Relation Between Serum Copper And Iron With Mercury Pollution In Dentists Used Amalgam Fillings

Background: This study aims to determine and compare the levels of trace elements copper, zinc, selenium and chromium in GCF and serum of patients with periodontitis and healthy individuals. Methods: This cross sectional study includes 24 study subjects recruited from the patients reporting to the Department of Periodontics , Tagore Dental College Chennai. All the selected patients were subjected to a clinical examination done by a single examiner. The estimation of trace elements Copper, Zinc, Selenium and Chromium in GCF and serum is performed using Perkin Elmer optima 5300 Inductively Coupled Plasma Emission Spectrometer (ICPOES). Results: GCF and serum copper levels showed no significant difference in both periodontitis and healthy groups . Selenium levels tend to be the same in both groups. Serum zinc levels are more in periodontitis patients than healthy subjects (p less than 0.01). GCF chromium levels are found to be more in patients with periodontitis than healthy. Conclusions : More research is therefore needed to monitor the role of these trace elements C with an increased sample size to ascertain whether they are associated with a reduced risk of periodontitis.

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SERUM COPPER, MAGNESIUM AND ZINC LEVEL IN WHEEZY INFANTS

Zagazig University Medical Journal ◽

10.21608/zumj.2013.4272 ◽

2013 ◽

Vol 19 (4) ◽

pp. 1-7

Author(s):

Wagdy El-sayed ◽

Eman Aamer

Keyword(s):

Zinc Level ◽

Serum Copper

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CAN REMOTE SENSING MAP MERCURY POLLUTION IN VEGETATED AREAS? THE CASE OF TARKWA, GHANA, AFRICA

10.1130/abs/2018am-323041 ◽

2018 ◽

Author(s):

Jonas Toupal ◽

◽

Nan Crystal Arens

Keyword(s):

Remote Sensing ◽

Mercury Pollution

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Serum Copper Level and Polycystic Ovarian Syndrome: A Meta-Analysis

Gynecologic and Obstetric Investigation ◽

10.1159/000516518 ◽

2021 ◽

pp. 1-8

Author(s):

Qingtao Jiang ◽

Feng Zhang ◽

Lei Han ◽

Baoli Zhu ◽

Xin Liu

Keyword(s):

Large Scale ◽

Polycystic Ovarian Syndrome ◽

Meta Analysis ◽

Serum Copper ◽

Copper Level ◽

Serum Copper Level ◽

Copper Status ◽

Plasma Copper ◽

Mean Differences ◽

Ovarian Syndrome

Introduction: The association of serum copper with polycystic ovarian syndrome (PCOS) has been studied for years, but no definite conclusion is drawn. Therefore, we conducted a meta-analysis to investigate serum copper concentrations in PCOS subjects compared with healthy controls. Methods: Electronic search was performed in PubMed, Google Scholar, and Scopus up to June 30, 2020, without any restriction. Standardized mean differences (SMDs) with corresponding 95% CIs in serum copper levels were employed with random-effects model. I2 was applied to evaluate heterogeneity among studies. Results: Nine studies, measuring plasma copper levels in 1,168 PCOS patients and 1,106 controls, were included. Pooled effect size suggested serum copper level was significantly higher in women with PCOS (SMD = 0.51 μg/mL, 95% CI = [0.30, 0.72], p < 0.0001). The overall heterogeneity was not connected with subgroups of the country, but derived from the opposite result of 1 study. Conclusion: Our research generally indicated circulating copper level in PCOS sufferers was significantly higher than normal controls. Large-scale studies are still needed to elucidate the clear relation between copper status and etiology of PCOS.

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Serum Copper and Zinc Levels and Colorectal Cancer in Adults: Findings from the National Health and Nutrition Examination 2011–2016

Biological Trace Element Research ◽

10.1007/s12011-021-02826-8 ◽

2021 ◽

Author(s):

Chaofeng Zhang ◽

Renqiang Cheng ◽

Jun Ding ◽

Xingjia Li ◽

Hongwen Niu ◽

...

Keyword(s):

Colorectal Cancer ◽

National Health ◽

Serum Copper ◽

Health And Nutrition ◽

Copper And Zinc ◽

Zinc Levels

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Dietary Copper/Zinc Ratio and Type 2 Diabetes Risk in Women: The E3N Cohort Study

Nutrients ◽

10.3390/nu13082502 ◽

2021 ◽

Vol 13 (8) ◽

pp. 2502

Author(s):

Nasser Laouali ◽

Conor-James MacDonald ◽

Sanam Shah ◽

Douae El Fatouhi ◽

Francesca Romana Mancini ◽

...

Keyword(s):

Type 2 Diabetes ◽

Cohort Study ◽

Important Determinant ◽

Epidemiological Data ◽

Serum Copper ◽

Obese Women ◽

Dietary Copper ◽

Zinc Intake ◽

Copper Zinc

The serum copper (Cu) to zinc (Zn) ratio could be an important determinant of Type 2 diabetes (T2D) risk, but prospective epidemiological data are scarce. We aimed to investigate the association between T2D incidence and the dietary Cu/Zn ratio. A total of 70,991 women from the E3N cohort study were followed for 20 years. The intakes of copper and zinc were estimated at baseline using a validated food frequency questionnaire. We identified and validated 3292 incident T2D cases. Spline analysis showed that a Cu/Zn ratio < 0.55 was associated with a lower risk of T2D. Subgroup analyses comparing women in the highest versus the lowest quintile of Cu/Zn ratio showed the same pattern of association for obese women and those with zinc intake ≥8 mg/day. However, for women with zinc intake <8 mg/day, higher Cu/Zn ratio appeared to be associated with higher T2D risk. Our findings suggest that a lower dietary Cu/Zn ratio is associated with a lower T2D risk, especially among obese women and women with zinc intake >8 mg/day. Further studies are warranted to validate our results.

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Biological variation and reference change value data for serum copper, zinc and selenium in Turkish adult population

Turkish Journal of Biochemistry ◽

10.1515/tjb-2020-0298 ◽

2021 ◽

Vol 0 (0) ◽

Author(s):

Ceylan Bal ◽

Serpil Erdogan ◽

Gamze Gök ◽

Cemil Nural ◽

Betül Özbek ◽

...

Keyword(s):

Adult Population ◽

Reference Intervals ◽

Serum Copper ◽

Biological Variation ◽

Serum Samples ◽

Reference Change Value ◽

Index Of Individuality ◽

Copper Zinc ◽

Clinically Significant ◽

Analytical Variation

Abstract Objectives Calculation of biological variation (BV) components is very important in evaluating whether a test result is clinically significant. The aim of this study is to analyze BV components for copper, zinc and selenium in a cohort of healthy Turkish participants. Methods A total of 10 serum samples were collected from each of the 15 healthy individuals (nine female, six male), once a week, during 10 weeks. Copper, zinc and selenium levels were analyzed by atomic absorption spectrometer. BV parameters were calculated with the approach suggested by Fraser. Results Analytical variation (CVA), within-subject BV (CVI), between-subject BV (CVG) values were 8.4, 7.1 and 4.3 for copper; 4.2, 9.1 and 13.7 for zinc; 7.6, 2.5 and 6.9 for selenium, respectively. Reference change values (RCV) were 30.46, 27.56 and 22.16% for copper, zinc and selenium, respectively. The index of individuality (II) values were 1.65, 0.66 and 0.36 for copper, zinc and selenium, respectively. Conclusions According to the results of this study, traditional reference intervals can be used for copper but we do not recommend using it for zinc and selenium. We think that it would be more accurate to use RCV value for zinc and selenium in terms of following significant changes in recurrent results of a patient.

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