scholarly journals An Effect of Machine Learning Based Classification Algorithms on Chronic Kidney Disease

2020 ◽  
Vol 9 (3) ◽  
pp. 2249-2256
Keyword(s):  
Machine Learning ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Prediction Models ◽  
Healthcare Systems ◽  
Medical Data ◽  
Prediction Performance ◽  
Classification Algorithms ◽  
Classification Technique ◽  
Optimal Classifier

In the recent days, the prediction models of chronic kidney disease (CKD) becomes significant in the area of decision making which is helpful in healthcare systems. Because of large amount of medical data, efficient models are required to obtain precise results and data classification algorithms can be employed to detect the presence of CKD. Recently, various machine learning (ML) dependent on data classifier technique is presented for forecasting CKD. Since numerous classification algorithms for CKD prediction exist, there is a need to investigate the prediction performance of these algorithms. This paper propose a comparative analysis of 4 data classifier technique such as deep learning (DL), decision tree (DT), random forest (RF) and random tree (RT). The process of classification technique is analyzed with the help of reputed CKD dataset attained from UCI repository. From the simulation outcomes, it is evident that the DL method achieved optimal classifier action with respect to various namely accuracy, precision and recall.

scholarly journals Machine Learning Prediction Models for Chronic Kidney Disease using National Health Insurance Claim Data in Taiwan

2020 ◽  
Author(s):  
Surya Krishnamurthy ◽  
Kapeleshh KS ◽  
Erik Dovgan ◽  
Mitja Luštrek ◽  
Barbara Gradišek Piletič ◽  
...  
Keyword(s):  
Machine Learning ◽  
Chronic Kidney Disease ◽  
Health Insurance ◽  
Kidney Disease ◽  
National Health Insurance ◽  
National Health ◽  
Performance Metrics ◽  
Prediction Models ◽  
Research Database ◽  
Number Of Patients

ABSTRACTBackground and ObjectiveChronic kidney disease (CKD) represent a heavy burden on the healthcare system because of the increasing number of patients, high risk of progression to end-stage renal disease, and poor prognosis of morbidity and mortality. The aim of this study is to develop a machine-learning model that uses the comorbidity and medication data, obtained from Taiwan’s National Health Insurance Research Database, to forecast whether an individual will develop CKD within the next 6 or 12 months, and thus forecast the prevalence in the population.MethodsA total of 18,000 people with CKD and 72,000 people without CKD diagnosis along with the past two years of medication and comorbidity data matched by propensity score were used to build a predicting model. A series of approaches were tested, including Convoluted Neural Networks (CNN). 5-fold cross-validation was used to assess the performance metrics of the algorithms.ResultsBoth for the 6 month and 12-month models, the CNN approach performed best, with the AUROC of 0.957 and 0.954, respectively. The most prominent features in the tree-based models were identified, including diabetes mellitus, age, gout, and medications such as sulfonamides, angiotensins which had an impact on the progression of CKD.ConclusionsThe model proposed in this study can be a useful tool for the policy-makers helping them in predicting the trends of CKD in the population in the next 6 to 12 months. Information provided by this model can allow closely monitoring the people with risk, early detection of CKD, better allocation of resources, and patient-centric management

scholarly journals Comparison of Machine Learning With Logistic Regression for Prediction of Chronic Kidney Disease in the Thai Adult Population

2021 ◽  
Vol 44 (4) ◽  
pp. 1-12
Author(s):  
Ratchainant Thammasudjarit ◽  
Punnathorn Ingsathit ◽  
Sigit Ari Saputro ◽  
Atiporn Ingsathit ◽  
Ammarin Thakkinstian
Keyword(s):  
Neural Network ◽  
Machine Learning ◽  
Chronic Kidney Disease ◽  
Logistic Regression ◽  
Random Forest ◽  
Kidney Disease ◽  
Decision Tree ◽  
Prediction Model ◽  
Prediction Models ◽  
The Neural Network

Background: Chronic kidney disease (CKD) takes huge amounts of resources for treatments. Early detection of patients by risk prediction model should be useful in identifying risk patients and providing early treatments. Objective: To compare the performance of traditional logistic regression with machine learning (ML) in predicting the risk of CKD in Thai population. Methods: This study used Thai Screening and Early Evaluation of Kidney Disease (SEEK) data. Seventeen features were firstly considered in constructing prediction models using logistic regression and 4 MLs (Random Forest, Naïve Bayes, Decision Tree, and Neural Network). Data were split into train and test data with a ratio of 70:30. Performances of the model were assessed by estimating recall, C statistics, accuracy, F1, and precision. Results: Seven out of 17 features were included in the prediction models. A logistic regression model could well discriminate CKD from non-CKD patients with the C statistics of 0.79 and 0.78 in the train and test data. The Neural Network performed best among ML followed by a Random Forest, Naïve Bayes, and a Decision Tree with the corresponding C statistics of 0.82, 0.80, 0.78, and 0.77 in training data set. Performance of these corresponding models in testing data decreased about 5%, 3%, 1%, and 2% relative to the logistic model by 2%. Conclusions: Risk prediction model of CKD constructed by the logit equation may yield better discrimination and lower tendency to get overfitting relative to ML models including the Neural Network and Random Forest.  

scholarly journals Machine Learning Prediction Models for Chronic Kidney Disease Using National Health Insurance Claim Data in Taiwan

Healthcare ◽  
2021 ◽  
Vol 9 (5) ◽  
pp. 546
Author(s):  
Surya Krishnamurthy ◽  
Kapeleshh KS ◽  
Erik Dovgan ◽  
Mitja Luštrek ◽  
Barbara Gradišek Piletič ◽  
...  
Keyword(s):  
Machine Learning ◽  
Chronic Kidney Disease ◽  
Health Insurance ◽  
Kidney Disease ◽  
National Health Insurance ◽  
National Health ◽  
Prediction Models ◽  
Research Database ◽  
Close Monitoring ◽  
Number Of Patients

Chronic kidney disease (CKD) represents a heavy burden on the healthcare system because of the increasing number of patients, high risk of progression to end-stage renal disease, and poor prognosis of morbidity and mortality. The aim of this study is to develop a machine-learning model that uses the comorbidity and medication data obtained from Taiwan’s National Health Insurance Research Database to forecast the occurrence of CKD within the next 6 or 12 months before its onset, and hence its prevalence in the population. A total of 18,000 people with CKD and 72,000 people without CKD diagnosis were selected using propensity score matching. Their demographic, medication and comorbidity data from their respective two-year observation period were used to build a predictive model. Among the approaches investigated, the Convolutional Neural Networks (CNN) model performed best with a test set AUROC of 0.957 and 0.954 for the 6-month and 12-month predictions, respectively. The most prominent predictors in the tree-based models were identified, including diabetes mellitus, age, gout, and medications such as sulfonamides and angiotensins. The model proposed in this study could be a useful tool for policymakers in predicting the trends of CKD in the population. The models can allow close monitoring of people at risk, early detection of CKD, better allocation of resources, and patient-centric management.

Risk Factor Identification, Classification and Prediction Summary of Chronic Kidney Disease

2020 ◽  
Vol 13 ◽  
Author(s):  
Pramila Arulanthu ◽  
Eswaran Perumal
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Disease Diagnosis ◽  
Medical Data ◽  
Machine Learning Algorithms ◽  
World Health ◽  
Medical Field ◽  
Data Set ◽  
Medical Issues ◽  
Health Organization

: The medical data has an enormous quantity of information. This data set requires effective classification for accurate prediction. Predicting medical issues is an extremely difficult task in which Chronic Kidney Disease (CKD) is one of the major unpredictable diseases in medical field. Perhaps certain medical experts do not have identical awareness and skill to solve the issues of their patients. Most of the medical experts may have underprivileged results on disease diagnosis of their patients. Sometimes patients may lose their life in nature. As per the Global Burden of Disease (GBD-2015) study, death by CKD was ranked 17th place and GBD-2010 report 27th among the causes of death globally. Death by CKD is constituted 2·9% of all death between the year 2010 and 2013 among people from 15 to 69 age. As per World Health Organization (WHO-2005) report, 58 million people expired by CKD. Hence, this article presents the state of art review on Chronic Kidney Disease (CKD) classification and prediction. Normally, advanced data mining techniques, fuzzy and machine learning algorithms are used to classify medical data and disease diagnosis. This study reviews and summarizes many classification techniques and disease diagnosis methods presented earlier. The main intention of this review is to point out and address some of the issues and complications of the existing methods. It is also attempts to discuss the limitations and accuracy level of the existing CKD classification and disease diagnosis methods.

Machine-learning algorithm as a prognostic tool in non-obstructive acute-on-chronic kidney disease in the cat

2021 ◽  
pp. 1098612X2110012
Author(s):  
Jade Renard ◽  
Mathieu R Faucher ◽  
Anaïs Combes ◽  
Didier Concordet ◽  
Brice S Reynolds
Keyword(s):  
Machine Learning ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Decision Tree ◽  
Diagnostic Performance ◽  
Clinical Signs ◽  
Learning System ◽  
Clinical Severity ◽  
Medium Term ◽  
Term Survival

Objectives The aim of this study was to develop an algorithm capable of predicting short- and medium-term survival in cases of intrinsic acute-on-chronic kidney disease (ACKD) in cats. Methods The medical record database was searched to identify cats hospitalised for acute clinical signs and azotaemia of at least 48 h duration and diagnosed to have underlying chronic kidney disease based on ultrasonographic renal abnormalities or previously documented azotaemia. Cases with postrenal azotaemia, exposure to nephrotoxicants, feline infectious peritonitis or neoplasia were excluded. Clinical variables were combined in a clinical severity score (CSS). Clinicopathological and ultrasonographic variables were also collected. The following variables were tested as inputs in a machine learning system: age, body weight (BW), CSS, identification of small kidneys or nephroliths by ultrasonography, serum creatinine at 48 h (Crea48), spontaneous feeding at 48 h (SpF48) and aetiology. Outputs were outcomes at 7, 30, 90 and 180 days. The machine-learning system was trained to develop decision tree algorithms capable of predicting outputs from inputs. Finally, the diagnostic performance of the algorithms was calculated. Results Crea48 was the best predictor of survival at 7 days (threshold 1043 µmol/l, sensitivity 0.96, specificity 0.53), 30 days (threshold 566 µmol/l, sensitivity 0.70, specificity 0.89) and 90 days (threshold 566 µmol/l, sensitivity 0.76, specificity 0.80), with fewer cats still alive when their Crea48 was above these thresholds. A short decision tree, including age and Crea48, predicted the 180-day outcome best. When Crea48 was excluded from the analysis, the generated decision trees included CSS, age, BW, SpF48 and identification of small kidneys with an overall diagnostic performance similar to that using Crea48. Conclusions and relevance Crea48 helps predict short- and medium-term survival in cats with ACKD. Secondary variables that helped predict outcomes were age, CSS, BW, SpF48 and identification of small kidneys.

scholarly journals Using machine learning models to predict the initiation of renal replacement therapy among chronic kidney disease patients

PLoS ONE ◽  
2020 ◽  
Vol 15 (6) ◽  
pp. e0233976 ◽  
Author(s):  
Erik Dovgan ◽  
Anton Gradišek ◽  
Mitja Luštrek ◽  
Mohy Uddin ◽  
Aldilas Achmad Nursetyo ◽  
...  
Keyword(s):  
Machine Learning ◽  
Chronic Kidney Disease ◽  
Renal Replacement Therapy ◽  
Kidney Disease ◽  
Replacement Therapy ◽  
Learning Models ◽  
Machine Learning Models
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