scholarly journals PRIMARY PANCREATIC LYMPHOMA WITH HERPES ZOSTER ASSOCIATED ACUTE PANCREATITIS: A CASE REPORT AND REVIEW OF LITERATURE.

2020 ◽  
pp. 49-51
Author(s):  
Vikram Chaturvedi ◽  
Rituparna Chaturvedi ◽  
Sharmistha Debnath ◽  
Abhishek Mishra

Primary pancreatic lymphoma (PPL) is an extremely rare disease, with few cases reported in literature. Clinical manifestations are usually nonspecific and mimic other pancreatic diseases. Owing to paucity of data and experience of PPL, clinico-pathological features, differential diagnosis, optimal treatment and overall outcomes are not well known. Varicella zoster virus (VZV) is known to cause varicella in children and herpes zoster in adults. Acute pancreatitis caused by VZV is a rare and serious complication, with immunocompromised individuals being primarily affected. We report a case of VZV associated acute pancreatitis in a patient who was diagnosed and treated for primary pancreatic lymphoma, thus rendering her immunocompromised and susceptible to developing infectious pancreatitis. A 56 year old female patient presented with recurrent vomiting, upper abdominal pain and hyperaesthesia in the right upper quadrant of 2 days duration. Following admission her right sided abdominal pain worsened (stabbing pain) and a diagnosis of acute pancreatitis was confirmed based on elevated serum amylase levels and CT scan findings of pancreatic enlargement. The patient was managed conservatively with intravenous fluids, antibiotics, analgesics and topical acyclovir ointment. The patient continues to be asymptomatic after 5 years of follow up. Though extremely rare, a diagnosis of herpes zoster pancreatitis should be considered in such patients, and prompt treatment initiated to prevent further deterioration and to minimize mortality. Core tip: Primary pancreatic lymphoma is in itself a very rare disease, and our patient having presented with herpes zoster associated acute pancreatitis in a background of PPL makes this case even rarer. This is probably the first case report of herpes zoster associated acute pancreatitis in an immunocompromised patient due to primary pancreatic lymphoma.

PEDIATRICS ◽  
1992 ◽  
Vol 90 (4) ◽  
pp. 624-626
Author(s):  
THOMAS M. BERGER ◽  
WALTER J. COOK ◽  
AENGUS S. O'MARCAIGH ◽  
DONALD ZIMMERMAN

A variety of drugs including certain antibiotics have been implicated in causing acute pancreatitis.1 So far, there have been three reported cases in adults in which erythromycin was identified as a possible cause of acute pancreatitis.2-4 We report the first case of erythromycin-induced acute pancreatitis in childhood. We suggest a possible pathophysiological mechanism based on the known motilin agonist properties of erythromycin. CASE REPORT A 12-year-old girl was brought to the Emergency and Trauma Unit, with acute, crampy abdominal pain and vomiting. These symptoms had started 1 hour earlier, approximately 30 minutes after the deliberate ingestion of 20 tablets of erythromycin (Erythromycin Base Filmtab, 250 mg, Abbot Laboratories, Pharmaceutical Products Division, North Chicago, IL) after an argument with her parents and her boyfriend.


2021 ◽  
Vol 19 ◽  
pp. 205873922110212
Author(s):  
Nan Zhao ◽  
Yulan Geng ◽  
Yexian Li ◽  
Lijuan Liu ◽  
Yanjia Li ◽  
...  

Herpes zoster (HZ), caused by the varicella-zoster virus, is an infectious skin disease that rarely recurs after initial presentation. The mechanism underlying HZ recurrence is currently under investigation. In this article, we report a case of HZ relapse within 1 month. Analysis of patient’s clinical manifestations, histopathological features, and flow cytometry results indicated that the absolute and percentage values of B cells were below the lower limit. We hypothesized that the patient had abnormal humoral immune function, which may be one reason leading to the HZ relapse within 1 month. The findings of this case will serve as useful reference for HZ recurrence for clinicians. This case was impactful and added to the literature on HZ recurrence.


2012 ◽  
Vol 4 (1) ◽  
pp. e2012005
Author(s):  
Valentina Bozzoli ◽  
Maria Chiara Tisi ◽  
Luigi Pianese ◽  
Stefano Tumini ◽  
Vittoria Rufini ◽  
...  

Primary pancreatic lymphoma (PPL) is an extremely rare disease which occurs in pancreas, accounts for less than 1% of extra-nodal malignant lymphomas and 0,5% of cases of pancreatic masses. We report the case of PPL in a 15 year-old boy suffering from Maturity onset Diabetes of the young type 3 (MODY3) diagnosed at the age of 1 year


2019 ◽  
Vol 12 (4) ◽  
pp. e229208
Author(s):  
Caroline Annette Erika Bachmeier ◽  
Adam Morton

Serum lipase and amylase are commonly requested in individuals presenting with abdominal pain for investigation of acute pancreatitis. Pancreatic hyperenzymaemia is not specific for acute pancreatitis, occurring in many other pancreatic and non-pancreatic conditions. Where persistent elevation of serum lipase and amylase occurs in the absence of a diagnosed cause or evidence of laboratory assay interference, ongoing radiological assessment for pancreatic disease is required for 24 months before a diagnosis of benign pancreatic hyperenzymaemia can be made. We report a case of a 71-year-old man with epigastric pain and elevated serum lipase levels. He was extensively investigated, but no pancreatic disease was detected. He is asymptomatic, but serum lipase levels remain elevated 18 months after his initial presentation.


1970 ◽  
Vol 2 (1) ◽  
pp. 67-70 ◽  
Author(s):  
Abhimanyu Jha ◽  
Gita Sayami ◽  
Deepti Adhikari

Uterine lipoleiomyosarcoma is a heterologous sarcoma composed of variable proportions of malignant lipoblasts histologically corresponding to well differentiated liposarcoma and malignant smooth muscle cells corresponding to leiomyosarcoma. Finding of benign lipomatous component in a typical leiomyoma (lipoleiomyoma) is not an uncommon, however, lipoleiomyosarcoma is an extremely rare malignant tumor and only very few cases have been reported so far. We report a case of lipoleiomyosarcoma of uterine corpus in a postmenopausal woman presenting with lower abdominal pain and abdominal mass. Diagnosis of lipoleiomyosarcoma was confirmed by histopathological examination of hysterectomy specimen. This is the first case of lipoleiomyosarcoma of uterus reported from Nepal. Keywords: Lipoleiomyosarcoma, uterus, histopathology, unusual case.   doi:10.3126/njog.v2i1.1482    N. J. Obstet. Gynaecol Vol. 2, No. 1, p. 67 - 70 May -June 2007


2020 ◽  
Vol 72 ◽  
pp. 533-536
Author(s):  
Lucas Faraco Sobrado ◽  
Lucas Ernani ◽  
Daniel Reis Waisberg ◽  
Luiz Augusto Carneiro-D’Albuquerque ◽  
Wellington Andraus

2018 ◽  
Vol 2018 ◽  
pp. 1-4 ◽  
Author(s):  
Venkata Rajesh Konjeti ◽  
Gerald M. Hefferman ◽  
Sravanthi Paluri ◽  
Prerna Ganjoo

Primary pancreatic lymphoma (PPL) is of very rare occurrence as an extra nodal site of Non-Hodgkin’s lymphoma (NHL). It represents less than 1% of NHL. Out of which Burkitt lymphoma of pancreas is of a rare presentation. It usually occurs in children and presenting in adults is uncommon. The prevalence of pancreatic Burkitt lymphoma is not known as the incidence is significantly low. Clinical features of PPL are predominantly nonspecific and can become difficult with associated inflammation of pancreas. Differentiation of lymphoma to adenocarcinoma is important as chemotherapy is the main stay of treatment in lymphoma. We report a case of 68-year-old female who presented with nonspecific symptoms and was found to have obstructive jaundice secondary to pancreatic head neoplasm which was proved to be pancreatic Burkitt lymphoma which is a rare presentation.


2021 ◽  
Vol 74 (1-2) ◽  
pp. 33-37
Author(s):  
Sanja Jakovljevic ◽  
Ljuba Vujanovic ◽  
Dejan Ogorelica ◽  
Aleksandra Fejsa-Levakov ◽  
Jasmina Sekulic

Introduction. Grover?s disease is characterized by pruriginous polymorphic rash with a variable course and duration. Although the etiology is still unknown, the disease is often associated with other dermatoses, malignant diseases, use of certain medications, as well as immunosuppression. Case Report. We report a case of a 70-year-old male patient who was referred for examination to the Clinic of Dermatovenereology Diseases, Clinical Center of Vojvodina, due to a rash that lasted for nine months. The first lesions on the skin appeared around the nipples as exudative eczematous plaques. A few months later, identical lesions appeared on the lower legs. During treatment with systemic antihistamines and topical corticosteroids, there were episodes of transient improvements and re-exacerbations. In the meantime, erythematous brownish, round and oval papules appeared on the abdomen and the back, accompanied by intense itch. Laboratory findings revealed eosinophilia and elevated serum immunoglobulin E levels. A skin biopsy of the back lesion was performed and the histopathological examination confirmed the diagnosis of Grover?s disease. After the systemic treatment using corticosteroids and antihistamines, with gradual dose reduction and application of topical corticosteroids and emollients, complete regression of the skin lesions was achieved. Conclusion. Since the clinical manifestations of the disease may be nonspecific and discrete, dermatopathological analysis is of crucial importance in making the correct diagnosis. In patients with atopy, the treatment with systemic corticosteroids, antihistamines and topical agents may lead to regression of skin lesions with a significant improvement in the quality of life.


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