scholarly journals A new member of the fusaricidin family – structure elucidation and synthesis of fusaricidin E

2017 ◽  
Vol 13 ◽  
pp. 1430-1438 ◽  
Author(s):  
Marcel Reimann ◽  
Louis P Sandjo ◽  
Luis Antelo ◽  
Eckhard Thines ◽  
Isabella Siepe ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Nmr Spectroscopy ◽  
Tandem Mass Spectrometry ◽  
Family Structure ◽  
Structure Elucidation ◽  
Side Chain ◽  
Tandem Mass ◽  
Efficient Access ◽  
New Strategy ◽  
Fermentation Broths

Two hitherto unknown fusaricidins were obtained from fermentation broths of three Paenibacillus strains. After structure elucidation based on tandem mass spectrometry and NMR spectroscopy, fusaricidin E was synthesized to confirm the structure and the suggested stereochemistry. The synthesis was based on a new strategy which includes an efficient access to the 15-guanidino-3-hydroxypentadecanoyl (GHPD) side chain from erucamide.

Ion trap multiple-stage tandem mass spectrometry as a pre-NMR tool in the structure elucidation of saponins

2000 ◽  
Vol 11 (3) ◽  
pp. 190-198 ◽  
Author(s):  
Dirk C van Setten ◽  
Gijsbert Zomer ◽  
Gerrit van de Werken ◽  
Emmanuel J H J Wiertz ◽  
Bas R Leeflang ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Tandem Mass Spectrometry ◽  
Structure Elucidation ◽  
Ion Trap ◽  
Tandem Mass

scholarly journals Gas-Phase Fragmentation of Cyclic Oligosaccharides in Tandem Mass Spectrometry

Molecules ◽  
2019 ◽  
Vol 24 (12) ◽  
pp. 2226 ◽  
Author(s):  
Alexander O. Chizhov ◽  
Yury E. Tsvetkov ◽  
Nikolay E. Nifantiev
Keyword(s):  
Mass Spectrometry ◽  
Tandem Mass Spectrometry ◽  
Gas Phase ◽  
Structure Elucidation ◽  
Mass Spectra ◽  
Food Additives ◽  
Tandem Mass ◽  
Modern Mass ◽  
Gas Phase Fragmentation ◽  
Different Sources

Modern mass spectrometry, including electrospray and MALDI, is applied for analysis and structure elucidation of carbohydrates. Cyclic oligosaccharides isolated from different sources (bacteria and plants) have been known for decades and some of them (cyclodextrins and their derivatives) are widely used in drug design, as food additives, in the construction of nanomaterials, etc. The peculiarities of the first- and second-order mass spectra of cyclic oligosaccharides (natural, synthetic and their derivatives and modifications: cyclodextrins, cycloglucans, cyclofructans, cyclooligoglucosamines, etc.) are discussed in this minireview.

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