A RARE CASE OF EXTRAOCULAR ORBITAL LYMPHOMA IN A YOUNG PATIENT

2021 ◽  
pp. 71-72
Author(s):  
M. Deori ◽  
J. J. Kuli

Orbital lymphoma refers to a lymphoma that commonly involves the conjunctiva, lacrimal gland, eyelid and ocular musculature. Primary non1 Hodgkin's lymphoma (NHL) of the orbit is a rare subset, representing only 1% of all NHL and 8-10% of extranodal NHL. We report a case of 24 year old female presented with redness, swelling, an intermittent pain and gradual protrusion of the right eye (RE) since 6 months. Her vision in RE was 6/60 and in Left eye (LE) 6/6. Intraocular pressure (IOP) was 16 mmHg in Both Eye. On examination, RE was proptosed 30mm approximately. Extraocular movement were restricted in all gazes, conjunctiva was chemosed and congested. LE was within normal limits. No lymph nodes were palpable. Ultrasonography of the right orbit showed a mass in the lateral aspect in extraconal space extending to the superior, lateral and retrobulbar region. CT scan of the right orbit showed a mass encasing the extraocular muscles and displacement of the optic nerve. FNAC reports were suggestive of non-Hodgkin's Lymphoma of the right orbit. She was given 6 cycles of RCHOP regime which includes (rituximab, cyclophosphamide, hydroxydaunorubicin, oncovin and prednisolone). Follow-up during each cycle of chemotherapy was done and showed good response initially. Even though rare, primary orbital NHL should be kept in considerat Conclusion- ion in a young female patient with slow growing unilateral Proptosis. After imaging & diagnostic biopsy, patient should be immediately staged & treated. Early diagnosis and treatment improves survival.

2010 ◽  
Vol 22 (3-4) ◽  
pp. 131-139 ◽  
Author(s):  
Paolo Caffarra ◽  
Letizia Concari ◽  
Simona Gardini ◽  
Sabrina Spaggiari ◽  
Francesca Dieci ◽  
...  

A patient who suffered a transient global amnesia (TGA) attack underwent regional cerebral blood flow (rCBF) SPECT imaging and neuropsychological testing in the acute phase, after one month and after one year. Neuropsychological testing in the acute phase showed a pattern of anterograde and retrograde amnesia, whereas memory was within age normal limits at follow up. SPECT data were analysed with a within subject comparison and also compared with those of a group of healthy controls. Within subject comparison between the one month follow up and the acute phase detected increases in rCBF in the hippocampus bilaterally; further rCBF increases in the right hippocampus were detected after one year. Compared to controls, significant hypoperfusion was found in the right precentral, cingulate and medial frontal gyri in the acute phase; after one month significant hypoperfusion was detected in the right precentral and cingulate gyri and the left postcentral gyrus; after one year no significant hypoperfusion appeared. The restoration of memory was paralleled by rCBF increases in the hippocampus and fronto-limbic-parietal cortex; after one year neither significant rCBF differences nor cognitive deficits were detectable. In conclusion, these data indicate that TGA had no long lasting cognitive and neural alterations in this patient.


2015 ◽  
Vol 9 (11-12) ◽  
pp. 834 ◽  
Author(s):  
Mohamed Tarchouli ◽  
Adil Boudhas ◽  
Moulay Brahim Ratbi ◽  
Mohamed Essarghini ◽  
Noureddine Njoumi ◽  
...  

Adrenal hemangioma is an extremely rare benign and non-functioning neoplasm of the adrenal gland. We report a case of a 71-year-old woman admitted for intermittent abdominal pain and abdominal distension associated with vomiting and chronic constipation for 5 years. Physical examination revealed a large abdominal mass. Both computed tomography scan and magnetic resonance imaging suggested hemangioma in the right lobe of the liver. Laboratory examinations and tumour markers were within normal limits, except for hypochromic microcytic anemia. The mass was removed intact by conventional surgery and histopathology revealed a cavernous hemangioma of the adrenal gland with no signs of malignancy. Surgical resection was curative, with no recurrence at the 2-year follow-up.


2000 ◽  
Vol 30 (4) ◽  
pp. 492 ◽  
Author(s):  
Sang Bum Kang ◽  
Seung Won Jin ◽  
Eun Kyeong Lee ◽  
Yong Hyun Park ◽  
Yong Ho Choi ◽  
...  

1991 ◽  
Vol 12 (3) ◽  
pp. 464-467 ◽  
Author(s):  
J. J. MONSUEZ ◽  
J. FRIJA ◽  
L. HERTZ-PANNIER ◽  
J. M. MICLEA ◽  
J. M. EXTRA ◽  
...  

BMJ Open ◽  
2018 ◽  
Vol 8 (9) ◽  
pp. e018120
Author(s):  
Inge M Krul ◽  
Annemieke W J Opstal-van Winden ◽  
Josée M Zijlstra ◽  
Yolande Appelman ◽  
Sanne B Schagen ◽  
...  

IntroductionHodgkin’s lymphoma (HL) has become the prototype of a curable disease. However, many young survivors suffer from late adverse effects of treatment. Both chemotherapy (CT) and radiotherapy (RT) may induce primary ovarian insufficiency (POI), which has been associated with reduced bone mineral density (BMD), neurocognitive dysfunction and possibly cardiovascular disease (CVD). While the general assumption is that POI increases CVD risk, other hypotheses postulate reverse causality, suggesting that cardiovascular risk factors determine menopausal age or that biological ageing underlies both POI and CVD risk. None of these hypotheses are supported by convincing evidence. Furthermore, most studies on POI-associated conditions have been conducted in women with early natural or surgery-induced menopause with short follow-up times. In this study, we will examine the long-term effects of CT-induced and/or RT-induced POI on BMD, cardiovascular status, neurocognitive function and quality of life in female HL survivors.Methods and analysisThis study will be performed within an existing Dutch cohort of HL survivors. Eligible women were treated for HL at ages 15–39 years in three large hospitals since 1965 and survived for ≥8 years after their diagnosis. Women visiting a survivorship care outpatient clinic will be invited for a neurocognitive, cardiovascular and BMD assessment, and asked to complete several questionnaires and to provide a blood sample. Using multivariable regression analyses, we will compare the outcomes of HL survivors who developed POI with those who did not. Cardiovascular status will also be compared with women with natural POI.Ethics and disseminationThis study has been approved by the Institutional Review Board of the Netherlands Cancer Institute and has been registered at ‘Toetsingonline’ from the Dutch Central Committee on Research involving Human Subjects (file no. NL44714.031.13). Results will be disseminated through peer-reviewed publications and will be incorporated in follow-up guidelines for HL survivors.


2005 ◽  
Vol 133 (9-10) ◽  
pp. 433-437
Author(s):  
Radoje Colovic ◽  
Natasa Colovic ◽  
Nikica Grubor ◽  
Vladimir Radak ◽  
Marijan Micev ◽  
...  

Angiomyolipomas are relatively frequent tumors of the kidney. It is believed that about 10 million people worldwide have such a tumor. About 1/10 of these 10 million are patients who suffer from tuberous sclerosis. The tumors are frequently bilateral, slow growing, and usually a symptomatic, as well as being rare in children. Due to the benign nature of angiomyolipomas, surgical treatment and embolisation of the tumors are generally not recommended, unless renal function is endangered, the symptoms are severe, or the kidney in question becomes completely dysfunctional. This is particularly the case in patients with tuberous sclerosis in whom these tumors are either already bilateral or may become so. We present a 24-year-old woman with tuberous sclerosis in whom bilateral kidney tumors were diagnosed 7 years earlier and in whom we carried out a left nephrectomy of a 5300 gram angiomyolipoma, which caused pain and complete loss of function. Although timorous, the right kidney was functional, so it was left untouched. After an uneventful recovery, a close follow-up was recommended, as well as HLA typing, as it is highly probable that the right kidney will gradually become inadequate or completely dysfunctional, so that haemodialysis and/or kidney transplantation along with nephrectomy will become necessary.


10.3823/2437 ◽  
2017 ◽  
Vol 10 ◽  
Author(s):  
Cristiane Nobre Silva ◽  
Diane Sousa Sales ◽  
Carla Suellen Pires De Sousa ◽  
Antonio Dean Barbosa Marques ◽  
Priscila França De Araújo ◽  
...  

Diagnosis and treatment of Hodgkin’s lymphoma introduce a new routine, and the habitual life of the young adult is interrupted because the treatment imposes on patients withdrawing from their environment, their productive activities, their relatives and their daily life. The aim of the present is study is to understand the reality of the young adult carrier of Hodgkin’s lymphoma in the face of treatment. This is a qualitative study; subjects were patients diagnosed with Hodgkin’s lymphoma at a reference hospital in northeastern Brazil. Inclusion criteria were being undergoing treatment or follow-up of Hodgkin’s lymphoma, and aged 18 to 35 years. The information was collected through an interview at the home of each subject in the period from August and September 2015. The interviews were recorded, transcribed in full and analyzed through thematic analysis. The study was approved by the Research Ethics Committee. The subjects went through a rather individual pathway to discover the disease. After reading the interviews, the following category emerged: Impact and changes in life with cancer. They feel the impact of cancer and of the process of illness and treatment that promote physical and social changes. They reveal the coping of the disease with liveliness, and present strategies for this process, such as the support of family and friends. They recognize the existence of difficult moments and face situations of death, but they show intention to return to their daily activities and have perspectives for cure. 


Cancer ◽  
1998 ◽  
Vol 82 (3) ◽  
pp. 576-582 ◽  
Author(s):  
Mario Lazzarino ◽  
Ester Orlandi ◽  
Catherine Klersy ◽  
Cesare Astori ◽  
Ercole Brusamolino ◽  
...  

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