Faculty Opinions recommendation of Incidence, risk factors and economic burden of fall-related injuries in older Chinese people: a systematic review.

2020 ◽  
Author(s):  
Karel Everaert
Keyword(s):  
Risk Factors ◽  
Systematic Review ◽  
Economic Burden ◽  
Chinese People ◽  
Incidence Risk ◽  
Older Chinese

Incidence, risk factors and economic burden of fall-related injuries in older Chinese people: a systematic review

2019 ◽  
Vol 25 (1) ◽  
pp. 4-12 ◽  
Author(s):  
Ke Peng ◽  
Maoyi Tian ◽  
Melanie Andersen ◽  
Jing Zhang ◽  
Yishu Liu ◽  
...  
Keyword(s):  
Public Health ◽  
Risk Factors ◽  
Economic Burden ◽  
Mainland China ◽  
Service Planning ◽  
Health Concern ◽  
Public Health Issue ◽  
Chinese People ◽  
Incidence Risk ◽  
Older Chinese

ObjectiveChina’s population is ageing and fall-related injury in older Chinese people is a growing public health concern. This review aims to synthesise existing evidence on the incidence, risk factors and economic burden of fall-related injury among older Chinese people to inform health service planning.MethodsA systematic search of literature on falls and injury among older people living in China was performed in six electronic databases including both English and Chinese databases. Results were combined using narrative synthesis due to the heterogeneity of included studies.ResultsA total of 93 studies from Mainland China, Taiwan and Hong Kong were included in this review. Most of these studies were descriptive; 82 reported the incidence of fall-related injury among older Chinese people, 7 studies examined the risk factors for fall-related injury and 22 studies described the economic burden of fall-related injury. The incidence of fall-related injury reported among older Chinese people ranged from 0.6% to 19.5%. Risk factors significantly associated with fall-related injury among older Chinese included older age, female sex, walking aid use, living environments, chronic disease, medication usage, visual impairment and a fall direction other than forward. The cost of fall-related injury among older Chinese people ranged from US$16 to US$3812 per person per fall.ConclusionFalls-related injuries are a significant public health issue for older Chinese people. Further studies using prospective design to identify risk factors and the economic burden of fall-related injuries are needed.

scholarly journals Incidence, risk factors and prognostic effect of imaging right ventricular involvement in patients with COVID-19: a dose–response analysis protocol for systematic review

BMJ Open ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. e049866
Author(s):  
Chenghui Zhou ◽  
Baohui Lou ◽  
Hui Li ◽  
Xin Wang ◽  
Hushan Ao ◽  
...  
Keyword(s):  
Risk Factors ◽  
Systematic Review ◽  
Right Ventricular ◽  
Dose Response ◽  
Meta Analysis ◽  
Adult Patients ◽  
Sensitivity Analyses ◽  
Prognostic Effect ◽  
All Cause Mortality ◽  
Incidence Risk

IntroductionEmerging evidence has shown that COVID-19 infection may result in right ventricular (RV) disturbance and be associated with adverse clinical outcomes. The aim of this meta-analysis is to summarise the incidence, risk factors and the prognostic effect of imaging RV involvement in adult patients with COVID-19.MethodsA systematical search will be performed in PubMed, EMBase, ISI Knowledge via Web of Science and preprint databases (MedRxiv and BioRxiv) (until October 2021) to identify all cohort studies in adult patients with COVID-19. The primary outcome will be the incidence of RV involvement (dysfunction and/or dilation) assessed by echocardiography, CT or MRI. Secondary outcomes will include the risk factors for RV involvement and their association with all-cause mortality during hospitalisation. Additional outcomes will include the RV global or free wall longitudinal strain (RV-GLS or RV-FWLS), tricuspid annular plane systolic excursion (TAPSE), fractional area change (FAC) and RV diameter. Univariable or multivariable meta-regression and subgroup analyses will be performed for the study design and patient characteristics (especially acute or chronic pulmonary embolism and pulmonary hypertension). Sensitivity analyses will be used to assess the robustness of our results by removing each included study at one time to obtain and evaluate the remaining overall estimates of RV involvement incidence and related risk factors, association with all-cause mortality, and other RV parameters (RV-GLS or RV-FWLS, TAPSE, S’, FAC and RV diameter). Both linear and cubic spline regression models will be used to explore the dose–response relationship between different categories (>2) of RV involvement and the risk of mortality (OR or HR).Ethics and disseminationThere was no need for ethics approval for the systematic review protocol according to the Institutional Review Board/Independent Ethics Committee of Fuwai Hospital. This meta-analysis will be disseminated through a peer-reviewed journal for publication.PROSPERO registration numberCRD42021231689.

scholarly journals Systematic review: Incidence, risk factors, survival and treatment of bone metastases from colorectal cancer

2018 ◽  
Vol 13 ◽  
pp. 97-105 ◽  
Author(s):  
Troels Dreier Christensen ◽  
Sandra Galinska Jensen ◽  
Finn Ole Larsen ◽  
Dorte Lisbet Nielsen
Keyword(s):  
Colorectal Cancer ◽  
Risk Factors ◽  
Systematic Review ◽  
Bone Metastases ◽  
Incidence Risk

scholarly journals 2426. Ceftaroline-Associated Neutropenia: Retrospective Study and Systematic Review of Incidence, Risk Factors, and Outcomes

2018 ◽  
Vol 5 (suppl_1) ◽  
pp. S725-S725
Author(s):  
Eva Sullivan ◽  
Hollis O’neal ◽  
R Brigg Turner ◽  
Nancy Crum-Cianflone
Keyword(s):  
Risk Factors ◽  
Systematic Review ◽  
Retrospective Study ◽  
Incidence Risk

scholarly journals High Visceral Fat Area Attenuated the Negative Association between High Body Mass Index and Sarcopenia in Community-Dwelling Older Chinese People

Healthcare ◽  
2020 ◽  
Vol 8 (4) ◽  
pp. 479
Author(s):  
Cheng Li ◽  
Bingxian Kang ◽  
Ting Zhang ◽  
Hongru Gu ◽  
Qingqing Man ◽  
...  
Keyword(s):  
Risk Factors ◽  
Muscle Mass ◽  
Negative Association ◽  
Community Dwelling ◽  
Metabolic Risk ◽  
Chinese People ◽  
Visceral Fat Area ◽  
Negatively Associated ◽  
Older Chinese ◽  
High Bmi

The association between obesity and sarcopenia remains controversial. The present study was conducted to explore the associations among body mass index (BMI), visceral fat area (VFA), and sarcopenia in older people and analyze their potential mechanisms. This cross-sectional study included 861 community-dwelling older Chinese people from three regions of China. BMI, VFA, muscle mass, muscle strength, physical performance, body composition, and metabolic markers were measured. Muscle mass and muscle strength were positively correlated with BMI, but were negatively correlated with VFA. Simple overweight/obesity was negatively associated with sarcopenia (OR = 0.07, 95% CI = 0.03~0.18), and the OR value was lower than combined obesity (OR = 0.16, 95% CI = 0.09~0.28). Fat free mass and total body protein were positively associated with high BMI but negatively associated with high VFA. Furthermore, high VFA was adversely associated with some metabolic risk factors of sarcopenia. Combination of BMI and VFA increased diagnostic efficiency of low muscle mass and sarcopenia. In conclusion, high BMI was negatively associated with sarcopenia, while high VFA attenuated the negative association between high BMI and sarcopenia. The opposite association may partially be attributed to their different associations with body composition and metabolic risk factors of sarcopenia. Therefore, bedsides BMI, VFA and its interaction with BMI should be considered in sarcopenia prevention.

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