scholarly journals INFILTRATIVE LUNG TUBERCULOSIS, PEPTIC ULCER DISEASE AND HIV INFECTION (COMORBIDITY AND MULTIMORBIDITY OF DISEASES)

2016 ◽  
Vol 1 (1) ◽  
pp. 19-24
Author(s):  
IL L Davydkin ◽  
AM M Osadchuk ◽  
EA A Borodulina ◽  
TA A Gritsenko

Aim - to explore the features of comorbidity and multimorbidity of infiltrative pulmonary tuberculosis (IPT), peptic ulcer (PU), HIV infection in modern conditions. Materials and methods. The study involved 392 patients with IPT aged 20-44 years, HIV-positive with CD4 200500/pl, suffering from uncomplicated ulcer. Results. Peptic ulcer disease was diagnosed in 20.5% of patients with IPT and 19.5% patients with HIV infection in stage C2 and IPT, complaining of dyspepsia. The multimorbid combination of IPT, HIV infection and PU is characterized by: oligosymptomatic onset of tuberculosis; the clinical picture shows the dominance of asthenic syndrome, manifestations of gastric and intestinal dyspepsia, weight loss (2-4 times more frequently than in patients without HIV infection), less prominent destructive process in the lung tissue (2 times less than in patients without HIV infection). H.pylori is the aetiological factor of PU in 62.5% of patients with IPT and 58.7% patients with HIV infection in stage C2 and IPT. The combination of H.pylori-negative PU and IPT has significantly more unfavorable prognosis compared to comorbidity of H.pylori-positive peptic ulcer and IPT. Conclusion. Diagnosis of PU, HIV infection and H.pylori-status allows defining multiple categories of comorbidity (patients with IPT and dyspeptic syndrome, patients with IPT and H.pylori-associated peptic ulcer, patients with IPT and H.pylori-negative ulcer) and multimorbidity (HIV-infected patients with IPT and H.pylori-associated ulcer, HIV-infected patients with IPT and H.pylori-negative ulcer).

Author(s):  
Lesley K Bowker ◽  
James D Price ◽  
Sarah C Smith

The ageing gastrointestinal system 352 The elderly mouth 354 Nutrition 356 HOW TO . . . Manage weight loss in older patients 357 Enteral feeding 358 HOW TO . . . Insert a fine-bore NG feeding tube 359 The ethics of clinically assisted feeding 360 Oesophageal disease 362 Dysphagia 364 Peptic ulcer disease ...


2019 ◽  
Vol 6 (2) ◽  
pp. 23-24
Author(s):  
GRAÇA MARIA CASTRO VIANA

The geriatric population is predisposed to the development of pulmonary tuberculosis (PT), both by endogenous and exogenous factors. Regarding for peptic ulcer disease (PUD) in this same age group, the clinical manifestations are related to the loss of weight and to the depreciation of the general state; a situation that provokes reactivation of PT, causing a more severe clinical picture, not only due to the association of the two pathologies, but also by the age group itself. In this case report, we present a 97-year-old woman with an unexpected association of pulmonary tuberculosis and DUP.


2000 ◽  
Vol 14 (8) ◽  
pp. 713-720 ◽  
Author(s):  
Lone Galmstrup Madsen ◽  
Peter Bytzer

The unaided clinical diagnosis of dyspepsia is of limited value in separating functional dyspepsia from clinically relevant organic causes of dyspepsia (gastric and esophageal malignancies, peptic ulcer disease and complicated esophagitis). The identification of one or more alarm features, such as weight loss, dysphagia, signs of gastrointestinal bleeding, an abdominal mass or age over 45 years may help identify patients with a higher risk of organic disease. This review summarizes the frequency of alarm symptoms in dyspeptic patients in different settings (such as the community, primary care and specialist clinics). The prevalence of alarm features in patients diagnosed with upper gastrointestinal malignancy or peptic ulcer disease is described. The probability of diagnosing clinically relevant upper gastrointestinal disease in patients presenting with alarm features and other risk factors is discussed. Alarm features such as age, significant weight loss, use of nonsteroidal anti-inflammatory drugs, signs of bleeding and dysphagia may help stratify dyspeptic patients and help optimize the use of endoscopy resources.


2001 ◽  
Vol 120 (5) ◽  
pp. A136-A137
Author(s):  
K TSAMAKIDES ◽  
E PANOTOPOULOU ◽  
D DIMITROULOPOULOS ◽  
M CHRISTOPOULO ◽  
D XINOPOULOS ◽  
...  

2001 ◽  
Vol 120 (5) ◽  
pp. A491-A491
Author(s):  
G GONZALEZSTAWINSKI ◽  
J ROVAK ◽  
H SEIGLER ◽  
J GRANT ◽  
T PAPPAS

1953 ◽  
Vol 25 (2) ◽  
pp. 173-201 ◽  
Author(s):  
William S. Haubbich ◽  
James L.A. Roth ◽  
H.L. Bockus

JMS SKIMS ◽  
2012 ◽  
Vol 15 (2) ◽  
pp. 136-140
Author(s):  
G M Gulzar ◽  
Showkat A Zargar ◽  
Muzaffar Nazir ◽  
Gul Javid ◽  
Bashir A Khan ◽  
...  

BACKGROUND: Since late 1960s, the prevalence of peptic ulcer disease and its complications has been steadily decreasing. OBJECTIVE: To ascertain the changing trends in the prevalence and complications of peptic ulcer in Kashmir. METHODS: A cohort of 10474 people aged 15-60 years in district Baramulla of Kashmir was interviewed about symptoms, complications, and surgery related to peptic ulcer. People were enquired about smoking, use of NSAIDs, H2 Receptor antagonists, proton pump inhibitors and endoscopies. All symptomatic and randomly selected group of asymptomatic people underwent esophago-gastro-cluodenoscopy. RESULTS: In symptomatic group, 286 (41.45%) people hod peptic ulcer and in asymptomatic group 24 (5.35%) had peptic ulcer. There were 71 already diagnosed cases of peptic ulcer; totaling 381. Thirty three people had surgery for peptic ulcer. The point prevalence of peptic ulcer was 3.54% and lifetime prevalence 8.96%. The highest prevalence was in 4th decade. Bleeding was seen in 23.63%, gastric outlet obstruction 4.20%, ulcer perforation 0.52%. 9.39% of peptic ulcer patients had undergone surgery. When compared to previous study in 1985 in Kashmir, there was decrease in point prevalence of 25%, in life-time prevalence of 20.14%, Gastric outlet obstruction by 51.7%, ulcer perforation by 87%, surgery rate by 60% and bleeding by a marginal 2%. CONCLUSION: Prevalence of peptic ulcerand its complications (except bleeding) are showing downward trend in Kashmir over the last 20 years. JMS 2012;15(2):136-40


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