Hamstrings injury incidence, risk factors, and prevention in Rugby Union players: A systematic review

IntroductionEmerging evidence has shown that COVID-19 infection may result in right ventricular (RV) disturbance and be associated with adverse clinical outcomes. The aim of this meta-analysis is to summarise the incidence, risk factors and the prognostic effect of imaging RV involvement in adult patients with COVID-19.MethodsA systematical search will be performed in PubMed, EMBase, ISI Knowledge via Web of Science and preprint databases (MedRxiv and BioRxiv) (until October 2021) to identify all cohort studies in adult patients with COVID-19. The primary outcome will be the incidence of RV involvement (dysfunction and/or dilation) assessed by echocardiography, CT or MRI. Secondary outcomes will include the risk factors for RV involvement and their association with all-cause mortality during hospitalisation. Additional outcomes will include the RV global or free wall longitudinal strain (RV-GLS or RV-FWLS), tricuspid annular plane systolic excursion (TAPSE), fractional area change (FAC) and RV diameter. Univariable or multivariable meta-regression and subgroup analyses will be performed for the study design and patient characteristics (especially acute or chronic pulmonary embolism and pulmonary hypertension). Sensitivity analyses will be used to assess the robustness of our results by removing each included study at one time to obtain and evaluate the remaining overall estimates of RV involvement incidence and related risk factors, association with all-cause mortality, and other RV parameters (RV-GLS or RV-FWLS, TAPSE, S’, FAC and RV diameter). Both linear and cubic spline regression models will be used to explore the dose–response relationship between different categories (>2) of RV involvement and the risk of mortality (OR or HR).Ethics and disseminationThere was no need for ethics approval for the systematic review protocol according to the Institutional Review Board/Independent Ethics Committee of Fuwai Hospital. This meta-analysis will be disseminated through a peer-reviewed journal for publication.PROSPERO registration numberCRD42021231689.

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Trail running injury risk factors: a living systematic review

British Journal of Sports Medicine ◽

10.1136/bjsports-2021-104858 ◽

2022 ◽

pp. bjsports-2021-104858

Author(s):

Carel Viljoen ◽

Dina C (Christa) Janse van Rensburg ◽

Willem van Mechelen ◽

Evert Verhagen ◽

Bruno Silva ◽

...

Keyword(s):

Risk Factors ◽

Systematic Review ◽

Injury Risk ◽

Previous History ◽

Future Research ◽

Injury Incidence ◽

Extrinsic Factors ◽

Factors Associated ◽

Injury Risk Factors ◽

Trail Running

ObjectiveTo review and frequently update the available evidence on injury risk factors and epidemiology of injury in trail running.DesignLiving systematic review. Updated searches will be done every 6 months for a minimum period of 5 years.Data sourcesEight electronic databases were searched from inception to 18 March 2021.Eligibility criteriaStudies that investigated injury risk factors and/or reported the epidemiology of injury in trail running.ResultsNineteen eligible studies were included, of which 10 studies investigated injury risk factors among 2 785 participants. Significant intrinsic factors associated with injury are: more running experience, level A runner and higher total propensity to sports accident questionnaire (PAD-22) score. Previous history of cramping and postrace biomarkers of muscle damage is associated with cramping. Younger age and low skin phototypes are associated with sunburn. Significant extrinsic factors associated with injury are neglecting warm-up, no specialised running plan, training on asphalt, double training sessions per day and physical labour occupations. A slower race finishing time is associated with cramping, while more than 3 hours of training per day, shade as the primary mode of sun protection and being single are associated with sunburn. An injury incidence range 0.7–61.2 injuries/1000 hours of running and prevalence range 1.3% to 90% were reported. The lower limb was the most reported region of injury, specifically involving blisters of the foot/toe.ConclusionLimited studies investigated injury risk factors in trail running. Our review found eight intrinsic and nine extrinsic injury risk factors. This review highlighted areas for future research that may aid in designing injury risk management strategies for safer trail running participation.PROSPERO registration numberCRD42021240832.

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Incidence, risk factors and treatment of cervical stenosis after radical trachelectomy: A systematic review

European Journal of Cancer ◽

10.1016/j.ejca.2015.05.012 ◽

2015 ◽

Vol 51 (13) ◽

pp. 1751-1759 ◽

Cited By ~ 24

Author(s):

Xiaoqi Li ◽

Jin Li ◽

Xiaohua Wu

Keyword(s):

Risk Factors ◽

Systematic Review ◽

Cervical Stenosis ◽

Radical Trachelectomy ◽

Incidence Risk

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Incidence, risk factors and outcomes of new-onset atrial fibrillation in patients with sepsis: a systematic review

Critical Care ◽

10.1186/s13054-014-0688-5 ◽

2014 ◽

Vol 18 (6) ◽

Cited By ~ 78

Author(s):

Sanne Kuipers ◽

Peter MC Klein Klouwenberg ◽

Olaf L Cremer

Keyword(s):

Risk Factors ◽

Atrial Fibrillation ◽

Systematic Review ◽

Incidence Risk ◽

Onset Atrial Fibrillation ◽

New Onset

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COVID-19-related acute kidney injury; incidence, risk factors and outcomes in a large UK cohort

BMC Nephrology ◽

10.1186/s12882-021-02557-x ◽

2021 ◽

Vol 22 (1) ◽

Author(s):

Paul D. Jewell ◽

Kate Bramham ◽

James Galloway ◽

Frank Post ◽

Sam Norton ◽

...

Keyword(s):

Risk Factors ◽

Acute Kidney Injury ◽

Renal Impairment ◽

Strong Predictor ◽

Kidney Injury ◽

Injury Incidence ◽

Tertiary Centre ◽

Incidence Risk ◽

Stage 1 ◽

Worse Prognosis

Abstract Background Acute kidney injury (AKI) is common among patients hospitalised with COVID-19 and associated with worse prognosis. The aim of this study was to investigate the epidemiology, risk factors and outcomes of AKI in patients with COVID-19 in a large UK tertiary centre. Methods We analysed data of consecutive adults admitted with a laboratory-confirmed diagnosis of COVID-19 across two sites of a hospital in London, UK, from 1st January to 13th May 2020. Results Of the 1248 inpatients included, 487 (39%) experienced AKI (51% stage 1, 13% stage 2, and 36% stage 3). The weekly AKI incidence rate gradually increased to peak at week 5 (3.12 cases/100 patient-days), before reducing to its nadir (0.83 cases/100 patient-days) at the end the study period (week 10). Among AKI survivors, 84.0% had recovered renal function to pre-admission levels before discharge and none required on-going renal replacement therapy (RRT). Pre-existing renal impairment [odds ratio (OR) 3.05, 95%CI 2.24–4,18; p < 0.0001], and inpatient diuretic use (OR 1.79, 95%CI 1.27–2.53; p < 0.005) were independently associated with a higher risk for AKI. AKI was a strong predictor of 30-day mortality with an increasing risk across AKI stages [adjusted hazard ratio (HR) 1.59 (95%CI 1.19–2.13) for stage 1; p < 0.005, 2.71(95%CI 1.82–4.05); p < 0.001for stage 2 and 2.99 (95%CI 2.17–4.11); p < 0.001for stage 3]. One third of AKI3 survivors (30.7%), had newly established renal impairment at 3 to 6 months. Conclusions This large UK cohort demonstrated a high AKI incidence and was associated with increased mortality even at stage 1. Inpatient diuretic use was linked to a higher AKI risk. One third of survivors with AKI3 exhibited newly established renal impairment already at 3–6 months.

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