Study of changes in the parameters of peripheral blood vessels of the arterial bed during an orthostatic test in hypoxic hypoxia

2021 ◽  
Author(s):  
E.M. Lesova ◽  
V.N. Golubev ◽  
J.N. Korolev
Keyword(s):  
Environmental Factors ◽  
Key Words ◽  
Blood Vessels ◽  
Peripheral Blood ◽  
Vascular Tone ◽  
Lower Leg ◽  
Hypoxic Hypoxia ◽  
Hypoxic Exposure ◽  
Orthostatic Test ◽  
Central Hemodynamics

There were performed studies of reovasography of the lower leg and foot pools to identify possible mechanisms of various reactions from the heart and Central hemodynamics in hypoxia to orthostatic load. The dependence of changes in the parameters of Central hemodynamics in response to various environmental factors on the properties of resistive vessels is shown. Key words: The orthostasis, hypoxic exposure, rheovasography, rheographic index, vascular tone.

scholarly journals Correlation of Circular RNA hsa_circ_0001946, hsa_circ_0125589, and Environmental Factors With Hypertension

2020 ◽  
Vol 33 (11) ◽  
pp. 1047-1047
Author(s):  
Wan-yue Liu ◽  
Yi Sun ◽  
Shu-na Huang ◽  
Yu-zhen Lin ◽  
Hong-yan Guo ◽  
...  
Keyword(s):  
Environmental Factors ◽  
Peripheral Blood ◽  
Circular Rna ◽  
Peripheral Blood Lymphocytes ◽  
Normal Weight ◽  
Circular Rnas ◽  
Blood Leukocytes ◽  
Crossover Analysis ◽  
History Of ◽  
The Relationship

Abstract Background To investigate the main environmental factors of hypertension and the relationship between hypertension and circular RNAs in peripheral blood lymphocytes. Methods This was a case–control study. A total of 681 hypertension patients and 485 subjects without hypertension were recruited between April 2017 and October 2018. All participations completed the questionnaire investigation, physical examination, and laboratory detection. Quantitative real-time polymerase chain reaction was used to analyze circRNAs (hsa_circ_0001946 and hsa_circ_0125589) in peripheral blood leukocytes in 84 hypertensives and 84 controls. Multivariate logistic regression and crossover analysis were used to analyze the interaction and association between environmental factors and circRNAs in hypertension. Results After adjusted by gender, age and marital status, overweight/obesity (odds ratio (OR) = 1.66, 95% confidence interval (CI) 1.24–2.22), abdominal obesity (OR = 2.17, 95% CI 1.54–3.04), anxiety (OR = 2.15, 95% CI 1.41–3.28), family history of hypertension (OR = 4.26, 95% CI 3.18–5.70), and higher levels of hsa_circ_0001946 (OR = 4.13, 95% CI 1.85–9.21) were risk factors for hypertension, while levels of hsa_circ_0125589 were not associated with hypertension. Crossover analysis showed that the risk of hypertension was 13.12 times higher (95% CI 3.89–44.23) in overweight subjects with high hsa_circ_0001946 levels compared with normal weight subjects with low hsa_circ_0001946 levels. Further, the risk of hypertension was 17.78 times higher (95% CI 1.88–168.61) in subjects with anxiety and high hsa_circ_0001946 levels. Conclusions Hypertension is the result of both environmental factors and genetic factors. Higher hsa_circ_0001946 levels, overweight and anxiety may increase the risk of hypertension, while hsa_circ_0125589 levels are not related to hypertension.

A New Calcitonin-Receptor-like Sequence in Rat Pulmonary Blood Vessels

1993 ◽  
Vol 85 (4) ◽  
pp. 385-388 ◽  
Author(s):  
F. Njuki ◽  
C. G. Nicholl ◽  
A. Howard ◽  
J. C. W. Mak ◽  
P. J. Barnes ◽  
...  
Keyword(s):  
Blood Vessels ◽  
Vascular Tone ◽  
Islet Amyloid Polypeptide ◽  
Calcitonin Gene Related Peptide ◽  
Binding Activity ◽  
Calcitonin Receptor ◽  
Islet Amyloid ◽  
Related Peptide ◽  
Calcitonin Gene

1. Two rat clones have been isolated which are similar to known calcitonin-receptor sequences. One of these does not have the distribution expected of a calcitonin receptor. It is widely distributed, with extremely high levels of expression in the lung, where it is associated with the blood vessels. 2. This rat sequence may represent the receptor for calcitonin-gene-related peptide or islet amyloid polypeptide. Both have binding activity in the lung and are potent vasodilators. The gene represented by this sequence may therefore play an important role in the maintenance of vascular tone.

Role of Leukocytes and Endothelial Cells in the Development of Angiogenesis in Inflammation and Wound Healing

2001 ◽  
Vol 125 (1) ◽  
pp. 67-71 ◽  
Author(s):  
Mark W. Lingen
Keyword(s):  
Wound Healing ◽  
Endothelial Cells ◽  
Blood Vessels ◽  
Peripheral Blood ◽  
Inflammatory Process ◽  
Signs And Symptoms ◽  
Critical Component ◽  
Complex Environment ◽  
Seminal Article

Abstract The basic signs and symptoms of inflammation and wound healing have been appreciated for thousands of years. However, the specific cells involved and their roles in this complex environment are still being elucidated today. In 1926, the origin of the phagocytic mononuclear ameboid wandering cell (macrophage) had not been determined. One popular theory was that the cells were differentiated from the endothelial cells of the nearby blood vessels, whereas others believed that the cells came from the peripheral blood or resting wandering cells. The purpose of this article is to review the seminal article published by Lang regarding this topic nearly 75 years ago. In addition, this article will review what is now known with regard to the role of the macrophage and endothelial cells in the development of angiogenesis, which is arguably the most critical component of successful inflammatory process or wound healing.

scholarly journals Autologous Blood Vessels Engineered from Peripheral Blood Sample

2007 ◽  
Vol 45 (1) ◽  
pp. 220
Author(s):  
T. Aper ◽  
A. Schmidt ◽  
M. Duchrow ◽  
H.-P. Bruch
Keyword(s):  
Blood Sample ◽  
Blood Vessels ◽  
Peripheral Blood ◽  
Autologous Blood ◽  
Peripheral Blood Sample

scholarly journals Analysis and Research of Subclinical Diabetic Peripheral Vascular Lesions Based on Mutual Information-based Medical Image Registration Algorithm and Colour Ultrasound Imaging (Preprint)

2020 ◽  
Author(s):  
Nailong Jia ◽  
Long Fan ◽  
Chuanzi Li ◽  
Zhongshi Nie ◽  
Suihuang Wang ◽  
...  
Keyword(s):  
Image Registration ◽  
Mutual Information ◽  
Blood Vessels ◽  
Optimization Algorithm ◽  
Peripheral Blood ◽  
Medical Image ◽  
Hybrid Optimization ◽  
Medical Image Registration ◽  
Hybrid Optimization Algorithm ◽  
Subclinical Diabetes

BACKGROUND Background: At present, the incidence of diabetes is on the rise. When doctors diagnose and treat patients' diseases, they often need to image patients to provide complementary information on patient anatomy and functional metabolism. OBJECTIVE Objective: The aim was to understand the morphological features of peripheral blood vessels of diabetes more accurately and explore its Risk factors for the occurrence of lesions for early diagnosis and early prevention. METHODS Methods: The paper selected subclinical diabetes patients admitted to our hospital from October 2013 to October 2018 as a research object. After performing colour Doppler ultrasonography on peripheral blood vessels, images of ultrasound images were taken. Then the paper proposes a multi-mode medical image registration method based on hybrid optimization algorithm for the multi-extreme problem of mutual information function. Mutual information is used as the similarity measure. The hybrid optimization algorithm is used to search for the best registration exchange parameters. The quasi-colour super images are exchanged for registration purposes. RESULTS Results: The experimental results show that the hybrid optimization algorithm can accurately analyse the colour ultrasound image of the peripheral blood vessels of subclinical diabetes, avoiding falling into the local optimal value, and the accuracy of the registration result reaches the sub-pixel level. CONCLUSIONS Conclusion: With the rapid development of imaging technology, the increasing image resolution, and the increasing amount of image data, parallel performance is high. The quasi-method has a very important significance for multi-modal medical image registration. The parameters in this algorithm can be further optimized. CLINICALTRIAL

Hemodynamic Aspects of Obliterative Processes in Peripheral Blood Vessels—Rigid and Soft Narrowing

1992 ◽  
Vol 114 (2) ◽  
pp. 263-267 ◽  
Author(s):  
S. Einav ◽  
A. Sternberg ◽  
Z. Millo
Keyword(s):  
Blood Vessels ◽  
Peripheral Blood ◽  
Mechanical Model ◽  
Peripheral Resistance ◽  
Flow Characteristics ◽  
Energy Losses ◽  
Pulsed Flow ◽  
Flow Through ◽  
Focal Stenosis

Hemodynamic aspects of obliterative processes in peripheral blood vessels were studied on a mechanical model built of distensible tubing, with a fixed peripheral resistance, through which citrated blood was circulated by pulsatile flow. Hemodynamics of progressive focal stenosis, elongated soft stenosis, and elongated rigid stenosis were assessed. By the use of a hydrodynamic model and a series of in vitro experiments, we have measured the pressure and flow characteristics, and calculated the pressure and energy losses for the various stenotic sites. The critical stricture was found to be larger for a rigid stenosis than a soft stenosis. The length of the stenosis was also an important factor. Increasing the length of a rigid stenosis, for example, by 50 percent resulted in an increase of 25 percent in the flow through the stenosis. The energy dissipation was determined as a preferred indication for several parameters such as: pressure drop, pulsed flow, pulse rate, and the geometry and mechanical properties of the stenosis.

Sign in / Sign up

Export Citation Format

Share Document