scholarly journals HISTOMORPHOMETRIC PARAMETERS IN SIMULATED GINGIVAL RECESSION

2020 ◽  
Vol 10 (4) ◽  
pp. 174-175
Author(s):  
Sania Yusupova ◽  
Ekaterina Kostrigina ◽  
Natalia Bulkina ◽  
Valery Konnov ◽  
Anna Vedyaeva ◽  
...  
Keyword(s):  
Connective Tissue ◽  
Morphological Changes ◽  
Gingival Recession ◽  
Sectional Area ◽  
Cross Sectional ◽  
Affected Area ◽  
Tissue Ischemia ◽  
Periodontal Tissues ◽  
Negative Effect ◽  
Periodontal Plastic Surgery

This study addresses the nature of morphological changes occurring in periodontal tissues through the development of gum recession in the experiment. Gingival recession was found to occur along with a decrease in epithelial thickness of the mucous membrane as well as a decreasing cross-sectional area of blood vessels, whereas the connective tissue featured fibrinoid swelling. Initial tissue ischemia in the affected area can have a negative effect on reparation. This should be borne in mind when planning a periodontal plastic surgery.

Estimating myofiber cross‐sectional area and connective tissue deposition with electrical impedance myography: a study in D2 ‐mdx mice

2021 ◽  
Author(s):  
Sarbesh R. Pandeya ◽  
Janice A. Nagy ◽  
Daniela Riveros ◽  
Carson Semple ◽  
Rebecca S. Taylor ◽  
...  
Keyword(s):  
Connective Tissue ◽  
Electrical Impedance ◽  
Cross Sectional Area ◽  
Mdx Mice ◽  
Sectional Area ◽  
Cross Sectional

scholarly journals Morphological changes during early trans-tibial prosthetic fitting

1998 ◽  
Vol 22 (2) ◽  
pp. 115-122 ◽  
Author(s):  
M. Lilja ◽  
P. Hoffmann ◽  
T. Öberg
Keyword(s):  
Morphological Changes ◽  
Muscle Group ◽  
Cross Sectional Area ◽  
Sectional Area ◽  
Cross Sectional ◽  
Transtibial Amputation ◽  
Negative Power ◽  
Lateral Muscle ◽  
Amputation Stump ◽  
The Cross

Morphological changes in the amputation stump may have serious implications regarding the suspension and fit of the prosthetic socket. In an earlier study (Lilja and Öberg, 1997) the authors have shown that the volume of the transtibial amputation stump decreases according to a negative power function after amputation, and that the stump volume does not stabilise until four months after the operation. In the present study, Magnetic Resonance Imaging (MRI) technique was used to examine morphological changes in the amputation stump after transtibial amputation in a small number of cases. The authors expected to find a decrease in the cross-sectional area of the stump and of the separate muscles similar to the findings in earlier studies. However, two different patterns were found. The cross-sectional area of the entire stump as well as that of the medial muscle group changed according to the authors' hypothesis, i.e. an initial fast decrease, followed by a more moderate decrease of the area. In the lateral muscle group another pattern was found. After an initial rapid decrease the area increased, sometimes to a magnitude larger than the initial value. After the amputation the lateral muscle group may acquire a new function, contributing to the suspension of the socket. Despite the limited number of patients, this study presents findings which may be important in the clinical fitting of trans-tibial prostheses.

Reduction in myotendinous junction surface area of rats subjected to 4-day spaceflight

1992 ◽  
Vol 73 (1) ◽  
pp. 59-64 ◽  
Author(s):  
J. G. Tidball ◽  
D. M. Quan
Keyword(s):  
Endoplasmic Reticulum ◽  
Connective Tissue ◽  
Surface Area ◽  
Rough Endoplasmic Reticulum ◽  
Myotendinous Junction ◽  
Relative Area ◽  
Sectional Area ◽  
Cross Sectional ◽  
Normal Loading ◽  
Folding Factor

The surface area of myotendinous junctions (MTJs), expressed relative to the cross-sectional area of myofibrils attached to them, was determined using established morphometric techniques in which the digitlike processes of the cell at MTJs are modeled as circular paraboloids. The relative area, called the folding factor, was measured for six rats after a 4-day spaceflight and six control rats maintained in a vivarium under otherwise identical conditions. Spaceflight resulted in a significant reduction in relative MTJ surface area, from 19.7 +/- 2.3 (SD) in control animals to 13.3 +/- 2.5 for animals after spaceflight. Furthermore, space animals displayed increased numbers of fibroblasts enriched in rough endoplasmic reticulum near the MTJ, a greater number of ribosomes and mitochondria within muscle at the MTJ, and increased occurrence of lesions in the connective tissue near the MTJ. The results indicate that spaceflight, possibly through the removal of gravity-associated loading from muscle, causes a modification in MTJ structure and may result in injuries at MTJs after return to normal loading.

The significance of morphological changes in cerebral arteries after subarachnoid hemorrhage

1990 ◽  
Vol 72 (4) ◽  
pp. 626-633 ◽  
Author(s):  
Marc R. Mayberg ◽  
Tomohisa Okada ◽  
Don H. Bark
Keyword(s):  
Subarachnoid Hemorrhage ◽  
Whole Blood ◽  
Vessel Wall ◽  
Structural Changes ◽  
Morphological Changes ◽  
Cerebral Arteries ◽  
Cross Sectional Area ◽  
Ultrastructural Changes ◽  
Sectional Area ◽  
Cross Sectional

✓ A porcine model was developed to allow quantitative assessment of morphological changes in cerebral arteries after subarachnoid hemorrhage and to determine the significance of structural changes in producing arterial narrowing. Whole blood was selectively applied to the middle cerebral artery (MCA) of seven pigs. After 10 days, vessels were perfusion-fixed and examined by light and transmission electron microscopy and immunohistochemistry. The MCA's exposed to whole blood for 10 days showed prominent luminal narrowing associated with profound ultrastructural changes affecting all layers of the vessel wall. Morphometric analysis, however, demonstrated that significant reductions in the luminal cross-sectional area (−55.8% ± 12.5%, p < 0.005) and increases in radial wall thickness (75.1% ± 10.5%, p < 0.005) were associated with only minimal increase in the cross-sectional area of the vessel wall (12.5% ± 15%,p < 0.025). By stereological analysis, the volume density of individual components of the arterial wall was unchanged in MCA's exposed to blood. Vessels exposed to blood showed a 44% reduction in smooth-muscle cell immunoreactive actin and increased collagen in the extracellular matrix of the vessel wall. These data suggest that structural changes in cerebral arteries after subarachnoid hemorrhage do not directly contribute to vessel narrowing through increases in wall mass. Nevertheless, such changes may reflect pathological mechanisms which act to augment prolonged vasoconstriction or inhibit the maintenance of normal vascular tone.

scholarly journals Clinical impact of platelet rich plasma in treatment of gingival recessions

2008 ◽  
Vol 136 (3-4) ◽  
pp. 95-103 ◽  
Author(s):  
Zoran Aleksic ◽  
Sasa Jankovic ◽  
Bozidar Dimitrijevic ◽  
Ana Pucar ◽  
Vojkan Lazic ◽  
...  
Keyword(s):  
Connective Tissue ◽  
Platelet Rich Plasma ◽  
Gingival Recession ◽  
Root Surface ◽  
Coronally Advanced Flap ◽  
Periodontal Tissues ◽  
Connective Tissue Graft ◽  
Tissue Graft ◽  
Keratinized Tissue ◽  
Prp Gel

Introduction Root coverage supported with complete regeneration of lost periodontal tissues represents the ultimate goal of gingival recession treatment. Objective This study was designed to evaluate clinical effectiveness of platelet rich plasma gel (PRP) with connective tissue graft (CTG) in the treatment of gingival recession. METHOD 15 gingival recessions Miller class I or II were treated with CTG and PRP (group PRP). Connective tissue graft was harvested from the premolar region using trap door technique. After elevation of the flap, the regional bone and root surface were smeared with activated PRP gel. CTG was also irrigated with PRP gel before placement over the exposed root surface and local bone. Fixed CTG was covered with a coronally advanced flap. The same number of gingival recessions were treated with CTG in combination with the coronally advanced flap with no PRP gel (group TVT). Clinical recordings included recession depth (RD), probing depth (PD), clinical attachment level (CAL) and keratinized tissue width (KT) before and 1 year after mucogingival surgical treatment. Results Mean value of RD was significantly decreased from 4.93?0.86 mm to 0.60?0.37 (p<0.01) with CTG and PRP and from 4.76?0.74 mm to 0.63?0.29 mm (p<0.01) in CTG group. This difference was not statistically significant. Results of the keratinized tissue width showed significant increase from 0.88? 0.30 mm presurgery to 3.78?0.49 mm (p<0.01) six months after treatment in PRP group and from 0.90?0.34 mm to 3.15?0.41 in TVT group (p<0.01). This difference was statistically significant (p>0.05). No statistically significant differences were observed between treatment groups in CAL and PD. Conclusion Clinical results validate both procedures as effective and highly predictable surgical techniques in solving gingival recession problem. Histological evaluation may confirm advantage of PRP use related to regeneration of periodontal tissues. .

scholarly journals Controlled Drought Affects Morphology and Anatomy of Salvia splendens

2005 ◽  
Vol 130 (5) ◽  
pp. 775-781 ◽  
Author(s):  
Stephanie E. Burnett ◽  
Svoboda V. Pennisi ◽  
Paul A. Thomas ◽  
Marc W. van Iersel
Keyword(s):  
Polyethylene Glycol ◽  
Morphological Changes ◽  
Stem Elongation ◽  
Cross Sectional Area ◽  
Vessel Element ◽  
Sectional Area ◽  
Cross Sectional ◽  
Salvia Splendens ◽  
Growing Medium ◽  
Peg 8000

Polyethylene glycol 8000 (PEG-8000) was applied to a soilless growing medium at the concentrations of 0, 15, 20, 30, 42, or 50 g·L-1 to impose controlled drought. Salvia (Salvia splendens F. Sellow. ex Roem & Shult.) seeds were planted in the growing medium to determine if controlled drought affects morphology and anatomy of salvia. Polyethylene glycol decreased emergence percentage and delayed emergence up to 5 days. Stem elongation of salvia treated with the five lowest concentrations was reduced up to 35% (21 days after seeding), and salvia were a maximum of 53% shorter and the canopy was 20% more narrow compared to nontreated seedlings 70 days after seeding. These morphological changes were attributed to PEG-8000 mediated reduction in leaf water potential (Ψw). The growing medium Ψw ranged from -0.29 to -0.85 MPa in PEG-8000 treated plants, and plant height was positively correlated with Ψw 21 days after seeding. Stem diameter of PEG-treated seedlings was reduced up to 0.4 mm mainly due to reductions in vascular cross-sectional area. Xylem cross-sectional area decreased more than stem and phloem cross-sectional area. Polyethylene glycol 8000 reduced vessel element number, but not diameter.

scholarly journals The Periodontium as a Potential Cause of Orofacial Pain: A Comprehensive Review

2018 ◽  
Vol 12 (1) ◽  
pp. 520-528
Author(s):  
Jaume Miranda-Rius ◽  
Lluís Brunet-Llobet ◽  
Eduard Lahor-Soler
Keyword(s):  
Orofacial Pain ◽  
Gingival Recession ◽  
Tissue Destruction ◽  
Periodontal Tissues ◽  
Pubmed Database ◽  
Wide Range ◽  
Gingival Enlargement ◽  
High Prevalence ◽  
Choice Of Treatment ◽  
Negative Effect

Introduction: Orofacial pain of periodontal origin has a wide range of causes, and its high prevalence and negative effect on patients' quality of life make intervention mandatory. This review provides a periodontological overview of the field of orofacial pain, focusing on the entities which involve the periodontal tissues and may be the cause of this pain or discomfort. Methods: The study comprised a literature search of these pathologies conducted in the MEDLINE/PubMed Database. Acute infectious entities such as gingival and periodontal abscesses are emergencies that require a rapid response. Periodontitis associated with endodontic processes, necrotizing periodontal disorders, desquamative gingivitis, gingival recession, and mucogingival herpetic lesions, cause mild to severe pain due to tissue destruction and loss. Other lesions that lead to periodontal discomfort include gingival enlargement and periodontal ligament strains associated with occlusal trauma, parafunctional habit and the impaction of food or foreign bodies. Conclusion: A range of therapeutic, pharmacological and surgical alternatives are available for the management of these injuries. However, the wide variety of causes of orofacial pain or periodontal discomfort may confuse the clinician during diagnosis and may lead to the wrong choice of treatment.

scholarly journals Clinical Comparison of the Subepithelial Connective Tissue versus Platelet-Rich Fibrin for the Multiple Gingival Recession Coverage on Anterior Teeth Using the Tunneling Technique

2017 ◽  
Vol 2017 ◽  
pp. 1-6
Author(s):  
Victor Fabrizio Cabrera Pazmiño ◽  
Miguel Agusto Riquelme Rodas ◽  
Carlos David Barrios Cáceres ◽  
Guillermo Gustavo Renault Duarte ◽  
Melanie Vanesa Cano Azuaga ◽  
...  
Keyword(s):  
Connective Tissue ◽  
Gingival Recession ◽  
Platelet Rich Fibrin ◽  
Periodontal Tissues ◽  
Connective Tissue Graft ◽  
Tissue Graft ◽  
Anterior Teeth ◽  
Clinical Comparison ◽  
Tunnel Technique ◽  
Subepithelial Connective Tissue Graft

The aim of this study was to evaluate and compare, clinically, the efficiency of the subepithelial connective tissue graft (SCTG) and platelet-rich fibrin (L-PRF) using the tunnel technique to cover the multiple gingival recessions on anterior teeth, in the same patient. Within the limits of this study, we conclude that both SCTG and L-PRF proved to be reliable options for the treatment of gingival recessions, efficiently supporting the biological and aesthetic demand, stimulating the periodontal tissues’ health, and bringing reliable and highly predictable results.

scholarly journals Correction with thiocetam of lead nanoparticles influence on morpho-functional status of rat liver

2020 ◽  
Vol 33 (3) ◽  
pp. 149-154
Author(s):  
Sergii Omelchuk ◽  
Vasyl Aleksiichuk ◽  
Yuri Chaikovsky ◽  
Liudmyla Sokurenko
Keyword(s):  
Body Weight ◽  
Morphological Changes ◽  
Liver Weight ◽  
Cross Sectional Area ◽  
Sectional Area ◽  
Cross Sectional ◽  
Relative Liver Weight ◽  
The Mean ◽  
Pharmacological Correction ◽  
The Cross

AbstractThe aim of this paper is to investigate the influence of Thiocetam on morphological changes in the liver of rats and on biochemical changes in their blood after exposure to lead nanoparticles and compounds. The liver is an organ that performs a number of functions, such as the synthesis of enzymes, hormones, plasma components and the neutralization of toxins. It is involved in many metabolic processes in the body.In undertaking this, colloidal solutions of lead sulphide nanoparticles at dosages 10 nm and 30 nm were injected into two groups of rats, PbSnano1 and PbSnano2, respectively, while group Pb(NO3) received subcutaneously a solution of lead nitrate in ion form in a dose of 1.5 mg/kg (0.94 mg/kg lead, in lead equivalent). After 60 administrations (12 weeks) of the studied substances, the exposure was discontinued and the animals were observed for 18 weeks. Subsequently, half of each group received Thiocetam by injection (for 6 weeks at a dose of 250 mg/kg) while the other half did not. We then assessed the mean body weight, absolute and relative liver weight, blood biochemistry values (total protein, albumin, glucose, total lipids, cholesterol, triglycerides levels in blood serum) and morphological changes in hepatocytes (morphological slides, nuclei cross-sectional area and cytoplasm cross-sectional area).The outcome of this work showed that the mean body weight of animals exposed to nanoparticles with Tiocetam did not differ from that of animals exposed to nanoparticles without pharmacological correction, but relative liver weight was statistically significantly higher than the corresponding values in rats without pharmacological correction. The morphological picture in all study group animals was characterized by the normalization of microvessel blood filling, structure of hepatic plates, disappearance of infiltration with lymphocytes and histiocytes. No dystrophic changes in hepatocytes were found. All this indicates the feasibility of preventive measures during exposure to lead nanoparticles, by administering Thiocetam.In both series of animals exposed to lead nanoparticles (PbSnano1 and PbSnano2), the cross-sectional area of the hepatocytes cytoplasm and the cross-sectional area of the hepatocytes nuclei were smaller than just after exposure, but in the series with Thiocetam adminstration, all the values did not differ from those in the control.

Morphological changes of macular soft drusen and drusenoid DPED after subthreshold micropulse laser treatment

2021 ◽  
Vol 2 (2) ◽  
pp. 95-100
Author(s):  
Qing-Shan Chen ◽  
◽  
Xia Zhao ◽  
Miao-Hong Chen ◽  
Yu-Hang Yang ◽  
...  
Keyword(s):  
Visual Acuity ◽  
Laser Treatment ◽  
Morphological Changes ◽  
Cross Sectional Area ◽  
Sectional Area ◽  
Cross Sectional ◽  
Micropulse Laser ◽  
Subthreshold Micropulse Laser ◽  
Soft Drusen ◽  
Baseline Values

AIM: To analyze the morphological changes of macular soft drusen and drusenoid pigmental epithelium detachment (DPED) after subthreshold micropulse laser treatment (SMLT). METHODS: Fourteen patients (20 affected eyes) with soft drusen and DPED clinically confirmed from August 2016 to October 2018, were included in this study. 577 nm yellow laser of SMLT was applied for soft drusen and DPED. The changes of soft drusen and DPED in best corrected visual acuity (BCVA)(LogMAR)and height, diameter and cross-sessional area according to fundus autofluorescence and SD-OCT examinations were observed after SMLT RESULTS: BCVA was not significant difference after treatment of soft drusen (P=0.260), and the DPED (P=0.736) than that of the baseline. Compared with the baseline values, the height and cross-sessional area of soft drusen were reduced at the 6mo after treatment, and the differences were statistically significant (P=0.008, P=0.034). Compared with the baseline values, the differences were not statistically significant in height, diameter and cross-sectional area of DPED after treatment. CONCLUSION: BCVA was not reduced for drusen and DPED after SMLT, however, the height and cross-sessional area of soft drusen was reduced compared with those before treatment, and the differences were not statistically significant in height, diameter and cross-sectional area of DPED before and after treatment. The results indicated that SMLT was effective for soft drusen, but was not effective for short-term treatment of DPED. SMLT caused no damage to the visual acuity in treatment of soft drusen and DPED, but prospective, controlled, large sample and long-term follow-up studies should be required.

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