Association of Urinary Bisphenols Concentration with Asthma in Korean Adolescents: Data from the Third Korean National Environmental Health Survey

The effects of bisphenol A (BPA) on asthma have been reported in various in vitro, animal, and human epidemiologic studies. However, epidemiological studies on the effects of bisphenol S (BPS) and bisphenol F (BPF), which are substitutes of BPA, on asthma are lacking. The purpose of this study was to identify the association between BPA, BPS, and BPF and asthma. An asthma-related questionnaire; urinary BPA, BPS, BPF; and the possible confounders were analyzed among 922 adolescents aged 12–17 years who participated in the Korean National Environmental Health Survey 2016. In males, urinary BPA, BPS, and BPF did not show a significant relationship with the lifetime prevalence of asthma. In females, urinary BPS was higher in the asthma group (p < 0.01). High urinary BPS showed a significant relationship with a high odds ratio (OR) of lifetime asthma prevalence in the model adjusted for possible confounders (p < 0.05). High urinary BPS was particularly associated with an increase in the OR of asthma diagnosed after the age of 60 months (p < 0.01). Urinary BPS was significantly associated with asthma diagnosis, especially after the age of 60 months, among Korean adolescent females.

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Association between Urinary Phthalate Metabolite Concentration and Atopic Dermatitis in Korean Adolescents Participating in the Third Korean National Environmental Health Survey, 2015–2017

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph18052261 ◽

2021 ◽

Vol 18 (5) ◽

pp. 2261

Author(s):

Sang-Woo Kim ◽

Jeongho Lee ◽

Soon-Chan Kwon ◽

June-Hee Lee

Keyword(s):

Atopic Dermatitis ◽

Logistic Regression ◽

Environmental Health ◽

Health Survey ◽

Potential Health ◽

Korean Adolescents ◽

The Third ◽

Phthalate Exposure ◽

Phthalate Metabolite ◽

National Environmental

Previous studies have highlighted the potential health effects of phthalate exposure, such as atopic dermatitis and asthma. However, evidence supporting the association between phthalate exposure and atopic dermatitis is limited and based on data collected from Western populations. This study aimed to analyze the association between phthalate exposure and atopic dermatitis in Korean adolescents aged 12–17 years using a nationally representative dataset. We conducted a cross-sectional study using a publicly available dataset from the third Korean National Environmental Health Survey (n = 797). We divided the study participants into four quartiles according to urinary phthalate metabolite concentrations. The odds ratio of having atopic dermatitis was calculated using the first quartile as the reference group in binary logistic regression. We found that in the logistic regression model, both the urinary Mono-(2-ethyl-5-carboxypentyl) phthalate (MECCP; OR: 1.81; CI: 1.01–3.25) and Mono-benzyl phthalate (MBzP; OR: 1.81; CI: 1.01–3.25) concentrations in the highest quartile were positively associated with atopic dermatitis. The atopic dermatitis group had a significantly higher mean urinary MECCP and MBzP concentration. In the future, longitudinal studies involving repeated measurements are warranted to analyze the long-term effects of phthalate.

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Lead, mercury, and cadmium exposures are associated with obesity but not with diabetes mellitus: Korean National Environmental Health Survey (KoNEHS) 2015–2017

Environmental Research ◽

10.1016/j.envres.2021.111888 ◽

2021 ◽

pp. 111888

Author(s):

Min Kyong Moon ◽

Inae Lee ◽

Aram Lee ◽

Hyunwoong Park ◽

Min Joo Kim ◽

...

Keyword(s):

Diabetes Mellitus ◽

Environmental Health ◽

Health Survey ◽

National Environmental

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First nationwide exposure profile of major persistent organic pollutants among Korean adults and their determinants: Korean National Environmental Health Survey Cycle 3 (2015–2017)

International Journal of Hygiene and Environmental Health ◽

10.1016/j.ijheh.2021.113779 ◽

2021 ◽

Vol 236 ◽

pp. 113779

Author(s):

Hye Li Jeon ◽

Sooyeon Hong ◽

Kyungho Choi ◽

Chulwoo Lee ◽

Jiyoung Yoo

Keyword(s):

Environmental Health ◽

Organic Pollutants ◽

Health Survey ◽

Persistent Organic Pollutants ◽

Korean Adults ◽

Exposure Profile ◽

National Environmental

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Urinary levels of phthalate, bisphenol, and paraben and allergic outcomes in children: Korean National Environmental Health Survey 2015–2017

The Science of The Total Environment ◽

10.1016/j.scitotenv.2021.151703 ◽

2021 ◽

pp. 151703

Author(s):

Moonyoung Hwang ◽

Kyungho Choi ◽

Choonghee Park

Keyword(s):

Environmental Health ◽

Health Survey ◽

Urinary Levels ◽

National Environmental

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Association between urinary polycyclic aromatic hydrocarbons and hypertension in the Korean population: data from the Second Korean National Environmental Health Survey (2012–2014)

Scientific Reports ◽

10.1038/s41598-020-74353-w ◽

2020 ◽

Vol 10 (1) ◽

Author(s):

Tae-Woo Lee ◽

Dae Hwan Kim ◽

Ji Young Ryu

Keyword(s):

Cardiovascular Disease ◽

Polycyclic Aromatic Hydrocarbons ◽

Environmental Health ◽

Health Survey ◽

Aromatic Hydrocarbons ◽

Adult Population ◽

Pah Metabolites ◽

Polycyclic Aromatic ◽

Korean Adult ◽

National Environmental

Abstract Polycyclic aromatic hydrocarbons (PAHs) are environmental and occupational pollutants derived from incomplete combustion of organic materials, including wood and fossil fuels. Epidemiological studies have evaluated the association between PAH exposure and hypertension or cardiovascular disease in the general population, but the evidence is limited. In this study, we evaluated the association between urinary PAH metabolites and hypertension in the Korean adult population. A total of 6478 adults who participated in the Second Korean National Environmental Health Survey (2012–2014) were included. The differences in urinary concentrations of four PAH metabolites, including 1-hydroxypyrene, 2-hydroxyfluorene, 1-hydroxyphenanthrene, and 2-naphthol, were compared according to hypertension status using a general linear model. Adjusted odds ratios (aORs) for hypertension were calculated according to the quartile groups of urinary PAH metabolites after adjusting for age, sex, body mass index (BMI), smoking, and alcohol consumption in multiple logistic regression analyses. The estimated mean concentrations of urinary 1-hydroxyphenanthrene were significantly higher in the hypertension group than in the non-hypertension group. In 1-hydroxyphenanthrene, the OR for hypertension was significantly higher in the third and fourth quartile groups than in the first quartile group (third: OR 1.707, 95% CI 1.203–2.423, fourth: OR 1.604, 95% CI 1.158–2.223). No significant associations were detected for the other metabolites. Our results suggest an association between exposure to PAHs and hypertension in a Korean adult population. Further studies are required to evaluate the effects of low-dose long-term exposure to PAHs on hypertension and cardiovascular disease.

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