scholarly journals Faculty Opinions recommendation of Genome-wide association analysis of venous thromboembolism identifies new risk loci and genetic overlap with arterial vascular disease.

Author(s):  
Karl C Desch
2021 ◽  
Author(s):  
Shahram Bahrami ◽  
Kaja Nordengen ◽  
Alexey A. Shadrin ◽  
Oleksandr Frei ◽  
Dennis van der Meer ◽  
...  

Despite its major role in complex human behaviours across the lifespan, including memory formation and decline, navigation and emotions, much of the genetic architecture of the hippocampal formation is currently unexplored. Here, through multivariate genome-wide association analysis in volumetric data from 35,411 individuals, we revealed 173 unique genetic loci with distributed associations across the hippocampal formation. We identified profound genetic overlap with eight major developmental and degenerative brain disorders, where common genes suggest partly age- and disorder-independent mechanisms underlying hippocampal pathology.


2017 ◽  
Vol 49 (11) ◽  
pp. 1584-1592 ◽  
Author(s):  
Anke R Hammerschlag ◽  
Sven Stringer ◽  
Christiaan A de Leeuw ◽  
Suzanne Sniekers ◽  
Erdogan Taskesen ◽  
...  

A comment on Zhao J, Yang Y, Huang H, Li D, Gu D, Lu X, et al. Association of ABO blood group and Covid19 susceptability. medRxiv [PREPRINT]. 2020; https://doi.org/10.1101/2020.03.11.20031096. Zeng X, Fan H, Lu D, Huang F, Meng X, Li Z, et al. Association between ABO blood group and clinical outcomes of Covid19. medRxiv[PREPRINT].2020; https://doi.org/10.1101/2020.04.15.20063107. Zietz M, Tatonetti N. Testing the association between blood type and COVID-19 infection, intubation, and death medRxiv [PREPRINT]. 2020; https://doi.org/10.1101/2020.04.08.20058073. Ellinghaus D, Degenhardt F, Bujanda L, al. e. The ABO blood group and a chromosome 3 gene cluster associate with SRAS-CoV2 respitarory failure in an Italy-Spain genome-wide association analysis. medRxiv. 2020; https://doi.org/10.1101/2020.05.31.20114991.


2014 ◽  
Vol 40 (1) ◽  
pp. 1 ◽  
Author(s):  
Huan-Xin ZHANG ◽  
Jian-Feng WENG ◽  
Xiao-Cong ZHANG ◽  
Chang-Lin LIU ◽  
Hong-Jun YONG ◽  
...  

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