scholarly journals Comparitive Evaluation of Novel Desensitising Agents on Dentinal Tubule Occlusion-A Scanning Electron Microscopic Study

Author(s):  
Dr. Madhavi Ajit Shetty ◽  
Dr. Sharad Kokate ◽  
Dr. Vibha Hegde

Aim: To comparatively evaluate the occlusion of dentinal tubules by four novel desensitizing agents for treatment of Dentinal Hypersensitivity. Materials and Methods: The Diode Laser and three commercially available Desensitizers the NovaminR group- (SHY-NMTM), Colgate Sensitive Pro-relief, Gluma were investigated in this study. 30 extracted mandibular molars were used (n=30). They were divided into 5 groups including the control group in which no treatment was done. Teeth were ground under water-cooled trimming wheel, to prepare flat dentin surfaces. The dentin surfaces were etched to remove any smear plugs and to mimic the open dentinal tubules of sensitive dentin using 0.5 M Ethylene Diamine Tetraacetic Acid (pH 7.4) for two minutes (applied with a micro brush) and then rinsed with an air-water syringe for 30 seconds.

1981 ◽  
Vol 45 (03) ◽  
pp. 276-281 ◽  
Author(s):  
S Ishimaru ◽  
E Berglin ◽  
H-A Hansson ◽  
A-C Teger-Nilsson ◽  
G William-Olsson

SummaryA segment of the inferior vena cava was replaced by an expanded polytetrafluoroethylene graft in 13 dogs. Five of them served as a control group, while the other 8 were moderately or severely defibrinogenated with subcutaneous batroxobin. Plasma fibrinogen decreased to extremely low values throughout the experiment in the defibrinogenated dogs except in the moderately treated group in which it temporarily rose to 0.72-0.87 g/1 on the first postoperative day.Scanning electron microscopic observations of the haemostatic clot formed at the anastomoses of the graft revealed no significant morphological differences in platelet adhesion and/or aggregation between the three groups. These findings confirmed that platelets play a key role in primary haemostasis during defibrinogenation.The fibrin network was slightly diminished and only short fibrin filaments could be seen in the moderately and severely defibrinogenated groups respectively. These differences in composition of the clots are discussed in relation to their haemostatic capacity.


Author(s):  
Shaheen C ◽  
Preadeep Shukla ◽  
Gaurav Malhotra ◽  
Prerna Kataria ◽  
Mona Dagar

Background: the present study aims to evaluate whether fluoro calcium phospho silicate (Biomin or Elzenes) or in combination with Diode laser has better dentinal tubule occlusion and can be suggested as a effective treatment modality for patients with dentinal hypersensitivity. The objectives of the study were -to evaluate effectiveness of Fluoro calcium phospho silicate on dentinal tubules occlusion, to evaluate effectiveness of Fluoro calcium phospho silicate and laser and to compare its effect with Fluoro calcium phosphosilicate alone and laser on dentinal tubule occlusion, and to evaluate the effectiveness of laser on dentinal tubule occlusion. In study setting, SEM analysis was done at Sophisticated test and instrumentation centre, Cochin University of Science and Technology (CUSAT), Kerala. 120 Dentine specimens were obtained from sound premolars extracted for orthodontic purpose from the patients of age group 13 to 40 years. All the teeth were stored in 0. 2% thymol at room temperature. In our study, Fluoro calcium phospho silicate (Biomin) showed an average results of 70.37% completely occluded tubules and 23.48% of partially occluded tubules compared to 2.68% and 28.43% in the control group. Conclusion: In our invitro study the treated groups the specimens brushed with combination group (Biomin and Laser) showed the highest percentage of tubule occlusion followed by Biomin alone and then Laser. Hence from the results, it can be stated that combination of Biomin and laser can be considered as the best effective method in office treatment modality for dentinal hypersensitivity because of its ability to occlude more tubules.. Keywords: Diode laser, Biomin or Elzenes


2020 ◽  
Vol 10 (18) ◽  
pp. 6513
Author(s):  
Emilia Bologa ◽  
Simona Stoleriu ◽  
Gianina Iovan ◽  
Cristina Angela Ghiorghe ◽  
Irina Nica ◽  
...  

This in vitro study evaluated the effects of dentifrices containing nano-hydroxyapatite (n-HAp) on dentinal tubule occlusion and on mineral deposition. Dentin specimens of ten human teeth were submersed for 30 s in 40% citric acid and then randomly divided into four groups (three study groups and one control group). In the study groups, the dentin samples were exposed to three different n-HAp toothpastes: Karex (Dr. Kurt Wolff GmbH & Co. KG, Bielefeld, Germany), Biorepair Plus Sensitive (Coswell SpA, Bologna, Italy), and Dr. Wolff’s Biorepair (Dr. Kurt Wolff GmbH & Co. KG, Bielefeld, Germany); in the control group no toothpaste was applied. All of the samples were evaluated using scanning electron microscopy (SEM) and energy-dispersive X-ray (EDX) analysis. In the control group all of the samples showed a frank and wide opening of the dentinal tubules, whereas in the study groups different degrees of tubule closure by mineral depositions were observed. Toothpastes containing n-HAp determined a significant occlusion of dentinal tubules and a significant increase of mineral deposition on the dentin surface. All three tested toothpastes showed similar results regarding the degree of dentinal tubule closure. Varying degrees of differences in calcium, phosphate, carbon, and oxygen ion concentrations among the three tested toothpastes were obtained.


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