Faculty Opinions recommendation of Global tissue revolutions in a morphogenetic movement controlling elongation.

Author(s):  
David Strutt ◽  
Chloe Thomas
1981 ◽  
Vol 87 (2) ◽  
pp. 242-248 ◽  
Author(s):  
K.O. Yanagisawa ◽  
H. Fujimoto ◽  
Hideko Urushihara

Development ◽  
1975 ◽  
Vol 33 (1) ◽  
pp. 227-241
Author(s):  
Jonathan Rubin ◽  
Anthony Robertson

We have extended Raper's original work on the organizing ability of the tip of the Dictyostelium discoideum slug. Our new results are that tips from all multicellular (pseudoplasmodial) stages act as organizers; that the structure organized by a tip depends on the developmental stage of the cells responding to the tip's signal; that tips from all stages release a qualitatively similar signal which is continuous, most probably a gradient of c-AMP; and that the signal from fruiting-body tips appears stronger than that from conus tips. We discuss these results with reference to the control of morphogenetic movement and patterned differentiation and point out that the D. discoideum tip is analagous to a classical organizer, whose signal is interpreted according to the state of determination of cells in its field of influence.


Author(s):  
Mohan Yende ◽  
Sweta Kalmesh Bagate

       In Ayurvedic embryology, various interesting concepts of conception, formation of zygote and foetus and various different organs and system formation are explained. Among that concept of cell division and differentiation in conscious foetus (Chetanayukt Garbha) is mentioned. The role of Panchmahabhutas and Tridoshas in the formation and development of Garbha is mentioned. Among them most important is “Vayu ”which is responsible for cell division .Vayu is vital force which divides zygote into different limb buds and organs. Thus main function of “Vata“ is incomprehensible like formation of foetal shape. But perturbations in “Vata” is responsible for formation of various congenital anomalies i.e Garbhavikruti.          In modern concepts of developmental biology, important area is “Morphogenetic field”. It was first introduced in 1910 by Alexander G. Gurwitsch. He analyzed the embryonic development of the sea urchin as a vector field, As it is the proliferation of cells into organs were brought about by putative external forces. It is the set of process that generates shape and form in the embryo. Morphogenetic movement is caused by large scale and dynamic movement of embryonic cell which is under control of Vata. Failures in any step of process can lead to birth defects.       Ancient Acharyas have mentioned various measures under Garbhini Paricharya for pregnant women from first day of conception  till parturition. It restores the Vayu to its normal course and condition. Thus  it helps the  morphogenetic movement occur without any failure to have healthy foetus and progeny.Thus prevalence of congenital anamolies can be reduced by understanding Vayu as Garbhakrutinam ,Morphogenetic field and following Garbhini paricharya.


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