Effects of γ-Irradiated Pork Diet on Cytochrome P-450 System, Microsome Glucose 6-Phosphatase Activity and Antioxidative Defense Systems in Rat Hepatocarcinogenesis

2003 ◽  
Vol 8 (2) ◽  
pp. 158-161
Author(s):  
Il-Jun Kang ◽  
Jung-Hee Kim ◽  
Cha-Kwon Chung
2019 ◽  
Vol 97 (6) ◽  
pp. 740-749
Author(s):  
Tantip Boonsong ◽  
Siriporn Pakwan ◽  
Wanida Chawnawa

The aim of this study was to investigate the effects of extracts from germinated (GPE) and non-germinated peanuts (NGPE) on adipogenesis and oxidative status in normal and oxidative-stress-induced 3T3-L1 mouse adipocytes. The treated cells were analysed for cell growth, lipid accumulation, levels of intracellular reactive oxygen species (ROS), and the expression levels of mRNAs and proteins related to adipogenesis and antioxidative defense systems. The results indicated that an extract from peanuts made 9 days after germination (9GPE) reduced lipid contents and mRNA expression of adipogenesis-related genes to a greater extent than an extract from peanuts made 1-day after germination (1GPE) or from NGPE, respectively. In oxidative-stress-induced adipocytes, 9GPE decreased ROS levels, lipid content, and the protein expression of peroxisome-proliferator-activated receptor gamma, and also increased the protein expression of antioxidants. These results illustrate the anti-adipogenic capacity and oxidative status improvement achievable with GPE, and that it could be used as a putative therapeutic agent in the prevention of and (or) treatment of obesity and diseases associated with oxidative stress.


1991 ◽  
Vol 10 (1-4) ◽  
pp. 187-189
Author(s):  
Rongliang Zheng ◽  
Zhentu Yang

1985 ◽  
Vol 49 (10) ◽  
pp. 3085-3087 ◽  
Author(s):  
Toshihiko OSAWA ◽  
Ramarathnam NARASIMHAN ◽  
Shunro KAWAKISHI ◽  
Mitsuo NAMIKI ◽  
Toru TASHIRO

1981 ◽  
Vol 196 (2) ◽  
pp. 585-589 ◽  
Author(s):  
M B Cooper ◽  
M R Estall ◽  
B R Rabin

1. The phospholipid bilayer of intact vesicles from smooth endoplasmic reticulum is impermeable to macromolecules. Specific and non-specific proteinases were used to investigate the site of membrane proteins in the transverse plane of the bilayer. 2. When two proteinases were used in conjunction, denaturing effects additional to proteolysis were observed on cytochrome P-450 content and glucose 6-phosphatase activity which did not depend on the integrity of the phospholipid bilayer. 3. When lipid peroxidation was inhibited, these effects were not observed.


2012 ◽  
Vol 169 (17) ◽  
pp. 1680-1689 ◽  
Author(s):  
Fang-Li Luo ◽  
Björn Thiele ◽  
Ingar Janzik ◽  
Bo Zeng ◽  
Ulrich Schurr ◽  
...  

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