MIMICKING SOFT TISSUE TUMOUR- SPINDLE CELL LIPOMA

2021 ◽  
pp. 111-113
Author(s):  
Lahari Sampangi Ram Reddy ◽  
Indira Galidevara ◽  
Kannan R
Keyword(s):  
Spindle Cell ◽  
Complex Mixture ◽  
Variable Number ◽  
Soft Tissue Tumour ◽  
Spindle Cell Lipoma ◽  
Posterior Aspect ◽  
Spindle Cells ◽  
Tissue Tumour ◽  
The Right ◽  
Slow Growing

Spindle cell lipomas (SCL) are slow-growing benign adipocyte tumours that are most commonly seen in (1) the upper back, posterior aspect of the neck, and shoulders . Both genders are affected, but it is more (1) prevalent in males between the ages of 40 and 70 . Spindle cell lipoma is a benign tumour that is frequently confused with (1) liposarcoma. SCLs account for approximately 1.5 percent of all lipomatous tumours reported, making them uncommon . They (2) have a morphology similar to other benign and malignant fatty/spindle cell or myxoid lesions . Microscopically, it is a complex mixture of lipocytes and uniform spindle cells embedded in a mucinous matrix and traversed by (2) a variable number of birefringent collagen bres . Due to the unusual presentation and similar morphology of tumours, early diagnosis is critical; thus, diagnosis is based on clinical examination and conrmed by histopathological ndings. Because SCL has a favourable prognosis, wide local (1) excision is the treatment of choice . This is a case report of a 52-year-old male with a similar presentation in the right upper limb.

The incidence and relevance of Non-Fatty components in trunk and extremity lipomatous soft tissue masses

2021 ◽  
pp. 20201403
Author(s):  
Rupert Berkeley ◽  
Odinakachukwu Okereke ◽  
Karan Malhotra ◽  
Asif Saifuddin
Keyword(s):  
Soft Tissue ◽  
Spindle Cell ◽  
Single Case ◽  
Myxoid Liposarcoma ◽  
Histological Diagnosis ◽  
Soft Tissue Tumour ◽  
Spindle Cell Lipoma ◽  
Tissue Tumour ◽  
Soft Tissue Masses ◽  
Final Histological Diagnosis

Objectives: To determine the incidence and diagnostic relevance of non-fatty ‘solid appearing’ components within lipomatous tumours of the trunk and extremity. Methods and materials: Retrospective review of patients referred to a specialist musculoskeletal oncology service over a 12 month period with a lipomatous trunk or extremity soft tissue tumour. The presence and morphology (solitary/multifocal; homogeneous/heterogeneous; well-defined/poorly-defined) of non-fatty components was recorded based on MRI, and compared with the final histological diagnosis. Results: 213 patients with 217 lipomatous tumours were included, 119 (55.9%) males and 94 (44.1%) females with mean age of 54.6 years (range 7–93 years). Seventy-seven (35.5%) lesions arose superficial to the fascia and 139 (64.1%) deep, while a single case involved both compartments. Mean maximal tumour dimension was 94.9 mm (range 12–288 mm). Non-fatty ‘solid appearing’ components were identified in 28 (12.9%) cases, of which eight were solitary and 20 were multifocal, six had homogeneous SI and 22 had heterogeneous SI, and eight had well-defined margins while 20 had poorly-defined margins. Histological diagnosis was available in 20 of the tumours containing non-fatty components, 16 of which were benign, two intermediate grade and two malignant (a dedifferentiated liposarcoma and a myxoid liposarcoma). The commonest diagnosis was spindle cell lipoma, which accounted for 10 of 20 (50%) cases with confirmed histology. Conclusions: Non-fatty components are identified in ~13% of trunk and extremity lipomatous tumours. The majority of such lesions are benign lipoma variants, most commonly spindle cell lipoma. Advances in knowledge: Solid non-fatty components are identified in approximately 13% of lipomatous tumours referred to a specialist sarcoma service. Despite the concern that these may represent dedifferentiated liposarcomas, high-grade tumours were seen in only two cases, the commonest diagnosis being a spindle cell lipoma.

Myopericytoma of the external auditory canal and tragus

2013 ◽  
Vol 127 (8) ◽  
pp. 805-808 ◽  
Author(s):  
N A Chotey ◽  
T K Naidu ◽  
V Naidoo ◽  
J Naidoo
Keyword(s):  
Case Report ◽  
Soft Tissue ◽  
External Auditory Canal ◽  
Clinicopathological Features ◽  
Soft Tissue Tumour ◽  
Anatomical Distribution ◽  
Myoid Cell ◽  
Spindle Cells ◽  
Tissue Tumour ◽  
Slow Growing

AbstractBackground:Myopericytoma is a relatively recently described skin and soft tissue tumour that demonstrates perivascular myoid cell or pericytic differentiation. Whilst the range of anatomical locations has expanded to include visceral locations, head and neck myopericytomas are rarely documented. There have been no previous reports of aural myopericytoma.Case report:This paper reports the clinicopathological features of a biopsy-proven, slow-growing, 20 × 20 mm, polypoid myopericytoma that involved the external auditory canal and tragus in an 18-year-old woman. Excision was curative.Conclusion:Heightened clinicopathological awareness of the expanding anatomical distribution of myopericytoma is critical to its diagnosis when it presents in unusual and novel locations. Myopericytoma should be added to the range of external auditory canal neoplasms, especially those characterised by an admixture of spindle cells and a prominence of blood vessels, including those with a haemangiopericytomatous pattern.

scholarly journals Angiomyofibroblastoma of scalp: a rare soft tissue tumour at an unusual site

2020 ◽  
Vol 7 (4) ◽  
pp. 1301
Author(s):  
Sajid Hussain
Keyword(s):  
Soft Tissue ◽  
Female Genital Tract ◽  
Reproductive Age ◽  
Soft Tissue Tumour ◽  
Unusual Site ◽  
Posterior Aspect ◽  
Medical College ◽  
Tissue Tumour ◽  
Slow Growing ◽  
Reproductive Age Group

Angimyofibroblastoma is a very rare, benign mesenchymal soft tissue tumour which involves the vulvovaginal area of females of reproductive age group. These tumours are usually slow growing and painless which has a very low tendency for local recurrence. In women it is common in female genital tract, vulva, and posterior perivesical space. In men it occurs in spermatic cord. Here a report of 47 year old male patient from VMKV Medical College and Hospital, Salem was presented with a swelling in the posterior aspect of scalp from 6 months with no any associated symptoms. A preoperative diagnosis of dermoid scalp was made and patient was subjected for excision.

scholarly journals Histological and Ultrastructural Description of Benign Adipocytic Tumors in Farmed Striped Sea Bream (Lythognathus mormyrus)

Animals ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. 3413
Author(s):  
Massimo Orioles ◽  
Marco Galeotti ◽  
Pierpaolo Patarnello ◽  
Stefano Pizzolitto ◽  
Donatella Volpatti
Keyword(s):  
Spindle Cell ◽  
Giant Cells ◽  
Collagen Fibers ◽  
Sea Bream ◽  
Spindle Cell Lipoma ◽  
Marine Aquaculture ◽  
Spindle Cells ◽  
Adipocytic Tumors ◽  
Abundant Cytoplasm ◽  
The Masses

Cutaneous neoplasms affecting wild striped bream (Lythognathus mormyrus) have been recorded after their introduction in a marine aquaculture farm in the Adriatic Sea. The tumors were evident on 24% of the reared fish, showing single or multiple nodules, with a diameter ranging between 0.5–4.0 cm. Histologically, all the neoplastic lesions were located in the stratum spongiosum of the dermis and were surrounded by a thin capsule of connective tissue. The tumors were predominantly composed of adipocytes grouped and surrounded by a thin net of fibroblasts and collagen fibers. In some lipomas a mixture of adipocytes and uniform spindle cells were also observed. Fibroblasts and collagen fibers, or spindle cells, showing few mitotic figures were mainly observed in other nodules. Three of the tumors showed bands of cells with elongated nuclei. Five neoplasms differed from the classic spindle cell lipoma due to the presence of scattered giant cells. These cells presented acidophilic abundant cytoplasm with multiple hyperchromatic nuclei showing a concentric “floret-like” arrangement. The tumors were further characterized by ultrastructural observations that allowed ruling out the presence of virus-like particles within the lesions. Histological features of the masses lead to the identification of four prevalent patterns of neoplasms: lipoma, fibrolipoma, spindle cell lipoma (SCL), and atypical spindle cell-like lipoma (ASCL). The different neoplasms could arise from the transformation of mesenchymal cells of dermal origin. To the author’s knowledge, this is the first report describing key differential histological and ultrastructural features of these neoplasms in striped sea bream.

scholarly journals Spindle Cell Lipoma of the Parapharyngeal Space: First Report of a Case

2001 ◽  
Vol 80 (4) ◽  
pp. 244-250 ◽  
Author(s):  
Ingo Baumann ◽  
Florian Dammann ◽  
Hans Peter Horny ◽  
Peter Karl Plinkert
Keyword(s):  
Spindle Cell ◽  
Parapharyngeal Space ◽  
Subcutaneous Tissue ◽  
Resonance Imaging ◽  
Spindle Cell Lipoma ◽  
Lipomatous Tumor ◽  
Pharyngeal Muscles ◽  
Parapharyngeal Tumor ◽  
The Right ◽  
Total Parotidectomy

Spindle cell lipomas are usually located in the subcutaneous tissue of the back, shoulders, and neck. To our knowledge, the presence of such a tumor in the parapharyngeal space has not yet been described. We evaluated a 45-year-old man with a tender swelling of the right parotid area that had reached the submandibular area. Clinical examination and magnetic resonance imaging revealed the presence of a tumor that coated the parotid area laterally and extended into the center of the parapharyngeal space, thus causing a dislocation of the pharyngeal muscles and mucosa. We performed a total parotidectomy and submandibulectomy on the right side and extirpated the parapharyngeal tumor. We were able to spare the facial nerve, and no facial paralysis occurred. Histologic examination revealed an atypical lipomatous tumor with a remarkably large portion of spindles.

scholarly journals Left Supraclavicular Spindle Cell Lipoma

2010 ◽  
Vol 2010 ◽  
pp. 1-4 ◽  
Author(s):  
Oladejo Olaleye ◽  
Bertram Fu ◽  
Ram Moorthy ◽  
Charles Lawson ◽  
Myles Black ◽  
...  
Keyword(s):  
Spindle Cell ◽  
Excisional Biopsy ◽  
Neurological Deficits ◽  
Excision Biopsy ◽  
Low Grade ◽  
Spindle Cell Lipoma ◽  
Rare Presentation ◽  
Spindle Cells ◽  
Immuno Histochemistry ◽  
Rare Benign Tumour

Background. Spindle cell lipoma (SCL) is a benign lipomatous tumour, typically occurring in the posterior neck, shoulder or upper back of elderly males. They compose of fat, CD34 positive spindle cells, and ropey collagen on a myxoid matrix. This case highlights a rare presentation of SCL and the need for pre-operative diagnosis.Case Report. A 63-year-old gentleman presented with a pre-existing left supraclavicular mass that had recently increased in size. FNA and CT Scans were performed and results discussed in the mutidisciplinary team meeting. Excisional biopsy was recommended.Radiology. CT neck showed a left supraclavicular mass of fatty density with fine internal septations. A low-grade liposarcoma could not be excluded.Histopathology. FNA was indeterminate. Histology of specimen showed bland spindle cells with no evidence of malignancy. Immuno-histochemistry showed SCL with CD34 positivity and negative staining on CDK4 and p16.Management. Excision biopsy of the mass was performed which was technically difficult as the mass invaginated around the brachial plexus. The patient recovered well post-operatively with no neurological deficits.Conclusion. Spindle cell lipoma is a rare benign tumour and a pre-operative diagnosis based on the clinical context, imaging and immuno-histochemistry is crucial to management.

scholarly journals Rare Occurrence of Lip Spindle Cell Lipoma

2015 ◽  
Vol 2015 ◽  
pp. 1-3
Author(s):  
Sandra Girgis ◽  
Leo Cheng
Keyword(s):  
Salivary Gland ◽  
Spindle Cell ◽  
Minor Salivary Gland ◽  
Surgical Excision ◽  
Spindle Cell Lipoma ◽  
Lower Lip ◽  
Salivary Gland Tumours ◽  
Minor Salivary Gland Tumour ◽  
A Minor ◽  
Slow Growing

Spindle cell lipoma (SCL) is a rare distinct variant of lipoma, which presents as a painless, circumscribed, slow-growing, superficial lesion on the lip and can mimic a minor salivary gland tumour. We present a slow growing lower lip lesion and its management.Case Report. A 38-year-old female gave an eight-year history of a slow-growing mass on her lower lip with intermittent change in size. She presented with a submucosal nodule and thin overlying mucosa adjacent to the vermilion border. Surgical excision was carried as the diagnostic and therapeutic approach.Conclusion. Lip SCL is rare, and surgical excision is advocated in order to exclude underlying pathology and minor salivary gland tumours.

scholarly journals Pleomorphic lipoma: A rare entity

2021 ◽  
Vol 8 (4) ◽  
pp. 515-517
Author(s):  
Goutami Das Nayak ◽  
Shushruta Mohanty ◽  
Meenakshi Mohapatro
Keyword(s):  
Spindle Cell ◽  
Histopathological Diagnosis ◽  
Spindle Cell Lipoma ◽  
Soft Tissue Tumours ◽  
Pleomorphic Lipoma ◽  
Atypical Cells ◽  
Posterior Neck ◽  
Subcutaneous Mass ◽  
Slow Growing ◽  
Malignant Soft Tissue

Pleomorphic lipoma is a rare neoplasm that is considered as a variant of spindle cell lipoma. It predominantly occurs in the dermis or subcutis of the posterior neck, upper back, and shoulders. Pleomorphic lipoma may clinically present as a slow-growing and well-circumscribed subcutaneous mass. Though it is a benign tumour it may contain atypical cells for which it may mimick sarcoma or other malignant soft tissue tumours. So histopathological diagnosis is vital for preventing unnecessary surgery. Here we report a case of a pleomorphic lipoma on upper back in a 55yr old patient.

scholarly journals Tail in the duodenum

2018 ◽  
Vol 5 (7) ◽  
pp. 2676
Author(s):  
Sruthi Ranganathan ◽  
T. Mohanapriya ◽  
K. Balaji Singh
Keyword(s):  
Plasma Cells ◽  
Abdominal Cavity ◽  
Complete Resection ◽  
Soft Tissue Tumour ◽  
Inflammatory Myofibroblastic Tumour ◽  
Radiological Imaging ◽  
Spindle Cells ◽  
Tissue Tumour ◽  
Children And Young Adults ◽  
Locally Recurrent

Inflammatory myofibroblastic tumour, commonly called as pseudotumor is a soft tissue tumour, commonly occurring in children and young adults and very rarely in elderly. Lungs are the most commonly affected site but sometimes it can occur in retroperitoneum and abdominal cavity. It contains spindle cells, myofibroblasts, lymphoctyes, plasma cells, and histiocytes. It is a non-encapsulated lesion. The pathogenesis of IMT remains unclear, although various allergic, immunogenic infectious mechanisms have been postulated. They are locally recurrent (15-37%) and rarely metastasize (<5%).  IMT features mimcs malignancy on UGIscopy and radiological imaging and hence surgical exploration and complete resection is required for diagnosis and treatment. The worldwide incidence of IMT is 0.04- 0.7%. Here is a case of inflammatory myofibroblastic tumour in duodenum presented with complaints of vomiting and melena.

scholarly journals Retrospective analysis of 73 cases of elastofibroma

2020 ◽  
Vol 102 (2) ◽  
pp. 84-93
Author(s):  
R Haihua ◽  
W Xiaobing ◽  
P Jie ◽  
H Xinxin
Keyword(s):  
Soft Tissue ◽  
Age At Onset ◽  
Disease Onset ◽  
Pathological Examination ◽  
Soft Tissue Tumour ◽  
Tissue Tumour ◽  
Short And Long Term ◽  
The Right

Objective Elastofibroma is a rare soft-tissue tumour. This study retrospectively analysed and summarised the clinical, imaging and typical pathological features, together with the short- and long-term surgical outcomes of patients with pathologically confirmed soft-tissue elastofibroma to improve their management. Materials and methods We enrolled 73 patients with pathologically confirmed soft-tissue elastofibroma from January 2010 to December 2018. The general, clinical, diagnostic and treatment-related data, operation notes, pathological examination results and follow-up status were obtained by reviewing inpatient medical records. Disease onset age, sex, tumour location and size were statistically analysed using the chi square and rank sum tests. Results A total of 90 lesions from 73 patients were examined. Among these, 56 patients had single lesions: 27 were under the right scapula, 26 were under the left scapula, 1 at the umbilicus, 1 on the aortic valve, 1 on the right hip and 17 at the bilateral inferior angles of the scapula. The average age at onset was 56.4 years (range: 6–82 years). The male-to-female incidence ratio was about one to three. Tumour diameter and follow-up duration ranged from 2cm to 12cm and from one month to nine years, respectively; recurrence was not observed. The main postoperative complication was wound effusion, occurring in 24 sites among the 90 lesions, corresponding to an incidence rate of 26.7%. Conclusions A correct diagnosis of elastofibroma can be made prior to surgical resection by examining typical clinical features and characteristic imaging findings. Short- and long-term outcomes of local excision are good, with no further recurrence.

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