scholarly journals A “Turn-On” Fluorescence Copper Biosensor Based on DNA Cleavage-Dependent Graphene Oxide-dsDNA-CdTe Quantum Dots Complex

Sensors ◽  
2018 ◽  
Vol 18 (8) ◽  
pp. 2605 ◽  
Author(s):  
Liyun Ding ◽  
Bing Xu ◽  
Tao Li ◽  
Jun Huang ◽  
Wei Bai

A novel “turn-on” fluorescent copper biosensor is developed successfully based on the graphene oxide (GO)-dsDNA-CdTe quantum dots (QDs) complex via chemical crosslink method. The optical and structure properties of GO-dsDNA-CdTe QDs complex are studied by fluorescence (FL) spectra and transmission electron microscopy (TEM) in detail. It is demonstrated that the fluorescence quenching of CdTe QDs is a process of fluorescence resonance energy transfer (FRET) due to the essential surface and quenching properties of two-dimensional GO. Copper ions induce the catalytic reaction of DNA chain and irreversibly break at the cleavage site, which will cause the G-quadruplex formation, moreover further result in the CdTe QDs separated from GO and restored its fluorescence. Therefore, a significant recovery effect on the fluorescence of the GO-dsDNA-CdTe QDs complex is observed in the presence of copper ions. The fluorescence responses are concentration-dependent and can be well described by a linear equation. Compared with other metal ions, the sensor performs good selectivity for copper ions.

2015 ◽  
Vol 39 (8) ◽  
pp. 6092-6098 ◽  
Author(s):  
Yan Li ◽  
Fanping Shi ◽  
Nan Cai ◽  
Xingguang Su

The sandwich method can detect different lectins simply by exchanging the carbohydrates functionalized on the quantum dots and graphene oxide.


Nanoscale ◽  
2019 ◽  
Vol 11 (3) ◽  
pp. 1236-1244 ◽  
Author(s):  
Wenjun He ◽  
Chengbing Qin ◽  
Zhixing Qiao ◽  
Yani Gong ◽  
Xiaorong Zhang ◽  
...  

Fluorescence resonance energy transfer between CdSeTe/ZnS quantum dots and monolayer graphene oxide is in situ manipulated by laser irradiation.


2015 ◽  
Vol 2 (1) ◽  
pp. 60-67 ◽  
Author(s):  
Simanta Kundu ◽  
Santanu Bhattacharyya ◽  
Amitava Patra

The efficient resonance energy transfer from CdTe quantum dots (donors) to Nile Red dye (acceptor) encapsulated PMMA nanoparticles for light harvesting is described.


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