scholarly journals Fluoro-siloxanyl Styrene Rigid Gas Permeable Contact Lens Fabric characteristics and outcomes with extended use on animal model cornea

2019 ◽  
Vol 70 (11) ◽  
pp. 4003-4006

In this paper, we report the relation between fabric characteristics and animal model cornea modifications associated with extended use of fluoro-siloxanyl styrene rigid gas permeable contact lens. Siloxanyl styrene and fluoromethacrylate rigid gas permeable contact lens is a newly designed optical medical device used in orthokeratology with an FDA approval of continuous wear for up to 30 days. To assess the influence on the cornea an animal model was used and histological data were collected. Scanning electron microscopy (SEM) was performed on the used lenses. Our conclusions concedes that with respects of the material, doctor’s slit lamp lens observation on regular basis should be considered as surface debris and lens scratches can influence the cornea in extended wear. Keywords: siloxanyl styrene and fluoromethacrylate, rigid gas permeable contact lens, surface debris, extended

2019 ◽  
Vol 70 (11) ◽  
pp. 4003-4006
Author(s):  
Costin Alexandru Leasu Branet ◽  
Sinziana Istrate ◽  
Liliana Mary Voinea ◽  
Eniko Volceanov ◽  
Radu Ciuluvica ◽  
...  

In this paper, we report the relation between fabric characteristics and animal model cornea modifications associated with extended use of fluoro-siloxanyl styrene rigid gas permeable contact lens. Siloxanyl styrene and fluoromethacrylate rigid gas permeable contact lens is a newly designed optical medical device used in orthokeratology with an FDA approval of continuous wear for up to 30 days. To assess the influence on the cornea an animal model was used and histological data were collected. Scanning electron microscopy (SEM) was performed on the used lenses. Our conclusions concedes that with respects of the material, doctor�s slit lamp lens observation on regular basis should be considered as surface debris and lens scratches can influence the cornea in extended wear.


2002 ◽  
Vol 127 (1) ◽  
pp. 67-72 ◽  
Author(s):  
Riccardo D'Eredità ◽  
Roger R. Marsh ◽  
Silvano Lora ◽  
Ken Kazahaya

OBJECTIVE: We investigated pressure-equalizing (PE) tubes made of biodegradable, absorbable material in an animal model. METHODS: PE tubes, made of poly-bis(ethylanate)phosphazene (PBE) were inserted in 55 ears of 28 Hartley guinea pigs, with survival times of 10, 30, and 60 days after tube insertion. In vivo reactions between the PBE-PE tube and the tympanic membrane (TM) were studied. Tubes, TMs, and middle ears were examined by scanning electron microscopy and light microscopy. RESULTS: There was neither infection nor an inflammatory reaction to the tube within the middle ear in any animal. At 30 days, 53% of the tubes had disintegrated. At 60 days, tubes were still functioning in the 25% of ears. CONCLUSION: More research must be performed before these new PBE PE tubes can be considered for clinical use. Nonetheless, these tubes are promising. The disintegration rate can be controlled by varying the formulation of the polymer, so treatment can be adjusted to the needs of each patient.


2006 ◽  
Vol 309-311 ◽  
pp. 783-788 ◽  
Author(s):  
E.T. Uzumaki ◽  
C.S. Lambert ◽  
N.A. Batista ◽  
W.D. Belangero ◽  
Cecília A.C. Zavaglia

Diamond-like carbon (DLC) coatings were deposited on titanium alloy (Ti-13Nb-13Zr) by plasma immersion process. DLC-coated Ti alloy and uncoated Ti were investigated in an animal model using the femoral condyles of rats for intervals of 4 and 12 weeks postoperatively. The interface between the implants and bones of the femoral condyles were analysed using scanning electron microscopy (SEM) by backscattering. The results showed that the DLC coatings were well tolerated in both periods.


Cornea ◽  
2010 ◽  
Vol 29 (7) ◽  
pp. 732-736 ◽  
Author(s):  
Raimondo Forte ◽  
Gilda Cennamo ◽  
Salvatore Del Prete ◽  
Ida Cesarano ◽  
Antonio Del Prete

2011 ◽  
Vol 64 (2) ◽  
pp. 159-162
Author(s):  
Armando Pérez de Prado ◽  
Claudia Pérez-Martínez ◽  
Carlos Cuellas-Ramón ◽  
José M. Gonzalo-Orden ◽  
Marta Regueiro-Purriños ◽  
...  

Author(s):  
P.S. Porter ◽  
T. Aoyagi ◽  
R. Matta

Using standard techniques of scanning electron microscopy (SEM), over 1000 human hair defects have been studied. In several of the defects, the pathogenesis of the abnormality has been clarified using these techniques. It is the purpose of this paper to present several distinct morphologic abnormalities of hair and to discuss their pathogenesis as elucidated through techniques of scanning electron microscopy.


Author(s):  
P.J. Dailey

The structure of insect salivary glands has been extensively investigated during the past decade; however, none have attempted scanning electron microscopy (SEM) in ultrastructural examinations of these secretory organs. This study correlates fine structure by means of SEM cryofractography with that of thin-sectioned epoxy embedded material observed by means of transmission electron microscopy (TEM).Salivary glands of Gromphadorhina portentosa were excised and immediately submerged in cold (4°C) paraformaldehyde-glutaraldehyde fixative1 for 2 hr, washed and post-fixed in 1 per cent 0s04 in phosphosphate buffer (4°C for 2 hr). After ethanolic dehydration half of the samples were embedded in Epon 812 for TEM and half cryofractured and subsequently critical point dried for SEM. Dried specimens were mounted on aluminum stubs and coated with approximately 150 Å of gold in a cold sputtering apparatus.Figure 1 shows a cryofractured plane through a salivary acinus revealing topographical relief of secretory vesicles.


Author(s):  
Nakazo Watari ◽  
Yasuaki Hotta ◽  
Yoshio Mabuchi

It is very useful if we can observe the identical cell elements within the same sections by light microscopy (LM), transmission electron microscopy (TEM) and/or scanning electron microscopy (SEM) sequentially, because, the cell fine structure can not be indicated by LM, while the color is; on the other hand, the cell fine structure can be very easily observed by EM, although its color properties may not. However, there is one problem in that LM requires thick sections of over 1 μm, while EM needs very thin sections of under 100 nm. Recently, we have developed a new method to observe the same cell elements within the same plastic sections using both light and transmission (conventional or high-voltage) electron microscopes.In this paper, we have developed two new observation methods for the identical cell elements within the same sections, both plastic-embedded and paraffin-embedded, using light microscopy, transmission electron microscopy and/or scanning electron microscopy (Fig. 1).


Sign in / Sign up

Export Citation Format

Share Document