scholarly journals Nativity and Serum Concentrations of Antioxidants in Mexican American Children: A Cross-Sectional Study

Nutrients ◽  
2014 ◽  
Vol 6 (4) ◽  
pp. 1598-1607 ◽  
Author(s):  
Kamal Eldeirawi ◽  
Mary Koenig ◽  
Victoria Persky ◽  
Noel Chavez
Keyword(s):  
Mexican American ◽  
Cross Sectional Study ◽  
Serum Concentrations ◽  
Sectional Study ◽  
Cross Sectional ◽  
American Children

Per- and polyfluoroalkyl substances, epigenetic age and DNA methylation: a cross-sectional study of firefighters

Epigenomics ◽  
2021 ◽  
Author(s):  
Jaclyn M Goodrich ◽  
Miriam M Calkins ◽  
Alberto J Caban-Martinez ◽  
Todd Stueckle ◽  
Casey Grant ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Cross Sectional Study ◽  
Serum Concentrations ◽  
Sectional Study ◽  
Cross Sectional ◽  
Toxicity Biomarkers ◽  
Epigenetic Age ◽  
Polyfluoroalkyl Substances ◽  
Blood Leukocyte ◽  
Epic Array

Background: Per- and polyfluoroalkyl substances (PFASs) are persistent chemicals that firefighters encounter. Epigenetic modifications, including DNA methylation, could serve as PFASs toxicity biomarkers. Methods: With a sample size of 197 firefighters, we quantified the serum concentrations of nine PFASs, blood leukocyte DNA methylation and epigenetic age indicators via the EPIC array. We examined the associations between PFASs with epigenetic age, site- and region-specific DNA methylation, adjusting for confounders. Results: Perfluorohexane sulfonate, perfluorooctanoate (PFOA) and the sum of branched isomers of perfluorooctane sulfonate (Sm-PFOS) were associated with accelerated epigenetic age. Branched PFOA, linear PFOS, perfluorononanoate, perfluorodecanoate and perfluoroundecanoate were associated with differentially methylated loci and regions. Conclusion: PFASs concentrations are associated with accelerated epigenetic age and locus-specific DNA methylation. The implications for PFASs toxicity merit further investigation.

Low serum concentrations of 25-hydroxyvitamin D in young adult Japanese women: a cross sectional study

Nutrition ◽  
2001 ◽  
Vol 17 (11-12) ◽  
pp. 921-925 ◽  
Author(s):  
Kazutoshi Nakamura ◽  
Mitsue Nashimoto ◽  
Shigeki Matsuyama ◽  
Masaharu Yamamoto
Keyword(s):  
Young Adult ◽  
Cross Sectional Study ◽  
Japanese Women ◽  
Serum Concentrations ◽  
Sectional Study ◽  
Cross Sectional ◽  
Hydroxyvitamin D ◽  
25 Hydroxyvitamin D ◽  
Low Serum

Neurocognitive development in 5- to 16-year-old North American children: A cross-sectional study

2013 ◽  
Vol 19 (5) ◽  
pp. 516-539 ◽  
Author(s):  
Marit Korkman ◽  
Pekka Lahti-Nuuttila ◽  
Marja Laasonen ◽  
Sally L. Kemp ◽  
James Holdnack
Keyword(s):  
North American ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Neurocognitive Development ◽  
American Children

scholarly journals P567 Cross-sectional study of the low serum concentrations of testosterone in IBD and the influence on disease activity

2017 ◽  
Vol 11 (suppl_1) ◽  
pp. S369-S369
Author(s):  
T. Hlavaty ◽  
A. Krajcovicova ◽  
J. Kollerova ◽  
T. Koller ◽  
Z. Leskova ◽  
...  
Keyword(s):  
Disease Activity ◽  
Cross Sectional Study ◽  
Serum Concentrations ◽  
Sectional Study ◽  
Cross Sectional ◽  
Low Serum

scholarly journals Is Oxycodone Efficacy Reflected in Serum Concentrations? A Multicenter, Cross-Sectional Study in 456 Adult Cancer Patients

2012 ◽  
Vol 43 (4) ◽  
pp. 694-705 ◽  
Author(s):  
Trine Naalsund Andreassen ◽  
Pål Klepstad ◽  
Andrew Davies ◽  
Kristin Bjordal ◽  
Staffan Lundström ◽  
...  
Keyword(s):  
Cancer Patients ◽  
Cross Sectional Study ◽  
Serum Concentrations ◽  
Sectional Study ◽  
Cross Sectional

scholarly journals Association between vitamin D and fatigue in patients with rheumatoid arthritis: a cross-sectional study

BMJ Open ◽  
2020 ◽  
Vol 10 (2) ◽  
pp. e034935
Author(s):  
Lars Petter Jelsness-Jørgensen ◽  
Lars Grøvle ◽  
Anne Julsrud Haugen
Keyword(s):  
Rheumatoid Arthritis ◽  
Vitamin D ◽  
Psychological Distress ◽  
Disease Activity ◽  
Cross Sectional Study ◽  
Serum Concentrations ◽  
Sectional Study ◽  
Cross Sectional ◽  
Hydroxyvitamin D ◽  
Liquid Chromatography Tandem Mass

ObjectivesIn rheumatoid arthritis (RA), fatigue is an important complaint with a significant impact on quality of life. Vitamin D has modulatory effects on cells of the immune system and may potentially affect RA disease activity and thereby RA-related fatigue. The purpose of this study was to explore associations between fatigue and vitamin D status in patients with RA.DesignHypothesis-generating cross-sectional study.SettingScheduled follow-up visits at a hospital-based general rheumatology clinic.ParticipantsPatients (n=169) with established RA.Primary outcome measures and anlysesFatigue, assessed by the Chalder fatigue questionnaire, and serum concentrations of 25-hydroxyvitamin D (25(OH)D), assessed by liquid chromatography–tandem mass spectrometry. Associations were analysed by correlation, and multivariate linear regression with adjustments for age, sex, body mass index, RA disease activity as measured by the Disease Activity Score 28-joint count C reactive protein (DAS28-CRP), psychological distress, pain and sleep. Fatigue was also compared across four groups based on the levels of serum 25(OH)D with cut points at 30, 50 and 75 nmol/L using one-way analysis of variance.ResultsTwo-thirds of the patients (116/169, 69%) were classified with low RA disease activity, that is, a DAS28-CRP score below 3.2. Their mean (SD) serum 25(OH)D concentration was 56.3 (21.2) nmol/L, with 77 (45.6%) having values below 50 nmol/L and 12 patients (7.1%) below 30 nmol/L. The correlation between fatigue and serum concentrations of 25(OH)D was weak and not statistically significant, r = −0.14 (95% CI: −0.29 to 0.03, p=0.08). In the multivariate model, fatigue was significantly associated with RA disease activity, psychological distress and pain, but not with serum 25(OH)D. Fatigue did not differ across groups with varying levels of serum 25(OH)D.ConclusionThis cross-sectional study found no evidence of association between vitamin D and fatigue in patients with RA.

scholarly journals LIPID PROFILE IN COPD PATIENTS

2021 ◽  
Vol 5 (11) ◽  
Author(s):  
Ramavatar Bairwa ◽  
Pratibha Pareek
Keyword(s):  
Lipid Profile ◽  
Total Cholesterol ◽  
Cholesterol Level ◽  
Serum Cholesterol Level ◽  
Serum Levels ◽  
Cross Sectional Study ◽  
Serum Concentrations ◽  
Sectional Study ◽  
Cross Sectional ◽  
Copd Patients

Background: The COPD patients are expected to have a deranged lipid profile for various reasons like smoking, aging, and using such drugs as steroids. Aims of study to estimate the lipid profile level in COPD patients. Methods: This cross-sectional study was conducted on 50 COPD patients and including 50 control were enrolled in the study. Results: The lipid profile in COPD patients, unpaired t test was performed and it was observed that COPD patients showed significantly higher serum levels of TC, TG, LDL and serum concentrations of HDL were also decreased significantly compared to controls. Conclusion: COPD patients showed significantly higher serum cholesterol level in COPD patients as compared to controls. Keywords: Total cholesterol, TG, COPD.

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