scholarly journals Semen Brassicae ameliorates hepatic fibrosis by regulating transforming growth factor-β1/Smad, nuclear factor-κB, and AKT signaling pathways in rats

2018 ◽  
Vol Volume 12 ◽  
pp. 1205-1213 ◽  
Author(s):  
Si Cao ◽  
Baoping Zheng ◽  
Tao Chen ◽  
Xinfeng Chang ◽  
Bao Yin ◽  
...  
Keyword(s):  
Growth Factor ◽  
Signaling Pathways ◽  
Hepatic Fibrosis ◽  
Transforming Growth Factor Beta ◽  
Nuclear Factor Kappa B ◽  
Transforming Growth Factor ◽  
Akt Signaling ◽  
Nuclear Factor ◽  
Nuclear Factor Kappa ◽  
Growth Factor Beta

Cellular and molecular mechanisms of chronic rhinosinusitis and potential therapeutic strategies: review on cytokines, nuclear factor kappa B and transforming growth factor beta

2015 ◽  
Vol 129 (S3) ◽  
pp. S2-S7 ◽  
Author(s):  
N T Phan ◽  
P J Cabot ◽  
B D Wallwork ◽  
A U Cervin ◽  
B J Panizza
Keyword(s):  
Growth Factor ◽  
Chronic Rhinosinusitis ◽  
Transforming Growth Factor Beta ◽  
Nuclear Factor Kappa B ◽  
Transforming Growth Factor ◽  
Therapeutic Strategies ◽  
Nuclear Factor ◽  
T Helper ◽  
Nuclear Factor Kappa ◽  
Growth Factor Beta

AbstractBackground:Chronic rhinosinusitis is characterised by persistent inflammation of the sinonasal mucosa. Multiple pathophysiological mechanisms are likely to exist. Previous research has focused predominantly on T-helper type cytokines to highlight the inflammatory mechanisms. However, proteins such as nuclear factor kappa B and transforming growth factor beta are increasingly recognised to have important roles in sinonasal inflammation and tissue remodelling.Objective:This review article explores the roles of T-helper type cytokines, nuclear factor kappa B and transforming growth factor beta in the pathophysiological mechanisms of chronic rhinosinusitis. An understanding of these mechanisms will allow for better identification and classification of chronic rhinosinusitis endotypes, and, ultimately, improved therapeutic strategies.

Interleukin 10 and Transforming Growth Factor Beta 1 in Hepatic Fibrosis

2002 ◽  
Vol 15 (3) ◽  
pp. 243-244 ◽  
Author(s):  
O. Perrella ◽  
M. Perrella ◽  
V. Cusumano ◽  
U. Ibello ◽  
C. Sbreglia ◽  
...  
Keyword(s):  
Growth Factor ◽  
Hepatic Fibrosis ◽  
Transforming Growth Factor Beta ◽  
Transforming Growth Factor ◽  
Interleukin 10 ◽  
Growth Factor Beta
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