scholarly journals Simultaneous Characterization of Instantaneous Young’s Modulus and Specific Membrane Capacitance of Single Cells Using a Microfluidic System

Sensors ◽  
2015 ◽  
Vol 15 (2) ◽  
pp. 2763-2773 ◽  
Author(s):  
Yang Zhao ◽  
Deyong Chen ◽  
Yana Luo ◽  
Feng Chen ◽  
Xiaoting Zhao ◽  
...  
Keyword(s):  
Young’S Modulus ◽  
Young's Modulus ◽  
Single Cells ◽  
Microfluidic System ◽  
Membrane Capacitance ◽  
Specific Membrane

Crossing constriction channel-based microfluidic cytometry capable of electrically phenotyping large populations of single cells

The Analyst ◽  
2019 ◽  
Vol 144 (3) ◽  
pp. 1008-1015 ◽  
Author(s):  
Yi Zhang ◽  
Yang Zhao ◽  
Deyong Chen ◽  
Ke Wang ◽  
Yuanchen Wei ◽  
...  
Keyword(s):  
High Throughput ◽  
Single Cells ◽  
Microfluidic System ◽  
Membrane Capacitance ◽  
Large Populations ◽  
Specific Membrane

This paper presents a crossing constriction channel-based microfluidic system for high-throughput characterization of specific membrane capacitance (Csm) and cytoplasm conductivity (σcy) of single cells.

scholarly journals Specific membrane capacitance, cytoplasm conductivity and instantaneous Young’s modulus of single tumour cells

2017 ◽  
Vol 4 (1) ◽  
Author(s):  
Ke Wang ◽  
Yang Zhao ◽  
Deyong Chen ◽  
Beiyuan Fan ◽  
Yulan Lu ◽  
...  
Keyword(s):  
Young’S Modulus ◽  
Young's Modulus ◽  
Tumour Cells ◽  
Membrane Capacitance ◽  
Specific Membrane ◽  
Single Tumour

scholarly journals Simultaneously Quantifying Both Young’s Modulus and Specific Membrane Capacitance of Bladder Cancer Cells with Different Metastatic Potential

Micromachines ◽  
2020 ◽  
Vol 11 (3) ◽  
pp. 249
Author(s):  
Na Liu ◽  
Mengying Leng ◽  
Tao Yue ◽  
Liang Dong ◽  
Yuanyuan Liu ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Physical Properties ◽  
Cancer Cells ◽  
Young’S Modulus ◽  
Young's Modulus ◽  
Metastatic Potential ◽  
Membrane Capacitance ◽  
Physical Parameters ◽  
Bladder Cancer Cells ◽  
Specific Membrane

Both Young’s modulus and specific membrane capacitance (SMC) are two important physical parameters for characterizing cell status. In this paper, we utilized a thin-neck-micropipette aspiration system to simultaneously quantify Young’s modulus and SMC value of six types of cell lines in different progression grades, which include four grades from the lowest metastatic potential G1 to the highest potential G4. We investigated how these two physical properties possess heterogeneities in bladder cancer cells with different grades and what roles they might play in grading bladder cancer. The characterization results of these cells of different cancer grades is linearly correlated with the cancer grades, showing that the Young’s modulus is negatively linearly correlated with bladder cancer grades, while SMC shows a positive linear correlation. Furthermore, the combination of these two physical properties on a scatter diagram clearly shows the cell groups with different cancer grades, which means that this combination could be a potential tumor grading marker to identify cancer cells with different metastatic potential.

A constriction channel based microfluidic system enabling continuous characterization of cellular instantaneous Young's modulus

2014 ◽  
Vol 202 ◽  
pp. 1183-1189 ◽  
Author(s):  
Y.N. Luo ◽  
D.Y. Chen ◽  
Y. Zhao ◽  
C. Wei ◽  
X.T. Zhao ◽  
...  
Keyword(s):  
Young’S Modulus ◽  
Young's Modulus ◽  
Microfluidic System

A UNIQUE APPROACH TO EXPERIMENTAL CHARACTERIZATION OF A THERMOSETTING POLYMER MATRIX FOR ICME FRAMEWORKS

2021 ◽  
Author(s):  
MICHAEL N. OLAYA ◽  
SAGAR PATIL ◽  
GREGORY M. ODEGARD ◽  
MARIANNA MAIARÙ
Keyword(s):  
Tensile Strength ◽  
Young’S Modulus ◽  
Young's Modulus ◽  
Cure Kinetics ◽  
Image Correlation ◽  
Scanning Calorimetry ◽  
Mixing Ratios ◽  
Fitting Procedure ◽  
Amine Content

A novel approach for characterization of thermosetting epoxy resins as a function of the degree of cure is presented. Density, cure kinetics, tensile strength, and Young’s modulus are experimentally characterized across four mixing ratios of DGEBF/DETDA epoxy. Dynamic differential scanning calorimetry (DSC) is used to characterize parameters for a Prout-Thompkins kinetic model unique to each mixing ratio case through a data fitting procedure. Tensile strength and Young’s modulus are then characterized using stress-strain data extracted from quasi-static, uniaxial tension tests at room temperature. Strains are measured with the 2-D digital image correlation (DIC) optical strain measurement technique. Strength tends to increase as amine content use in the formulation increases. The converse trend is observed for Young’s modulus. Density measurements also reveal an inverse relationship with amine content.

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