Selection of light sources and radiation parameters in photodynamic therapy for skin diseases

2020 ◽  
Keyword(s):  
Photodynamic Therapy ◽  
Skin Diseases ◽  
Light Sources ◽  
Selection Of

Use of photodynamic therapy for photodamage skin (review of literature)

2019 ◽  
Vol 1 (7) ◽  
pp. 19-23
Author(s):  
S. I. Surkichin ◽  
N. V. Gryazeva ◽  
L. S. Kholupova ◽  
N. V. Bochkova
Keyword(s):  
Photodynamic Therapy ◽  
Comparative Evaluation ◽  
Clinical Manifestations ◽  
Light Sources ◽  
Review Of Literature ◽  
Photosensitizing Agents ◽  
Selection Of

The article provides an overview of the use of photodynamic therapy for photodamage of the skin. The causes, pathogenesis and clinical manifestations of skin photodamage are considered. The definition, principle of action of photodynamic therapy, including the sources of light used, the classification of photosensitizers and their main characteristics are given. Analyzed studies that show the effectiveness and comparative evaluation in the selection of various light sources and photosensitizing agents for photodynamic therapy in patients with clinical manifestations of photodamage.

Liquid-Crystalline Nanodispersions Containing Monoolein for Photodynamic Therapy of Skin Diseases: A Mini-Review

2017 ◽  
Vol 13 (5) ◽  
Author(s):  
Fabiola Garcia Praca ◽  
Raquel Petrilli ◽  
Josimar O. Eloy ◽  
Robert J. Lee ◽  
Maria Vitoria Lopes Badra Bentley
Keyword(s):  
Photodynamic Therapy ◽  
Liquid Crystalline ◽  
Skin Diseases

scholarly journals Photodynamic Therapy Combined with Antibiotics or Antifungals against Microorganisms That Cause Skin and Soft Tissue Infections: A Planktonic and Biofilm Approach to Overcome Resistances

2021 ◽  
Vol 14 (7) ◽  
pp. 603
Author(s):  
Vanesa Pérez-Laguna ◽  
Isabel García-Luque ◽  
Sofía Ballesta ◽  
Antonio Rezusta ◽  
Yolanda Gilaberte
Keyword(s):  
Photodynamic Therapy ◽  
Soft Tissues ◽  
Combined Treatment ◽  
Resistance Pattern ◽  
Antimicrobial Photodynamic Therapy ◽  
Antimicrobial Drugs ◽  
Bacteria And Fungi ◽  
High Level ◽  
Selection Of

The present review covers combination approaches of antimicrobial photodynamic therapy (aPDT) plus antibiotics or antifungals to attack bacteria and fungi in vitro (both planktonic and biofilm forms) focused on those microorganisms that cause infections in skin and soft tissues. The combination can prevent failure in the fight against these microorganisms: antimicrobial drugs can increase the susceptibility of microorganisms to aPDT and prevent the possibility of regrowth of those that were not inactivated during the irradiation; meanwhile, aPDT is effective regardless of the resistance pattern of the strain and their use does not contribute to the selection of antimicrobial resistance. Additive or synergistic antimicrobial effects in vitro are evaluated and the best combinations are presented. The use of combined treatment of aPDT with antimicrobials could help overcome the difficulty of fighting high level of resistance microorganisms and, as it is a multi-target approach, it could make the selection of resistant microorganisms more difficult.

Addressing pose estimation issues for machine vision based UAV autonomous serial refuelling

2007 ◽  
Vol 111 (1120) ◽  
pp. 389-396 ◽  
Author(s):  
G. Campa ◽  
M. R. Napolitano ◽  
M. Perhinschi ◽  
M. L. Fravolini ◽  
L. Pollini ◽  
...  
Keyword(s):  
Machine Vision ◽  
Pose Estimation ◽  
Estimation Algorithm ◽  
Computational Effort ◽  
Unmanned Aircraft ◽  
Light Sources ◽  
Estimation Algorithms ◽  
Trade Offs ◽  
Labeling Algorithms ◽  
Selection Of

Abstract This paper describes the results of an effort on the analysis of the performance of specific ‘pose estimation’ algorithms within a Machine Vision-based approach for the problem of aerial refuelling for unmanned aerial vehicles. The approach assumes the availability of a camera on the unmanned aircraft for acquiring images of the refuelling tanker; also, it assumes that a number of active or passive light sources – the ‘markers’ – are installed at specific known locations on the tanker. A sequence of machine vision algorithms on the on-board computer of the unmanned aircraft is tasked with the processing of the images of the tanker. Specifically, detection and labeling algorithms are used to detect and identify the markers and a ‘pose estimation’ algorithm is used to estimate the relative position and orientation between the two aircraft. Detailed closed-loop simulation studies have been performed to compare the performance of two ‘pose estimation’ algorithms within a simulation environment that was specifically developed for the study of aerial refuelling problems. Special emphasis is placed on the analysis of the required computational effort as well as on the accuracy and the error propagation characteristics of the two methods. The general trade offs involved in the selection of the pose estimation algorithm are discussed. Finally, simulation results are presented and analysed.

scholarly journals The Effect of Antimicrobial Photodynamic Therapy Using Chlorophyllin–Phycocyanin Mixture on Enterococcus faecalis: The Influence of Different Light Sources

2020 ◽  
Vol 10 (12) ◽  
pp. 4290 ◽  
Author(s):  
Nasim Chiniforush ◽  
Maryam Pourhajibagher ◽  
Steven Parker ◽  
Stefano Benedicenti ◽  
Abbas Bahador ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Diode Laser ◽  
Enterococcus Faecalis ◽  
Control Group ◽  
Human Gingival Fibroblast ◽  
Light Sources ◽  
Gingival Fibroblast ◽  
Antimicrobial Photodynamic Therapy ◽  
Cell Viability Assay ◽  
Vitro Effect

The purpose of this study was to evaluate the in vitro effect of the chlorophyllin–phycocyanin mixture (Photoactive+) as a photosensitizer (PS) during antimicrobial photodynamic therapy (aPDT) on the count of Enterococcus faecalis (E. faecalis) using different light sources. The antimicrobial effect of aPDT with chlorophyllin–phycocyanin mixture using different light sources including diode laser (λ = 660 nm), diode laser (λ = 635 nm), LED (λ = 450 ± 30 nm) alone or in combination was assessed using microbial cell viability assay against E. faecalis. In addition, the cell cytotoxicity of Photoactive+ was assessed on human gingival fibroblast (HuGu) cells by MTT assay; E. faecalis growth when treated by both red wavelengths (635 nm, 660 nm) and combination of LED (420–480 nm) and red wavelengths (635 nm, 660 nm), significantly reduced compared to the control group (p < 0.05). There was no significant reduction in the number of viable cells exposed to Photoactive+ compared to the control group (p < 0.05). This study shows that the application of chlorophyllin–phycocyanin mixture and irradiation with emission of red light achieved a better result for bacterial count reduction, compared to a control. This component can be applied safely due to very negligible cytotoxicity.

scholarly journals Selection of individual nutrition for patients with torpid course of atopic dermatitis

2020 ◽  
pp. 107-108
Author(s):  
Н.О. Артемьева ◽  
Е.В. Свечникова ◽  
Ю.В. Максимова ◽  
В.Н. Максимов
Keyword(s):  
Quality Of Life ◽  
Atopic Dermatitis ◽  
Inflammatory Disease ◽  
Skin Diseases ◽  
Disease Development ◽  
Physical Discomfort ◽  
Selection Of

Атопический дерматит (АД) - это воспалительное заболевание кожи, мультифакториальной или моногенный природы, характеризующееся зудом, хроническим рецидивирующим течением и возрастными особенностями локализации и морфологии очагов поражения. Доля заболевания в структуре кожных болезней в настоящее время составляет от 10 до 30%. Когда процесс приобретает упорное течение с невыраженным эффектом от проводимой терапии и обострениями процесса до 3-4 в год с увеличением их длительности, то становится вялотекущим (торпидным). Торпидное течение АД приводит больного к снижению качества жизни за счёт физического дискомфорта и эмоциональной дезадаптации. Подходы к лечению в теории зависят от механизма развития заболевания. Atopic dermatitis (AD) is an inherited inflammatory disease of skin, multifactor or monogenic nature, characterized by itching, chronic recurrent current and age-specific features of localisation and morphology of lesion centers. The proportion of the disease in the structure of skin diseases is currently between 10 and 30%. When the process acquires a persistent course with an unparalleled effect from the performed therapy and exacerbations of the process up to 3-4 per year with increase of their duration, it becomes sluggish (torpedo) [1, 3]. The torpedo course of AD leads the patient to a decrease in the quality of life due to physical discomfort and emotional disadaptation. Approaches to treatment in theory depend on the mechanism of disease development.

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