scholarly journals Conjunctivitis and other ocular manifestation following COVID-19; updated information about transmission of COVID-19 by eye

2021 ◽  
Vol 7 (2) ◽  
pp. e28-e28
Author(s):  
Mohsen Mirshamsi ◽  
Nasrin Ghiasi ◽  
Sharareh Heidari ◽  
Parisa Hosseinpour ◽  
Babak Hassanlouei ◽  
...  
Keyword(s):  
Foreign Body ◽  
Dry Eye ◽  
Health Problem ◽  
Contact Lenses ◽  
Ocular Symptom ◽  
Current Evidence ◽  
Ocular Involvement ◽  
Ocular Manifestation ◽  
Conjunctival Hyperemia ◽  
Body Sensation

Coronavirus disease 2019 (COVID-19) was reported in Wuhan, in late December 2019 and was became a pandemic health problem worldwide. In this review, the current evidence related to the ocular transmission of SARS-CoV-2 and its common manifestations was studied. According to this review, 7% to 69.4% of patients had at least an ocular symptom following COVID-19. Ocular symptom are bilateral or unilateral conjunctivitis, increased secretion, eye itching and foreign body sensation, epiphora, dry eye, conjunctival congestion, eye pink, conjunctival hyperemia, and chemosis. SARS-CoV-2 particles were found in tears and conjunctiva. Therefore, the transmission of COVID-19 by conjunctiva is possible. Then, it is essential to wear eye shield to protect against developing ocular involvement by COVID-19 because personal glasses and contact lenses cannot protect from COVID-19.

To evaluate the clinical efficacy of Palash Mula Arka in Pittaja Netrabhishyanda.

2016 ◽  
Vol 2 (1) ◽  
Author(s):  
Yuwaraj D. Kale ◽  
Sarika Choure
Keyword(s):  
Foreign Body ◽  
Modern Science ◽  
Signs And Symptoms ◽  
Burning Sensation ◽  
Trial Group ◽  
Inflammatory Condition ◽  
Conjunctival Hyperemia ◽  
Bacterial Conjunctivitis ◽  
Body Sensation ◽  
Acute Bacterial Conjunctivitis

Abhishyanda is one of the Sarvagata Vyadhi mentioned by Acharya Sushruta. In modern science, signs and symptoms of Netrabhishyanda may be correlated with conjunctivitis, which is the inflammatory condition of conjunctiva. Kavala Dharana, Dhumrapana, Aschyotana, Sechana Putapaka etc. are various suggested regimens in Ayurvedic texts for the treatment of Netrabhishyanda. Considering this effectiveness of Palasha as mentioned by Acharya Sushruta, it is planned to study the use of Palasha Mula Arka Aschyotana in Pittaja Netrabhishyanda. 60 patients having classical signs and symptoms of Pittaja Abhishyanda (Acute Bacterial Conjunctivitis) as per Ayurvedic and modern texts were selected for the study. After completion of therapy, mean Conjunctival hyperemia was reduced to 0.2167 ± 0.4086 in Control and 0.5667 ± 0.5040 in Trial Group. Palasha Mula Arka was found effective in reduction in conjunctival hyperemia, watering and the number of culture colonies, it was also found effective in burning sensation, discharge, foreign body sensation and photophobia.

scholarly journals Recurrent keratoconjunctivitis as the sole manifestation of COVID-19 infection: A case report

2021 ◽  
pp. 112067212110065
Author(s):  
Satria Audi Hutama ◽  
Firas Farisi Alkaff ◽  
Ryan Enast Intan ◽  
Citra Dewi Maharani ◽  
Luki Indriaswati ◽  
...  
Keyword(s):  
Case Report ◽  
Foreign Body ◽  
Foreign Body Sensation ◽  
Polymerase Chain Reaction Test ◽  
Nasopharyngeal Swab ◽  
Conjunctival Hyperemia ◽  
Blurred Vision ◽  
Ocular Symptoms ◽  
Body Sensation ◽  
Fluorescence Test

Introduction: Ocular symptoms are uncommon manifestations of coronavirus disease 2019 (COVID-19) infection. Earlier study reported that dry eye, blurred vision, foreign body sensation, tearing, itching, conjunctival secretion, conjunctival congestion, ocular pain, and photophobia are among the ocular symptoms that could be found in COVID-19 patients. However, there are only a few reports available regarding corneal involvement in this disease. Here we report a case of keratoconjunctivitis as the only symptom of COVID-19 infection. Case description: A 27-year-old man who worked as an obstetrics and gynecology resident came to the outpatient clinic with the chief complaints of eye discomfort, foreign body sensation, conjunctival hyperemia, lacrimation, and photophobia in his right eye for the past 3 weeks. Fluorescence test showed a small corneal lesion. The patient was then diagnosed with keratoconjunctivitis. A week after the treatment, all symptoms were resolved. A month later, the patient came to the emergency room with the same eye complaints but with a more severe pain. The fluorescence test showed wider corneal lesion compared to last month. The result from the corneal swab is negative for bacterial or fungal infection, indicating a viral infection. Afterwards, reverse transcriptase polymerase chain reaction test from nasopharyngeal swab was performed and revealed that the patient was positive for COVID-19. Conclusions: This case report showed that keratoconjunctivitis may occur as the only manifestation of COVID-19 infection. Thus, patient presented with unexplainable eye symptoms should be evaluated for COVID-19 infection.

scholarly journals Frequently Experienced Problems in the Early Stages after Prescribing Rigid Gas Permeable Contact Lenses

2021 ◽  
Vol 20 (4) ◽  
pp. 135-139
Author(s):  
Dong Ho Lee
Keyword(s):  
Visual Acuity ◽  
Foreign Body ◽  
Contact Lenses ◽  
Foreign Body Sensation ◽  
Corneal Curvature ◽  
Slit Lamp ◽  
Body Sensation ◽  
Quality Of Vision ◽  
Slit Lamp Microscopy

Prescribing rigid gas-permeable (RGP) lenses involves a series of processes that determine the most appropriate final lens through the trial use of test lenses based on the results of slit lamp microscopy, measuring refraction and corneal curvature, and corneal topography. The final prescription is reached by judging the dynamic lens movement, adequacy of the tear layer around the lens, corrected vision, and quality of vision. Various problems are encountered soon after prescribing lenses, including foreign body sensation, tear hypersecretion, decreased visual acuity, blurring, visual acuity change, redness, dryness, sudden pain, lens centering, and lens fallout. Here, we examine these problems and how to solve them.

scholarly journals Two Patients with Dry Eye Disease Followed Up Using an Expression Assay of Ocular Surface Mucin

2016 ◽  
Vol 7 (1) ◽  
pp. 208-215 ◽  
Author(s):  
Yumiko Machida ◽  
Jun Shoji ◽  
Natsuko Harada ◽  
Noriko Inada
Keyword(s):  
Foreign Body ◽  
Dry Eye ◽  
Ocular Surface ◽  
Combined Treatment ◽  
Eye Disease ◽  
Subjective Symptoms ◽  
Once Daily ◽  
Expression Levels ◽  
Body Sensation ◽  
Ophthalmic Suspension

Purpose: We report 2 patients with dry eye disease followed up using the expression levels of ocular surface mucin. Case Reports: Patient 1: a 57-year-old woman with Sjögren's syndrome-associated dry eyes experienced severe dryness and foreign body sensation in both her eyes, and instilled sodium hyaluronate ophthalmic solution 0.3% about 10-15 times daily. We measured the expression levels of MUC5AC mRNA (MUC5AC) and MUC16 mRNA (MUC16) by using real-time reversed transcription polymerase chain reaction for the specimens of modified impression cytology. Expression levels of MUC5AC and MUC16 on her ocular surface were very low. Subjective symptoms and expression levels of ocular surface mucin improved after combined treatment of rebamipide (4 times daily) and fluorometholone (once daily) ophthalmic suspension. Patient 2: a 62-year-old man with chronic graft-versus-host disease-associated dry eye experienced severe foreign body sensation and developed superficial punctate keratopathy with mucous thread and filamentary keratitis. Expression level of MUC5AC was very high at baseline. Subjective symptoms and expression levels of ocular surface mucin improved by combined treatment of rebamipide (4 times daily) and fluorometholone (once daily) ophthalmic suspension. Conclusion: Clinical test for MUC gene expression on the ocular surface was found to be useful in the follow-up of dry eye treatment.

scholarly journals Effects of Oral Vitamin B1 and Mecobalamin on Dry Eye Disease

2020 ◽  
Vol 2020 ◽  
pp. 1-9
Author(s):  
Xiaotong Ren ◽  
Yilin Chou ◽  
Xiaodan Jiang ◽  
Ran Hao ◽  
Yuexin Wang ◽  
...  
Keyword(s):  
Patient Satisfaction ◽  
Foreign Body ◽  
Dry Eye ◽  
Vitamin B1 ◽  
Foreign Body Sensation ◽  
Eye Drops ◽  
Artificial Tears ◽  
Oral Vitamin ◽  
Body Sensation ◽  
Group 3

Purpose. To assess the effects of oral vitamin B1 and mecobalamin on dry eye disease (DED) and patient satisfaction with treatment. Methods. In this randomized controlled study, DED patients were divided into 4 groups based on treatment: group 1, only artificial tears; group 2, corticosteroid eye drops and artificial tears; group 3, oral vitamin B1, mecobalamin, and artificial tears; and group 4, oral vitamin B1, mecobalamin, corticosteroid eye drops, and artificial tears. DED symptoms, signs, and patient satisfaction with treatment were assessed at baseline and at 1 and 2 months after treatment. Results. In total, 152 eyes from 76 patients (age, 55.25 ± 18.16 years) were included. In group 3, there were significant differences in dryness, foreign body sensation, burning, and tear film breakup time first (TBUTF) between 1 and 2 months after treatment and in satisfaction scores before and after treatment (P<0.05). In group 3, there were also significant differences in dryness, foreign body sensation, photophobia, and TBUTA and between baseline and 2 months after treatment (P<0.05). There was a significant difference in foreign body sensation between 1 and 2 months after treatment in groups 3 and 4 (P<0.05). Furthermore, we also find obvious improvement in corneal nerve fiber density (CNFD) between baseline and 1 and 2 months after treatment in groups 3 and 4 (P<0.05). Conclusions. Oral vitamin B1 and mecobalamin can relieve some dry eye symptoms such as dryness, pain, and photophobia and improve DED signs and patient satisfaction. Thus, vitamin B1 and mecobalamin are potential treatment options for patients with DED.

scholarly journals Ocular Manifestations in Psoriasis Screening (OcMaPS) Questionnaire: A Useful Tool to Reveal Misdiagnosed Ocular Involvement in Psoriasis

2021 ◽  
Vol 10 (5) ◽  
pp. 1031
Author(s):  
Angelo Ruggiero ◽  
Gabriella Fabbrocini ◽  
Sara Cacciapuoti ◽  
Eleonora Cinelli ◽  
Lucia Gallo ◽  
...  
Keyword(s):  
Dry Eye ◽  
Inflammatory Disease ◽  
Chronic Inflammatory Disease ◽  
Ocular Involvement ◽  
Ophthalmological Examination ◽  
Ocular Manifestation ◽  
Ocular Manifestations ◽  
Ocular Symptoms ◽  
Immune Mediated ◽  
Ocular Disorders

Psoriasis is an immune-mediated, chronic inflammatory disease, which mainly affects the skin, although it has systemic pathological effects. Comorbidities of psoriasis include ocular disorders, which are often nonspecific or mildly symptomatic. The aim of this study was to show the importance of ocular-disease screening in psoriatic patients using the Ocular Manifestations in Psoriasis Screening (OcMaPS) questionnaire. Patients suffering from moderate-to-severe psoriasis referring at our outpatient-clinic were consecutively enrolled. Each patient was asked to complete a screening questionnaire (OcMaPS). Patients reporting ocular symptoms were referred for an ophthalmological examination. A total of 372 patients were enrolled in the study. Ocular symptoms were detected in 39 patients (10.5%), and 37 patients were referred to ophthalmological examination which confirmed the presence of ocular manifestation in 30 patients. There were three cases (10%) of uveitis, 14 (46.6%) of dry eye and 13 (43.3%) of cataract, in progress or already treated with surgery. In the remaining seven patients, no ocular manifestations were found. Ocular manifestations in psoriatic patients are not rare. It is important to be aware of ocular symptoms in psoriatic patients, screening patients (with a consultation or OcMaPS questionnaire), which leads to earlier diagnosis and treatment.

scholarly journals Characterization of Meibomian Gland Dysfunction in Patients with Rosacea

2020 ◽  
Author(s):  
Eduardo Buzolin Barbosa ◽  
Carla Melo Tavares ◽  
Dimitri Felipe Luz da Silva ◽  
Lorraine Souza Santos ◽  
Andrea Fernandes Eloy da Costa França ◽  
...  
Keyword(s):  
Dry Eye ◽  
Ocular Surface ◽  
Tear Film ◽  
Meibomian Gland ◽  
Rupture Time ◽  
Meibomian Gland Dysfunction ◽  
Ocular Involvement ◽  
Conjunctival Hyperemia ◽  
Film Rupture ◽  
Glandular Secretion

Abstract Background: Rosacea frequently evolve the eyes with impact on life and vision quality. There are gaps in the understanding of ocular involvement, specially related to eyelid glands, which share common features to sebaceous glands.Purpose: Describe ocular surface disease related to Rosacea and its associations.Methods: Ninety-three individuals were selected to this cross-sectional, observational, non-interventionist study, divided into groups: rosacea (n=40) and controls (n=53). We investigated objective parameters of the ocular surface (conjunctival hyperemia, tear film stability and volume, meibomian gland dysfunction, dry eye disease, ocular surface staining) comparing healthy individuals with rosacea patients.Results: 69.23% of rosacea group were women, mean age of 47.34 ± 12.62 years old. Compared to matched controls there was no statistically significant differences regarding to visual acuity (p=0.987) and tear film parameters (tear meniscus height (p=0.338), non-invasive tear film rupture time (NIBUT) (p= 0.228), invasive rupture time (TBUT) (p=0.471) and Schirmer's test (p=0.244)) as well as conjunctival hyperemia (p = 0.106), and fluorescein staining (p = 0.489). Significant association was found in meibography evaluation (p = 0.026), mucous layer integrity (p = 0.015) and ocular surface symptoms (p <0.0001). Rosacea patients also showed important eyelid changes: glandular expressibility (p <0.001), glandular secretion pattern (p <0.001) and telangiectasia (p <0.001) compared to controls.Conclusion: Meibomian gland dysfunction is frequently associated to dermatologic conditions and is characterized by morphological findings in the meibography as well as lipid secretion impairment that lead to evaporative dry eye and ocular surface dysfunction and inflammation.

scholarly journals Applications of Hyaluronic Acid in Ophthalmology and Contact Lenses

Molecules ◽  
2021 ◽  
Vol 26 (9) ◽  
pp. 2485
Author(s):  
Wan-Hsin Chang ◽  
Pei-Yi Liu ◽  
Min-Hsuan Lin ◽  
Chien-Ju Lu ◽  
Hsuan-Yi Chou ◽  
...  
Keyword(s):  
Hyaluronic Acid ◽  
Dry Eye ◽  
Water Retention ◽  
Contact Lenses ◽  
Anterior Segment ◽  
Vitreous Body ◽  
Material Surface ◽  
Connective Tissues ◽  
Water Retention Properties ◽  
Bull's Eye

Hyaluronic acid (HA) is a glycosaminoglycan that was first isolated and identified from the vitreous body of a bull’s eye. HA is ubiquitous in the soft connective tissues of animals and therefore has high tissue compatibility for use in medication. Because of HA’s biological safety and water retention properties, it has many ophthalmology-related applications, such as in intravitreal injection, dry eye treatment, and contact lenses. Due to its broad range of applications, the identification and quantification of HA is a critical topic. This review article discusses current methods for analyzing HA. Contact lenses have become a widely used medical device, with HA commonly used as an additive to their production material, surface coating, and multipurpose solution. HA molecules on contact lenses retain moisture and increase the wearer’s comfort. HA absorbed by contact lenses can also gradually release to the anterior segment of the eyes to treat dry eye. This review discusses applications of HA in ophthalmology.

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