scholarly journals Botulinum Toxin for the Treatment of Hemifacial Spasm: An Update on Clinical Studies

Toxins ◽  
2021 ◽  
Vol 13 (12) ◽  
pp. 881
Author(s):  
Nicola Tambasco ◽  
Marta Filidei ◽  
Pasquale Nigro ◽  
Lucilla Parnetti ◽  
Simone Simoni
Keyword(s):  
Botulinum Toxin ◽  
Hemifacial Spasm ◽  
Rating Scales ◽  
Spontaneous Recovery ◽  
Poor Quality ◽  
Optimal Timing ◽  
Seventh Cranial Nerve ◽  
Injection Techniques ◽  
The Mean

Hemifacial spasm (HFS) is a movement disorder characterized by involuntary contractions of the facial muscles innervated by the seventh cranial nerve. Generally, it is associated with a poor quality of life due to social embarrassment and can lead to functional blindness. Moreover, it is a chronic condition, and spontaneous recovery is rare. Intramuscular injections of Botulinum Toxin (BoNT) are routinely used as HFS treatment. Methods: We reviewed published articles between 1991 and 2021 regarding the effectiveness and safety of BoNT in HFS as well as any reported differences among BoNT formulations. Results: The efficacy of BoNT for HFS treatment ranged from 73% to 98.4%. The mean duration of the effect was around 12 weeks. Effectiveness did not decrease over time. Adverse effects were usually mild and transient. The efficacy and tolerability of the different preparations appeared to be similar. Among the studies, dosage, injected muscles, intervals of treatment, and rating scales were variable, thus leading to challenges in comparing the results. Conclusions: BoNT was the treatment of choice for HFS due to its efficacy and safety profile. Further studies are needed to investigate the factors that influence the outcome, including the optimal timing of treatment, injection techniques, dosage, and the best selection criteria for formulations.

The Quality Analysis of Hallux Valgus Videos on YouTube

2021 ◽  
Author(s):  
Enes Sari ◽  
Levent FAZLI Umur
Keyword(s):  
Hallux Valgus ◽  
Information Quality ◽  
Statistical Significance ◽  
Poor Quality ◽  
Quality Analysis ◽  
Accurate Information ◽  
Youtube Videos ◽  
The Mean ◽  
The Difference

BACKGROUND:The aim of this study was to evaluate the information quality of YouTube videos on hallux valgus. METHODS:A YouTube search was performed using the keyword 'hallux valgus' to determine the first 300 videos related to hallux valgus. A total of 54 videos met our inclusion criteria and evaluated for information quality by using DISCERN, Journal of the American Medical Association (JAMA) and hallux valgus information assessment (HAVIA) scores. Number of views, time since the upload date, view rate, number of comments, number of likes, number of dislikes, video power index (VPI) values were calculated to determine video popularity. Video length (sec), video source and video content were also noted. The relation between information quality and these factors were statistically evaluated. RESULTS:The mean DISCERN score was 30.35{plus minus}11.56 (poor quality) (14-64), the mean JAMA score was 2.28{plus minus}0.96 (1-4), and the mean HAVIA score was 3.63{plus minus}2.42 (moderate quality) (0.5-8.5). Although videos uploaded by physicians had higher mean DISCERN, JAMA, and HAVIA scores than videos uploaded by non-physicians, the difference was not statistically significant. Additionally, view rates and VPI values were higher for videos uploaded by health channels, but the difference did not reach statistical significance. A statistically significant positive correlation was found between video length and DISCERN (r= 0.294, p= 0.028), and HAVIA scores (r= 0.326, p= 0.015). CONCLUSIONS:This present study demonstrated that the quality of information available on YouTube videos about hallux valgus was low and insufficient. Videos containing accurate information from reliable sources are needed to educate patients on hallux valgus, especially in less frequently mentioned topics such as postoperative complications and healing period.

Effects of botulinum toxin type a on quality of life assessed with the WHOQOL-BREF in hemifacial spasm and blepharospasm

2013 ◽  
Vol 19 (1) ◽  
pp. 12-18 ◽  
Author(s):  
Azize Esra Gürsoy ◽  
Işıl Ugurad ◽  
Gülsen Babacan-Yıldız ◽  
Mehmet Kolukısa ◽  
Arif Çelebi
Keyword(s):  
Quality Of Life ◽  
Botulinum Toxin ◽  
Hemifacial Spasm ◽  
Botulinum Toxin Type A ◽  
Type A ◽  
Botulinum Toxin Type

scholarly journals Evaluating The Quality, Utility And Reliability of Information In Uveitis Videos Shared On YouTube

2021 ◽  
Author(s):  
Burak Tanyıldız ◽  
Murat Oklar
Keyword(s):  
Medical Information ◽  
Poor Quality ◽  
Educational Quality ◽  
Video Content ◽  
Global Quality ◽  
Total View ◽  
The Mean ◽  
Quality And Reliability ◽  
Positive Correlations

Abstract Background: The aim of this study was to analyze the quality of videos on YouTube as educational resources about uveitis.Methods: An online YouTube search was performed using the keyword ‘‘uveitis’’. Total view counts, duration of videos, publishing dates, likes and dislikes, numbers of comments, and source of videos were recorded. Educational quality and accuracy of the video content were evaluated using the DISCERN score, Global Quality Score (GQS), Journal of the American Medical Association (JAMA) score. Video popularity was also evaluated using the video power index (VPI) score. All videos were classified according to publishers and types of categories.Results: From among the 200 videos analyzed, 94 were included. The mean DISCERN score was 38.5 ± 13.2 (poor), the mean JAMA score was 1.8 ± 0.6 (fair), and the GQS was 2.5 ± 0.9 (fair). There were positive correlations between the three checklist (p < .001). VPI was not correlated with each score (p >.05). The most common upload sources were ophthalmologist (24.4%) and YouTube channel (20.2%). Regarding content, 47 videos (50%) medical education, 26 videos (27.6%) patient education, 16 videos (17%) patient experience, 5 videos (5.3%) surgical procedures in patient with uveitis. While the most popular videos were uploaded by doctors other than ophthalmologists, the videos uploaded by academic institutions and associations were found to be higher educational quality and reliability scores. Conclusions: Uveitis videos on YouTube are poor quality and reliability and are not adequately educational for patients. Therefore, the physicians must be aware of the limitations of YouTube and ensure the flow of correct medical information to patients.

scholarly journals Outcome of Injection Botulinum Toxin in Blepharospasm

2021 ◽  
Vol 13 (1) ◽  
pp. 40-49
Author(s):  
Malita Amatya ◽  
Ben Limbu ◽  
Purnima Rajkarnikar ◽  
Hom Bahadur Gurung ◽  
Rohit Saiju
Keyword(s):  
Botulinum Toxin ◽  
Hemifacial Spasm ◽  
Botulinum Toxin Type A ◽  
Botulinum Toxin Type ◽  
Line Treatment ◽  
First Line ◽  
Essential Blepharospasm ◽  
Meige Syndrome ◽  
The Mean ◽  
First Line Treatment

Introduction: Blepharospasm is a condition of involuntary spasm of the orbicularis oculi muscle which leads to intermittent or complete closure of the eyelids. Botulinum toxin is the currently recommended first line treatment for such blepharospasm. This study aims to find out the outcome of injection Botulinum toxin Type A in Blepharospasm. Materials and methods:  It was a hospital based, prospective, interventional study conducted on patients diagnosed as Benign essential blepharospasm (BEB), Meige syndrome (MS) and Hemifacial spasm (HFS) by oculoplastic surgeon at Oculoplasty department OPD, Tilganga Institute of Ophthalmology, from December 2018 to November 2019. After taking all standard precautions for botulinum toxin injections, 6 to 8 sites for injecting 2.5 to 5 IU of the toxin were given. All the patients were evaluated before and after injections according to Jankovic spasm grading and improvement in functional impairment scale and followed on one week, one month, three month and when the symptoms reappeared.  Results: A total of 43 cases which included 32 cases of Benign essential Blepharospasm, 9 Hemifacial spasm and 2 Meige syndrome. The mean Jankovic severity score was 3.51 ± 0.51 (range 3-4). The mean improvement in functional score was 2.60 ± 0.54 (range 1-3), was statistically significant (p-value <0.001).The effective period of injection was 130 ± 20.82 (93 – 189) days.38 patients had repeated injections after reappearance of symptoms. 4 patients had side effects of redness and hematoma at one site.  Conclusion: This study concludes that Botulinum toxin type A is effective in the management of Benign essential blepharospasm, Hemifacial spasm and Meige syndrome. This along with a good safety profile justifies its role as a first line treatment therapy in blepharospasm. However, it is a temporary treatment option where the effect lasts for a short period of time and repeated injections are required.

scholarly journals Evaluation of Youtube Video Content About Developmental Dysplasia of the Hip

2020 ◽  
Author(s):  
Ahmet Oztermeli ◽  
Nazım Karahan
Keyword(s):  
Peer Review Process ◽  
International Health ◽  
Poor Quality ◽  
Developmental Dysplasia ◽  
Global Quality ◽  
Youtube Videos ◽  
The Mean ◽  
Mean Time ◽  
Dysplasia Of The Hip

Abstract Background: The purpose of this study is to investigate the quality and reliability of YouTube videos regarding developmental dysplasia of the hip (DDH).YouTube is one of the most popular websites used as a source of information, but the variety in authorship and lack of a peer-review process are problems.Methods: The search string “developmental dysplasia of the hip” was inputted to the YouTube search engine, and the first 52 videos returned as a response were assessed. The Video Power Index (VPI) (like ratio*view ratio/100) was used to assess the popularity of the videos. Global Quality Score (GQS) and developmental dysplasia of the hip scores (DDHS) were used to evaluate the quality and educational quality of the videos, and The Journal of the American Medical Association Score (JAMAS) was used to evaluate the accuracy of the source of information.Results: According to our research, the mean duration time of the videos was 526 s (SD: 813), and the average view count of the videos was 34,644. The mean time since upload was 1907 days (SD: 1137). On average, the videos received 10.9 comments, 210.3 likes, and 6.8 dislikes. The mean like ratio and VPI were 92.9 (SD: 19.57) and 25.8 (SD: 53.43), respectively. The mean JAMAS, GQS, and DDHS of all videos evaluated were 1.37 (SD: 0.7), 2.46 (SD: 1.09), and 4.63 (SD: 5.00), respectively. The DDHS and GQS were positively correlated (p:0.001 r: 65.8%). The GQS and the DDHS were higher in the academic group than in the commercial group (p:0.01). (p:0.037).Conclusions: The videos regarding DDH on YouTube generally had poor quality. As a result, to maintain an optimal parent–physician or patient–physician relationship, we suggest that international health societies make their own educational videos for parents, patients, and fellow physicians.

scholarly journals Quality and readability of web-based Arabic health information on periodontal disease

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Mohammed Sultan Al-Ak’hali ◽  
Hytham N. Fageeh ◽  
Esam Halboub ◽  
Mohammed Nasser Alhajj ◽  
Zaihan Ariffin
Keyword(s):  
Periodontal Disease ◽  
Health Professional ◽  
Health Information ◽  
Code Of Conduct ◽  
Poor Quality ◽  
Quality Information ◽  
Quality Of Information ◽  
Web Based ◽  
The Mean

Abstract Background Currently, the Internet seems to be a helpful tool for obtaining information about everything that we think about, including diseases, their prevention and treatment approaches. However, doubts exist regarding the quality and readability of such information. This study sought to assess the quality and readability of web-based Arabic information on periodontal disease. Methods In this infodemiological study, the Google, Yahoo!, and Bing search engines were searched using specific Arabic terms on periodontal disease. The first 100 consecutive websites from each engine were obtained. The eligible websites were categorized as commercial, health/professional, journalism, and other. The following tools were applied to assess the quality of the information on the included websites: the Health on the Net Foundation Code of Conduct (HONcode), the Journal of the American Medical Association (JAMA) benchmarks, and the DISCERN tool. The readability was assessed using an online readability tool. Results Of the 300 websites, 89 were eligible for quality and readability analyses. Only two websites (2.3%) were HONcode certified. Based on the DISCERN tool, 43 (48.3%) websites had low scores. The mean score of the JAMA benchmarks was 1.6 ± 1.0, but only 3 (3.4%) websites achieved “yes” responses for all four JAMA criteria. Based on the DISCERN tool, health/professional websites revealed the highest quality of information compared to other website categories. Most of the health/professional websites revealed moderate-quality information, while 55% of the commercial websites, 66% of journalism websites, and 43% of other websites showed poor quality information. Regarding readability, most of the analyzed websites presented simple and readable written content. Conclusions Aside from readable content, Arabic health information on the analyzed websites on periodontal disease is below the required level of quality.

Evaluation of stigmatization in hemifacial spasm and quality of life before and after botulinum toxin treatment

2018 ◽  
Vol 119 (1) ◽  
pp. 55-60 ◽  
Author(s):  
Burcu Yuksel ◽  
Fatma Genc ◽  
Aylin Yaman ◽  
Eylem Ozaydin Goksu ◽  
Pelin Dogan Ak ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Botulinum Toxin ◽  
Hemifacial Spasm ◽  
Before And After ◽  
Botulinum Toxin Treatment

Evaluation of botulinum toxin effects in hemifacial spasm patients: correlation between clinical rating scales and high-speed video system measurements

2020 ◽  
Vol 127 (7) ◽  
pp. 1041-1046
Author(s):  
Tammy H. Osaki ◽  
Midori H. Osaki ◽  
Denny M. Garcia ◽  
Teissy Osaki ◽  
Lilian Ohkawara ◽  
...  
Keyword(s):  
Botulinum Toxin ◽  
Hemifacial Spasm ◽  
High Speed ◽  
Rating Scales ◽  
Video System ◽  
High Speed Video ◽  
Clinical Rating

scholarly journals Frequency of obsessive and compulsive symptoms in patients with blepharospasm and hemifacial spasm

2005 ◽  
Vol 63 (2a) ◽  
pp. 213-216 ◽  
Author(s):  
Renato P. Munhoz ◽  
Helio A.G. Teive ◽  
Marcus V. Della Coletta ◽  
Francisco M.B. Germiniani ◽  
Fábio M. Iwamoto ◽  
...  
Keyword(s):  
Botulinum Toxin ◽  
Facial Nerve ◽  
Psychiatric Disorders ◽  
Hemifacial Spasm ◽  
Structured Interview ◽  
Test Results ◽  
Scale Scores ◽  
Dsm Iv ◽  
The Mean ◽  
Peripheral Origin

BACKGROND: Blepharospasm (BS) is a form of central focal dystonia recently associated with psychiatric disorders, particularly obsessive and compulsive symptoms. Hemifacial spasm (HFS) represents a focal myoclonus with peripheral origin in the facial nerve. OBJECTIVE: To determine the frequency of obsessive and compulsive symptoms in patients with BS in comparison with patients with HFS. METHODS: 30 patients from each group (BS and HFS) followed by the botulinum toxin clinic at the HC-UFPR were evaluated using a structured interview based on the DSM-IV criteria and the Yale-Brown scale. RESULTS: were compared by the mean two-tailed t test. RESULTS: We found obsessive or compulsive symptoms in 20 (66.6%) patients with BE and 21 (70%) with HFS. Yale-Brown scale scores for each group were higher among BS patients; however, diferences were not statisticaly significant. CONCLUSION: Our study did not show a significant diference in the comparison of the prevalence of obsessive and compulsive symptoms among patients with BS and HFS.

An investigation into quality of life improvement in patients undergoing microvascular decompression for hemifacial spasm

2018 ◽  
Vol 128 (1) ◽  
pp. 193-201 ◽  
Author(s):  
Jesse D. Lawrence ◽  
Andrew M. Frederickson ◽  
Yue-Fang Chang ◽  
Patricia M. Weiss ◽  
Peter C. Gerszten ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Systematic Review ◽  
Retrospective Analysis ◽  
Hemifacial Spasm ◽  
Microvascular Decompression ◽  
English Literature ◽  
Meta Analysis ◽  
Complete Recovery ◽  
The Mean

OBJECTIVEHemifacial spasm (HFS) is a movement disorder characterized by involuntary spasms of the facial muscles, and it can negatively impact quality of life (QOL). This retrospective study and systematic review with meta-analysis was conducted to investigate the QOL in patients with HFS following intervention with microvascular decompression (MVD) and botulinum toxin (BT).METHODSIn the retrospective analysis, a QOL questionnaire was administered to all patients undergoing MVD performed by a single surgeon. The QOL questionnaire included unique questions developed based on the authors' experience with HFS patients in addition to the health-related QOL HFS-8 questionnaire. The authors also report on a systematic review of the English literature providing outcomes and complications in patients with HFS undergoing treatment with either MVD or BT.RESULTSRegarding the retrospective analysis, 242 of 331 patients completed the questionnaire. The mean score of the 10 QOL questions improved from 22.78 (SD 9.83) to 2.17 (SD 5.75) following MVD (p < 0.001). There was significant improvement across all subscales of the questionnaire between pre- and postoperative responses (p < 0.001). Regarding the systematic review, it is reported that approximately 90% of patients undergoing MVD for HFS experience a complete recovery from symptoms, whereas the mean peak improvement of symptoms following treatment with BT is 77%. Furthermore, patients undergoing MVD reported a greater improvement in the mean supplemental index of QOL as compared with patients receiving BT therapy.CONCLUSIONSMicrovascular decompression offers a significant improvement in QOL in well-selected patients suffering from HFS, and may offer an increased benefit for QOL over BT injections.

Sign in / Sign up

Export Citation Format

Share Document