Faculty Opinions recommendation of Psychedelics, but Not Ketamine, Produce Persistent Antidepressant-like Effects in a Rodent Experimental System for the Study of Depression.

Author(s):  
Dave Nichols
Keyword(s):  
2019 ◽  
Vol 35 (1) ◽  
pp. 126-136 ◽  
Author(s):  
Tour Liu ◽  
Tian Lan ◽  
Tao Xin

Abstract. Random response is a very common aberrant response behavior in personality tests and may negatively affect the reliability, validity, or other analytical aspects of psychological assessment. Typically, researchers use a single person-fit index to identify random responses. This study recommends a three-step person-fit analysis procedure. Unlike the typical single person-fit methods, the three-step procedure identifies both global misfit and local misfit individuals using different person-fit indices. This procedure was able to identify more local misfit individuals than single-index method, and a graphical method was used to visualize those particular items in which random response behaviors appear. This method may be useful to researchers in that it will provide them with more information about response behaviors, allowing better evaluation of scale administration and development of more plausible explanations. Real data were used in this study instead of simulation data. In order to create real random responses, an experimental test administration was designed. Four different random response samples were produced using this experimental system.


1968 ◽  
Vol 19 (03/04) ◽  
pp. 526-532 ◽  
Author(s):  
L. B Nanninga ◽  
M. M Guest

SummaryThe purified anticoagulant split product of fibrinogen has antifibrinolytic and anti-fibrinogenolytic activity. This was investigated by lysis times of fibrin and by the rate of disappearance of fibrinogen in plasma and in a purified system. A new method was used to measure fibrinogenolytic activity. In the experimental system which we have used no indication of additional breakdown of the anticoagulant split product in the presence of fibrinolysin was obtained.


1971 ◽  
Vol 68 (1_Suppl) ◽  
pp. S223-S246 ◽  
Author(s):  
C. R. Wira ◽  
H. Rochefort ◽  
E. E. Baulieu

ABSTRACT The definition of a RECEPTOR* in terms of a receptive site, an executive site and a coupling mechanism, is followed by a general consideration of four binding criteria, which include hormone specificity, tissue specificity, high affinity and saturation, essential for distinguishing between specific and nonspecific binding. Experimental approaches are proposed for choosing an experimental system (either organized or soluble) and detecting the presence of protein binding sites. Techniques are then presented for evaluating the specific protein binding sites (receptors) in terms of the four criteria. This is followed by a brief consideration of how receptors may be located in cells and characterized when extracted. Finally various examples of oestrogen, androgen, progestagen, glucocorticoid and mineralocorticoid binding to their respective target tissues are presented, to illustrate how researchers have identified specific corticoid and mineralocorticoid binding in their respective target tissue receptors.


Author(s):  
Erinda Piluri ◽  
◽  
Hasime Manaj ◽  
Ilirjan Malollari ◽  
Irakli Premti ◽  
...  

2000 ◽  
Vol 41 (1) ◽  
pp. 69-72 ◽  
Author(s):  
S.Ç. Ayaz ◽  
I. Akca

The constructed wetland is a low-cost technology to control environmental pollution. The system is especially suitable for small settlements. An innovative constructed wetland technology is described in this paper. A pilot plant was used to assess the performance of the system. The experimental system consists of two serial connected tanks that settled up with fillers and Cyperus as treatment media. Wastewater is recycled periodically upward and downward between the two tanks. The treatment performance was monitored in different loading conditions in a one-year period. The average COD removal efficiency of 90% was observed at 122 g COD/m2.day average loading conditions. Other average removal values in the same conditions are as follows: suspended solid 95%, TKN 77%, total nitrogen 61%, PO4-P 39%. The land requirement for this system will be 0.82 m2 per capita when applying as full-scale system.


1995 ◽  
Vol 60 (12) ◽  
pp. 2074-2084
Author(s):  
Petr Mikulášek

The microfiltration of a model fluid on an α-alumina microfiltration tubular membrane in the presence of a fluidized bed has been examined. Following the description of the basic characteristic of alumina tubular membranes, model dispersion and spherical particles used, some comments on the experimental system and experimental results for different microfiltration systems are presented. From the analysis of experimental results it may be concluded that the use of turbulence-promoting agents resulted in a significant increase of permeate flux through the membrane. It was found out that the optimum porosity of fluidized bed for which the maximum values of permeate flux were reached is approximately 0.8.


2020 ◽  
Vol 1550 ◽  
pp. 032078
Author(s):  
Kaigang Fan ◽  
Xin Chen ◽  
Biao Zhao ◽  
Jiale Wang ◽  
Wenbin Cui ◽  
...  

2010 ◽  
Vol 152-153 ◽  
pp. 164-170
Author(s):  
Jie Liu ◽  
Jian Lin Li ◽  
Ying Xia Li ◽  
Shan Shan Yang ◽  
Ji Fang Zhou ◽  
...  

Specific to the improvement in the present research of mechanical response under cyclic loading, this paper, taking the calcareous middle- coarse sandstone as the research subject and the RMT-150C experimental system in which data is recoded by ms magnitude as the platform, develops several related models concerning the unloading rate of triangle waves. The unloading process is divided into lag time segment and non-lag time segment, with criterions and related parameters provided as well. The term apparent elastic modulus is defined. The test data analysis shows that there exist a linear relationship between the apparent modulus and instant vertical force before load damage in non-lag time segment. On the preceding basis, a rate-dependent model of triangular wave un-installation section in non-lag time segment is established. Due to the inability of the loading equipment to accurately input the triangle wave, the average loading rate is amended and a constant term is added into it. The model is proved to be reliable, as the predicted value of the deformation rate and the stress strain curve coincides with measured value. At the same time, the impact of the lag time is pointed out quantitatively and a predication model of lag time segment is set up.


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