Faculty Opinions recommendation of Fibroblast-specific expression of a kinase-deficient type II transforming growth factor beta (TGFbeta) receptor leads to paradoxical activation of TGFbeta signaling pathways with fibrosis in transgenic mice.

Type Ii ◽

Specific Expression ◽

Growth Factor Beta ◽

Tgfbeta Signaling

A 7.1 kbp beta-myosin heavy chain promoter, efficient for green fluorescent protein expression, probably induces lethality when overexpressing a mutated transforming growth factor-beta type II receptor in transgenic mice

Transgenic Research ◽

10.1007/s11248-004-5788-6 ◽

2005 ◽

Vol 14 (1) ◽

pp. 69-80

Author(s):

S�verine Allegra ◽

Lamia Bouazza ◽

Claire Benetollo ◽

Jacques Yuan Li ◽

Dominique Langlois

Keyword(s):

Green Fluorescent Protein ◽

Growth Factor ◽

Transgenic Mice ◽

Green Fluorescent Protein Expression ◽

Fluorescent Protein ◽

Type Ii ◽

Growth Factor Beta ◽

Green Fluorescent

Fibroblast-specific Expression of a Kinase-deficient Type II Transforming Growth Factor β (TGFβ) Receptor Leads to Paradoxical Activation of TGFβ Signaling Pathways with Fibrosis in Transgenic Mice

10.1074/jbc.m300636200 ◽

2003 ◽

Vol 278 (27) ◽

pp. 25109-25119 ◽

Cited By ~ 100

Author(s):

Christopher P. Denton ◽

Bing Zheng ◽

Lowri A. Evans ◽

Xu Shi-wen ◽

Voon H. Ong ◽

...

Keyword(s):

Growth Factor ◽

Transgenic Mice ◽

Signaling Pathways ◽

Transforming Growth Factor Β ◽

Type Ii ◽

Tgfβ Signaling ◽

Specific Expression ◽

Tgfβ Receptor

Cellular distribution of type I and type II receptors for transforming growth factor-beta.

10.1016/s0021-9258(18)67611-2 ◽

1986 ◽

Vol 261 (21) ◽

pp. 9972-9978 ◽

Cited By ~ 7

Author(s):

S Cheifetz ◽

B Like ◽

J Massagué

Keyword(s):

Growth Factor ◽

Cellular Distribution ◽

Type I ◽

Type Ii ◽

Regulation of transglutaminase type II by transforming growth factor-beta 1 in normal and transformed human epidermal keratinocytes.

10.1016/s0021-9258(19)38562-x ◽

1990 ◽

Vol 265 (19) ◽

pp. 11098-11104 ◽

Cited By ~ 1

Author(s):

M D George ◽

T M Vollberg ◽

E E Floyd ◽

J P Stein ◽

A M Jetten

Keyword(s):

Growth Factor ◽

Epidermal Keratinocytes ◽

Type Ii ◽

Human Epidermal Keratinocytes ◽

Expression of transforming growth factor beta type II receptor leads to reduced malignancy in human breast cancer MCF-7 cells

10.1016/s0021-9258(18)47215-8 ◽

1994 ◽

Vol 269 (42) ◽

pp. 26449-26455

Author(s):

L Sun ◽

G Wu ◽

J K Willson ◽

E Zborowska ◽

J Yang ◽

...

Keyword(s):

Breast Cancer ◽

Growth Factor ◽

Human Breast Cancer ◽

Type Ii ◽

Human Breast ◽

Growth Factor Beta ◽

Mcf 7

Formation of hetero-oligomeric complexes of type I and type II receptors for transforming growth factor-beta.

10.1016/s0021-9258(17)32142-7 ◽

1994 ◽

Vol 269 (31) ◽

pp. 20172-20178 ◽

Cited By ~ 2

Author(s):

H. Yamashita ◽

P. ten Dijke ◽

P. Franzén ◽

K. Miyazono ◽

C.H. Heldin

Keyword(s):

Growth Factor ◽

Type I ◽

Type Ii ◽

Hepatic expression of mature transforming growth factor beta 1 in transgenic mice results in multiple tissue lesions.

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.92.7.2572 ◽

1995 ◽

Vol 92 (7) ◽

pp. 2572-2576 ◽

Cited By ~ 445

Author(s):

N. Sanderson ◽

V. Factor ◽

P. Nagy ◽

J. Kopp ◽

P. Kondaiah ◽

...

Keyword(s):

Growth Factor ◽

Transgenic Mice ◽

Hepatic Expression ◽

ABSENCE OF EXPRESSION OF TRANSFORMING GROWTH FACTOR-beta TYPE II RECEPTOR IS ASSOCIATED WITH AN AGGRESSIVE GROWTH PATTERN IN A MURINE RENAL CARCINOMA CELL LINE, RENCA

The Journal of Urology ◽

10.1016/s0022-5347(01)62437-6 ◽

1998 ◽

Vol 160 (5) ◽

pp. 1883-1888 ◽

Cited By ~ 20

Author(s):

SHILAJIT D. KUNDU ◽

ISAAC Y. KIM ◽

DAVID ZELNER ◽

LYNN JANULIS ◽

SHANNON GOODWIN ◽

...

Keyword(s):

Growth Factor ◽

Cell Line ◽

Growth Pattern ◽

Renal Carcinoma ◽

Carcinoma Cell ◽

Type Ii ◽

Growth Factor Beta ◽

Renal Carcinoma Cell Line

Mutation analysis of transforming growth factor beta type II receptor, Smad2, and Smad4 in hepatocellular carcinoma.

International Journal of Oncology ◽

10.3892/ijo.14.1.127 ◽

1999 ◽

Cited By ~ 4

Author(s):

S Kawate ◽

S Takenoshita ◽

S Ohwada ◽

A Mogi ◽

T Fukusato ◽

...

Keyword(s):

Hepatocellular Carcinoma ◽

Growth Factor ◽

Mutation Analysis ◽

Type Ii ◽

Semen Brassicae ameliorates hepatic fibrosis by regulating transforming growth factor-β1/Smad, nuclear factor-κB, and AKT signaling pathways in rats

Drug Design Development and Therapy ◽

10.2147/dddt.s155053 ◽

2018 ◽

Vol Volume 12 ◽

pp. 1205-1213 ◽

Cited By ~ 4

Author(s):

Si Cao ◽

Baoping Zheng ◽

Tao Chen ◽

Xinfeng Chang ◽

Bao Yin ◽

...

Keyword(s):

Growth Factor ◽

Signaling Pathways ◽

Hepatic Fibrosis ◽

Nuclear Factor Kappa B ◽

Akt Signaling ◽

Nuclear Factor ◽

Nuclear Factor Kappa ◽