scholarly journals Molecular Imprinting Technology in Quartz Crystal Microbalance (QCM) Sensors

Sensors ◽  
2017 ◽  
Vol 17 (3) ◽  
pp. 454 ◽  
Author(s):  
Sibel Emir Diltemiz ◽  
Rüstem Keçili ◽  
Arzu Ersöz ◽  
Rıdvan Say
2001 ◽  
Vol 435 (1) ◽  
pp. 141-149 ◽  
Author(s):  
Takaomi Kobayashi ◽  
Yasuhiro Murawaki ◽  
Puchalapalli Sreenivasulu Reddy ◽  
Masanori Abe ◽  
Nobuyuki Fujii

2020 ◽  
Vol 840 ◽  
pp. 418-423
Author(s):  
Nur Aisyah Humairah ◽  
Fadlunisa Fadlunisa ◽  
Kiki Amalia Histhiningtyas ◽  
Innas Amaliya Fatyadi ◽  
Roto Roto ◽  
...  

The quartz crystal microbalance (QCM) modified by chitosan/α-pinene, prepared by spin-coating technique has been successfully developed with molecular imprinting polymer (MIP) concept. To remove the template, we carried out two treatments namely heating and vacuum in a desiccator. To find out selectivity of the sensor, the QCM modified with polymer chitosan has been tested with another analyte such as acetone, ethanol, N-amyl alcohol, iso-amyl alcohol. The result shows that chitosan/α-pinene coated QCM sensor can provide a good response as good as sensitivity. The best QCM at heating treatment in a furnace with the decline of frequency is 32 Hz, then the QCM vacuum pumping treatment with decline frequency is 27 Hz.


2009 ◽  
Vol 81 (13) ◽  
pp. 5320-5326 ◽  
Author(s):  
Michael Jenik ◽  
Romana Schirhagl ◽  
Christian Schirk ◽  
Oliver Hayden ◽  
Peter Lieberzeit ◽  
...  

Chemosensors ◽  
2020 ◽  
Vol 8 (3) ◽  
pp. 64
Author(s):  
Usman Latif ◽  
Serpil Can ◽  
Hermann F. Sussitz ◽  
Franz L. Dickert

A molecular imprinting strategy was combined with mass-sensitive transducers to generate robust and reliable biomimetic sensor systems for the detection of bioparticles. The patterning of polymers with bioanalytes enabled us to detect Escherichia coli (E. coli) bacteria with quartz crystal microbalance (QCM). The QCM sensor results were compared with direct Atomic Force Microscopy (AFM) measurements—bacteria cells adhering to the sensor coatings were counted. The recognition sites generated by Bacillus subtilis (B. subtilis) spores could successfully and reversibly recognize the template analyte and ensured rapid sensing. Cross sensitive measurements clearly showed the advantage of the molecular imprinting strategy, by which spores of Bacillus species (subtilis and thuringiensis) could easily be differentiated and selectively detected. The growth of B. subtilis from its spores was observed at 42 °C in appropriate nutrient solution of glucose and ammonium sulfate over a period of 15 h. Moreover, the growth of B. subtilis bacteria from its respective spores was studied by increasing the glucose concentration until saturation effect of the sensor. The polymeric sensor coatings were patterned to fix the B. subtilis in order to investigate osmotic effects according to a frequency response of 400 Hz by altering the ionic strength of 0.1 M.


2021 ◽  
Vol 1023 ◽  
pp. 103-109
Author(s):  
M. Dwiki Destian Susilo ◽  
Teguh Jayadi ◽  
Ahmad Kusumaatmaja ◽  
Ari Dwi Nugraheni

Aflatoxin B1 (AFB1) is one of the mycotoxins with the most dangerous poisons and poses a threat to living things. Several detection methods for Aflatoxin B1 (AFB1) with high sensitivity (LC-MS technique, HPLC, ELISA, etc.) still require lengthy preparation time and are not real-time and portable. Aflatoxin B1 (AFB1) detection is one of the major challenges in the field of food safety because Aflatoxin B1 (AFB1) attacks the food and agricultural products sector. One of the potential sensors that can be used as a base for Aflatoxin B1 (AFB1) detection is the Quartz Crystal Microbalance (QCM) sensor. This study examines the performance of the Quartz Crystal Microbalance (QCM) sensor as one of the Aflatoxin B1 detection techniques through the physical deposition method. The Quartz Crystal Microbalance (QCM) sensor modified uses polyvinyl acetate (PVAc) material as a container to embed a molecular model that will be detected through a molecular imprinting polymer (MIP) process coated on QCM using the electrospinning method. The response results show that the value of the sensor response using the MIP process is more significant than without the MIP process. The sensor characteristics demonstrated by the PVAc/AFB 50 sample have a limit of detection (LOD) value is 0.63 ppb, and a limit of quantitation (LOQ) is 1.91 ppb with a coefficient correlation is 0.97 for testing with a concentration range of 5.0 – 40.0 ppb. Therefore, the MIP process in QCM provides a favorable response for the detection of AFB1 in the future.


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