Faculty Opinions recommendation of Objective hot flashes are negatively related to verbal memory performance in midlife women.

Author(s):  
Henry Burger
Author(s):  
Pauline M. Maki ◽  
Lauren L. Drogos ◽  
Leah H. Rubin ◽  
Suzanne Banuvar ◽  
Lee P. Shulman ◽  
...  

2006 ◽  
Vol 20 (2) ◽  
pp. 68-78 ◽  
Author(s):  
Sibylle Heinze ◽  
Gudrun Sartory ◽  
Bernhard W. Müller ◽  
Armin de Greiff ◽  
Michael Forsting ◽  
...  

Neuroimaging studies have indicated involvement of left prefrontal cortex and temporal areas in verbal memory processes. The current study used event-related functional neuroimaging to compare encoding of subsequently recalled and not recalled words in high and low memory performers. Fifteen healthy volunteers were given lists of words to learn with immediate recall and to read as a control condition. High performers reported to have visualized the words whereas low performers used a rehearsal strategy. Compared to reading, unsuccessful encoding was associated with thalamic and left premotor area (BA 6) activity. Comparing successful with unsuccessful learning yielded widespread activity of the left prefrontal and posterior temporal gyrus as well as the left superior parietal lobe in the whole group. Low performers showed activation of the left premotor area throughout learning and additionally of the left middle temporal and parahippocampal gyrus during successful encoding. High performers showed increased activation in the extrastriate cortex throughout learning and additionally in the left parietal post- and paracentral areas as well as in the right precuneus during successful encoding. The results suggest that high verbal memory performance is the result of spatiovisual activation concomitant to imagery and low performance of hippocampal and motor activation, the latter being associated with rehearsal, with a common memory circuit subserving both groups.


2010 ◽  
Vol 218 (2) ◽  
pp. 135-140 ◽  
Author(s):  
Slawomira J. Diener ◽  
Herta Flor ◽  
Michèle Wessa

Impairments in declarative memory have been reported in posttraumatic stress disorder (PTSD). Fragmentation of explicit trauma-related memory has been assumed to impede the formation of a coherent memorization of the traumatic event and the integration into autobiographic memory. Together with a strong non-declarative memory that connects trauma reminders with a fear response the impairment in declarative memory is thought to be involved in the maintenance of PTSD symptoms. Fourteen PTSD patients, 14 traumatized subjects without PTSD, and 13 non-traumatized healthy controls (HC) were tested with the California Verbal Learning Test (CVLT) to assess verbal declarative memory. PTSD symptoms were assessed with the Clinician Administered PTSD Scale and depression with the Center of Epidemiological Studies Depression Scale. Several indices of the CVLT pointed to an impairment in declarative memory performance in PTSD, but not in traumatized persons without PTSD or HC. No group differences were observed if recall of memory after a time delay was set in relation to initial learning performance. In the PTSD group verbal memory performance correlated significantly with hyperarousal symptoms, after concentration difficulties were accounted for. The present study confirmed previous reports of declarative verbal memory deficits in PTSD. Extending previous results, we propose that learning rather than memory consolidation is impaired in PTSD patients. Furthermore, arousal symptoms may interfere with successful memory formation in PTSD.


2021 ◽  
Vol 197 ◽  
pp. 110891
Author(s):  
Genoa R. Warner ◽  
Diana C. Pacyga ◽  
Rita S. Strakovsky ◽  
Rebecca Smith ◽  
Tamarra James-Todd ◽  
...  

2021 ◽  
pp. 019394592110297
Author(s):  
Graham J. McDougall ◽  
Todd B. Monroe ◽  
Keenan A. Pituch ◽  
Michael A. Carter ◽  
Laurie Abbott

Cultural stereotypes that equate aging with decreased competence and increased forgetfulness have persisted for decades. Stereotype threat (ST) refers to the psychological discomfort people experience when confronted by a negative, self-relevant stereotype in a situation where their behavior could be construed as confirming that belief. The purpose of this study was to examine the relationships of ST on memory performance in older adults over 24 months. The ST levels on average significantly declined, or improved in the memory training, but not the health training group. Although not significant at the .01 level, the bivariate correlation indicated that change in ST was moderately related to change in verbal memory, suggesting the possibility that improvements (or reductions) in ST may be related to increases in verbal memory scores. We discovered that the unique contribution of ST into the memory performance of healthy older adults offers a possible malleable trait.


Author(s):  
Jairo E. Martinez ◽  
Enmanuelle Pardilla-Delgado ◽  
Edmarie Guzmán-Vélez ◽  
Clara Vila-Castelar ◽  
Rebecca Amariglio ◽  
...  

Abstract Objective: Subjective Cognitive Decline (SCD) may be an early indicator of risk for Alzheimer’s disease (AD). Findings regarding sex differences in SCD are inconsistent. Studying sex differences in SCD within cognitively unimpaired individuals with autosomal-dominant AD (ADAD), who will develop dementia, may inform sex-related SCD variations in preclinical AD. We examined sex differences in SCD within cognitively unimpaired mutation carriers from the world’s largest ADAD kindred and sex differences in the relationship between SCD and memory performance. Methods: We included 310 cognitively unimpaired Presenilin-1 (PSEN-1) E280A mutation carriers (51% females) and 1998 noncarrier family members (56% females) in the study. Subjects and their study partners completed SCD questionnaires and the CERAD word list delayed recall test. ANCOVAs were conducted to examine group differences in SCD, sex, and memory performance. In carriers, partial correlations were used to examine associations between SCD and memory performance covarying for education. Results: Females in both groups had greater self-reported and study partner-reported SCD than males (all p < 0.001). In female mutation carriers, greater self-reported (p = 0.02) and study partner-reported SCD (p < 0.001) were associated with worse verbal memory. In male mutation carriers, greater self-reported (p = 0.03), but not study partner-reported SCD (p = 0.11) was associated with worse verbal memory. Conclusions: Study partner-reported SCD may be a stronger indicator of memory decline in females versus males in individuals at risk for developing dementia. Future studies with independent samples and preclinical trials should consider sex differences when recruiting based on SCD criteria.


2016 ◽  
Vol 10 ◽  
Author(s):  
Monika Wilkosc ◽  
Anita Markowska ◽  
Ludmila Zajac-Lamparska ◽  
Maria Skibinska ◽  
Agnieszka Szalkowska ◽  
...  

2013 ◽  
Vol 13 (1) ◽  
Author(s):  
Mahwesh Saleem ◽  
Veera V Ratnam Bandaru ◽  
Nathan Herrmann ◽  
Walter Swardfager ◽  
Michelle M Mielke ◽  
...  

Assessment ◽  
1996 ◽  
Vol 3 (4) ◽  
pp. 403-409 ◽  
Author(s):  
Laurence M. Binder ◽  
Mark P. Kelly

The Portland Digit Recognition Test (PDRT) is a neuropsychological measure of motivation. In an extension of previous work, we report PDRT data on 120 patients with brain dysfunction who had no financial incentives for their performance. Percentile distributions, sensitivity and specificity data, and cognitive and demographic correlates are reported. Age, race, and etiology of brain dysfunction (traumatic or nontraumatic) were unrelated to PDRT performance. Education level was significantly related to PDRT scores. Although IQ and verbal memory performance were related to PDRT scores, the PDRT cutoff scores appear valid for brain dysfunction patients with severe cognitive dysfunction.


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