scholarly journals Faculty Opinions recommendation of Epithelial cell secretions from the human female reproductive tract inhibit sexually transmitted pathogens and Candida albicans but not Lactobacillus.

2010 ◽  
Author(s):  
Steven Witkin
Keyword(s):  
Candida Albicans ◽  
Epithelial Cell ◽  
Reproductive Tract ◽  
Female Reproductive Tract ◽  
Human Female ◽  
Sexually Transmitted

scholarly journals Adaptation of Neisseria gonorrhoeae to the Female Reproductive Tract

2020 ◽  
Vol 13 ◽  
pp. 117863612094707
Author(s):  
Wenxia Song ◽  
Qian Yu ◽  
Liang-Chun Wang ◽  
Daniel C Stein
Keyword(s):  
Epithelial Cell ◽  
Neisseria Gonorrhoeae ◽  
Reproductive Tract ◽  
Public Health Problem ◽  
Cell Types ◽  
Asymptomatic Infection ◽  
Female Reproductive Tract ◽  
Transmitted Infection ◽  
Sexually Transmitted ◽  
Host Cell Signaling

Gonorrhea, caused by Neisseria gonorrhoeae, is a common sexually transmitted infection and an urgent public health problem. Humans are the exclusive host, and the genital tract with heterogeneous epithelia is the primary niche of this bacterium, creating unique challenges for understanding its pathogenesis. The cervical tissue explant model that we have developed enabled us to show that the properties of the epithelial cells in the female reproductive tract are the main factors driving gonococcal adaptation. Gonococcal variants that colonize strongly and penetrate poorly, thereby causing asymptomatic infection, survive better in the cervix. Gonococci adapt to different epithelial cell types by varying their surfaces and modulating distinct epithelial cell-cell adhesion complexes through manipulation of host cell signaling. These findings provide critical new insights on the mechanisms by which N. gonorrhoeae adapts to the human mucosal surface and causes asymptomatic infection.

Human Female Reproductive Tract Epithelial Cell Culture

2012 ◽  
pp. 347-363 ◽  
Author(s):  
Rachel W. S. Chan ◽  
Abby S. C. Mak ◽  
William S. B. Yeung ◽  
Kai-Fai Lee ◽  
Annie N. Y. Cheung ◽  
...  
Keyword(s):  
Cell Culture ◽  
Epithelial Cell ◽  
Reproductive Tract ◽  
Female Reproductive Tract ◽  
Human Female ◽  
Epithelial Cell Culture

Effect of Contraceptive Steroids on the Endometrium of Guinea Pig: SEM study

1977 ◽  
Vol 35 ◽  
pp. 668-669
Author(s):  
Mai M. Said ◽  
Ramesh K. Nayak ◽  
Randall E. McCoy
Keyword(s):  
Guinea Pig ◽  
Reproductive Tract ◽  
Three Dimensional ◽  
Female Reproductive Tract ◽  
Human Female ◽  
Surface Ultrastructure ◽  
Transmission Electron ◽  
Sem Study ◽  
Uterine Mucosa ◽  
Group 1

Burgos and Wislocki described changes in the mucosa of the guinea pig uterus, cervix and vagina during the estrous cycle investigated by transmission electron microscopy. More recently, Moghissi and Reame reported the effects of progestational agents on the human female reproductive tract. They found drooping and shortening of cilia in norgestrel and norethindrone- treated endometria. To the best of our knowledge, no studies concerning the effects of mestranol and norethindrone given concurrently on the three-dimensional surface features on the uterine mucosa of the guinea pig have been reported. The purpose of this study was to determine the effect of mestranol and norethindrone on surface ultrastructure of guinea pig uterus by SEM.Seventy eight animals were used in this study. They were allocated into two groups. Group 1 (20 animals) was injected intramuscularly 0.1 ml vegetable oil and served as controls.

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