Faculty Opinions recommendation of Life course body mass index and risk of knee osteoarthritis at the age of 53 years: evidence from the 1946 British birth cohort study.

2012 ◽  
Author(s):  
Ingrid Meulenbelt ◽  
Steffan Daniel Bos
Keyword(s):  
Body Mass Index ◽  
Cohort Study ◽  
Life Course ◽  
Knee Osteoarthritis ◽  
Birth Cohort ◽  
Body Mass ◽  
Birth Cohort Study

scholarly journals Maternal pre-pregnancy body mass index explains infant's weight and BMI at 14 months: results from a multi-ethnic birth cohort study

2009 ◽  
Vol 94 (8) ◽  
pp. 587-595 ◽  
Author(s):  
I Mesman ◽  
T J Roseboom ◽  
G J Bonsel ◽  
R J Gemke ◽  
M F van der Wal ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Cohort Study ◽  
Birth Cohort ◽  
Body Mass ◽  
Birth Cohort Study

scholarly journals Life course body mass index and risk of knee osteoarthritis at the age of 53 years: evidence from the 1946 British birth cohort study

2011 ◽  
Vol 71 (5) ◽  
pp. 655-660 ◽  
Author(s):  
Andrew K Wills ◽  
Stephanie Black ◽  
Rachel Cooper ◽  
Russell J Coppack ◽  
Rebecca Hardy ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Knee Osteoarthritis ◽  
Birth Cohort ◽  
Body Mass ◽  
Prolonged Exposure ◽  
Birth Cohort Study ◽  
Activity Levels ◽  
Z Score ◽  
Knee Oa ◽  
High Bmi

IntroductionThe authors examined how body mass index (BMI) across life is linked to the risk of midlife knee osteoarthritis (OA), testing whether prolonged exposure to high BMI or high BMI at a particular period has the greatest influence on the risk of knee OA.MethodsA population-based British birth cohort of 3035 men and women underwent clinical examination for knee OA at age 53 years.Heights and weights were measured 10 times from 2 to 53 years. Analyses were stratified by gender and adjusted for occupation and activity levels.ResultsThe prevalence of knee OA was higher in women than in men (12.9% (n=194) vs 7.4% (n=108)). In men, the association between BMI and later knee OA was evident at 20 years (p=0.038) and remained until 53 years (OR per z-score 1.38 (95% CI 1.11 to 1.71)). In women, there was evidence for an association at 15 years (p=0.003); at 53 years, the OR was 1.89 (95% CI 1.59 to 2.24) per z-score increase in BMI. Changes in BMI from childhood in women and from adolescence in men were also positively associated with knee OA. A structured modelling approach to disentange the way in which BMI is linked to knee OA suggested that prolonged exposure to high BMI throughout adulthood carried the highest risk and that there was no additional risk conferred from adolescence once adult BMI had been accounted for.ConclusionThis study suggests that the risk of knee OA accumulates from exposure to a high BMI through adulthood.

scholarly journals The association between indoor temperature and body mass index in children: the PIAMA birth cohort study

2013 ◽  
Vol 13 (1) ◽  
Author(s):  
Floor R Scheffers ◽  
Marga BM Bekkers ◽  
Marjan Kerkhof ◽  
Ulrike Gehring ◽  
Gerard H Koppelman ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Cohort Study ◽  
Birth Cohort ◽  
Body Mass ◽  
Birth Cohort Study ◽  
Indoor Temperature
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