Vasculitis leucocitoclástica asociada a medicamentos

2019 ◽  
Vol 1 (1) ◽  
pp. 110-114
Author(s):  
Angélica María Hernández Fernández ◽  
José Antonio Flores Vargas
Keyword(s):  
Female Patient ◽  
Leukocytoclastic Vasculitis ◽  
Thrombocytopenic Purpura ◽  
Case Presentation ◽  
Small Vessels ◽  
Nuclear Dust

Introduction. Leukocytoclastic vasculitis (LV) is the presence of leukocytoclasis (fragmentation of the nuclei of neutrophils or "nuclear dust") in the wall of small vessels and around them. Case Presentation. A 37-yearold female patient with a diagnosis of thrombocytopenic purpura who starts treatment with ceftazidime and phenytoin, which causes LV. Conclusions. The case presented is associated with pharmacological etiology because the patient does not present a concomitant etiological condition.

A Case Report on the Surgical Management of Subhepatic Perforated Appendicitis: A Rare Presentation

2020 ◽  
Author(s):  
Mumin Hakim ◽  
Rania Mostafa ◽  
Mohammed Al Shehri ◽  
Sherif Sharawy
Keyword(s):  
Case Report ◽  
Acute Appendicitis ◽  
Female Patient ◽  
Surgical Management ◽  
Perforated Appendicitis ◽  
Exploratory Laparotomy ◽  
Atypical Presentation ◽  
Review Of Literature ◽  
Rare Presentation ◽  
Case Presentation

Abstract Background: Subhepatic appendicitis is an exceedingly rare presentation accounting for 0.01% of Acute appendicitis. It is of prime importance to be aware of various variants and thereby managing such challenging cases accordingly.Case presentation: We present a middle-aged female patient with subhepatic perforated appendicitis and peritonitis who underwent an exploratory laparotomy and appendectomy.Conclusions: Surgical management of such patients is challenging due to an atypical presentation. The surgical management of such patients is discussed with a brief review of literature.

scholarly journals Becker’s nevus syndrome: a case report 

2021 ◽  
Vol 15 (1) ◽  
Author(s):  
Ugo N. Chikani ◽  
Ijeoma N. Ohuche ◽  
Ada I. Bisi-Onyemaechi
Keyword(s):  
Case Report ◽  
Female Patient ◽  
Pediatric Endocrinology ◽  
Ipsilateral Breast ◽  
Epidermal Nevus ◽  
Case Presentation ◽  
Breast Hypoplasia ◽  
Becker’S Nevus ◽  
Nigeria Teaching Hospital ◽  
Endocrinology Clinic

Abstract Background Becker’s nevus syndrome is a syndrome characterized by the presence of a Becker’s nevus with ipsilateral breast hypoplasia or hypoplastic defects of the muscle, skin, or skeleton. The nevus usually consists of a circumscribed, unilateral, irregularly shaped hyperpigmented macule, commonly occurring around the anterior upper trunk, with/without hypertrichosis and/or acneiform lesions. This rare syndrome has not been reported in our locality to the best of our knowledge. Case presentation We report the case of a 15-year-old Igbo female patient who presented to our pediatric endocrinology clinic, University of Nigeria Teaching Hospital, Enugu, with complaints of asymmetry of the breasts and hyperpigmented macules on the side. Based on her symptoms, diagnosis of Becker’s nevus syndrome was made. The diagnosis of Becker’s nevus syndrome is mostly clinical, based on the presence of a Becker’s nevus with ipsilateral breast hypoplasia or hypoplastic defects of the muscle, skin, or skeleton. In our patient, there was a Becker’s nevus with ipsilateral breast hypoplasia. This syndrome, belonging to the class of epidermal nevus syndromes, is very rare, and is usually benign. She was placed on spironolactone tablets 50 mg daily, which have been associated with an improvement in the size of the hypoplastic breast, and her fears were allayed. Conclusion This syndrome has not been reported in our locality to the best of our knowledge and, therefore, has a propensity for misdiagnosis by clinicians because of its rarity. We therefore report this to create awareness among clinicians regarding this condition that is associated with much psychosocial trauma among patients, and that can be easily managed with oral spironolactone.

scholarly journals An extremely rare phenomenon: Angina bullosa hemorrhagica

2020 ◽  
pp. 102490792096481
Author(s):  
Mehmet Cihat Demir ◽  
İlter Ağaçkıran
Keyword(s):  
Emergency Department ◽  
Airway Obstruction ◽  
Female Patient ◽  
Soft Palate ◽  
Emergency Physician ◽  
Upper Airway ◽  
Case Presentation ◽  
Life Threatening ◽  
Hemorrhagic Bullae ◽  
Posterior Pharynx

Introduction: Angina bullosa hemorrhagica is a disease without a concomitant hematological or vesiculobullous disorder characterized by painless hemorrhagic bullae in the oral mucosa; it is rarely seen and has a good course. Case presentation: A 45-year-old female patient was admitted to the emergency department with a painless hemorrhagic bulla that suddenly appeared on the soft palate. A blister, 2 cm in diameter and dark red in color, was seen extending from the hard palate’s posterior to the soft palate. Nasolaryngoscopic evaluation was performed, and no additional hemorrhagic bulla was detected. She was discharged with the recommendation of oral mouthwash. Discussion: Solitary hemorrhagic bulla, suddenly occurring on the soft palate, is diagnostic for angina bullosa hemorrhagica. Some authors have reported that blisters in the posterior pharynx may progress to acute upper airway obstruction. Conclusion: Early nasolaryngoscopic evaluation in angina bullosa hemorrhagica is an excellent option to be considered by the emergency physician to prevent life-threatening situations.

scholarly journals Disseminated Nocardia infection in a female patient with idiopathic thrombocytopenic purpura and long-term glucocorticoid use

2018 ◽  
Vol 27 (1) ◽  
pp. 51-55 ◽  
Author(s):  
Shu Li ◽  
Qingbian Ma ◽  
Shuo Li ◽  
Yaan Zheng ◽  
Yujiao Chen ◽  
...  
Keyword(s):  
Female Patient ◽  
Idiopathic Thrombocytopenic Purpura ◽  
Opportunistic Infections ◽  
Combined Therapy ◽  
Delayed Diagnosis ◽  
Clinical Manifestations ◽  
The Body ◽  
Thrombocytopenic Purpura ◽  
Insidious Onset

Introduction: Nocardiosis is a rare kind of opportunistic infections. Because of its insidious onset and atypical clinical manifestations, diagnosis and early treatment are often delayed. Case presentation: Here we present a 60-year-old Chinese female patient with systemic Nocardia infection, who had been diagnosed with idiopathic thrombocytopenic purpura previously and was misdiagnosed for up to 6 months prior to presenting at our hospital and ultimately achieved clinical cure. Discussion: The patient took prednisone because of ITP for several years which led to immunosuppression. Nocardia infection began from the skin rupture and then spread all over the body with multiple system involvement. The pus culture eventually found Nocardia. Sulphonamides have been the standard treatment for decades and there are several other options. Patients with severe Nocardia infection or immunosuppression are suggested a combined therapy. Conclusion: Nocardiosis is an infection that often resulted in delayed diagnosis because of lack of specificity of the clinical profile and the difficulty in culturing the bacteria. It should be included in the differential diagnosis of patients in which there are cutaneous, respiratory or neurological manifestations, especially in immunosuppressed individuals.

scholarly journals The Role of Trichoscopy in Keratosis Follicularis Spinulosa Decalvans: Case Report and Review of the Literature

2020 ◽  
pp. 1-7
Author(s):  
Aurora Alessandrini ◽  
Giancarlo Brattoli ◽  
Bianca Maria Piraccini ◽  
Ambra Di Altobrando ◽  
Michela Starace
Keyword(s):  
Case Report ◽  
Female Patient ◽  
Clinical Features ◽  
Diagnosis And Treatment ◽  
Skin Involvement ◽  
Review Of The Literature ◽  
Case Presentation ◽  
Keratosis Follicularis ◽  
Scarring Alopecia

<b><i>Introduction:</i></b> Keratosis follicularis spinulosa decalvans (KFSD) is a rare, X-linked, hereditary disorder of keratinization, characterized by skin involvement and progressive scarring alopecia of scalp, eyebrows, and eyelashes. The diagnosis is helped by the particular clinical features, but pathology is mandatory. <b><i>Case Presentation:</i></b> We described a case of a female patient referred to the outpatient’s hair consultation of our department, in which we performed trichoscopy as a very useful tool for the diagnosis, followed by pathology that confirmed KFSD. <b><i>Conclusion:</i></b> In our article, we underlined the importance of trichoscopy for the diagnosis of this hair disease, with also a review of the literature on diagnosis and treatment.

Leukocytoclastic Vasculitis Following COVID-19 Vaccination: A Case Report

2021 ◽  
pp. 001857872110673
Author(s):  
Juny Sebastian ◽  
Merrin Mathew ◽  
Veeranna Sharsty ◽  
Madhan Ramesh
Keyword(s):  
Causality Assessment ◽  
Leukocytoclastic Vasculitis ◽  
Lower Limbs ◽  
Temporal Association ◽  
Causal Association ◽  
Laboratory Findings ◽  
Case Presentation ◽  
The Past ◽  
History Of ◽  
Day By Day

Background: Hypersensitivity or Leukocytoclastic vasculitis (LCV) following the COVID-19 vaccination has been reported rarely all over the world. LCV can be induced by certain factors such as infections, autoimmune disorders, malignancy, or some classes of drugs. Case presentation: A 32-year-old man, who was a known case of seizure disorder from his childhood presented to the department of dermatology with itchy red lesions on extremities and abdomen for the past 1 month. He explains a history of COVID-19 vaccination 1-month back and experienced itching on his lower limbs on the same day at night. A gradual worsening of the condition was observed day by day. He was hospitalized and diagnosed as LCV through clinical and laboratory findings. Conclusion: This case highlights a temporal association with the event of vaccination. The causality assessment showed an indeterminate causal association to LCV with COVID-19 Vaccination.

scholarly journals Splenic Primary Follicular Lymphoma With Idiopathic Thrombocytopenic Purpura: Report of a Case

2018 ◽  
Vol 103 (7-8) ◽  
pp. 366-370
Author(s):  
Ryoga Hamura ◽  
Hiroaki Shiba ◽  
Yoshihiro Shirai ◽  
Kenei Furukawa ◽  
Takashi Horiuchi ◽  
...  
Keyword(s):  
Follicular Lymphoma ◽  
Idiopathic Thrombocytopenic Purpura ◽  
Fluorescent In Situ Hybridization ◽  
Rare Condition ◽  
Oral Prednisolone ◽  
High Dose ◽  
Histologic Diagnosis ◽  
Thrombocytopenic Purpura ◽  
Case Presentation

Introduction: Primary splenic lymphoma is a rare condition that accounts for approximately 1% of non-Hodgkin's lymphoma. No primary splenic follicular lymphoma with idiopathic thrombocytopenic purpura (ITP) has been reported in the literature. Case presentation: A 41-year-old man was diagnosed with idiopathic thrombocytopenic purpura (ITP), and received steroid maintenance treatment with oral prednisolone 13 mg/d for 6 years. However, the platelet counts were 20 × 103 /μL or less. Abdominal enhanced computer tomography (CT) revealed splenomegaly. He underwent laparoscopic splenectomy after preoperative high-dose immunoglobulin preparation (30 mg/d intravenously for 5 days) which were effective in the improvement of platelets count (130 × 103 /μL). The histologic diagnosis was B cell type follicular lymphoma of the spleen. Fluorescent in situ hybridization (FISH) revealed a t(14; 18)(q32; q21) translocation, which supported the diagnosis of primary follicular lymphoma of the spleen. After the operation, the patient showed satisfactory recovery, and was discharged on postoperative day 7. He remains well with the platelet count of more than 200 × 103 / μl without medication. We herein report such a case. Conclusion: To the best of our knowledge, this is the first reported case of splenic primary follicular lymphoma with ITP.

scholarly journals Anterior orbital leiomyoma originating from the supraorbital neurovascular bundle

2017 ◽  
Vol 5 ◽  
pp. 2050313X1774099
Author(s):  
Selam Yekta Sendul ◽  
Cemile Ucgul Atilgan ◽  
Fevziye Kabukcuoglu ◽  
Semra Tiryaki Demir ◽  
Dilek Guven
Keyword(s):  
Differential Diagnosis ◽  
Dermoid Cyst ◽  
Female Patient ◽  
Excisional Biopsy ◽  
Young Female ◽  
Neurovascular Bundle ◽  
Upper Eyelid ◽  
Case Presentation ◽  
Orbital Tumour

Purpose: To present a young female patient with left anterior orbital leiomyoma that originates from the supraorbital neurovascular bundle. Case presentation: A 41-year-old female patient was admitted to our clinic with a complaint of swelling of the left upper eyelid. Based on the ophthalmological and imaging assessments, the excisional biopsy with the preliminary diagnosis of dermoid cyst was planned. The histopathological and immunohistochemical examinations of excised sample revealed surprisingly that the tumour was a leiomyoma. No recurrence was detected in the patient’s follow-up. Conclusion: Although it is rare, orbital leiomyoma should be considered in the differential diagnosis of patients with orbital tumour.

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