scholarly journals AN AYURVEDIC MANAGEMENT OF VARICOSE ULCER: A CASE STUDY

2020 ◽  
pp. 1-2
Author(s):  
Manju. P ◽  
T Thomas ◽  
Sindhu Das H
Keyword(s):  
Lymph Node ◽  
Inguinal Lymph Node ◽  
Ulcer Patient ◽  
Medial Malleolus ◽  
Lymph Node Enlargement ◽  
Varicose Ulcer ◽  
Healing Wound ◽  
Treatment Procedures

A male patient aged 37 yrs came to Salyatantra OPD of Sree Narayana Institute of Ayurvedic Studies & Research Hospital, Puthoor, Kollam with complaints of a non-healing wound on left medial malleolus since 6 months. Discharge and itching around wound since 10 days. Pain over inguinal region since 2 days and came here for better management. On examination there was a vertically oval shaped ulcer with slopping edge and the floor was covered with red granulation tissue and white margin on left medial malleolus. On palpation there was temperature rise and tenderness and inguinal lymph node enlargement. The diagnosis was confirmed as varicose ulcer. Patient was treated with Jalaukavacharana for 2 days, Yogavasthi and Avagaha and dressing with Jathyadi Ghrita and crepe bandaging for 9 days along with internal medication. The wound responded well with each treatment procedures. The wound was completely healed. Follow up was done on 7th day and 14th day of discharge. There was complete closure wound. No reappearance of disease since three months. Thus this patient was successfully treated with this Ayurvedic protocol without any recurrence and complications.

scholarly journals AN AYURVEDIC MANAGEMENT OF VARICOSE ULCER: A CASE STUDY.

2020 ◽  
pp. 1-2
Author(s):  
Manju. P ◽  
T Thomas ◽  
Sindhu Das H
Keyword(s):  
Lymph Node ◽  
Inguinal Lymph Node ◽  
Ulcer Patient ◽  
Medial Malleolus ◽  
Lymph Node Enlargement ◽  
Varicose Ulcer ◽  
Healing Wound ◽  
Treatment Procedures

A male patient aged 37 yrs came to Salyatantra OPD of Sree Narayana Institute of Ayurvedic Studies & Research Hospital, Puthoor, Kollam with complaints of a non-healing wound on left medial malleolus since 6 months. Discharge and itching around wound since 10 days. Pain over inguinal region since 2 days and came here for better management. On examination there was a vertically oval shaped ulcer with slopping edge and the floor was covered with red granulation tissue and white margin on left medial malleolus. On palpation there was temperature rise and tenderness and inguinal lymph node enlargement. The diagnosis was confirmed as varicose ulcer. Patient was treated with Jalaukavacharana for 2 days, Yogavasthi and Avagaha and dressing with Jathyadi Ghrita and crepe bandaging for 9 days along with internal medication. The wound responded well with each treatment procedures. The wound was completely healed. Follow up was done on 7th day and 14th day of discharge. There was complete closure wound. No reappearance of disease since three months. Thus this patient was successfully treated with this Ayurvedic protocol without any recurrence and complications.

scholarly journals Mammary Gland Malignant Myoepithelioma in a Domestic Rabbit (Oryctolagus cuniculus)

2019 ◽  
Vol 47 ◽  
Author(s):  
Halana Do Carmo Silva ◽  
Avisa Rodrigues De Oliveira ◽  
Rodrigo Dos Santos Horta ◽  
Betânia Souza Moereira ◽  
Tatiany Luiza Silveira ◽  
...  
Keyword(s):  
Mammary Gland ◽  
Lymph Node ◽  
Oryctolagus Cuniculus ◽  
Blood Count ◽  
Complete Blood Count ◽  
Inguinal Lymph Node ◽  
Serum Biochemistry ◽  
Domestic Rabbit ◽  
Mitotic Figures

Background: Malignant myoepithelioma is a rare neoplasm in humans and rats, poorly reported in dogs and not previously described in rabbits. This study aimed to report a case of malignant mammary myoepithelioma in a domestic rabbit (Oryctolagus cuniculus). Case: A domestic, hybrid, female, entire, nulliparous, seven-year-old rabbit was attended in the Veterinary Hospital Prof. Ricardo Alexandre Hippler at Universidade Vila Velha (UVV) with a history of apathy, lethargy and anorexia. In the clinical examination a 5 cm tumour was observed in the right abdominal mammary gland (M2), along with floating smaller lesions in M1 and M3. There were no palpable abnormalities in the axillary and inguinal lymph nodes. Complete blood count and serum biochemistry were within the normal range. Fine needle aspiration was performed for cytopathological evaluation of the tumour in M2 and it was suggestive of a malignant glandular neoplasm, with probable epithelial origin. Complete staging included chest and abdominal radiographs, but they were unremarkable. The patient was submitted to a right unilateral mastectomy, involving resection of the inguinal lymph node. The sample was sent to the Laboratory of Animal Pathology of UVV for routine histological evaluation. Histopathological evaluation in M2 was compatible with malignant myoepithelioma based on the literature, while nodules in M1 and M3 were classified as mammary cysts. The inguinal lymph node showed no significant abnormalities. An immunohistochemical panel was performed in the Comparative Pathology Laboratory of the Institute of Biological Sciences of the Universidade Federal de Minas Gerais (UFMG), using immunomarkers (pan-cytokeratin, p63 and vimentin) to characterize the tumour and confirm its diagnosis. Immunohistochemistry revealed expression of p63, and was negative for pan-cytokeratin and vimentin, which confirmed the myoepithelial origin, without involvement of the epithelial compartment. Clinical follow-up was recommended every 2-3 months, including abdominal ultrasonography, chest X-rays, complete blood count and serum biochemistry. Ultrasonography showed thinning of the uterine wall, dilation of 3.7 cm in diameter and presence of endometrial cysts of varied sizes, around 0.7 cm. Neutering was recommended but it was not elected by the pet´s responsible. These findings remained stable throughout the follow-up, which was greater than 405 days.Discussion: This is the first report of a malignant myoepithelioma in rabbit, with a detailed description of the clinical, surgical, pathological and immunophenotypic aspects of this neoplasm in this species. This is a tumour characterized by proliferation of epithelioid to spindle-like myoepithelial cells, as observed in this case, forming an extensive and well delimited solid area with marked central necrosis, compatible with what has already been described in the literature on bitches and women. As observed in this case, the neoplastic cells usually exhibit moderate cellular and nuclear pleomorphism, moderate anisocytosis and anisokaryosis, and several mitotic figures; different from what is observed in women, in which mitotic figures vary from small to moderate amount. Neoplasia and mammary cysts were removed by mastectomy, and the owner choose not to castrate the animal. On ultrasonography, after 12 months, the endometrium presented structures similar to cysts and was hyperplastic, which is commonly reported in association to mammary neoplasia. Nervertheless, the pet´s owner choose not to spay the rabbit and the lesions were stable on imaging follow-up

High-grade serous cancer of undetermined primary origin presenting as solitary inguinal lymph node enlargement

2021 ◽  
Vol 14 (4) ◽  
pp. e239185
Author(s):  
Karen Dam ◽  
Frederik Peeters ◽  
Didier Verhoeven ◽  
Valerie Duwel
Keyword(s):  
Lymph Node ◽  
Unusual Case ◽  
Inguinal Lymph Node ◽  
Complete Response ◽  
Serous Carcinoma ◽  
Pathological Examination ◽  
High Grade ◽  
Positron Emission ◽  
Lymph Node Enlargement ◽  
Primary Origin

A 62-year-old woman presented with unilateral inguinal lymphadenopathy, existing for several months. As it was initially thought to be lymphoma, the lymph node was resected. Pathology, however, revealed a metastasis of a high-grade papillary serous cancer, according to its stainings, most likely ovarian in origin. Further staging showed lymphadenopathies in the inguinofemoral, para-aortic and mediastinal regions. Consequently, the multidisciplinary oncologic meeting advised a diagnostic laparoscopy which showed no macroscopic spread within the abdomen. Pathological examination of biopsies as well as both ovaries showed no sign of ovarian cancer. The patient received standard chemotherapy, that is, carbo-Taxol-Avastin, to which she showed complete response after three cycles as shown on positron emission tomography–CT. A review of existing literature showed that this is a very unusual case of high-grade serous carcinoma, where no site of origin could be found.

scholarly journals The Pedicled Flap of Adductor Longus, a New Technique for Inguinal Reconstruction

2021 ◽  
Vol 8 ◽  
Author(s):  
Hong Zhang ◽  
Zhenfeng Li ◽  
Jianmin Li ◽  
Lei Zhu ◽  
Yakubu Ibrahim
Keyword(s):  
Lymph Node ◽  
Lymph Node Dissection ◽  
Inguinal Lymph Node ◽  
Pedicled Flap ◽  
Local Resection ◽  
Inguinal Region ◽  
Node Dissection ◽  
Inguinal Lymph Node Dissection ◽  
Adductor Longus

Introduction: Reconstruction surgeries of the inguinal area pose a challenge for oncological and orthopedic surgeons, especially after radical local resection (RLR), radical inguinal lymph node dissection (RILND), or both. Although numerous surgical procedures have been reported, there is no report about a pedicle adductor longus flap method. The aim of this work is to show our experience about inguinal reconstruction with pedicled adductor longus flap and associated outcomes.Patients and Methods: A retrospective study of 16 patients with localized inguinal region interventions and reconstructed by adductor longus flap from March 2016 to July 2020. Patients' average age was 60.0 years (range = 38–79 years) and had postoperative follow-up of 10 months (ranging 2–19 months). All patients had unilateral inguinal region involvement—seven cases on the left and nine cases on the right. The patients' clinical course, operative course, and postoperative follow-up data were evaluated.Results: All 16 patients recovered well post-operatively and did not require any re-intervention. Four patients experienced negligible discomfort around the groin area. Five patients experienced a minor strength deficit in thigh adduction compared with that of preoperative strength in the same or contralateral leg. The aforementioned complications resolved during the postoperative course and had no functional impact on their activity of daily living. All adductor longus flaps survived, completely filled the inguinal dead space, and wounds healed uneventfully within 3 weeks except for three patients who suffered delayed wound healing for more than 4 weeks. Other common complications such as infection, seroma, or wound dehiscence were not encountered in this series.Conclusion: The adductor longus flap is a reliable alternative method for inguinal region reconstruction following radical local resection (RLR), radical inguinal lymph node dissection (RILND), or both.

scholarly journals Mediastinal lymph node enlargement in idiopathic pulmonary fibrosis: relationships with disease progression and pulmonary function trends

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Giacomo Sgalla ◽  
Anna Rita Larici ◽  
Nicoletta Golfi ◽  
Mariarosaria Calvello ◽  
Alessandra Farchione ◽  
...  
Keyword(s):  
Lymph Node ◽  
Idiopathic Pulmonary Fibrosis ◽  
Pulmonary Fibrosis ◽  
Lymph Nodes ◽  
Ct Scan ◽  
Disease Progression ◽  
Mediastinal Lymph Node ◽  
Mediastinal Lymph Nodes ◽  
Lymph Node Enlargement

Abstract Background and objectives Evidence of mediastinal Lymph Node Enlargement (LNE) on CT scan is a common finding in idiopathic pulmonary fibrosis (IPF). We sought to investigate whether the involvement of mediastinal lymph nodes is associated with accelerated disease progression, and explored the changes occurring in mediastinal lymph nodes during the radiological follow up of these patients. Methods This retrospective study included IPF patients referred to a single ILD centre in Italy. A consensus-based assessment of mediastinal LNE on chest CT scan was performed by two thoracic radiologists. Kaplan-Meier curves and multivariate Cox proportional hazards regression were used to assess hazard ratios for mortality and disease progression (defined as categorical FVC decline ≥10%). The annualized rates of change in functional parameters for each patient were calculated using mixed linear models. Results The study population consisted of 152 IPF patients, of whom 135 (89%) received antifibrotic treatment for IPF during the study follow up. Patients having evidence of 3 or more enlarged mediastinal lymph nodes on baseline CT scan showed increased rates of mortality (HR 5.03, 95% CI 1.86–13.62, p ≤ 0.001) and significant disease progression (HR 2.99, 95% CI 1.22–7.33, p = 0.17) as compared to patients without LNE, after adjusting for GAP stage. Among 62 patients with LNE who underwent a follow up CT scan of the chest and received antifibrotic treatment, 57 (92%) maintained evidence mediastinal LNE over time. Conclusions Diffuse mediastinal lymph node involvement predicts clinically meaningful functional deterioration in patients with IPF.

scholarly journals Mediastinal lymph node enlargement in idiopathic pulmonary fibrosis: relationships with disease progression and pulmonary function trends.

2020 ◽  
Author(s):  
Giacomo Sgalla ◽  
Anna Rita Larici ◽  
Nicoletta Golfi ◽  
Mariarosaria Calvello ◽  
Alessandra Farchione ◽  
...  
Keyword(s):  
Lymph Node ◽  
Idiopathic Pulmonary Fibrosis ◽  
Pulmonary Fibrosis ◽  
Lymph Nodes ◽  
Ct Scan ◽  
Disease Progression ◽  
Mediastinal Lymph Node ◽  
Mediastinal Lymph Nodes ◽  
Lymph Node Enlargement

Abstract Background and objectivesEvidence of mediastinal Lymph Node Enlargement (LNE) on CT scan is a common finding in idiopathic pulmonary fibrosis (IPF). We sought to investigate whether the involvement of mediastinal lymph nodes is associated with accelerated disease progression, and explored the changes occurring in mediastinal lymph nodes during the radiological follow up of these patients.MethodsThis retrospective study included IPF patients referred to a single ILD centre in Italy. A consensus-based assessment of mediastinal LNE on chest CT scan was performed by two thoracic radiologists. Kaplan-Meier curves and multivariate Cox proportional hazards regression were used to assess hazard ratios for mortality and disease progression (defined as categorical FVC decline ≥10%). The annualized rates of change in functional parameters for each patient were calculated using mixed linear models.Results152 IPF patients were included in the analysis, of whom 135 (89%) received antifibrotic treatment for IPF during the study follow up. Patients having evidence of 3 or more enlarged mediastinal lymph nodes on baseline CT scan showed increased rates of mortality (HR 5.03, 95% CI 1.86-13.62, p≤0.001) and significant disease progression (HR 2.99, 95% CI 1.22-7.33, p=0.17) as compared to patients without LNE, after adjusting for GAP stage. Among 62 patients with LNE who underwent a follow up CT scan of the chest and received antifibrotic treatment, 57 (92%) maintained evidence mediastinal LNE over time.ConclusionsDiffuse mediastinal lymph node involvement predicts clinically meaningful functional deterioration in patients with IPF.

scholarly journals A case report: “efficacy of jeevantyadi ghrita netratarpana in diabetic retinopathy”

2018 ◽  
Vol 6 (5th) ◽  
Author(s):  
Hemvati Potdar ◽  
Nutan Radaye
Keyword(s):  
Diabetic Retinopathy ◽  
Potential Role ◽  
Signs And Symptoms ◽  
Effective Measure ◽  
Eye Disorders ◽  
Wide Range ◽  
Treatment Procedures ◽  
Localized Treatment

Background: Diabetic Retinopathy is a condition in which prime involvement is of blood vessels. Netratarpana is localized treatment procedure for inner pathological changes in eye disease, it is a noninvasive and very effective measure compare to other treatment procedures available in other pathies. Therefore effort for the reassessment of Netratarpana has been done to understand the efficacy of Jeevantyadi Ghrita in diabetic retinopathy. Objectives: Detail study of Diabetic Retinopathy. Detail study of Jeevantyadi Ghrita Netratarpan and Raktapittahara medicine Methods: A case study of 48yr/male patient showing signs and symptoms of NPDR who is treated with  Jeevantyadi Ghrita Netratarpana along with oral medication for Diabetes.7 days Netratarpana with a follow up for every 15 days up to 2 months. Result: Patient showed improvement in vision along with concern sign and symptoms. Vision improved from C.F 3 feet to 6/36 in Right Eye and in Left Eye from 6/60 to 6/18. Conclusion:  It is observed that Jeevantyadi Ghrita Netratarpana in the patients of diabetic retinopathy plays a potential role and provides immense information with its therapeutic use in wide range of eye disorders especially in the case of diabetic retinopathy.

scholarly journals Orofacial Granulomatosis Treated with Systemic Steroid: A Case Report

2021 ◽  
Vol 23 (1) ◽  
pp. 80-82
Author(s):  
Prasanna Kumar Jha
Keyword(s):  
Case Report ◽  
Lymph Node ◽  
Systemic Steroid ◽  
Granulomatous Disease ◽  
Histological Evidence ◽  
Orofacial Granulomatosis ◽  
Caseating Granuloma ◽  
Lymph Node Enlargement ◽  
Gingival Enlargement

Orofacial granulomatosis refers to conditions restricted to oral region mainly characterized by chronic swelling of orofacial tissues with histological evidence of non-caseating granuloma. It may be idiopathic where there is absence of identifiable granulomatous disease or may present as a component of localized or generalized Crohn’s disease, tuberculosis and sarcoidosis. The clinical features are facial or lip swelling, angular cheilitis, oral ulcerations, vertical fissures of lips, gingival enlargement, mucosal tags and sometimes lymph node enlargement. A middle-aged female presented to our outpatient department with diffuse chronic swelling of lips which after treatment with systemic steroid showed visible improvement during follow up.

scholarly journals Conventional radiotherapy and intensity-modulated radiotherapy in carcinoma vulva: An experience from a tertiary medical center of India

2019 ◽  
Vol 08 (01) ◽  
pp. 41-43 ◽  
Author(s):  
Koustav Mazumder ◽  
Arun Elangovan ◽  
Bhavana Rai ◽  
Vanita Suri ◽  
Vanita Jain ◽  
...  
Keyword(s):  
Lymph Node ◽  
Lymph Node Dissection ◽  
Inguinal Lymph Node ◽  
Intensity Modulated Radiotherapy ◽  
Disease Free Survival ◽  
Node Dissection ◽  
Inguinal Lymph Node Dissection ◽  
Conventional Radiotherapy ◽  
Free Survival

Abstract Context: Vulvar cancer is one of the uncommon gynecological malignancies. Multimodality treatment with surgery, radiotherapy, and chemotherapy are required for treatment of the disease. Aims: The aim of the study was to evaluate clinical outcome in patients of carcinoma vulva, treated at our institution. Subjects and Methods: This was a retrospective-cohort study done in 50 patients with squamous cell carcinoma of the vulva, treated at our institution from January 2008 to December 2014. Data were analyzed on the basis of age, stage, type of treatment received, and treatment-related toxicity. Disease-free survival and overall survival were estimated. Statistical Analysis Used: Kaplan–Meier survival analysis and Chi-square test were used for statistical analysis. Results: Majority of the patients (52%) had presented with Stage III disease. Thirty-six of 50 patients underwent surgery: simple vulvectomy – 2, radical vulvectomy – 34, bilateral inguinal lymph node dissection was done in 32 patients, and 1 patient underwent ipsilateral-inguinal lymph node dissection. Among 40 patients who received radiotherapy and eight patients received palliative radiotherapy. Seventeen patients underwent intensity-modulated radiotherapy (IMRT) and 15 patients received conventional radiotherapy. Significantly less Grade 2 or more skin toxicity (P = 0.003) observed in patients who underwent IMRT. Among non-IMRT group, eight patients required treatment break during radiation. At a median follow-up time of 25.5 months, median overall survival was 31 months and median disease-free survival was 25 months. About 42% patients were alive and free of disease at last follow-up. Conclusions: Modified radical vulvectomy with inguinal lymph node dissection followed by radiotherapy is the mainstay of management of locally advanced carcinoma vulva. Using IMRT, we could minimize the treatment related radiation toxicity and treatment breaks.

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