scholarly journals High Thyroid Cancer Incidence Rate in a Community near a Landfill: A Descriptive Epidemiological Assessment

Toxics ◽  
2021 ◽  
Vol 9 (12) ◽  
pp. 325
Author(s):  
Maaike van Gerwen ◽  
Brandon Gold ◽  
Mathilda Alsen ◽  
Mohemmed N. Khan ◽  
Lauren Petrick ◽  
...  

Background: to investigate the high thyroid cancer incidence rate of Staten Island and to disentangle the effects of potential environmental exposure from a landfill from screening. Methods: age-adjusted thyroid cancer incidence rates obtained from the New York State Public Access Cancer Epidemiology Data for New York State (NYS) excluding New York City (NYC) and the five NYC boroughs, including Staten Island, were mapped over time (1995–2018), investigated per age group and by percentage of localized thyroid cancer. Changes in trends were assessed using joinpoint. Contaminants of concern on Staten Island were assessed for carcinogenic and endocrine disruptive properties. Results: a more pronounced thyroid cancer incidence rate increase, without a difference in age distribution and similar percentages of localized thyroid cancer, was found in Staten Island compared to its demographic equivalent (NYS excluding NYC). Multiple contaminants of concern with carcinogenic and endocrine disrupting properties (e.g., cadmium, lead) were identified in air, water and sediment samples. Conclusion: investigations into the effects of increased/sustained environmental exposures are needed in chronically exposed populations to identify potential mechanisms of action of certain pollutants.

2015 ◽  
Author(s):  
Timothy Conwell ◽  
Francis P Boscoe

We measured urban/rural disparities in cancer incidence in New York State using a data set with more than 500,000 tumors diagnosed among New York State residents between 2008-2012 geocoded to the census tract level. Using poisson regression, we computed the site and stage-specific relative risks of cancer by level of urbanicity after adjustment for age, sex, socioeconomic status and race/ethnicity. 18 of the 23 cancer sites analyzed showed some form of significant association between cancer incidence and urbanicity, although the risk differences were generally small. Differences in risk of 50% or more were seen for stomach, liver, distant-stage uterine, and thyroid cancers (each higher in New York City than in rural areas); esophagus, distant-stage kidney, and distant-stage lung (each lower in New York City than in rural areas); and distant-stage prostate cancer (higher in rural areas).


1992 ◽  
Vol 3 (1) ◽  
pp. 7-15 ◽  
Author(s):  
Philip C. Nasca ◽  
Martin C. Mahoney ◽  
Patricia E. Wolfgang

2015 ◽  
Author(s):  
Timothy Conwell ◽  
Francis P Boscoe

We measured urban/rural disparities in cancer incidence in New York State using a data set with more than 500,000 tumors diagnosed among New York State residents between 2008-2012 geocoded to the census tract level. Using poisson regression, we computed the site and stage-specific relative risks of cancer by level of urbanicity after adjustment for age, sex, socioeconomic status and race/ethnicity. 18 of the 23 cancer sites analyzed showed some form of significant association between cancer incidence and urbanicity, although the risk differences were generally small. Differences in risk of 50% or more were seen for stomach, liver, distant-stage uterine, and thyroid cancers (each higher in New York City than in rural areas); esophagus, distant-stage kidney, and distant-stage lung (each lower in New York City than in rural areas); and distant-stage prostate cancer (higher in rural areas).


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