Faculty Opinions recommendation of Clinical value of prognosis gene expression signatures in colorectal cancer: a systematic review.

2013 ◽  
Author(s):  
Yiqian Nancy You ◽  
Brian Keith Bednarski
Keyword(s):  
Gene Expression ◽  
Colorectal Cancer ◽  
Systematic Review ◽  
Clinical Value ◽  
Gene Expression Signatures

scholarly journals Clinical Value of Prognosis Gene Expression Signatures in Colorectal Cancer: A Systematic Review

PLoS ONE ◽  
2012 ◽  
Vol 7 (11) ◽  
pp. e48877 ◽  
Author(s):  
Rebeca Sanz-Pamplona ◽  
Antoni Berenguer ◽  
David Cordero ◽  
Samantha Riccadonna ◽  
Xavier Solé ◽  
...  
Keyword(s):  
Gene Expression ◽  
Colorectal Cancer ◽  
Systematic Review ◽  
Clinical Value ◽  
Gene Expression Signatures

Gene Expression Profiles as Predictors of Poor Outcomes in Stage II Colorectal Cancer: A Systematic Review and Meta-analysis

2009 ◽  
Vol 8 (4) ◽  
pp. 207-214 ◽  
Author(s):  
An-Ting T. Lu ◽  
Shelley R. Salpeter ◽  
Anthony E. Reeve ◽  
Steven Eschrich ◽  
Patrick G. Johnston ◽  
...  
Keyword(s):  
Gene Expression ◽  
Colorectal Cancer ◽  
Systematic Review ◽  
Expression Profiles ◽  
Meta Analysis ◽  
Gene Expression Profiles ◽  
Stage Ii ◽  
Stage Ii Colorectal Cancer ◽  
Poor Outcomes

scholarly journals Gene expression signatures for colorectal cancer microsatellite status and HNPCC

2005 ◽  
Vol 92 (12) ◽  
pp. 2240-2248 ◽  
Author(s):  
M Kruhøffer ◽  
J L Jensen ◽  
P Laiho ◽  
L Dyrskjøt ◽  
R Salovaara ◽  
...  
Keyword(s):  
Gene Expression ◽  
Colorectal Cancer ◽  
Gene Expression Signatures

scholarly journals 454P CCR5/CCL5 gene expression in colorectal cancer (CRC): Comprehensive profiling and clinical value

2021 ◽  
Vol 32 ◽  
pp. S559-S560
Author(s):  
F. Battaglin ◽  
J. Baca ◽  
J. Xiu ◽  
A.F. Shields ◽  
R.M. Goldberg ◽  
...  
Keyword(s):  
Gene Expression ◽  
Colorectal Cancer ◽  
Clinical Value

scholarly journals Exploring Gene Expression Signatures for Predicting Disease Free Survival after Resection of Colorectal Cancer Liver Metastases

PLoS ONE ◽  
2012 ◽  
Vol 7 (11) ◽  
pp. e49442 ◽  
Author(s):  
Nikol Snoeren ◽  
Sander R. van Hooff ◽  
Rene Adam ◽  
Richard van Hillegersberg ◽  
Emile E. Voest ◽  
...  
Keyword(s):  
Gene Expression ◽  
Colorectal Cancer ◽  
Liver Metastases ◽  
Disease Free Survival ◽  
Colorectal Cancer Liver Metastases ◽  
Free Survival ◽  
Gene Expression Signatures ◽  
Disease Free

scholarly journals SELE gene as a characteristic prognostic biomarker of colorectal cancer

2021 ◽  
Vol 49 (4) ◽  
pp. 030006052110043
Author(s):  
Na Li ◽  
Honghe Xiao ◽  
Jiangli Shen ◽  
Ximin Qiao ◽  
Fenjuan Zhang ◽  
...  
Keyword(s):  
Gene Expression ◽  
Colorectal Cancer ◽  
Proportional Hazards ◽  
Cox Regression ◽  
Expression Profiles ◽  
Immunohistochemical Analysis ◽  
Cox Proportional Hazards ◽  
The Cancer Genome Atlas ◽  
Clinical Value ◽  
Cox Regression Analysis

Objective To investigate the expression and clinical value of the E-selectin gene ( SELE) in colorectal cancer (CRC). Methods Using gene expression profiles and clinicopathological data for patients with CRC from The Cancer Genome Atlas, and tumor and adjacent normal tissues from 31 patients with CRC from Xianyang Central Hospital, we studied the correlation between SELE gene expression and clinical parameters using Kaplan–Meier and Cox proportional hazards regression analyses. Results Higher expression of SELE was significantly associated with a poorer prognosis and shorter survival in patients with CRC. The median expression level of SELE was significantly higher in CRC tissues compared with healthy adjacent tissue. Cox regression analysis showed that the prognosis of CRC was significantly correlated with the expression of SELE. Immunohistochemical analysis also showed that positive expression of E-selectin increased significantly in line with increasing TNM stage. Conclusion: This study confirmed that SELE gene expression is an independent prognostic factor in patients with CRC.

Sign in / Sign up

Export Citation Format

Share Document