PREDICTIVE FACTORS IN THE CHOICE OF SURGICAL TREATMENT FOR COLORECTAL CANCER WITH LAPAROSCOPIC OR "OPEN" ACCESS

2017 ◽  
Vol 63 (3) ◽  
pp. 470-474
Author(s):  
Rustem Topuzov ◽  
Georgiy Manikhas ◽  
Eskender Topuzov ◽  
Mikhail Khanevich ◽  
Magomed Abdulaev ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Surgical Treatment ◽  
Postoperative Complications ◽  
Open Access ◽  
Comparative Study ◽  
Retrospective Analysis ◽  
Predictive Factors

There are presented results of surgical treatment of 347 patients with colorectal cancer. Based on the retrospective analysis a comparative study of results of surgical treatment for colorectal cancer using laparoscopic technologies and “open” access was carried out. Predictive factors that correlate with the risk of postoperative complications with laparoscopic and “open” access at the surgical stage of treatment for colorectal cancer were determined.

Outcomes of Surgical and Nonsurgical Treatment for Colorectal Cancer in Nonagenarian Patients

2021 ◽  
pp. 000313482199506
Author(s):  
Youngbae Jeon ◽  
Kyoung-Won Han ◽  
Won-Suk Lee ◽  
Jeong-Heum Baek
Keyword(s):  
Colorectal Cancer ◽  
Overall Survival ◽  
Surgical Treatment ◽  
Postoperative Complications ◽  
Postoperative Mortality ◽  
Nonsurgical Treatment ◽  
Perioperative Outcomes ◽  
Rank Test ◽  
Kaplan Meier ◽  
Number Of Patients

Purpose This study is aimed to evaluate the clinical outcomes of surgical treatment for nonagenarian patients with colorectal cancer. Methods This retrospective single-center study included patients diagnosed with colorectal cancer at the age of ≥90 years between 2004 and 2018. Patient demographics were compared between the operation and nonoperation groups (NOG). Perioperative outcomes, histopathological outcomes, and postoperative complications were evaluated. Overall survival was analyzed using Kaplan-Meier methods and log-rank test. Results A total of 31 patients were included (16 men and 15 women), and the median age was 91 (range: 90‐96) years. The number of patients who underwent surgery and who received nonoperative management was 20 and 11, respectively. No statistical differences in baseline demographics were observed between both groups. None of these patients were treated with perioperative chemotherapy or radiotherapy. Surgery comprised 18 (90.0%) colectomies and 2 (10.0%) transanal excisions. Short-term (≤30 days) and long-term (31‐90 days) postoperative complications occurred in 7 (35.0%) and 4 (20.0%) patients, respectively. No complications needed reoperation, such as anastomosis leakage or bleeding. No postoperative mortality occurred within 30 days: 90-day postoperative mortality occurred in two patients (10.0%), respectively. The median overall survival of the operation group was 31.6 (95% confidence interval: 26.7‐36.5) and that of NOG was 12.5 months (95% CI: 2.4‐22.6) ( P = 0.012). Conclusion Surgical treatment can be considered in carefully selected nonagenarian patients with colorectal cancer in terms of acceptable postoperative morbidity, with better overall survival than the nonsurgical treatment.

scholarly journals Long-Term Survival in Octogenarians After Surgical Treatment for Colorectal Cancer: Prevention of Postoperative Complications is Key

2018 ◽  
Vol 25 (13) ◽  
pp. 3874-3882 ◽  
Author(s):  
Linda B. M. Weerink ◽  
Christina M. Gant ◽  
Barbara L. van Leeuwen ◽  
Geertruida H. de Bock ◽  
Ewout A. Kouwenhoven ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Surgical Treatment ◽  
Postoperative Complications ◽  
Cancer Prevention ◽  
Term Survival ◽  
Long Term Survival ◽  
Colorectal Cancer Prevention

Surgical management of synchronous colorectal liver metastases: Simultaneous versus staged resections.

2014 ◽  
Vol 32 (3_suppl) ◽  
pp. 616-616
Author(s):  
Igor Shchepotin ◽  
Andrii Lukashenko ◽  
Olena Kolesnik ◽  
Anton Burlaka
Keyword(s):  
Colorectal Cancer ◽  
Surgical Treatment ◽  
Postoperative Complications ◽  
Liver Metastases ◽  
Metastatic Cancer ◽  
Economic Effect ◽  
Hepatic Metastases ◽  
Group A ◽  
Bed Days ◽  
Group B

616 Background: Surgical treatment of metastatic colorectal cancer remains the only method that improves overall 5-year survival. This study aimed to compare the surgical outcome and survival benefit between synchronous and staged resection of liver metastases from colorectal cancer. Methods: Clinicopathologic data, treatments, and postoperative outcomes from 110 patients who underwent simultaneous (48 patients, group A) or staged (62 patients, group B) colorectal and hepatic resections at clinic of National cancer institute in period of 2008-2013 were reviewed. Results: Postoperative complications in patients with simultaneous resections (group A) were observed in 13 cases (27.1%), including 5, 1, 4, 2, 0, and 1 of grades I, II, IIIa, IIIb, IV, and V, respectively. Similar results have been reported in group B after staged resections, where overall postoperative complications registered in 16 patients (25.8 %), including 4, 3, 6, 3, 0 of grades I, II, IIIa, IIIb, and IV respectively. Overall level of post-operative complications in the groups A and B after surgical stages finishing did not differ statistically (p=0.96). Shorter operative intervention duration was registered in the group A – (311±10.1) min, whereas in the group B it was (496.6±16.2) min (р<0.001). Patients after staged resection stayed in clinic for a longer time – 23.9±0.8 bed-days, when simultaneous resections provided with shorter recovery terms in post-operative period – 9.8±0.5 bed-days (p<0.001). Overall 3-year survival in the group of patients with simultaneous resections (group А) was 42 % and in the group B 55 % (р=0.22). Conclusions: Analysis of our research indicated necessity of the development of differentiated approach in management of synchronous colorectal liver metastatic cancer. Simultaneous resections of colorectal cancer primary lesions and hepatic metastases were safe and could serve as a primary option for selected patients. Subsequent research should be directed towards study of prognosis factors and criteria for patients’ selection for surgical treatment groups, assessment of economic effect, and patients life quality.

Assessment of postoperative complications of transurethral contact pyelocalycоlithotripsy in patients with high-density stones according to the Clavien – Dindo classification

2020 ◽  
Vol 10 (4) ◽  
pp. 309-316
Author(s):  
Toirkhon Kh. Nazarov ◽  
Anisjon I. Tursunov ◽  
Ivan V. Rychkov ◽  
Magomed A. Ahmedov ◽  
Kseniya E. Trubnikova ◽  
...  
Keyword(s):  
Surgical Treatment ◽  
Postoperative Complications ◽  
Retrospective Analysis ◽  
Kidney Stones ◽  
Postoperative Period ◽  
Topical Issue ◽  
Unified Algorithm ◽  
Cavity System ◽  
Treatment Of Urolithiasis

Improving the effectiveness of treatment of urolithiasis is a topical issue in modern urology. Despite a large number of studies on this problem, there is currently no unified algorithm for assessing postoperative complications of removal of calculi of the renal cavity system by transurethral access. Purpose of the study: based on a retrospective analysis to adapt the classification of postoperative complications according to Clavien Dind from 2004 to describe the complications of transurethral contact pyelocalicolithotripsy. Materials and methods. A retrospective analysis of the results of surgical treatment of 211 patients with kidney stones with a density of 960 HU to 1840 HU was performed. Ultrasonic energy was used for lithotripsy. Criteria for the normal course of the postoperative period in patients have been formulated. Results. The number of postoperative complications was calculated. The obtained data are distributed according to the corresponding gradations of the adapted Clavien Dindо classification. Conclusion. The improved Clavien Dindo classification, taking into account the adaptation, can be used as an up-to-date, accessible and logical template for assessing the postoperative complications of transurethral contact pyelocalicolithotripsy.

scholarly journals Colorectal cancer metastases to the lungs: outcomes of surgical treatment and prognostic factors

2020 ◽  
Vol 10 (2) ◽  
pp. 33-41
Author(s):  
B. B. Akhmedov ◽  
P. V. Kononets ◽  
M. Yu. Fedyanin ◽  
Z. Z. Mamedli ◽  
S. S. Gordeev ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Overall Survival ◽  
Surgical Treatment ◽  
Survival Rate ◽  
Postoperative Complications ◽  
Progression Free Survival ◽  
Free Survival ◽  
Cancer Metastases ◽  
Colorectal Cancer Metastases

Objective: to evaluate short-term and long-term outcomes of surgical treatment for colorectal cancer metastases to the lungs and to analyze factors affecting the efficacy of surgery. Materials and methods. This study included 211 patients with colorectal cancer metastases to the lungs treated between 1994 and 2014. We enrolled patients with resectable or conventionally resectable metastases (according to chest computed tomography evaluated by a thoracic surgeon); the exclusion criteria were as follows: multiple primary tumors and age more than 85 years. We assessed the type of surgeries, frequency of R0 resections, incidence of postoperative complications, overall survival, and progression-free survival. Results. One hundred and sixty-two patients out of 211 (76.8 %) have undergone atypical lung resection. Forty-nine patients (23.2 %) have undergone pneumonectomy, bilobectomy, or lobectomy. The majority of patients (96.2 %) have had R0 resection, whereas 2.9 % of study participants have had R1 or R2 resections. One patient has undergone a trial surgery. Clinically significant postoperative complications were observed in 4 (2 %) patients; postoperative mortality was 0.5 % (1 case). The five-year overall survival rate was 52.7 %; the 5-year progression-free survival rate was 45.8 %. Development of metastases within 24 months after primary surgery was found to be a significant factor negatively affecting overall survival (hazard ratio 0.347; 95 % confidence interval 0.227–0.53; р <0.0001). Conclusions. Surgical treatment is currently the only truly effective treatment, which can improve long-term survival of patients with colorectal cancer metastases to the lungs; the best treatment results are achieved in patients with a relapse-free interval of more than 24 months. 

scholarly journals Milligan–Morgan hemoroidektomijos: Vilniaus universiteto ligoninės "Santariškių klinikos" Centro filialo patirtis

2004 ◽  
Vol 2 (4) ◽  
pp. 0-0
Author(s):  
Žymantas Jagelavičius ◽  
Narimantas Evaldas Samalavičius ◽  
Tomas Poškus ◽  
Liudvikas Kervys ◽  
Romanas Kęstutis Drąsutis
Keyword(s):  
Surgical Treatment ◽  
Postoperative Complications ◽  
General Anesthesia ◽  
Retrospective Analysis ◽  
Faecal Incontinence ◽  
Early Recurrence ◽  
Long Term Results ◽  
Anal Region ◽  
Age And Sex

Žymantas Jagelavičius, Narimantas Evaldas Samalavičius, Tomas Poškus, Liudvikas Kervys, Romanas Kęstutis DrąsutisKoloproktologijos poskyris, Pilvo chirurgijos III skyrius,Vilniaus universiteto ligoninės "Santariškių klinikos"Centro filialas, Žygimantų g. 3, LT-01102 VilniusEl. paštas: [email protected] Tikslas Retrospektyviai išnagrinėti Milligan–Morgan hemoroidektomijų patirtį, įvertinti vėlyvuosius rezultatus. Ligoniai ir metodai Išnagrinėtos 270 ligonių, 1985–1999 m. VUL „Santariškių klinikos“ Centro filiale operuotų nuo hemorojaus, ligos istorijos. Iš jų 252 operuoti Milligan–Morgan metodu. Registruotas ligonių amžius, lytis, ligos trukmė iki operacijos, hospitalizavimo trukmė, hemorojaus laipsnis. Antro laipsnio hemorojumi sirgo 20 (7,9%), trečio – 185 (73,4%), ketvirto – 47 (18,7%) ligoniai. Bendrinė nejautra taikyta 144 (57,1%), spinalinė – 64 (25,4%), vietinė – 44 (17,5%) ligoniams. Siekiant įvertinti vėlyvuosius rezultatus, nuo 2001 m. spalio iki 2002 m. spalio visi ligoniai buvo apklausti paštu ar telefonu pagal iš anksto paruoštą klausimyną. Į klausimus atsakė 150 (59,5%) ligonių. Rezultatai Iš 252 ligonių pooperacinė eiga komplikavosi 16 (6,3%) ligonių: devyniems (3,6%) – šlapinimosi sutrikimu, septyniems (2,8%) – kraujavimu; trys ligoniai operuoti dar kartą. Išangės sritis sugijo per 2–16, vidutiniškai per 4,6 savaites. Iš 150 apklaustųjų pakartotinai nuo recidyvo operuoti trys (2,0%) ligoniai. Jie operacinį gydymą įvertino: labai gerai – 69 (46,0%), gerai 68 – (45,3%), patenkinamai – 12 (8,0%), blogai – vienas (0,7%) ligonis. Sutrikusia išangės raukų funkcija skundėsi 25 (16,7%) ligoniai, ją vertinome pagal Klivlendo išmatų nelaikymo klasifikaciją: 1 balas – vienas (0,7%) ligonis, 2 balai – trys (2%), 3 balai – šeši (4%), 4 balai – šeši (4%), 5 balai – nebuvo, 6 balai – trys (2,0%), 7 balai – nebuvo, 8 balai – du (1,3%), 9 balai – nebuvo, 10 balų – vienas (0,7%). Išvados Hemoroidektomija Milligan–Morgan būdu yra saugi ir veiksminga. Dauguma ligonių chirurginiu gydymu buvo patenkinti. Tačiau nereikia pamiršti, kad ir nedidelei daliai ligonių gali sutrikti išangės raukų funkcija. Reikšminiai žodžiai: hemorojus, Milligan–Morgan hemoroidektomija, rezultatai, išmatų nelaikymas Milligan–Morgan hemorrhoidectomies: experience of the Center Branch of Vilnius Univerity "Santariškių klinikos" Hospital Žymantas Jagelavičius, Narimantas Evaldas Samalavičius, Tomas Poškus, Liudvikas Kervys, Romanas Kęstutis Drąsutis Objective Retrospective analysis of the experience and long-term results after Milligan–Morgan hemorrhoidectomy. Patients and methods During the period 1985–1999, 270 patients underwent hemorrhoidectomy in our hospital, of them 252 by using the Milligan–Morgan technique. We registered the age and sex of patients, time of illness and of hospitalization, degree of hemorrhoids: 20 (7.9%) had II°, 185 (73.4%) – III°, 47 (18.7%) – IV°. General anesthesia was used in 144 (57.1%), regional (spinal or epidural) in 64 (25.4%), local in 44 (17.5%) patients. To evaluate long-term results, all patients were interviewed by telephone or mail under a special questionnaire; 150 (59,5%) patients replied. Results Of 252 patients, 16 (6.3%) developed postoperative complications: nine (3.6%) troubles of urination, six (2.4%) bleeding, one (0.4%) early recurrence; three patients were reoperated on. The anal region healed over 2–16 (average 4.6) weeks. Three patients (2.0%) of the 150 interviewed were operated on repeatedly because of recurrence. They evaluated our surgical treatment: very good 69 (46.0%), good 68 (45.3%), satisfactory 12 (8.0%), bad one (0.7%) patient. Faecal incontinence was mentioned by 25 (16.7%) patients. We ranked it using Cleveland’s feacal incontinence classification: 1 point – one (0.7%) patient, 2b. – three (2%), 3b. – six (4%), 4b. – six (4%), 5b. – zero, 6b. – three (2.0%), 7b. – zero, 8b. – two (1.3%), 9b. – zero, 10b. – one (0.7%) patient. Conclusions Milligan–Morgan hemorrhoidectomy in our experience is a rather safe and effective method of treatment of hemorrhoides. The majority of the patients were satisfied with our treatment. However, we should have in mind that for a small part of patients mild faecal incontinence is possible. Keywords: hemorrhoids, Milligan–Morgan hemorrhoidectomy, results, incontinece

Hypertension and beta-blocker use as prognostic and predictive factors in metastatic colorectal cancer: A retrospective analysis of NCIC CTG CO.17.

2016 ◽  
Vol 34 (15_suppl) ◽  
pp. e15025-e15025
Author(s):  
Shelly Sud ◽  
Christopher J. O'Callaghan ◽  
Christos Stelios Karapetis ◽  
Caleb Jonker ◽  
Timothy Jay Price ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Metastatic Colorectal Cancer ◽  
Retrospective Analysis ◽  
Predictive Factors ◽  
Beta Blocker ◽  
Prognostic And Predictive Factors

scholarly journals POSTOPERATIVE INTRAABDOMINAL COMPLICATIONS IN COLON CANCER SURGERY COMPLICATED BY BOWEL OBSTRUCTION AND PERFORATION OF THE TUMOR

2015 ◽  
Vol 174 (5) ◽  
pp. 98-104 ◽  
Author(s):  
S. A. Aliev ◽  
E. S. Aliev ◽  
B. M. Zeinalov
Keyword(s):  
Colon Cancer ◽  
Surgical Treatment ◽  
Postoperative Complications ◽  
Retrospective Analysis ◽  
Large Intestine ◽  
Bowel Obstruction ◽  
Abdominal Cavity ◽  
Cancer Surgery ◽  
Perioperative Prophylaxis ◽  
Colon Cancer Surgery

The article presents a retrospective analysis of the results of surgical treatment of postoperative intraabdominal complications in 42 patients with colon cancer complicated by bowel obstruction and perforation of the tumor. The pyoinflammatory processes such as peritonitis and abscesses of abdominal cavity took a leading place in the structure of postoperative complications according to the authors. Method of «closed» decompression and intraluminal irrigation of the large intestine without wide opening of organ lumen was developed and applied into practice as perioperative prophylaxis of pyoinflammatory processes. These measures allowed reducing the rate of postoperative intraabdominal complications from 19,2 to 7,7%.

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