population. We also did not detect any differences between the groups in the other outcomes. In this study, we could not detect effects of a preconception lifestyle intervention in obese infertile women on the cardiometabolic health of their offspring. Low follow-up rates, perhaps due to the children’s age or the subject matter, combined with selection bias abating contrast in periconceptional weight between participating mothers, hampered the detection of potential effects. Future studies that account for these factors are needed to confirm whether a preconception lifestyle intervention may improve the cardiometabolic health of children of obese mothers.

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