EFFECT OF COMPLEX PERIODONTAL TREATMENT IN PATIENTS WITH RHEUMATOID ARTHRITIS

2019 ◽  
Vol 33 (3) ◽  
pp. 23-28
Author(s):  
О. А. Глазунов ◽  
◽  
Д. В. Фесенко ◽  
С. А. Шнайдер ◽  
◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Periodontal Treatment

scholarly journals Effects of Conventional Synthetic Disease-Modifying Antirheumatic Drugs on Response to Periodontal Treatment in Patients with Rheumatoid Arthritis

2018 ◽  
Vol 2018 ◽  
pp. 1-7 ◽  
Author(s):  
Gyu-Un Jung ◽  
Ji-Young Han ◽  
Kyung-Gyun Hwang ◽  
Chang-Joo Park ◽  
Panagiota G. Stathopoulou ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Inflammatory Diseases ◽  
Periodontal Treatment ◽  
Control Group ◽  
Scaling And Root Planing ◽  
Disease Modifying Antirheumatic Drugs ◽  
Antirheumatic Drugs ◽  
Root Planing ◽  
Significant Difference ◽  
Disease Modifying

Rheumatoid arthritis (RA) and periodontitis are common chronic inflammatory diseases and periodontitis is known to be more common and more severe in patients with RA. Based on a paucity of studies about the relationship between common conventional synthetic disease-modifying antirheumatic drugs (csDMARDs) and periodontitis, this prospective study aimed to evaluate the adjunctive effect of csDMARDs on response to nonsurgical periodontal treatment in patients with RA. Thirty-two patients with RA (RA group) and 32 systemically healthy patients (control group) with periodontitis were included in this study. The RA group patients were treated with csDMARDs, such as methotrexate, hydroxychloroquine, and sulfasalazine. Conventional nonsurgical periodontal treatment with scaling and root planing was performed in both groups. The extent and severity of periodontitis were evaluated by plaque index (PI), gingival index (GI), probing depth (PD), clinical attachment level (CAL), and bleeding on probing (BOP) at baseline and 4 weeks after periodontal treatment. There was no statistically significant difference of periodontal parameters between the RA and control groups at baseline. Four weeks after scaling and root planing, PD reduction, and CAL gain were higher in the RA group treated with csDMARDs compared to the control group, and the difference was statistically significant (P = 0.006 and 0.003, respectively). A post hoc analysis of the RA group showed no statistically significant difference on the response to nonsurgical periodontal treatment in multiple csDMARDs therapy and addition of NSAIDs and/or steroids to csDMARDs. In patients with RA, csDMARDs showed beneficial effect on periodontal clinical parameters following the nonsurgical periodontal treatment.

scholarly journals Periodontal disease and influence of periodontal treatment on disease activity in patients with rheumatoid arthritis and spondyloarthritis

2019 ◽  
Vol 40 (3) ◽  
pp. 455-463 ◽  
Author(s):  
Katarzyna Białowąs ◽  
Małgorzata Radwan-Oczko ◽  
Irena Duś-Ilnicka ◽  
Lucyna Korman ◽  
Jerzy Świerkot
Keyword(s):  
Rheumatoid Arthritis ◽  
Periodontal Disease ◽  
Disease Activity ◽  
Early Stage ◽  
Periodontal Treatment ◽  
Number Of Teeth ◽  
Probing Depth ◽  
Significant Difference ◽  
Polymerase Chain ◽  
Oral Hygiene Instructions

Abstract The aim of this study was to assess the prevalence of periodontal disease and the effect of periodontal treatment in patients with rheumatoid arthritis (RA) and spondyloarthritis (SpA). Forty-four RA patients, thirty SpA patients and thirty-nine healthy volunteers were recruited to the study. Periodontal examination included the approximal plaque index (API), bleeding on probing (BoP), probing depth (PD) and number of teeth. Samples from the deepest periodontal pockets were taken for the detection of Porphyromonas gingivalis DNA with the use of the polymerase chain reaction. All subjects with periodontitis, who completed the study, received periodontal treatment consisting of scaling/root planing and oral hygiene instructions. Disease activity scores, clinical and laboratory parameters were assessed before and 4–6 weeks after periodontal treatment. No significant difference in the prevalence of periodontal disease and the presence of P. gingivalis DNA were found in RA and SpA patients compared to healthy controls. Significantly higher API (80% vs 63%; p = 0.01) and a lower number of teeth (20 vs 25, p = 0.001) were found in RA patients. BoP was significantly elevated in SpA patients (51% vs 33%, p = 0.02). Disease activity measured by the DAS28(CRP) was significantly reduced in RA patients after periodontal treatment (p = 0.002). Clinical and biochemical parameters were not improved in SpA patients. Nonsurgical periodontal treatment had an impact on the decrease in RA activity. Periodontal examination is necessary in patients with RA to detect and treat periodontitis at an early stage.

scholarly journals Influence of periodontal treatment on rheumatoid arthritis: a systematic review and meta-analysis

2017 ◽  
Vol 57 (3) ◽  
pp. 238-244 ◽  
Author(s):  
Débora Cerqueira Calderaro ◽  
Jôice Dias Corrêa ◽  
Gilda Aparecida Ferreira ◽  
Izabela Guimarães Barbosa ◽  
Carolina Castro Martins ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Systematic Review ◽  
Meta Analysis ◽  
Periodontal Treatment

Clinical and microbiological effects of non-surgical periodontal treatment in individuals with rheumatoid arthritis: a controlled clinical trial

Odontology ◽  
2020 ◽  
Author(s):  
Marcela F. Moura ◽  
Luís O. M. Cota ◽  
Tarcília A. Silva ◽  
Sheila C. Cortelli ◽  
Gilda A. Ferreira ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Clinical Trial ◽  
Periodontal Treatment ◽  
Controlled Clinical Trial

scholarly journals Relationship between periodontitis and rheumatoid arthritis and the effect of non-surgical periodontal treatment

2009 ◽  
Vol 20 (5) ◽  
pp. 355-364 ◽  
Author(s):  
Márcia de Noronha Pinho ◽  
Renê Donizeti Ribeiro Oliveira ◽  
Arthur Belém Novaes Jr. ◽  
Júlio César Voltarelli
Keyword(s):  
Rheumatoid Arthritis ◽  
Periodontal Treatment ◽  
Pocket Depth ◽  
Old Patients ◽  
Probing Pocket Depth ◽  
Sf 36 ◽  
Group 3 ◽  
The Relationship ◽  
Group 1

This study analyzed the association of periodontal disease (PD) and rheumatoid arthritis (RA). Seventy-five 35-60-year-old patients were assigned to 5 groups according to the presence (+) or not (-) of PD and RA and the treatment received (TR+) or not (TR-) for PD. Group 3 uses total prosthesis (TP). Clinical and laboratory evaluations were performed at baseline, 3 and 6 months of follow-up by probing pocket depth, bleeding on probing and plaque index for PD, HAQ, DAS28, SF-36 and laboratory: AAG, ESR, CRP for RA. Statistically significant differences for PD after 3 (p=0.0055) and after 6 months (p=0.0066) were obtained in Group 1 (RA+PD+TR+) and 2(RA+PD+TR-); significant reduction in the % of BOP after 6 months (p=0.0128) and significant reduction in the % of Pl after 3 (p=0.0128) and 6 months (p=0.0002) in Group 1. Statistically significant differences between Groups 1 and 3 (RA+TP) for DAS28 at baseline and after 3 months were observed, but not after 6 months. No other parameters for RA were significantly affected. The relationship between RA and PD disease activities is not clear, but the importance of periodontal treatment in the control of inflammation to avoid tooth extraction is evident.

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