Tissue Response in the Femur of Rats After Implantation of Diamond-Like Carbon Coatings on Ti-13Nb-13Zr Produced by Plasma Immersion

2006 ◽  
Vol 309-311 ◽  
pp. 783-788 ◽  
Author(s):  
E.T. Uzumaki ◽  
C.S. Lambert ◽  
N.A. Batista ◽  
W.D. Belangero ◽  
Cecília A.C. Zavaglia

Diamond-like carbon (DLC) coatings were deposited on titanium alloy (Ti-13Nb-13Zr) by plasma immersion process. DLC-coated Ti alloy and uncoated Ti were investigated in an animal model using the femoral condyles of rats for intervals of 4 and 12 weeks postoperatively. The interface between the implants and bones of the femoral condyles were analysed using scanning electron microscopy (SEM) by backscattering. The results showed that the DLC coatings were well tolerated in both periods.

2019 ◽  
Vol 70 (11) ◽  
pp. 4003-4006

In this paper, we report the relation between fabric characteristics and animal model cornea modifications associated with extended use of fluoro-siloxanyl styrene rigid gas permeable contact lens. Siloxanyl styrene and fluoromethacrylate rigid gas permeable contact lens is a newly designed optical medical device used in orthokeratology with an FDA approval of continuous wear for up to 30 days. To assess the influence on the cornea an animal model was used and histological data were collected. Scanning electron microscopy (SEM) was performed on the used lenses. Our conclusions concedes that with respects of the material, doctor’s slit lamp lens observation on regular basis should be considered as surface debris and lens scratches can influence the cornea in extended wear. Keywords: siloxanyl styrene and fluoromethacrylate, rigid gas permeable contact lens, surface debris, extended


2002 ◽  
Vol 127 (1) ◽  
pp. 67-72 ◽  
Author(s):  
Riccardo D'Eredità ◽  
Roger R. Marsh ◽  
Silvano Lora ◽  
Ken Kazahaya

OBJECTIVE: We investigated pressure-equalizing (PE) tubes made of biodegradable, absorbable material in an animal model. METHODS: PE tubes, made of poly-bis(ethylanate)phosphazene (PBE) were inserted in 55 ears of 28 Hartley guinea pigs, with survival times of 10, 30, and 60 days after tube insertion. In vivo reactions between the PBE-PE tube and the tympanic membrane (TM) were studied. Tubes, TMs, and middle ears were examined by scanning electron microscopy and light microscopy. RESULTS: There was neither infection nor an inflammatory reaction to the tube within the middle ear in any animal. At 30 days, 53% of the tubes had disintegrated. At 60 days, tubes were still functioning in the 25% of ears. CONCLUSION: More research must be performed before these new PBE PE tubes can be considered for clinical use. Nonetheless, these tubes are promising. The disintegration rate can be controlled by varying the formulation of the polymer, so treatment can be adjusted to the needs of each patient.


2015 ◽  
Vol 723 ◽  
pp. 502-506
Author(s):  
Yu Luo ◽  
Qing Yun Chen ◽  
Huan Yuan ◽  
Ming Xu ◽  
Shu Long Huang

The effects of nano-diamond seeds on the performance of diamond-like carbon (DLC) films were investigated. In this study, the high uniform DLC films were deposited on substrates seeded with nano-diamond by using a magnetron sputtering system. Then, the effects of nano-diamond seeds on DLC films were determined. Raman spectroscopy revealed a decrease of sp3 fraction due to the introduction of nano-diamond seeds. Atomic force microscope (AFM) observed all samples have an average root mean square (RMS) roughness of 1.8 nm. Scanning electron microscopy (SEM) displayed that a large number of small size conical hillock geometrical anomalies can be caused by nano-diamond seeds. Indentation tests revealed that nano-diamond seeds can enhance the hardness of DLC films, whose hardness range is from 28.3 GPa to 32.1 GPa in this work.


2019 ◽  
Vol 70 (11) ◽  
pp. 4003-4006
Author(s):  
Costin Alexandru Leasu Branet ◽  
Sinziana Istrate ◽  
Liliana Mary Voinea ◽  
Eniko Volceanov ◽  
Radu Ciuluvica ◽  
...  

In this paper, we report the relation between fabric characteristics and animal model cornea modifications associated with extended use of fluoro-siloxanyl styrene rigid gas permeable contact lens. Siloxanyl styrene and fluoromethacrylate rigid gas permeable contact lens is a newly designed optical medical device used in orthokeratology with an FDA approval of continuous wear for up to 30 days. To assess the influence on the cornea an animal model was used and histological data were collected. Scanning electron microscopy (SEM) was performed on the used lenses. Our conclusions concedes that with respects of the material, doctor�s slit lamp lens observation on regular basis should be considered as surface debris and lens scratches can influence the cornea in extended wear.


Author(s):  
R.J. Narconis ◽  
J.W. Spindler ◽  
L.J. Billy ◽  
S. Rana

Tissue response to three types of vascular prosthetic materials was evaluated by correlation of scanning electron microscopy and light microscopy. Two clinically established materials, woven dacron and woven teflon, and an experimental material, expanded polytetrafluoroethylene (Goretex) were employed. They were implanted in the subcutaneous tissue of rats and removed at time intervals ranging from 48 hours to 30 days. Half of the retrieved material was fixed in 10% formalin and examined by routine light microscopy. The other half was glutaraldehyde fixed and acetone/CO2 critical point dried, then examined by scanning electron microscopy.Prior to this study, the three materials were evaluated by scanning electron microscopy to establish topographic landmarks. The woven dacron had bundles of relatively large, rough fibers; the woven teflon had fibers of similar size but with a smooth surface; the PTFE, however, had a surface composed of fibers and pores only a few micra in diameter.


2020 ◽  
Vol 985 ◽  
pp. 69-73
Author(s):  
Satoshi Okano ◽  
Masayuki Mori ◽  
Sengo Kobayashi ◽  
Takeaki Okamoto

Surface morphology and composition of anodized Ti-15Zr-4Nb-4Ta alloys with nanotube were examined by using X-ray diffractometry and analytical scanning electron microscopy. The Ti alloy consisted of α and β phases. Anodizing to form nanotube on the Ti alloy was carried out using electrolyte of 0.2 wt.% NH4F and 2 Vol.% H2O in ethylene glycol under different potential at from 30 to 60V. SEM observation showed that nanotubes were vertically aligned on surface of the Ti alloy. Inner diameter of these nanotubes varied from 45 to 127 nm with increasing applied potential to the specimen from 30 to 60 V. Surface of the Ti alloy with nanotube was ragged due to the difference in dissolution rate of the internal structure of α and β phases.


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