Simulation on Temperature Distribution of Effective Lesion Area for Tumor Microwave Ablation Thermotherapy

(1) Background: Microwave ablation (MWA) is a common tumor ablation surgery. Because of the high temperature of the ablation antenna, it is strongly destructive to surrounding vital tissues, resulting in high professional requirements for clinicians. The method used to carry out temperature observation and damage prediction in MWA is significant; (2) Methods: This work employs numerical study to explore temperature distribution of typical tissues in MWA. Firstly, clinical MWA based on isolated biological tissue is implemented. Then, the Pennes models and microwave radiation physics are established based on experimental parameters and existing related research. Initial values and boundary conditions are adjusted to better meet the real clinical materials and experimental conditions. Finally, clinical MWA data test this model. On the premise that the model is matched with clinical MWA, fat and bone are deduced for further heat transfer analysis. (3) Results: Numerical study obtains the temperature distribution of biological tissue in MWA. It observes the heat transfer law of ablation antenna in biological tissue. Additionally, combined with temperature threshold, it generates thermal damage of biological tissues and predicts the possible risks in MWA; (4) Conclusions: This work proposes a numerical study of typical biological tissues. It provides a new theoretical basis for clinically thermal ablation surgery.

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Influences of blood flow parameters on temperature distribution during liver tumor microwave ablation

Frontiers in Bioscience-Landmark ◽

10.52586/4963 ◽

2021 ◽

Vol 26 (9) ◽

pp. 504

Keyword(s):

Blood Flow ◽

Temperature Distribution ◽

Liver Tumor ◽

Microwave Ablation ◽

Flow Parameters

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Thermal Lesion of Renal Tumour as a Function of Catheter Material Property

European Journal of Engineering Research and Science ◽

10.24018/ejers.2018.3.9.886 ◽

2018 ◽

Vol 3 (9) ◽

pp. 12 ◽

Cited By ~ 2

Author(s):

Olumide Adewole Towoju ◽

Moses Omolayo Petinrin

Keyword(s):

Temperature Distribution ◽

Material Property ◽

Relative Permittivity ◽

Microwave Ablation ◽

Comsol Multiphysics ◽

Type B ◽

Thermal Lesion ◽

Time Of Application ◽

Teflon Af ◽

Time Period

The extent of lesion achieved during microwave ablation is dependent on some factors which include the time period of application, its intensity, antenna geometry, and relative permittivity of the tissue. Several studies have been conducted on microwave ablation for the treatment of tumours and have focused on different antenna geometries, its intensity, and time of application. This work seeks to find a correlation between the relative permittivity of the catheter and the temperature distribution which determines necrosis of the tissue by using Tefzel ETFE, Teflon FEP, PFA Teflon type A, PFA Teflon type B, Teflon AF, and PTFE Teflon type B while modelling using COMSOL Multiphysics. The extent of the thermal lesion was observed to be dependent on the relative permittivity of the catheter material, with Tefzel ETFE giving the best performance and Teflon AF providing the least.

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Numerical Analysis of Human Cancer Therapy Using Microwave Ablation

Applied Sciences ◽

10.3390/app10010211 ◽

2019 ◽

Vol 10 (1) ◽

pp. 211 ◽

Cited By ~ 1

Author(s):

Marwa Selmi ◽

Abdul Aziz Bin Dukhyil ◽

Hafedh Belmabrouk

Keyword(s):

Temperature Distribution ◽

Cancer Cells ◽

Tumor Cells ◽

Microwave Power ◽

Microwave Ablation ◽

Human Cancer ◽

Surrounding Tissue ◽

Hyperthermia Treatment ◽

Distribution Profile ◽

Wave Effects

Microwave ablation is one type of hyperthermia treatment of cancer that involves heating tumor cells. This technique uses electromagnetic wave effects to kill cancer cells. A micro-coaxial antenna is introduced into the biological tissue. The radiation emitted by the antenna is absorbed by the tissue and leads to the heating of cancer cells. The diffuse increase in temperature should reach a certain value to achieve the treatment of cancer cells but it should be less than a certain other value to avoid damaging normal cells. This is why hyperthermia treatment should be carefully monitored. A numerical simulation is useful and may provide valuable information. The bio-heat equation and Maxwell’s equations are solved using the finite element method. Electro-thermal effects, temperature distribution profile, specific absorption rate (SAR), and fraction of necrotic tissue within cancer cells are analyzed. The results show that SAR and temperature distribution are strongly affected by input microwave power. High microwave power causes a high SAR value and raises the temperature above 50 °C, which may destroy healthy cells. It is revealed that with a power of 10 W, the tumor cells will be killed without damaging the surrounding tissue.

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